Titanium dioxide which includes particles having a large major-axis length in a large proportion and comprises columnar particles having a satisfactory particle size distribution. A titanium compound, an alkali metal compound, and an oxyphosphorus compound are heated/fired in the presence of titanium dioxide nucleus crystals having an aspect ratio of 2 or higher to grow the titanium dioxide nucleus crystals. Subsequently, a titanium compound, an alkali metal compound, and an oxyphosphorus compound are further added and heated/fired in the presence of the grown titanium dioxide nucleus crystals. Thus, titanium dioxide is produced which comprises columnar particles having a weight-average major-axis length of 7.0-15.0 μm and in which particles having a major-axis length of 10 μm or longer account for 15 wt. % or more of all the particles.

Tens of Thousands of California Inmates at Risk of COVID-19 Infection Jose Amendariz was on one of his frequent trips to the nurse’s station in Orange County’s largest jail when deputies hauled in a man in a mask. Of all the inmates inside the jail, the 29-year-old Armendariz needs the most care: insulin shots for Type I diabetes, pills for hypertension, asthma inhaler puffs for his ravaged respiratory system.…

A suspension system (20) is described for vehicle with a frame, comprising an element (R, 12) propulsive by rolling on the ground; two units (12a, 12b) adapted to impart a torque to the propulsive element that are controllable independently of one another, where the two units are movable relative to the propulsive element independently from one another and rigidly connectable to the frame at one same point (P). By moving one or each unit relative to the propulsive element the distance between the latter and said point is made to vary.

A displacement sensor having a rectangular shaped elastic member. A piezoelectric element is attached to a first main face of the elastic member. The piezoelectric element has a rectangular-shaped piezoelectric sheet and electrodes on both main faces of the piezoelectric sheet. The piezoelectric sheet is made of poly-L-lactic acid and is at least uniaxially-stretched. The piezoelectric element is attached so that the uniaxial-stretching direction of the piezoelectric sheet is 45° relative to a long-side direction of the elastic member. When the elastic member is bent along the long-side direction, the piezoelectric sheet is stretched along the long-side direction, and the piezoelectric element generates voltage of predetermined level.

An object is to provide an interior permanent magnet rotor unit that allows possible demagnetization to be suppressed regardless of a material for a portion of a permanent magnet, which is positioned on an outward side in a radial direction of a core. A core is a laminate of first thin-plate-like members and second thin-plate-like members. The first thin-plate-like members and the second thin-plate-like members have first insertion slots and second insertion slots each of which is filled with a permanent magnet. In the first thin-plate-like members, a separating portion is formed at an end of each of the first insertion slots or the second insertion slots, which end is located on an outward side of the insertion slot in a radial direction, to form a slit in the corresponding permanent magnet.

Raw material magnet is milled to magnet powder, and the magnet powder thus milled is mixed with a binder to form a compound 12. Then, the compound 12 thus formed is molded to a green sheet 14 having a sheet shape. Thereafter, a magnetic field orientation is carried out by applying a magnetic field to the green sheet 14 thus molded, and then, the green sheet 14 having been subjected to the magnetic field orientation is shaped to a product shape by deforming thereof. Thereafter, the permanent magnet 1 is produced by sintering thereof. The permanent magnet 1 has a ring shape, and is constituted such that an axis of easy magnetization may be orientated at a slant so as to converge in a direction along a converging axis P which is set to a radius direction as well as to a center direction of the ring shape.

A single phase permanent magnet motor includes a stator and a rotor. The stator includes a stator core with windings. The stator core includes a yoke and claw-poles. Each claw-pole forms an arc pole face which is an involute curved face. All arc pole faces cooperatively define a space for receiving the rotor. A gradually changing uneven air gap is defined between the arc pole faces and the rotor. When the motor powers off and stops, the pole axis of the rotor is offset from the central axis of the claw-poles by a certain angle to avoid the rotor to stop at a dead point position, thus facilitating next startup of the motor.

