Statement Highlights: While significant improvements have been made in resuscitation and post cardiac arrest resuscitation care, mortality remains high and is mainly attributed to widespread brain injury.Better science is needed to support the ...

Traumatic brain injury (TBI) can have lifelong and dynamic effects on health and wellbeing. Research on the longterm consequences emphasises that, for many patients, TBI should be conceptualised as a chronic health condition. Evidence suggests that functional outcomes after TBI can show improvement or deterioration up to two decades after injury, and rates of all-cause mortality remain elevated for many years. Furthermore, TBI represents a risk factor for a variety of neurological illnesses, including epilepsy, stroke, and neurodegenerative disease. With respect to neurodegeneration after TBI, post-mortem studies on the long-term neuropathology after injury have identified complex persisting and evolving abnormalities best described as polypathology, which includes chronic traumatic encephalopathy. Despite growing awareness of the lifelong consequences of TBI, substantial gaps in research exist. Improvements are therefore needed in understanding chronic pathologies and their implications for survivors of TBI, which could inform long-term health management in this sizeable patient population.

Traumatic brain injury (TBI) is a leading cause of death and disability. Older adults are more likely than younger individuals to sustain TBIs and less likely to survive them. TBI has been called the “silent epidemic,” and older adults are the “silent population” within this epidemic. This study evaluates whether indicators of preinjury health and functioning are associated with risk of incident traumatic brain injury (TBI) with loss of consciousness (LOC) and to evaluate health‐related factors associated with mortality in individuals with incident TBI.

The association of dispositional optimism with health-related factors has been well established in several clinical populations, but little is known about the role of optimism in recovery after traumatic brain injury (TBI). Given the high prevalence of cognitive complaints after TBI, the present study examined the association between optimism and cognitive functioning after TBI.

Homelessness is a global public health concern, and traumatic brain injury (TBI) could represent an underappreciated factor in the health trajectories of homeless and marginally housed individuals. We aimed to evaluate the lifetime prevalence of TBI in this population, and to summarise findings on TBI incidence and the association between TBI and health-related or functioning-related outcomes.

The national age-adjusted rate of fall-related TBI deaths increased by 17% from 2008 to 2017; rates increased significantly in 29 states and among nearly all groups, most notably persons living in noncore nonmetropolitan counties and those aged ≥75 years.

A look at how to describe clinical recovery time and factors that might impact recovery after a sports-related mild traumatic brain injury (SR-mTBI; concussion).

'It can happen to you anywhere, at any moment, and just change your world'

By turning 'Stella' into a punchline, laughter became my medicine and sharing my story became my therapy

The congressional Brain Injury Task Force, co-chaired by Reps. Bill Pascrell Jr. (D-N.J.) and Don Bacon (R-Neb.), spoke to hundreds of people gathered at the Rayburn House Office Building. One area of focus was the development of a national traumatic brain injury registry, a vital step for getting a handle on how best to manage this difficult-to-treat condition.

Managing money is complicated, especially for people with a brain injury who may have trouble remembering what they spent or creating a budget. Adam shares some tips from online banking to keeping a spending journal.

If extra time on a test or memory aids can make life easier during college, why not use them? Adam talks about moving past the "stigma" of using disability services and getting the help you need to succeed in college.

A device and method for using the device arranged to maintain anatomical alignment between a joint by creating a dynamic load around the joint to restore and maintain the anatomical alignment. The orthotic device uses a hinge to create a directed force on a tibia by maintaining misalignment of an instant center of rotation (ICoR) of the hinge at a position relative to an anatomical knee joint.

The present invention relates to muscle repair promoters for local application that contain a colony-stimulating factor (CSF) as an active ingredient. The muscle repair promoters of the present invention exhibit their effect at low doses, particularly when they are administered intramuscularly.

ENGLAND hockey star Alex Danson has revealed she is on the road to recovery after suffering a brain injury.

It can be said that ignorance is bliss, and when it came to football that was the case for our own Dr. Bob Duke. A lifelong football fan, Duke was thrown into a dilemma by a recent study done by researchers at Boston University that revealed that, “chronic traumatic encephalopathy (CTE), a progressive, degenerative brain...

On this edition of Two Guys on Your Head, Dr. Art Markman and Dr. Bob Duke talk about the psychology of moral injury.

Panic immediately set in at the sight of an injured Ellyse Perry limping from the field, but her limited role in the Australian T20 team might mean the side can cope better than expected, writes Geoff Lemon.

Perry was helped off the field after an off-balance throw in an attempted run-out.

Australia's superstar all-rounder Ellyse Perry will go under the knife and face six months out of cricket after injuring her hamstring during her team's T20 World Cup campaign.

Artist Tanya Stubbles created 22 artworks for a Chinese client six months after leaving a brain injury unit in Sydney.

Wazza the koala has left carers astounded after she was collected by a car and endured a 10km trip down a major NSW roadway, only to bolt up a tree afterwards.

One of the Top End's only female bull riders has taken on the US rodeo circuit despite suffering a serious shoulder injury just days from leaving.

