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A locally funded Puerto Rican parrot (Amazona vittata) genome sequencing project increases avian data and advances young researcher education

A locally funded Puerto Rican parrot (Amazona vittata) genome sequencing project increases avian data and advances young researcher education Oleksyk, Taras K.; Pombert, Jean-Francois; Siu, Daniel; Mazo-Vargas, Anyimilehidi; Ramos, Brian; Guiblet, Wilfried; Afanador, Yashira; Ruiz-Rodriguez, Christina T.; Nickerson, Michael L.; Logue, David M.; Dean, Michael; Figueroa, Luis; Valentin, Ricardo; Martinez-Cruzado, Juan-Carlos Background: Amazona vittata is a critically endangered Puerto Rican endemic bird, the only surviving native parrot species in the United States territory, and the first parrot in the large Neotropical genus Amazona, to be studied on a genomic scale. Findings: In a unique community-based funded project, DNA from an A. vittata female was sequenced using a HiSeq Illumina platform, resulting in a total of ~42.5 billion nucleotide bases. This provided approximately 26.89x average coverage depth at the completion of this funding phase. Filtering followed by assembly resulted in 259,423 contigs (N50=6,983 bp, longest=75,003 bp), which was further scaffolded into 148,255 fragments (N50=19,470, longest=206,462 bp). This provided ~76% coverage of the genome based on an estimated size of 1.58 Gb. The assembled scaffolds allowed basic genomic annotation and comparative analyses with other available avian whole-genome sequences. Conclusions: The current data represents the first genomic information from and work carried out with a unique source of funding. This analysis further provides a means for directed training of young researchers in genetic and bioinformatics analyses and will facilitate progress towards a full assembly and annotation of the Puerto Rican parrot genome. It also adds extensive genomic data to a new branch of the avian tree, making it useful for comparative analyses with other avian species. Ultimately, the knowledge acquired from these data will contribute to an improved understanding of the overall population health of this species and aid in ongoing and future conservation efforts. Sherpa Romeo green journal. Open access article. Creative Commons Attribution 2.0 (CC BY 2.0) applies




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India’s central bank offers mutual funds $6.6bn liquidity line

Authorities aiming to head off turmoil after Franklin Templeton fund freeze




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Lazy-Loading Disqus Comments

Lately, I've been obsessed with optimizing performance through lazy-loading. Recently, I've written on how to lazy-load Google Maps and on how to lazy-load responsive Google Adsense. Now it's time for Disqus, a service for embedding comments on your website. It's a great service. It eliminates the headache of developing your own local commenting system, dealing with spam, etc. Recently, I've been working on implementing the widget in one of my projects.

I've written an article on that and got it published on CSS-Tricks.

Read the article

Try the Demo

You can also contribute, follow the project on GitHub.




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Container-Adapting Tabs With "More" Button

Or the priority navigation pattern, or progressively collapsing navigation menu. We can name it in at least three ways..

There are multiple UX solutions for tabs and menus and each of them have their own advantages over another, you just need to pick the best for the case you are trying to solve. At design and development agency Kollegorna we were debating on the most appropriate UX technique for tabs for our client’s website…

I wrote an article, coded a demo and got it all published on CSS-Tricks — you're very welcome to read, try and use it!

Read the article

Try the demo




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Superconductivity in nanowires: fabrication and quantum transport / Alexey Bezryadin

Barker Library - TK7874.85.B49 2013




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Characterization of semiconductor heterostructures and nanostructures / edited by Carlo Lamberti and Giovanni Agostini, University of Torino, Department of Chemistry, Via Quarello 11, I-10135 Torino, Italy

Barker Library - QC176.8.N35 C43 2013




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Solution synthesis of inorganic functional materials -- films, nanoparticles and nanocomposites: symposium held April 1-5, 2013, San Francisco, California, U.S.A. / editors, Menka Jain, Quanxi Jia, Teresa Puig, Hiromitsu Kozuba