An interior sock is fabricated of a flexible elastic polymer. The interior sock has a cylindrical closed toe section, a cylindrical open ankle section and an intermediate heel section. The heel section is provided between the toe and ankle sections. An exterior sock is fabricated of a knitted blend of cotton and a minor portion of an elastic. The exterior sock has a cylindrical closed toe section, a cylindrical open ankle section and an intermediate heel section. The heel section is provided between the toe and ankle sections. A quantity of therapeutic fluid is located within the interior sock. The therapeutic fluid is in contact with a foot of a user. The interior sock provides support for the therapeutic fluid. The exterior sock provides pressure and warmth to the interior sock and the therapeutic fluid.

A fabric assembly attachable to the front side of a men's underwear and a men's underwear having such a fabric assembly are described. The fabric assembly has layers of fabrics having linear slots perpendicular to each other so that the wearer can take his genital organ out through the intersection of the linear slots. The peripheries of the fabric layers are elastically stitched together to make a fabric assembly. The fabric layers have sufficient rigidity such that the linear slots do not open under the pressure of the genital organ, unless the wearer uses his hands to open the slots. The fabric assembly may also have a flap on the inside or outside of the fabric layers. One or two sides of the flap may be attached to the men's underwear and the other sides may not be attached to permit easy opening of the flap by hand.

A personal protection device for protecting a user is described. The personal protection device can have an inflatable member having an internal chamber that can be inflated or deflated according to predetermined conditions.

An article of manufacture for stretchable night visibility bands for people and animals with a inner band consisting of a primarily stretchable material, an outer band consisting of a night visibility material, a way to attach the inner band to the outer band, a means to interchange said inner bands and said outer bands and a way to close the inner band around an object. A preferred embodiment includes further an outer band made of a night visibility material fabricated of least one of the following: a reflective, a florescent or a glow in the dark material and backed with a material such as VELCRO that attaches to the inner band, A preferred embodiment includes the element of inner band consisting of a stretchable material with a looped surface such as Velstretch™.

An orthopedic component for use in orthopedic device includes a rigid frame and a flexible subshell connected to and extending flexibly outwardly from the rigid frame. The subshell may have a shell body and a perimeter edge portion defining a lip extending outwardly from a surface of a shell body and defining a clearance between the shell body and the lip. The subshell may include a plurality of slots and ventilated padding is used in combination with the slots. A tightenable fastener may be adjustably secured to the rigid frame and extend through an opening on the subshell, wherein the first side portion of the subshell is adjustable in location relative to the rigid frame.

Drum pedal assemblies are disclosed which can include one or more adjustment features. Adjustment features which can be included in embodiments of the invention can include spring tension adjustment features, pedal incline adjustment features, lever length adjustment features, beater stem angle adjustment features, chain path adjustment features, operable chain length adjustment features, and chain connection point position adjustment features.

The invention is a sound modification device used for a percussion instrument. It is comprised of a rigid clip that is spring-based to a closed position and an integrated dampening material, leather or plastic etc., that comes in contact with the vibrating surface. Once the clip is pulled apart it can be released to firmly attach over the hoop of any drum. The musician can choose the size or material of the dampening component to eliminate unwanted ring and or change the resonant note of the drum. The thickness of the dampening component can also be chosen by the drummer to increase or decrease the dampening characteristics.

A music composition, editing, and playback system and method provides a user interface design based on geometric interpretation of music theory replacing traditional modern music notation with geometric shapes including chords represented by polygons that are colored with colors or hues.

This disclosure generally relates to a guitar pedal board configured to maintain an open position and a closed position. In one embodiment, a surface of a guitar pedal board is configured to receive and hold guitar pedals on a surface that may be inclined relative to a surface on which the guitar pedal board rests. In another embodiment, the guitar pedal board includes one or more retainer stands that hold the guitar pedal board in a closed position. In another embodiment, the guitar pedal board includes a support member that holds the guitar pedal board in an open position. In another embodiment, a first guitar pedal board includes an attachment foot configured to attach one or more guitar pedal boards to the first guitar pedal board.

A method for processing a music performance, the method comprising the steps of: receiving a first media signal from a media source; analysing the first media signal to extract any media signal characteristics; creating a reference media signal by suppressing at-least a predominant sound source of the first media signal; reproducing the reference media signal while receiving a users media signal from an input device to generate a second media signal; analysing the second media signal to extract any media signal characteristics; processing the characteristics of the second media signal in isolation or in combination with the characteristics of the first media signal; and generating feedback for the music performance based upon the processed media signals.

