The City of Timmins says a COVID-19 outbreak remains in place at a long-term care home in the city, even after the one affected resident has now tested negative — twice.

The following is a guest post by Katherine Blood, Curator of Fine Prints, Prints & Photographs Division. As the Library of Congress marks its 220th year of serving the nation, the publication of a new guide tells two stories: how staff have for decades worked with art professionals to build the collections and how by […]

The following is a post by Kristi Finefield, Reference Specialist in the Prints & Photographs Division, and member of the Picture This blog team. As the Library of Congress marks its 220th year, we take the opportunity to explore one example of its efforts to sustain and celebrate the arts in its physical spaces. Above […]

This rapid and efficient method to prepare highly purified recombinant adeno-associated viruses (rAAVs) is based on binding of negatively charged rAAV capsids to an anion-exchange resin that is pH dependent.

This is a simple method for rapid preparation of recombinant adeno-associated virus (rAAV) stocks, which can be used for in vivo gene delivery. The purity of these vectors is considerably lower than that obtained by either CsCl gradient centrifugation or by combination of iodixanol gradient ultracentrifugation followed by column chromatography.

Over many years, the Xenopus laevis embryo has provided a powerful model system to investigate how mechanical forces regulate cellular function. Here, we describe a system to apply reproducible tensile and compressive force to X. laevis animal cap tissue explants and to simultaneously assess cellular behavior using live confocal imaging.

In this protocol, DNA fragments are separated according to size by electrophoresis through low-melting-temperature agarose, and then recovered by melting the agarose and extracting with phenol:chloroform. The protocol works best for DNA fragments ranging in size from 0.5 to 5.0 kb. Yields of DNA fragments outside this range are usually lower, but often are sufficient for many purposes.

The 700-bp A homology arm (A-box) and the 700-bp B homology arm (B-box) are amplified by polymerase chain reaction (PCR) using purified bacterial artificial chromosome (BAC) DNA as template for two-step BAC engineering. The resulting A-box PCR product contains an AscI site at its 5' end (the 5' primer incorporates an AscI site, and the 3' primer does not incorporate any restriction sites). The B-box PCR product contains an XmaI site at its 3' end (the 5' primer does not incorporate any restriction sites, and the 3' primer incorporates an XmaI site). The amplification products are then digested with the appropriate restriction endonucleases to render them suitable for cloning into the shuttle vector.

The liquidity trap is synonymous with ineffective monetary policy. The common wisdom is that, as the short-term interest rate nears its effective lower bound, monetary policy cannot do much to stimulate the economy. However, central banks have resorted to alternative instruments, such as QE, credit easing and forward guidance.

This paper studies the relationship between bank geographic complexity and risk. We use a unique dataset of 96 bank holding companies around the world to measure the geographic dispersion of their affiliates. We study how this dispersion interacts with economic and regulatory conditions to affect the riskiness of the bank.

FSI Briefs No 3, April 2020. In response to the 2007-09 Great Financial Crisis (GFC), accounting standard setters introduced a new methodology to value loans based on expected credit losses (ECL). The previous approach, based on incurred losses, was viewed as procyclical and inconsistent with prudential objectives. In the wake of the Covid-19 pandemic, several prudential authorities and the Basel Committee on Banking Supervision (BCBS), introduced a series of measures to clarify how banks should consider various public and private debt relief programmes in their ECL estimates and in their calculation of regulatory capital. These measures are intended to incentivise banks to continue supporting the real economy, while reducing pressure on banks' ECL provisions, earnings and regulatory capital. Supervisory initiatives that provide capital relief should be augmented by severe constraints on the payment of dividends, bonuses and share buybacks. These joint actions will simultaneously expand banks' lending capacity and enhance their ability to absorb losses. Prudential authorities face difficult trade-offs as they confront the most severe economic crisis in modern times. Encouraging the use of flexibility in applicable accounting standards, while preserving market trust and transparency in the reported financial statements of banks, will be key in fostering both economic and financial stability.

Even celebrity chef Julia Child said that the sleek appliance made mixing 'marvelous'

Press release: CPMI and IOSCO share authorities´ experiences in cooperation to increase FMI safety and efficiency, 10 December 2019

The BIS Board of Directors has decided to invite the central banks of Kuwait, Morocco and Vietnam to become members of the BIS. This is the first such expansion since 2011 and will take the number of members to 63.

