RT @mrbromwich: I have been in and around DOJ since 1983. I have never seen a case dropped after someone has pled guilty and the underlying facts demonstrate beyond any shadow of a doubt he is guilty. This is simply a pardon by another name. A black day in DOJ history.

(California Court of Appeal) - Reversing the trial court's denial of a writ petition and declaratory and injunctive relief in the case of a city project because the trial court's dismantling of agreements entered into by an earlier administration and agency unconstitutionally impaired a private developer's contractual rights.

Jim Frey, who managed the Kansas City Royals to the 1980 AL pennant and the Chicago Cubs to within one win of the 1984 World Series, has died. He was 88.

Selected Route From Rochester To Brighton Scheduled For July, In Support Of Music Heals

Their first meeting literally knocked them off...and it took them twelve hours to finally kiss. **Harry never went to Hogwarts-AU**

Page 88 of the third chapter of Starfighter.

Page 87 + 88 of the fourth chapter of Starfighter.

Page 88 of the fifth chapter of Starfighter.

On the podcast today:

- News Updates: Wizard Unite username reservation

- News Update: WB concerned about Depp’s participation in the films

- Can they recast Jonny Depp at this point?

- Horcruxes: Voldemort and Grindelwald

- Post Production Interview: Changes to the Wizarding World

- Rules of the Potterverse: Can you change McGonagall’s canon?

- International Travel in Crimes of Grindelwald

This episode was produced by Adam Molina and production assisted by Kylie Madden; and named by our patron, Adam Davis! Thank you, Adam!

The early morning dawn light was streaming in through the window . The time seemed irrelevant . It was still not quite light enough to rise . Looking at my watch I hoped the green luminous fingers would give me a clue to the time . It felt like 5am. The fi

In 1945, when US president Franklin D. Roosevelt died—just 82 days into his fourth term—Truman, his vice president, assumed the office. Presiding over the end of World War II and the transition to peacetime, he made unexpectedly bold decisions. He dropped the first atomic bombs on Japan, proposed the "Truman Doctrine" of Communist containment, authorized the Berlin Airlift, and initiated US involvement in the Korean War. For most of his second term, Truman did not live in the White House. Why?

Worden performed the first deep-space spacewalk — nearly 200,000 miles from Earth

Ferrari's 488 Pista, which replaces the 458 Speciale, is driven by the most powerful V8 engine Ferrari has ever put in a road car.

NASA’s Goddard Institute for Space Studies (GISS) monitors global surface temperatures on an ongoing basis. Their analysis shows temperatures around the globe in 2011 compared to the average global temperature from the mid-20th century. The comparison shows how Earth continues to experience warmer temperatures than several decades ago.

Global temperatures have warmed significantly since 1880, the beginning of what scientists call the “modern record.” At this time, the coverage provided by weather stations allowed for essentially global temperature data. As greenhouse gas emissions from energy production, industry and vehicles have increased, temperatures have climbed, most notably since the late 1970s. In this animation of temperature data from 1880-2011, reds indicate temperatures higher than the average during a baseline period of 1951-1980, while blues indicate lower temperatures than the baseline average.

Click on the image to see the video:

Read full article: Global Temperature Anomaly, 1880 - 2011

General Motors' first-quarter net income fell 88 per cent, but it still managed to make US$247 million despite the arrival of the global coronavirus pandemic.

Hindistan da nükleer denizaltısı olan ülkeler arasına katıldı. Hindistan böylece, Amerika Birleşik Devletleri, Rusya, Fransa, İngiltere ve Çin'in ardından nükleer denizaltısı olan altıncı ülke oldu.

İnsanoğlunun Ay'a ayak basışının 40. yıl dönümü ABD'de bir dizi etkinlikle kutlanıyor. Ay'a ayak basan ilk insan olan Neil Armstrong, 'Bir insan için küçük, insanlık için dev bir adım' demişti.

İngiltere'de ekonominin yılın 2. çeyreğinde de binde 8 küçülmesi, resesyondan çabuk çıkılabileceğine yönelik umutları azalttı. Almanya'nın ise resesyondan çıkma yolunda olduğu belirtiliyor.

İngiliz petrol devi BP, yılın 2. çeyreğinde kârının, geçen yılın aynı dönemine kıyasla yüzde 53 azaldığını duyurdu. BP, bu duruma gerekçe olarak, petrol fiyatlarının düşük olmasını gösterdi.

ABD Savunma Bakanı Robert Gates, sürpriz Irak ziyareti sırasında ABD birliklerinin muharip görevi geçen ay Irak güçlerine bırakması sonrası ülkede güvenlik koşullarındaki düzelmeyi övdü.

Yunanistan güvenlik güçlerinin, gözaltına aldıkları sığınmacıları Türkiye sınırına doğru sürdükleri ve Meriç nehrinden Türkiye'ye geçmeye zorladıkları iddia edildi.

İngiltere'de insan hakları eylemcileri, CIA'in 'olağanüstü nakil' olarak bilinen uygulamasında İngiliz hükümetinin oynadığı iddia edilen rolün açıklanması için mahkemeye gitti.