A percussion device includes (1) a platform portion composed of a first material having an exposed striking portion composed of a second material different from the first material; (2) a base portion separated from, and substantially parallel to, the platform portion by a predetermined distance; (3) at least one unitary sidewall portion positioned between the platform portion and the base portion at respective opposing edges of the platform portion and the base portion; and (4) a non-flexible surface below, and in contact with, at least a portion of the exposed striking portion.

The specification discloses a novel drumstick configuration with an enhanced grip and performance characteristics. Included in the drumstick are a plurality of preferably continuous circumferential longitudinally spaced-apart grooves disposed in an outer surface of an elongate body portion. The grooves each contain a grip-enhancing material which has an upper surface disposed slightly above the outer surface of the body portion to enhance the grip and general performance characteristics of the drumstick.

A suspended ceiling system for a building structure includes a plurality of parallel struts for supporting a plurality of parallel vanes suspended from the struts in perpendicular relationship thereto. The vanes can be suspended in downwardly spaced relationship to the struts or in contiguous relationship therewith and occur in different forms including illuminated vanes, adjustable vanes and the like.

An incremental forming machine binder is provided that has a blank holding opening that may be subdivided into smaller blank holding openings. The opening is subdivided by one or more clamping modules that are connected by connecting modules to each other and the frame. Clamps are attached to the clamping modules to clamp blanks in the blank holding openings. Multiple blanks may be secured to the binder for incremental forming.

An ambulatory surgical center can include a hybrid operating room. The hybrid operating room can include at least four lead-shielded walls, a floor, and a ceiling. The ambulatory surgical center can also include an imaging device disposed in a central area of the hybrid operating room. The ambulatory surgical center can further include an operating table disposed in the central area of the hybrid operating room. The ambulatory surgical center can additionally include a power room adjacent to the operating room. The power room can include a power supply for the imaging device. The ambulatory surgical center can also include a conduit from the power room to the imaging device configured to deliver power to the imaging device. The ambulatory surgical center can further include an emergency power source for the imaging device configured to permit continuity of surgery in the hybrid operating room during a power outage.

An intelligent bionic expectoration system and a three-way device thereof. The intelligent bionic expectoration system includes a negative pressure suction module, a central processing module, a patient interface unit and a respiratory muscle synchronous motion module. The central processing module controls two valves to open or close, closing one valve while opening another valve, and controls the respiratory muscle synchronous motion module. The patient interface unit is connected to the positive pressure ventilation module and the negative pressure suction module, allowing positive or negative pressure airflow to flow by, depending on which valve is open, so as to allow airflow to flow in or out of the lung. The respiratory muscle synchronous motion module can employ nerve stimulation and mechanical pushing, and acts synchronously as the airflow moves, thereby simulating human coughing and achieves bionic expectoration.

An example method for detecting respiratory disturbances experienced by a subject can include receiving an airflow signal and at least one of an acoustic or vibration signal, where the airflow, acoustic, and/or vibration signals are associated with the subjects breathing. At least one feature can be extracted from the airflow signal and at least one feature can be extracted from at least one of the acoustic or vibration signal. Based on the extracted features, at least one respiratory disturbance can be detected. The respiratory disturbance can be flow limited breath or inspiratory flow limitation (“IFL”).

Certain embodiments are directed to a specimen retrieval device having a high friction inner lining for reducing specimen deformation during removal. Certain embodiments are directed to a device that facilitates isolation and removal of specimens during minimally invasive surgery. In certain aspects the device is configured to disperse pulling tension over a larger area reducing the likelihood of specimen tearing during removal. The device enables quicker removal through a smaller hole or opening in the body wall.

A method and a control program for operating an anesthesia apparatus, as well as an anesthesia apparatus (12), which operates according to the method are provided. The anesthesia apparatus includes a breathing gas feed unit (22) intended for displacing a breathing gas volume in a breathing circuit (10). A piston (23) brings about the displacement of the breathing gas. Switching over between a first mode of operation and a second mode of operation during the return of the piston (23) allows for a presetting of a corresponding piston return velocity. The piston return velocity depends on a volume flow in an exhalation branch (34) of the breathing circuit (10) in the first mode of operation. The piston return velocity depends on a minimally necessary piston return velocity in the second mode of operation.

