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[ASAP] Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00245




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[ASAP] Discovery of Potent Inhibitors against P-Glycoprotein-Mediated Multidrug Resistance Aided by Late-Stage Functionalization of a 2-(4-(Pyridin-2-yl)phenoxy)pyridine Analogue

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00337




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[ASAP] Discovery of <italic toggle="yes">N</italic>-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1<italic toggle="yes">H</italic>-pyrrolo[2,3-<italic toggle=&q

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00628




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[ASAP] Discovery of a Silicon-Containing Pan-Genotype Hepatitis C Virus NS5A Inhibitor

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00082




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[ASAP] Discovery and Optimization of Glucose Uptake Inhibitors

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02153




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[ASAP] Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00005




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[ASAP] Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00601




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[ASAP] Exploring the Implication of DDX3X in DENV Infection: Discovery of the First-in-Class DDX3X Fluorescent Inhibitor

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00681




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[ASAP] Discovery of BMS-986251: A Clinically Viable, Potent, and Selective ROR?t Inverse Agonist

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00063




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[ASAP] Discovery of a Potent Dual Inhibitor of Wild-Type and Mutant Respiratory Syncytial Virus Fusion Proteins

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00008




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[ASAP] Discovery of an Atropisomeric PI3Kß Selective Inhibitor through Optimization of the Hinge Binding Motif

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00095




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[ASAP] Discovery of CPI-1612: A Potent, Selective, and Orally Bioavailable EP300/CBP Histone Acetyltransferase Inhibitor

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00155




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[ASAP] Discovery of RO7185876, a Highly Potent ?-Secretase Modulator (GSM) as a Potential Treatment for Alzheimer’s Disease

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00109




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[ASAP] Discovery of Adamantane Carboxamides as Ebola Virus Cell Entry and Glycoprotein Inhibitors

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00025




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[ASAP] Substituted Azabicyclo[2.2.1]heptanes as Selective Orexin-1 Antagonists: Discovery of JNJ-54717793

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00085




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[ASAP] De-risking Drug Discovery of Intracellular Targeting Peptides: Screening Strategies to Eliminate False-Positive Hits

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00022




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The Origins of Public Diplomacy in US Statecraft: Uncovering a Forgotten Tradition / by Caitlin E. Schindler

Online Resource




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Secret wars: covert conflict in international politics / Austin Carson

Dewey Library - JZ1469.C37 2018




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Politics recovered: realist thought in theory and practice / edited by Matt Sleat

Dewey Library - JZ1307.P55 2018




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Rediscovering Korean cinema / edited by Sangjoon Lee

Dewey Library - PN1993.5.K6 R43 2019




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Deep imaging for visualizing nitric oxide in lipid droplets: discovering the relationship between nitric oxide and resistance to cancer chemotherapy drugs

Chem. Commun., 2020, Advance Article
DOI: 10.1039/D0CC01856B, Communication
Miantai Ye, Wei Hu, Meng He, Chenchen Li, Shuyang Zhai, Zhihong Liu, Yanying Wang, Huijuan Zhang, Chunya Li
A near-infrared two-photon fluorescent probe for selective detection and deep-depth imaging of NO helps to discover the relationship between NO and resistance to antitumor drugs.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Modified cation-exchange membrane for phosphate recovery in an electrochemically assisted adsorption–desorption process

Chem. Commun., 2020, 56,5046-5049
DOI: 10.1039/C9CC09563B, Communication
Kostadin V. Petrov, Laura Paltrinieri, Lukasz Poltorak, Louis C. P. M. de Smet, Ernst J. R. Sudhölter
A novel ion separation methodology using a cation-exchange membrane modified with iron oxide nanoparticles (Fe3O4 NPs) coated with polyhexamethylene guanidine (PHMG) is proposed.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Undercover user experience : learn how to do great UX work with tiny budgets, no time, and limited support / Cennydd Bowles and James Box

Bowles, Cennydd, author




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Leibniz discovers Asia: social networking in the Republic of Letters / Michael C. Carhart

Hayden Library - B2599.L35 C37 2019




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Discovery of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing 4-oxo-pyridazinone moiety as potential c-Met kinase inhibitors

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00575D, Paper
Binliang Zhang, Xiaobo Liu, Hehua Xiong, Qian Zhang, Xin Sun, Zunhua Yang, Shan Xu, Pengwu Zheng, Wufu Zhu
Two series of [1,2,4]triazolo[4,3-a]pyrazine derivatives bearing 4-oxo-pyridazinone moiety (compounds 21a-l and 22a-l) were designed and evaluated for the IC50 values against three cancer cell lines (A549, MCF-7 and Hela) and...
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] Discovery of Cephalosporin-3'-Diazeniumdiolates That Show Dual Antibacterial and Antibiofilm Effects against <italic toggle="yes">Pseudomonas aeruginosa</italic> Clinical Cystic Fibrosis Isolates and Efficacy in a Murine R

ACS Infectious Diseases
DOI: 10.1021/acsinfecdis.0c00070




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What To Do With These TIME Cover Originals?

Time Executive Editor J. Dana Tasker handled the retention or disposition of magazine cover art from around 1945 to 1953. While Time only acquired the first publication rights from the artists when commissioning a cover, Time frequently purchased and sent as a gift, or presented, the cover art to either the subject or a related...

