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Dissertatio medica, exhibens cogitationes physiologicas de vita, et vivificatione materiae humanum corpus constituentis / Joanni Theodoro vander Kemp.

Edinburgi : Excudebant Balfour et Smellie, 1782.




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A dissertation on the varied direction of the fibres of the muscles, and on the effects of this upon the movements of the body : with an appendix ... / by Alex. Monro.

Edinburgh : [publisher not identified], 1812.




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Dissertationes medicæ in Universitate Vindobonensi habitæ ad morbos chronicos pertinentes / Max. Stollii ; edidit et præfatus est Josephus Eyerel.

Viennæ : Typis Christiani Friderici Wappler, 1788-92.




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Drei Falle von Hydrops ovarii. Inaugural-Dissertation ... / vorgelegt von A. Müller.

Rostock : Druck von Carl Boldt, 1857.




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Du cancer de l'uterus au point de vue de la de la conception de la grossesse et de l'accouchement / par Gustave Chantreuil.

Paris : A. Delahaye, 1872.




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Du développement du foetus chez les femmes a bassin vicié : recherches cliniques au point de vue de l’accouchement prématuré artificiel / par Felice la Torre.

Paris : O. Doin, 1887.




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Du manuel opératoire de l’hystérectomie vaginale / par M. Malapert.

Paris : Société d’éditions scientifiques, 1893.




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Du molluscum : recherches critiques sur les formes, la nature et le traitement des affections cutanées de ce nom, suivies de la description détaillée d'une nouvelle variété / par Maximilien Maurice Jacobovics.

Londres : Paris, 1840.




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Du retrécissement cicatriciel du col de l'utérus au point de vue de l'accouchement / par Victor-Albert Taurin.

Paris : G. Steinheil, 1895.




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The dwelling house / by George Vivian Poore.

London : Longmans, Green, 1897.




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The earth in relation to the preservation and destruction of contagia : being the Milroy lectures delivered at the Royal College of Physicians in 1899, with other papers on sanitation / by George Vivian Poore.

London : Longmans, Green, 1902.




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The effects of cross and self fertilisation in the vegetable kingdom / by Charles Darwin.

London : John Murray, 1876.




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Ein Apparat, welcher gestattet, die Gesetze von Filtration und Osmose stromender Flussigkeiten bei homogenen Membranen zu studiren / von H.J. Hamburger.

Amsterdam : J. Muller, 1895.




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Ein Beitrag zur Lehre vom Abortus und vom fibrinosen Uteruspolypen / von C. Rokitansky.

Wien : C. Ueberreuter, 1860.




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Ein Beitrag zur Lehre vom engen Becken : Inaugural-Dissertation ... / vorgelegt von Fritz Ebeling.

Tubingen : H. Laupp, Jr, 1889.




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Ein Beitrag zur Lehre von den Lesestörungen auf Grund eines Falles von Dyslexie / von S. Weissenberg.

Berlin : L. Schumacher, 1890.




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Ein Beitrag zur Lehre von der Eiterung / von Albert Dubler.

Basel : Sallmann & Bonacker, 1890.




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Ein Beitrag zur Lehre von der sensorischen Aphasie / von Hermann Entzian.

Jena : Druck von Bernhard Vopelius, 1899.




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Einleitung in die vergleichende gehirnphysiologie und Vergleichende psychologie : mit besonderer berücksichtigung der wirbellosen thiere / von Jacques Loeb.

Leipzig : J.A. Barth, 1899.




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Electric waves : being researches on the propagation of electric action with finite velocity through space / by Heinrich Hertz ; authorised English translation by D.E. Jones ; with a preface by Lord Kelvin.

London : Macmillan, 1893.




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Elémens de physiologie végétale et de botanique / par C. F. Brisseau-Mirbel.

Paris : chez Magimel, 1815.




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Eminent medical men of Asia, Africa, Europe and America, who have advanced medical science; for the use of students and for the Vydians and Hakims of India / by Edward Balfour.

Madras : printed by C. Foster, 1876.




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Epidemiology, or, The remote cause of epidemic diseases in the animal and in the vegetable creation ... Part 1 / by John Parkin.

London : J. & A. Churchill, 1873.




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Ergebnisse von 240 operierten Lupusfällen nebst Bemerkungen zur modernen Lupusbehandlung / von Ludwig Spitzer und Alfred Jungmann.

Wien : SafÏar, 1905.




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Esquisse de nosographie vétérinaire / par J.-B. Huzard.

Paris : M. Huzard, 1820.