Hayden Library - TA418.9.N35 S656 2013




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Semiconductor nanowires: optical and electronic characterization and applications: November 25-30, 2012, Boston, Massachusetts, USA / editors J. Arbiol, P.S. Lee, J. Piqueras, D.J. Sirbuly

Hayden Library - TK7874.85.S474 2012




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Emerging nanotechnologies for manufacturing / edited by Waqar Ahmed, Mark Jackson

Barker Library - T174.7.A364 2014




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Magnetic nano- and microwires: design, synthesis, properties and applications / edited by Manuel Vázquez

Barker Library - TK7874.85




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Quaternary ecology, evolution and biogeography [electronic resource] / Valentí Rull.

London : Academic Press, 2020.




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A modular approach to the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine

Org. Biomol. Chem., 2020, 18,3047-3068
DOI: 10.1039/D0OB00078G, Paper
Ramona Schütz, Maximilian Meixner, Iris Antes, Franz Bracher
A modular short-step synthesis of the bisbenzylisoquinoline alkaloids tetrandrine and isotetrandrine was developed employing N-acyl-Pictet–Spengler reaction and Ullman diaryl ether synthesis as central steps.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The silver catalyzed direct C–H functionalization of quinones with dialkyl amides

Org. Biomol. Chem., 2020, 18,3027-3031
DOI: 10.1039/D0OB00323A, Communication
Sakthivel Pandaram, Adarsh Krishna T. P., Andivelu Ilangovan
A novel and efficient strategy for the direct C–H amidoalkylation of quinones via a radical pathway has been achieved using readily available alkyl amides and an AgNO3-TBHP catalyst system. This is the first ever example of the synthesis of novel amidoquinone derivatives.
The content of this RSS Feed (c) The Royal Society of Chemistry




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The ruthenium(II)-catalyzed C–H olefination of indoles with alkynes: the facile construction of tetrasubstituted alkenes under aqueous conditions

Org. Biomol. Chem., 2020, 18,3158-3163
DOI: 10.1039/D0OB00508H, Paper
Ming Li, Tian-Yu Yao, Sheng-Zheng Sun, Ting-Xun Yan, Li-Rong Wen, Lin-Bao Zhang
An environmentally-friendly and facile protocol for the construction of tetrasubstituted alkenes has been established with Ru(II)-catalyzed C–H bond functionalizations under mild conditions.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Catalyst and solvent switched divergent C–H functionalization: oxidative annulation of N-aryl substituted quinazolin-4-amine with alkynes

Org. Biomol. Chem., 2020, 18,3032-3037
DOI: 10.1039/D0OB00318B, Communication
Siddi Ramulu Meesa, Praveen Kumar Naikawadi, Kishan Gugulothu, K. Shiva Kumar
Catalyst and solvent controlled ortho/peri site-selective oxidative annulation of C–H bonds of N-aryl substituted quinazolin-4-amines with internal alkynes.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Experimental results and computational insight into sequential reactions of β-(2-aminophenyl)-α,β-ynones with aryl isocyanates/benzoyl isothiocyanate

Org. Biomol. Chem., 2020, 18,3177-3189
DOI: 10.1039/D0OB00087F, Paper
Antonio Arcadi, Massimiliano Aschi, Marco Chiarini, Fabio Marinelli, Vincenzo Marsicano, Gustavo Portalone
The selective formation of quinazoline vs. benzoxazine  and benzothiazine derivatives from β-(2-aminophenyl)-α,β-ynones and aryl isocyanates/benzoyl isothiocyanate was explored. DFT calculations provide a plausible rationale.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Photocatalytic xanthate-based radical addition/cyclization reaction sequence toward 2-biphenyl isocyanides: synthesis of 6-alkylated phenanthridines

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00136H, Communication
Pedro López-Mendoza, Luis D. Miranda
A photocatalytic xanthate-based radical addition/cyclization reaction cascade toward 2-biphenylisocyanides is described as a practical and modular approach to 6-alkylated phenanthridines.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis and photophysical properties of selenopheno[2,3-b]quinoxaline and selenopheno[2,3-b]pyrazine heteroacenes