Policeman-turned-lawyer David Healey's mental health was shattered by a rocket blast in Afghanistan. He now helps other traumatised cops fight for compensation.

Dark-coloured jerseys could lead to poor performance, increased rates of injury, and even jeopardise the careers of young rugby league players, researchers say.

As opportunities increase for women in contact sports, concerns about injury rates are also on the rise. But for some the health benefits outweigh the risk of injury.

Two regional Australian doctors are at the forefront of an international effort to eliminate a horrendous childbirth injury, and say they could succeed within a decade.

(United States Third Circuit) - In a class action suit against the National Football League (NFL), brought by former players who alleged that the NFL failed to inform them of and protect them from the risks of concussions in football, the District Court's judgment is affirmed where the District Court was right to certify the class and approve the settlement.

Queen guitarist Brian May injured himself while gardening at home earlier this week.

Adult On-Road Cyclist Injury in Victoria, 2008/09 to 2017/18: A Report on Ambulance Attendances, Emergency Department Presentations, Hospital Admissions and Deaths , released by Monash University

Although CEACAM1 (CC1) glycoprotein resides at the interface of immune liver injury and metabolic homeostasis, its role in orthotopic liver transplantation (OLT) remains elusive. We aimed to determine whether/how CEACAM1 signaling may affect hepatic ischemia-reperfusion injury (IRI) and OLT outcomes. In the mouse, donor liver CC1 null mutation augmented IRI-OLT (CC1-KO→WT) by enhancing ROS expression and HMGB1 translocation during cold storage, data supported by in vitro studies where hepatic flush from CC1-deficient livers enhanced macrophage activation in bone marrow–derived macrophage cultures. Although hepatic CC1 deficiency augmented cold stress–triggered ASK1/p-p38 upregulation, adjunctive ASK1 inhibition alleviated IRI and improved OLT survival by suppressing p-p38 upregulation, ROS induction, and HMGB1 translocation (CC1-KO→WT), whereas ASK1 silencing (siRNA) promoted cytoprotection in cold-stressed and damage-prone CC1-deficient hepatocyte cultures. Consistent with mouse data, CEACAM1 expression in 60 human donor liver biopsies correlated negatively with activation of the ASK1/p-p38 axis, whereas low CC1 levels associated with increased ROS and HMGB1 translocation, enhanced innate and adaptive immune responses, and inferior early OLT function. Notably, reduced donor liver CEACAM1 expression was identified as one of the independent predictors for early allograft dysfunction (EAD) in human OLT patients. Thus, as a checkpoint regulator of IR stress and sterile inflammation, CEACAM1 may be considered as a denominator of donor hepatic tissue quality, and a target for therapeutic modulation in OLT recipients.

I got a job with a law firm, helping build their website, re-working their intranet site, editing videos, creating presentations for trial and other techy stuff! It is one of the largest firms in Sacramento, with about a hundred employees and almost thirty lawyers.

The Celtics outlasted the Clippers, 141-133, in two overtimes in a result that, for Los Angeles, was overshadowed by a third injury to star forward Paul George's left hamstring in the last five weeks.

Outfielder Brandon Marsh, the Angels' No. 2 prospect, will be out several weeks with a strained left elbow. He hurt it while attempting a diving catch.

Jimmy Nelson blew out his pitching shoulder in a baserunning mishap in 2017. Now the former Brewers starter is attempting a comeback with the Dodgers.

From the archives: How Ed O'Bannon didn't let a torn knee ligament stop him from propelling UCLA to its 11th NCAA title win in 1995.

Generation Xers accounted for half of all the people that died in smoking related fires and a third of injuries, according to new data from London Fire Brigade.

It was the longest match in the history of the Buenos Aires tournament.

Leeds boss Marcelo Bielsa and his Elland Road staff are worried that they won't see the best of striker Jean-Kevin Augustin before the end of the season due to his numerous injury problems, as the promotion race hots up in the Championship.

Steven Gerrard believes Ryan Kent will get even better for Rangers as he’s not even fully fit yet.

Leeds manager Marcelo Bielsa has claimed that he's hopeful that both Kiko Casilla and Kalvin Phillips will be fit to play against Middlesbrough on Wednesday night. Casilla had taken a kick in the hand against Reading, while Phillips limped off in the 37th minute during the Championship clash.

Leeds face Middlesbrough in the Championship on Wednesday evening, with Marcelo Bielsa hoping to continue the Whites' good form after back-to-back wins. Express Sport brings you the latest team news and injury updates, with concerns over the inclusion of Kalvin Phillips and Kiko Casilla in the manager's starting XI.

Ryan Christie will head to Celtic much earlier than expected after being ruled out for at least a month with a knee injury.

The Pacers didn't have their starting point guard for the last three games before the NBA went on hiatus, but he's able to play if/when it restarts.

A Bargersville police officer and the driver of an SUV were taken to the hospital with minor injuries after a vehicle crash Friday.

The Pacers didn't have their starting point guard for the last three games before the NBA went on hiatus, but he's able to play if/when it restarts.