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Essai de sémiologie urinaire; méthodes d'interprétation de l'analyse urologique. L'urine dans les divers états morbides / par Camille Vieillard ; preface par Albert Robin.

Paris : Société d’éditions scientifiques, 1901.




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E.M. Curr's Australian Comparative Vocabulary

At 9.45 metres long, this gargantuan accordion-fold document is  the longest known manuscript in the Library*.  Curr




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Despite Fierce Teacher Opposition, West Virginia House Votes to Allow Charter Schools

The West Virginia House of Delegates passed its version of a sweeping education omnibus bill, which would allow the state's first charter schools.




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Roman Catholic Students Sue Vermont Over Dual-Enrollment Lockout

A group of Vermont high school students backed by a powerful conservative Christian legal organization is accusing the state of religious discrimination.




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A rich man and a woman who has visited him for tea gossip about an impoverished gentleman's daughter who is present in his house as a governess: the visitor looks at the governess with a supercilious expression. Engraving by R. Hatfield, 1842, after R

London (No. 4, Hanover Street) : Published ... for the proprietor by T.G. March ; [London] (Threadneedle Street) : Sold also by F. G. Moon ; [London] (Strand) : [Sold also by] Ackermann & Co., April 10, 1842 ([London?] : Printed by R. Lloyd)




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The works of that famous chirurgeon Ambrose Parey / translated out of Latin ; and compared with the French, by Th. Johnson ; together with three tractates concerning the veins, arteries, and nerves: exemplified with large anatomical figures. Translated

London : Printed by Mary Clark, and are to be sold by John Clark, at Mercers Chappel at the Lower End of Cheapside, MDCLXXVIII. [1678]




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Poligny (Jura), France: an ancient mosaic floor at the villa of Estavage (Chambrettes), including figures of gryphons and centaurs. Line engraving.




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The device of the Emperor Charles V surrounding initials of the artist Pieter Coecke van Aelst. Process print, 1873.




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Fruit on a dish and a tureen, with elaborate vessels, rugs, and a bas-relief of grape-pickers. Colour line block by Leighton Brothers after G. Lance.

[London?] : [Illustrated London News?], [between 1850 and 1870?]




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The death of the Venerable Bede. Photograph after W.B. Scott.

[19--?]




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The skeleton of a horse: right side view. Line engraving with etching by A. Bell, ca. 1790.

[Edinburgh], [between 1788 and 1797]




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These #HockeyAtHome videos are ridiculously fun and creative

NHL fans have to stay busy somehow, right? Their HockeyAtHome videos are almost too good to be true. By Brooke Destra




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This Date in Bruins History: B's get revenge vs. Flyers with 2011 sweep

The Boston Bruins didn't take long to put the painful memory of the 2010 Stanley Cup Playoffs behind them.




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Parce que, travestis et transgenres, notre regard sur le mode et les autres se veut teinté de respect et de douceur / Hommefleur.

Châtillon, France : Association Hommefleur, [date of publication not identified]




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Report on Harrogate visit / by L. S. P. Davidson.

England : Harrogate Corporation, Wells and Baths Department, 1945.




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Nonconcave penalized estimation in sparse vector autoregression model

Xuening Zhu.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1413--1448.

Abstract:
High dimensional time series receive considerable attention recently, whose temporal and cross-sectional dependency could be captured by the vector autoregression (VAR) model. To tackle with the high dimensionality, penalization methods are widely employed. However, theoretically, the existing studies of the penalization methods mainly focus on $i.i.d$ data, therefore cannot quantify the effect of the dependence level on the convergence rate. In this work, we use the spectral properties of the time series to quantify the dependence and derive a nonasymptotic upper bound for the estimation errors. By focusing on the nonconcave penalization methods, we manage to establish the oracle properties of the penalized VAR model estimation by considering the effects of temporal and cross-sectional dependence. Extensive numerical studies are conducted to compare the finite sample performance using different penalization functions. Lastly, an air pollution data of mainland China is analyzed for illustration purpose.




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Differential network inference via the fused D-trace loss with cross variables

Yichong Wu, Tiejun Li, Xiaoping Liu, Luonan Chen.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1269--1301.

Abstract:
Detecting the change of biological interaction networks is of great importance in biological and medical research. We proposed a simple loss function, named as CrossFDTL, to identify the network change or differential network by estimating the difference between two precision matrices under Gaussian assumption. The CrossFDTL is a natural fusion of the D-trace loss for the considered two networks by imposing the $ell _{1}$ penalty to the differential matrix to ensure sparsity. The key point of our method is to utilize the cross variables, which correspond to the sum and difference of two precision matrices instead of using their original forms. Moreover, we developed an efficient minimization algorithm for the proposed loss function and further rigorously proved its convergence. Numerical results showed that our method outperforms the existing methods in both accuracy and convergence speed for the simulated and real data.