Guardian yazarı Simon Tisdall, Türkiye'deki Kürt açılımı tartışmalarını ele aldığı yazısında, Atatürk'ün mirasına Başbakan Erdoğan'ın en büyük darbeyi vurmak üzere olabileceğini öne sürüyor.

Dünya Gündemi'ni Çarşamba ve Cuma günleri 10:30'da, Cumartesi günleri 20:30'da NTV'de izleyebilirsiniz.

Orta Doğu'da barış sürecini canlandırmak için diplomasi atağı başlatan ABD son olarak da Başkan Barack Obama'nın ulusal güvenlik danışmanı James Jones'u bölgeye gönderdi.

Travel Photography tips

The Amateur Traveler talks to Jason and Janie about their trip to Bavaria and Southern Germany. Jason and Janie had perviously been on the Amateur Traveler on Travel to Barbados - Episode 109. The talk about visiting the Black Forest with its wineries, Geramany’s tallest waterfall and the world’s largest cuckoo clock. They also visited the walled city of Rothenburg ob der Tauber. Rothenburg (which may have been spared the ravages of the 30 years war by a hard drinking mayor) is the home to a wonderful Christmas market as well as a Christmas museum. The Rothenburg Nightwatchman’s tour is also something you should try. Jason and Jamie also went to Nurenburg with its wonderful market place and saw “Mad” King Ludwig’s castle Neuschwanstein. The finished the trip in the home of very large beer steins at Munich. In Munich they enjoyed the glockenspiel, the toy museum and some of the wonderful old churches.

The Amateur Traveler talks to Andy Steves about Rome, Italy. Andy talks about practical issues like how to get into and around Rome, how to connect to the Rome of the Roman Empire (the Coloseum, Forum and Circus Maximus, Basilica of Maxentius and Constantine, Pantheon). He also talks about a tour of the Sistine Chapel without all the crowds and not easy to do. Andy also gives us his favorite spots from Renaissance Rome like the Galleria Borghese and how to get under Saint Peter's to the excavation of older Saint Peter's. Follow Andy to places where you can meet modern Romans on your evening passeggiata to Campo di Fiori, Piazza Navona, Trevi Fountain and the Spanish Steps. And then meet one of his favorite Romans who runs a hang out for students near the Pantheon.

Andy is the son of travel author and tour guide operator Rick Steves and is following in his father's footsteps running weekend tours for students studying in Europe.

Hear about travel to the Island of Shikoku, Japan as the Amateur Traveler talks to Dan from Chicago about his recent trip back to the island. Dan also worked teaching English on Shikoku in the city of Imabari. Shikoku is the 4th largest of the islands in Japan and just across the from Hiroshima. Shikoku is mountainous, more traditional and more rural than the areas of Japan more tourists know.

Hear about travel to Northern Romania as the Amateur Traveler talks to Ralph Velasco of photoenrichment.com about the region that he visited leading a recent photo tour.

We talk about the regions of Maramureş and Bukovina, north of Transylvania.

Hear about travel to New Caledonia as the Amateur Traveler talks to CJ Johnson from the MOVIELAND ABC Radio Show and Podcast about his recent trip to this part of France in the South Pacific.

Hear about travel to the Mississippi Gulf Coast as the Amateur Traveler talks to Charles McCool from McCoolTravel.com about this tasty area with great beaches.

How Do Home Sales Affect the Economy in Your State?

Although a robust inflammatory response is needed to combat infection, this response must ultimately be terminated to prevent chronic inflammation. One mechanism that terminates inflammatory signaling is the production of alternative mRNA splice forms in the Toll-like receptor (TLR) signaling pathway. Whereas most genes in the TLR pathway encode positive mediators of inflammatory signaling, several, including that encoding the MyD88 signaling adaptor, also produce alternative spliced mRNA isoforms that encode dominant-negative inhibitors of the response. Production of these negatively acting alternatively spliced isoforms is induced by stimulation with the TLR4 agonist lipopolysaccharide (LPS); thus, this alternative pre-mRNA splicing represents a negative feedback loop that terminates TLR signaling and prevents chronic inflammation. In the current study, we investigated the mechanisms regulating the LPS-induced alternative pre-mRNA splicing of the MyD88 transcript in murine macrophages. We found that 1) the induction of the alternatively spliced MyD88 form is due to alternative pre-mRNA splicing and not caused by another RNA regulatory mechanism, 2) MyD88 splicing is regulated by both the MyD88- and TRIF-dependent arms of the TLR signaling pathway, 3) MyD88 splicing is regulated by the NF-κB transcription factor, and 4) NF-κB likely regulates MyD88 alternative pre-mRNA splicing per se rather than regulating splicing indirectly by altering MyD88 transcription. We conclude that alternative splicing of MyD88 may provide a sensitive mechanism that ensures robust termination of inflammation for tissue repair and restoration of normal tissue homeostasis once an infection is controlled.