A device comprising: a receive antenna configured to receive a first radio-frequency (RF) signal having a first center frequency; a first transmit antenna configured to transmit a second RF signal having a second center frequency that is a harmonic of the first center frequency; a second transmit antenna configured to transmit a third RF signal having a third center frequency that is a harmonic of the first center frequency and is different from the second center frequency; first circuitry, coupled to the receive antenna and to the first transmit antenna, configured to generate the second RF signal using the first RF signal and provide it to the first transmit antenna for transmission; and second circuitry, coupled to the receive antenna and to the second transmit antenna, configured to generate the third RF signal using the first RF signal and provide it to the second transmit antenna for transmission.

Antenna system for a georadar, comprising two plate like antenna devices, where said two antenna devices comprise at least one sender antenna (1) and at least one receiver antenna (2), respectively, as the antennas (1,2) in each antenna device comprise monopoles formed by applying to metal surfaces an electrically insulating plate base (3) located on the underside of a layer of radar absorbing material (4), where the top side of the material layer is covered by a metallic ground plane (5). The antenna device is also arranged to lay against the ground (10). A layer of radar absorbent material (4) is arranged on the top side of the ground planes (5), and the ground planes (5) are not connected electrically to each other.

An antenna system including: a metal base plate; an antenna element arranged on and extending away from the front side of the base plate; a circuit board including a ground plane, adjacent to, and in thermal contact with the base plate; a plurality of electrical components on the circuit board including a power amplifier and an I/O connector; a metal support plate separated from, parallel to, and facing the base plate, with the circuit board located between the base and support plates; a plurality of thermally conductive standoffs thermally connecting the base plate to the support plate; and a master board including an I/O connector mating with the I/O connector on the circuit board and electrically connecting the circuit board to the master board, the master board located between the circuit board and the support plate and including signal paths for routing signals to the circuit board.

A tracking antenna system for discrete radio frequency spectrums includes a reflector, a pedestal supporting the reflector, a radome assembly enclosing both, a first feed for gathering radio waves within a first of discrete RF spectrums that is removably disposed in front of the reflector at the focal point, a first RF module operably connected to the first feed for converting the first gathered radio waves to first electronic signals, a feed mount for removably supporting the first feed and configured to removably support a second feed for gathering radio waves within a second of discrete RF spectrums, and a module mount for removably supporting the first RF module and configured to removably support a second RF module for converting the second radio waves to second electronic signals. A method of using the tracking antenna system adaptable for discrete radio frequency spectrums is also disclosed.

A polymerizable liquid crystal compound represented by Chemical Formula 1: wherein in Chemical Formula 1, groups and variables are the same as defined in the detailed description.

A compensation film includes an elongation film having an elongation rate of greater than or equal to about 200% in a uniaxial direction and having a surface energy of about 40 mJ/m2 to about 65 mJ/m2 and a liquid crystal layer disposed on one side of the elongation film and including liquid crystals.

For coating substrates (S) having along their surfaces to be coated high aspect ratio vias, a sputtering system has a sputtering source arrangement, which includes a first DC pulse operated magnetron sub-source (1203) and a second frame-shaped magnetron sub-source (1213) which latter is arranged, in the system, between the substrate (S) and the first magnetron sub-source (1203). The second magnetron sub-source (1213) may be operated in DC, pulsed DC, thereby also HIPIMS mode. The first magnetron sub-source (1203) is advantageously also operated in HIPIMS mode. The substrate (S) is biased by an Rf power source (1253).

A magnetically enhanced low temperature high density plasma chemical vapor deposition (LT-HDP-CVD) source has a hollow cathode target and an anode, which form a gap. A cathode target magnet assembly forms magnetic field lines substantially perpendicular to the cathode surface. A gap magnet assembly forms a magnetic field in the gap that is coupled with the cathode target magnetic field. The magnetic field lines cross the pole piece electrode positioned in the gap. The pole piece is isolated from ground and can be connected to a voltage power supply. The pole piece can have negative, positive, floating, or RF electrical potentials. By controlling the duration, value, and sign of the electric potential on the pole piece, plasma ionization can be controlled. Feed gas flows through the gap between the hollow cathode and anode. The cathode can be connected to a pulse power or RF power supply, or cathode can be connected to both power supplies. The cathode target and substrate can be inductively grounded.