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Pitfalls of significance testing and $p$-value variability: An econometrics perspective

Norbert Hirschauer, Sven Grüner, Oliver Mußhoff, Claudia Becker.

Source: Statistics Surveys, Volume 12, 136--172.

Abstract:
Data on how many scientific findings are reproducible are generally bleak and a wealth of papers have warned against misuses of the $p$-value and resulting false findings in recent years. This paper discusses the question of what we can(not) learn from the $p$-value, which is still widely considered as the gold standard of statistical validity. We aim to provide a non-technical and easily accessible resource for statistical practitioners who wish to spot and avoid misinterpretations and misuses of statistical significance tests. For this purpose, we first classify and describe the most widely discussed (“classical”) pitfalls of significance testing, and review published work on these misuses with a focus on regression-based “confirmatory” study. This includes a description of the single-study bias and a simulation-based illustration of how proper meta-analysis compares to misleading significance counts (“vote counting”). Going beyond the classical pitfalls, we also use simulation to provide intuition that relying on the statistical estimate “$p$-value” as a measure of evidence without considering its sample-to-sample variability falls short of the mark even within an otherwise appropriate interpretation. We conclude with a discussion of the exigencies of informed approaches to statistical inference and corresponding institutional reforms.




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A comparison of spatial predictors when datasets could be very large

Jonathan R. Bradley, Noel Cressie, Tao Shi.

Source: Statistics Surveys, Volume 10, 100--131.

Abstract:
In this article, we review and compare a number of methods of spatial prediction, where each method is viewed as an algorithm that processes spatial data. To demonstrate the breadth of available choices, we consider both traditional and more-recently-introduced spatial predictors. Specifically, in our exposition we review: traditional stationary kriging, smoothing splines, negative-exponential distance-weighting, fixed rank kriging, modified predictive processes, a stochastic partial differential equation approach, and lattice kriging. This comparison is meant to provide a service to practitioners wishing to decide between spatial predictors. Hence, we provide technical material for the unfamiliar, which includes the definition and motivation for each (deterministic and stochastic) spatial predictor. We use a benchmark dataset of $mathrm{CO}_{2}$ data from NASA’s AIRS instrument to address computational efficiencies that include CPU time and memory usage. Furthermore, the predictive performance of each spatial predictor is assessed empirically using a hold-out subset of the AIRS data.




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Discrete variations of the fractional Brownian motion in the presence of outliers and an additive noise

Sophie Achard, Jean-François Coeurjolly

Source: Statist. Surv., Volume 4, 117--147.

Abstract:
This paper gives an overview of the problem of estimating the Hurst parameter of a fractional Brownian motion when the data are observed with outliers and/or with an additive noise by using methods based on discrete variations. We show that the classical estimation procedure based on the log-linearity of the variogram of dilated series is made more robust to outliers and/or an additive noise by considering sample quantiles and trimmed means of the squared series or differences of empirical variances. These different procedures are compared and discussed through a large simulation study and are implemented in the R package dvfBm.




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Relevance Vector Machine with Weakly Informative Hyperprior and Extended Predictive Information Criterion. (arXiv:2005.03419v1 [stat.ML])

In the variational relevance vector machine, the gamma distribution is representative as a hyperprior over the noise precision of automatic relevance determination prior. Instead of the gamma hyperprior, we propose to use the inverse gamma hyperprior with a shape parameter close to zero and a scale parameter not necessary close to zero. This hyperprior is associated with the concept of a weakly informative prior. The effect of this hyperprior is investigated through regression to non-homogeneous data. Because it is difficult to capture the structure of such data with a single kernel function, we apply the multiple kernel method, in which multiple kernel functions with different widths are arranged for input data. We confirm that the degrees of freedom in a model is controlled by adjusting the scale parameter and keeping the shape parameter close to zero. A candidate for selecting the scale parameter is the predictive information criterion. However the estimated model using this criterion seems to cause over-fitting. This is because the multiple kernel method makes the model a situation where the dimension of the model is larger than the data size. To select an appropriate scale parameter even in such a situation, we also propose an extended prediction information criterion. It is confirmed that a multiple kernel relevance vector regression model with good predictive accuracy can be obtained by selecting the scale parameter minimizing extended prediction information criterion.