The post What To Do With These TIME Cover Originals? appeared first on New-York Historical Society.




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Higher Education Support (Charges) Bill 2018 [provisions] ; Higher Education Support Amendment (Cost Recovery) Bill 2018 [provisions] / The Senate, Education and Employment Legislation Committee

Australia. Parliament. Senate. Education and Employment Legislation Committee, author, issuing body




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Modular systems for energy and fuel recovery and conversion / Yatish T. Shah

Online Resource




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3 country-made bombs recovered from car outside Uttar Pradesh Raj Bhawan



  • DO NOT USE Uttar Pradesh
  • India

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Dress code for UP Imambaras: ‘Head covered, no short dresses’ while framing rules for tourists



  • DO NOT USE Uttar Pradesh
  • India

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Selective recovery of Cr from electroplating nanosludge via crystal modification and dilute acid leaching

Environ. Sci.: Nano, 2020, Advance Article
DOI: 10.1039/D0EN00196A, Paper
Jiayi Zheng, Jiaxin Lv, Weizhen Liu, Zongren Dai, Huizhong Liao, Hong Deng, Zhang Lin
Amorphous nanosized particles in electroplating sludge are modified for selective extraction of heavy metals.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Discovery of new polymorphs of the tuberculosis drug isoniazid

CrystEngComm, 2020, 22,2705-2708
DOI: 10.1039/D0CE00440E, Communication
Keke Zhang, Noalle Fellah, Alexander G. Shtukenberg, Xiaoyan Fu, Chunhua Hu, Michael D. Ward
Two new metastable polymorphs of the tuberculosis drug isoniazid, considered monomorphic for sixty years, were discovered using melt crystallization and nanoscale confinement.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Data warehousing and knowledge discovery : 16th International Conference, DaWaK 2014, Munich, Germany, September 2-4, 2014 : proceedings / Ladjel Bellatreche, Mukesh K. Mohania (eds.)

DaWaK (Conference) (16th : 2014 : Munich, Germany),




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Transactions on large-scale data- and knowledge-centered systems. XXVI : special issue on data warehousing and knowledge discovery / Abdelkader Hameurlain, Josef Küng, Roland Wagner, Ladjel Bellatreche, Mukesh Mohania (Eds.)

DaWaK (Conference) (16th : 2014 : Munich, Germany),




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Failed CKP Co-operative Bank depositors among first beneficiaries of higher deposit cover

The bank which was under RBI's administration since 2014, failed to come up with a satisfactory revival plan, after which the banking regulator cancelled its license. Majority of the bank's depositors now get 100 per cent of their money back. The government hiked the minimum deposit insurance cover from Rs 1 lakh to Rs 5 lakh in its budget announcement in February.




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No SPG cover for Modi: Shinde

Union Home Minister Sushil Kumar Shinde Wednesday ruled out SPG cover for BJP''s prime ministerial candidate Narendra Modi.




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PCC chief slams CM on poor Aadhaar coverage

"If the CM cannot explain the failure of the state government in implementing the Aadhaar project, she must apologise,'' Bhattacharya said.




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After 2,200-yr old lion capital damaged at National Museum, staff try cover-up

The seven-feet long sculpture, weighing several tonnes, allegedly fell and broke into two halves during shifting.




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Recovery rests on global factors

In real estate, India ranks 182nd in construction permission processes, the Survey says, citing a World Bank report




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Recovery in sight; FIIs, oil prices key

The estimate takes into account a normal monsoon, further moderation in inflation and a mild recovery in global growth




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Punjab planning insurance cover for farmers

As reports of hailstorm-induced crop destruction pour in from various parts of Punjab and district heads prepare to assess the damage...




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Punjab''s cancer belt finds antidote in its dense cover of neem

While Punjab''s Malwa belt is witnessing rising incidence of cancer - largely due to addiction to alcohol and tobacco...




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A cover to help farmers weather dry spell, excess rains

With large parts of the country being declared drought-hit, the need for a safeguard against vagaries of nature is being felt like never before.




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Changing the way we think : using arts to inspire, empower and change your school community / Jennifer Little ; cover photography by Michael Torres

Little, Jennifer




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Coronavirus threatens Indian banks’ nascent recovery

Work to reduce bad corporate loans at risk of setback as fears grow for consumers




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Correction: Synthetic-biology-based discovery of a fungal macrolide from Macrophomina phaseolina

Org. Biomol. Chem., 2020, 18,3392-3392
DOI: 10.1039/D0OB90051F, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yohei Morishita, Terutaka Sonohara, Tohru Taniguchi, Kiyohiro Adachi, Makoto Fujita, Teigo Asai
The content of this RSS Feed (c) The Royal Society of Chemistry




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Astronomers discover closest black hole to earth, can be seen with naked eye

The finding was published in the journal Astronomy & Astrophysics.




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Whales of the Southern Ocean: Biology, Whaling and Perspectives of Population Recovery, / Yuri Makhalev

Online Resource




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Genomics data analysis: false discovery rates and empirical Bayes methods / David R. Bickel, University of Ottawa, Ottawa Institute of Systems Biology, Department of Biochemistry, Microbiology and Immunology, Department of Mathematics and Statistics

Dewey Library - QH438.4.S73 B53 2019