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00718H, Paper
Amol Sonawane, Atsushi Shimozuma, Taro Udagawa, Masayuki Ninomiya, Mamoru Koketsu
In this paper, we report the novel synthesis of three different heterocycles namely 2-arylselenopheno[2,3-b]quinoxaline, 3-(aryl/alkylselanyl)-2-arylselenopheno[2,3-b]quinoxaline and 6-phenyl-7-(arylselanyl)selenopheno[2,3-b]pyrazine derivatives from the corresponding 2,3-dichloroquinoxaline and 2,3-dichloropyrazine derivatives. Further, photophysical properties were investigated...
The content of this RSS Feed (c) The Royal Society of Chemistry




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The quasi-irreversible inactivation of cytochrome P450 enzymes by paroxetine: a computational approach

Org. Biomol. Chem., 2020, 18,3334-3345
DOI: 10.1039/D0OB00529K, Paper
Emadeldin M. Kamel, Al Mokhtar Lamsabhi
The potency of paroxetine as a P450 inhibitor is mainly attributed to the availability of two active sites on its structure, its compatibility with P450's active site and the ease of its tight coordination to heme iron.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Synthesis of methylene cyclopropane-fused chromenes and dihydroquinolines by sequential [4 + 2]- and [1 + 2]-annulation

Org. Biomol. Chem., 2020, 18,3303-3311
DOI: 10.1039/D0OB00389A, Paper
Tianyu Lu, Xuange Zhang, Zhiwei Miao
A base promoted sequential [4 + 2]- and [1 + 2]-annulation of 2-hydroxychalcones or 2-tosylaminochalcones with prop-2-ynylsulfonium salts was developed.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Base-promoted 1,6-conjugate addition of alkylazaarenes to para-quinone methides

Org. Biomol. Chem., 2020, 18,3354-3359
DOI: 10.1039/D0OB00419G, Paper
Amritha Rayaroth, Rajat Kumar Singh, Kalyanakrishnan A. V., Krishna Hari, Alagiri Kaliyamoorthy
1,1,2-Triarylethanes embedded with an azaarene unit were prepared in a single step at ambient temperature via the sodium hexamethyldisilazide mediated 1,6-conjugate addition of unactivated alkylazaarenes on para-quinone methides (p-QMs).
The content of this RSS Feed (c) The Royal Society of Chemistry




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KI/TBHP-promoted [3 + 2] cycloaddition of pyrrolo[1,2-a]quinoxalines and N-arylsulfonylhydrazones

Org. Biomol. Chem., 2020, 18,3360-3366
DOI: 10.1039/D0OB00494D, Paper
Zhen Yang, Jing He, Yueting Wei, Weiwei Li, Ping Liu
A series of diverse fused [1,2,4]triazolo[3,4-c]quinoxalines was obtained by an efficient KI/TBHP-promoted [3 + 2] cycloaddition of pyrrolo[1,2-a]quinoxalines and N-arylsulfonylhydrazones.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Gold(III)-catalyzed azide-yne cyclization/O–H insertion cascade reaction for the expeditious construction of 3-alkoxy-4-quinolinone frameworks

Org. Biomol. Chem., 2020, Advance Article
DOI: 10.1039/D0OB00745E, Paper
Jingjing Huang, Han Su, Ming Bao, Lihua Qiu, Yuanqing Zhang, Xinfang Xu
A gold-catalyzed cascade reaction has been developed, and it provides an expeditious access to 3-alkoxy-4-quinolines and applications in alkaloid synthesis.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Dienaminodioate based multicomponent reactions with post-benzylic oxidative transformations mediated by DDQ