Markets Committee calls for wider adoption of global code of conduct for foreign exchange markets (Press release, 30 January 2020)

Press release about Basel Committee assesses members' implementation of the Net Stable Funding Ratio and large exposures framework, 19 March 2020

It works like a very fine "molecular knob" able to modulate the electrical activity of the neurons of our cerebral cortex, crucial to the functioning of our brain.

The American Geriatrics Society annually honors researchers, clinicians, educators, and emerging health professionals who have made outstanding contributions to high-quality, person-centered care for older people.

In a pandemic, it’s not just truth against misinformation. Every choice is an experiment.

Baseball Hall of Famer Andre Dawson spoke to CBC's John Northcott about the realities of running a funeral home during the pandemic.

Major League Baseball owners will discuss a length for the amateur draft next week and are likely to start the selections on the original date of June 10, a person familiar with the deliberations told The Associated Press.

Matt Keough, the former Oakland Athletics pitcher and special assistant, has died. He was 64. He was an American League all-star as a rookie in 1978 and two years later comeback player of the year.

A former groundskeeper for the Expos recently told the Montreal Gazette that Pete Rose, who played less than a full season with the team, routinely had an Olympic Stadium staffer cork his bats in 1984.

Earlier this week, Manitoba's premier announced $200 cheques for seniors to help pay for increased costs during the COVID-19 pandemic. But some wonder if there is a better way to help those in need.

With Mother's Day only a few days away, businesses are coming up with creative ways to help your family celebrate. Everything from brunch in a box to colourful bouquets and home delivered chocolate.

A petition is being circulated to get a $600,000 bridge replacement project near Millvale scrapped.

Authorities investigating Flint's water crisis have used search warrants to seize from storage the state-owned mobile devices of former Gov. Rick Snyder and 65 other current or former officials, The Associated Press has learned.

A former FBI agent who investigated the Flint water scandal says the team was moving toward new charges when new prosecutors took over.

The exchange-traded derivatives statistics provide monthly data on the turnover, and quarterly data on the open interest, of foreign exchange and interest rate futures and options. They refer to notional amounts, which enables comparisons of levels and trends in activity across different markets.

Long-term interest rates have remained low despite a surge in the issuance of sovereign debt to mitigate the economic impact of the pandemic.

Interview with Mr Luis de Guindos, Vice-President of the European Central Bank, and Expresso, conducted by Mr João Silvestre on 15 April 2020.

National Basketball Association executives and player agents are calling on the league to cancel the remainder of the 2019-20 season due to health concerns over the novel coronavirus outbreak, CNBC reported on Thursday.

With ‘Four More Shots Please!,’ India Gets Its Own ‘Sex and the City’  The New York Times

11 startups to pitch at NEXT Canada's virtual Venture Reveal  BetaKit

Happy birthday Vijay Deverakonda: Tollywood's 'Dear Comrade' who auctioned his first Filmfare Award for charity  The New Indian Express

Sound of hope  The New Indian Express

5 Dance Moves Made Popular By Salman Khan Which Prove Sometimes Even ‘Pappu Can Dance Saala’  MensXP.com

Inside Pic: Can You Identify Madhuri Dixit In This Throwback Picture with Her Sister?  సాక్షి

Made in India: How Covid-19 is changing the luxe living room  The Hindu

In isolation with dog Charlie, Canadian soccer legend Christine Sinclair recalls "dream come true" of 2012 Olympic bronze and "heartbreak" of repeat in Rio in an interview with CBC Sports.

A federal judge threw out the unequal pay claim by players on the U.S. women's national soccer team but allowed their allegation of discriminatory travel accommodations and medical support services to go to trial.

There has been a marked change in volatility levels in the FX markets in recent weeks. At the start of...

The post Why FX Traders Are Looking at the Short and Long Term appeared first on OpenMarkets.

A few things will go back to “normal” once the COVID-19 pandemic is under control, but somethings may not. The...

The post After Price Wars and A Pandemic, What’s Next for U.S. Shale? appeared first on OpenMarkets.

The volatility experienced this spring in the 7 trillion-dollar foreign exchange market was unprecedented. The JP Morgan G7 FX Volatility...

The post OpenMarkets Weekly: FX Volatility appeared first on OpenMarkets.

The number of cases of COVID-19 in First Nations reserves continues to rise this week, with 161 confirmed positive cases reported as of May 5.

Award-winning children's book explores big questions about colonization and identity.

CBC Kitchener-Waterloo speaks to a motherhood expert about managing work and child care during the pandemic.