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Efficient Characterization of Dynamic Response Variation Using Multi-Fidelity Data Fusion through Composite Neural Network. (arXiv:2005.03213v1 [stat.ML])

Uncertainties in a structure is inevitable, which generally lead to variation in dynamic response predictions. For a complex structure, brute force Monte Carlo simulation for response variation analysis is infeasible since one single run may already be computationally costly. Data driven meta-modeling approaches have thus been explored to facilitate efficient emulation and statistical inference. The performance of a meta-model hinges upon both the quality and quantity of training dataset. In actual practice, however, high-fidelity data acquired from high-dimensional finite element simulation or experiment are generally scarce, which poses significant challenge to meta-model establishment. In this research, we take advantage of the multi-level response prediction opportunity in structural dynamic analysis, i.e., acquiring rapidly a large amount of low-fidelity data from reduced-order modeling, and acquiring accurately a small amount of high-fidelity data from full-scale finite element analysis. Specifically, we formulate a composite neural network fusion approach that can fully utilize the multi-level, heterogeneous datasets obtained. It implicitly identifies the correlation of the low- and high-fidelity datasets, which yields improved accuracy when compared with the state-of-the-art. Comprehensive investigations using frequency response variation characterization as case example are carried out to demonstrate the performance.




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Bayes and empirical-Bayes multiplicity adjustment in the variable-selection problem

James G. Scott, James O. Berger

Source: Ann. Statist., Volume 38, Number 5, 2587--2619.

Abstract:
This paper studies the multiplicity-correction effect of standard Bayesian variable-selection priors in linear regression. Our first goal is to clarify when, and how, multiplicity correction happens automatically in Bayesian analysis, and to distinguish this correction from the Bayesian Ockham’s-razor effect. Our second goal is to contrast empirical-Bayes and fully Bayesian approaches to variable selection through examples, theoretical results and simulations. Considerable differences between the two approaches are found. In particular, we prove a theorem that characterizes a surprising aymptotic discrepancy between fully Bayes and empirical Bayes. This discrepancy arises from a different source than the failure to account for hyperparameter uncertainty in the empirical-Bayes estimate. Indeed, even at the extreme, when the empirical-Bayes estimate converges asymptotically to the true variable-inclusion probability, the potential for a serious difference remains.




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Estimating the rate constant from biosensor data via an adaptive variational Bayesian approach

Ye Zhang, Zhigang Yao, Patrik Forssén, Torgny Fornstedt.

Source: The Annals of Applied Statistics, Volume 13, Number 4, 2011--2042.

Abstract:
The means to obtain the rate constants of a chemical reaction is a fundamental open problem in both science and the industry. Traditional techniques for finding rate constants require either chemical modifications of the reactants or indirect measurements. The rate constant map method is a modern technique to study binding equilibrium and kinetics in chemical reactions. Finding a rate constant map from biosensor data is an ill-posed inverse problem that is usually solved by regularization. In this work, rather than finding a deterministic regularized rate constant map that does not provide uncertainty quantification of the solution, we develop an adaptive variational Bayesian approach to estimate the distribution of the rate constant map, from which some intrinsic properties of a chemical reaction can be explored, including information about rate constants. Our new approach is more realistic than the existing approaches used for biosensors and allows us to estimate the dynamics of the interactions, which are usually hidden in a deterministic approximate solution. We verify the performance of the new proposed method by numerical simulations, and compare it with the Markov chain Monte Carlo algorithm. The results illustrate that the variational method can reliably capture the posterior distribution in a computationally efficient way. Finally, the developed method is also tested on the real biosensor data (parathyroid hormone), where we provide two novel analysis tools—the thresholding contour map and the high order moment map—to estimate the number of interactions as well as their rate constants.




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On the best constant in the martingale version of Fefferman’s inequality

Adam Osękowski.

Source: Bernoulli, Volume 26, Number 3, 1912--1926.

Abstract:
Let $X=(X_{t})_{tgeq 0}in H^{1}$ and $Y=(Y_{t})_{tgeq 0}in{mathrm{BMO}} $ be arbitrary continuous-path martingales. The paper contains the proof of the inequality egin{equation*}mathbb{E}int _{0}^{infty }iglvert dlangle X,Y angle_{t}igrvert leq sqrt{2}Vert XVert _{H^{1}}Vert YVert _{mathrm{BMO}_{2}},end{equation*} and the constant $sqrt{2}$ is shown to be the best possible. The proof rests on the construction of a certain special function, enjoying appropriate size and concavity conditions.