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00721H, Paper
Jaice Ravindran, Velickakathu Yadhukrishnan, Reghuvaran Asha , Ravi Shankar Lankalapalli
Multicomponent reactions (MCRs) using dienaminodioate with post-benzylic oxidative transformation by DDQ that afforded a diverse array of products is described. An unprecedented rearrangement of 1,2-dihydropyridines (1,2-DHPs), 3CR products, to 2-pyridones...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Highly modified steroids from Inonotus obliquus

Org. Biomol. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0OB00474J, Paper
Chun-Xin Zou, Zilin Hou, Ming Bai, Rui Guo, Bin Lin, Xiaobo Wang, Xiaoxiao Huang, Shaojiang Song
Six undescribed steroids were isolated from the fungus Inonotus obliquus. Notably, compounds 1 and 2 represented the first example of 8, 14-seco-4-methylpregnane. By spectroscopic data analyses, quantum chemical calculations and...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Urban Ministry questions Delhi govt's move to set up SEZs

The Centre has questioned the legality of SEZs in absence of any provision for the same in the Master Plan Delhi (MPD) 2021.




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UP: 63 flee quarantine centre, all traced




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E-tokens fail to take off; liquor shops see rush

Booze lovers continued to throng liquor shops in the city, even as the e-token system introduced by the Delhi government could not fully take off due to heavy traffic on the designated website.




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Fake sites offer liquor at doorstep in Delhi

The excise department has filed a complaint with Crime Branch of Delhi Police against fake websites claiming to deliver liquor at people's doorsteps. The websites became active a day after Delhi government announced an e-token delivery system to avoid chaos at liquor shops.




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Delhi: Liquor hunt shifts online, site crashes

The Delhi government's initiative to reduce crowding outside liquor stores by issuing e-tokens - one could book a time slot to buy the tipple without getting into long queues - failed to work as the excise department website crashed due to heavy rush late Thursday.




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Funds for salaries late, inadequate: DU colleges

For the second time this year, Delhi government has allegedly released inadequate funds for the salaries of teaching and non-teaching staff of 12 Delhi University colleges, that too after a month-long delay.




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Indian researchers start working on genome sequencing of novel coronavirus

In the next 3-4 weeks researchers would be able to get at least 200-300 isolates and this information would help them to make some further conclusion about the behaviour of this virus.




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'Sky Is Pink required big stars'

'There is never a safe choice in the movie business.''Everything is chance.'






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He quit a well paying job to write Bala

'The most difficult thing in the world is to convince someone to put Rs 20 crore on your movie script.'




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The Queen of 'Item Numbers'

'It's a special song and every girl will relate to it.'





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[ASAP] Modifying the Electrocatalyst–Ionomer Interface via Sulfonated Poly(ionic liquid) Block Copolymers to Enable High-Performance Polymer Electrolyte Fuel Cells

ACS Energy Letters
DOI: 10.1021/acsenergylett.0c00532




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Modeling of FRP strengthening techniques in concrete infrastructure: held at the ACI Fall 2011 Convention: Toronto, Ontario, Canada, 21-25 October 2011.

Barker Library - TA443.P58 M63 2015




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Development of ultra-high performance concrete against blasts: from materials to structures / Chengqing Wu, Jun Li, Yu Su

Barker Library - TA439.W8 2018




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Quantum Vibe for Friday, Apr 10, 2020

Straight to Snake-Eyes




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Quantum Vibe for Monday, Apr 13, 2020

Tough-guy lawman




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Quantum Vibe for Wednesday, Apr 15, 2020

Not exactly born yesterday




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Quantum Vibe for Friday, Apr 17, 2020

Not that entire group of satrapies.




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Quantum Vibe for Monday, Apr 20, 2020

An all-hands-on-deck situation




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Quantum Vibe for Wednesday, Apr 22, 2020

Keeping up with the news.




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Quantum Vibe for Friday, Apr 24, 2020

Nebula of foreboding




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Quantum Vibe for Monday, Apr 27, 2020

Not everyone is a pessimist




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Quantum Vibe for Wednesday, Apr 29, 2020

A gang of non-conformists