The concentration measurement method includes: introducing a predetermined amount of the biological sample into the capillary; measuring a temperature of the biological sample by applying a first voltage to the electrode unit when the temperature of the biological sample is measured, the first voltage allowing the temperature measurement to be less affected by increase and reduction in an amount of the analyte contained in the biological sample; measuring the concentration of the analyte contained in the biological sample by applying a second voltage to the electrode unit; measuring an environmental temperature in a surrounding of the biological sample; and correcting the concentration of the measured analyte based on the measured temperature of the biological sample and the measured environmental temperature.

In an ozone generating system which performs intermittent operation, that is, an operation in an ozone generating operation period in which ozone is generated by discharging gas including oxygen at a discharge electrode part and an operation in an ozone generating operation standby period in which ozone is not generated by stopping discharge are alternately repeated, a gas circulating device which circulates gas in the ozone generating apparatus and removes at least nitric acid from the gas which is circulated is connected to the ozone generating apparatus.

An assembly is provided for interfacing with a microfluidic chip having at least one microscopic channel configured to receive a liquid sample for analysis. The assembly includes a chip carrier, an electronics module, an optical module, and a mechanical module. The chip carrier includes a base and a cover defining a cavity to receive the microfluidic chip. The electronics module includes a signal generator which applies at least one electrokinetic signal electrode(s) of the chip. The optical module includes an excitation radiation source which causes excitation radiation to impinge on the sample, and an emission radiation detector which detects radiation emitted from the sample. The mechanical module includes a chip-carrier receiving structure, relatable with respect to the optical module for focus and at least one degree of translational freedom.

In one example embodiment, a system for treating a tissue site is disclosed comprising a dressing adapted to contact the tissue site and provide a fluid seal between a therapeutic environment and a local external environment, and a solution source fluidly coupled to the dressing and adapted to deliver an antimicrobial solution comprising a peroxy α-keto carboxylic acid, such as peroxy pyruvic acid, to the tissue interface. The system may further comprise a negative-pressure source fluidly coupled to the dressing and adapted to provide negative pressure to the therapeutic environment after delivery of the antimicrobial fluid to the therapeutic environment. In another example embodiment, a method for treating a tissue site is disclosed comprising positioning a tissue interface to contact the tissue site, covering the tissue interface and the tissue site with a drape to provide a fluid seal between the therapeutic environment and the local external environment, and delivering an antimicrobial solution comprising peroxy α-keto carboxylic acid to the therapeutic environment before providing negative pressure to the therapeutic environment.

A renal failure blood therapy system includes a renal failure blood therapy machine, concentration levels for each of a plurality of solutes removed from a patient's blood at each of the multiple times, a display device configured to display for selection at least one removed blood solute from the plurality of removed blood solutes, and a device programmed to (i) estimate at least one renal failure blood therapy patient parameter using the determined concentration levels for the at least one selected removed blood solute, (ii) determine a plurality of acceptable renal failure blood therapy treatments that meet a predetermined removed blood solute clearance for the at least one selected removed blood solute using the at least one renal failure blood therapy patient parameter, and (iii) enable selection of at least one of the plurality of acceptable renal failure blood therapy treatments for operation at the renal failure blood therapy machine.

An automated peritoneal dialysis system provides various features including prescription-driven dialysis fluid preparation, an integrated disposable fluid circuit, and sensor capabilities that allow accurate filing and draining control with high safety margins. Features include a peritoneal fluid circuit with a pressure sensor at either end and methods and devices for using the pressure signals. Other features and embodiments are disclosed.

An infusion pump system providing therapy to a patient in a closed-loop or semi-closed loop mode can safely automatically revert to open-loop therapy. The system stores a default open-loop basal rate profile in memory. The system also continually tracks the insulin on board for the patient over a plurality of closed-loop therapy intervals. When an error or event occurs requiring reversion to open-loop therapy, the system automatically provides therapy according to the open-loop basal rate profile and the tracked insulin on board amount.

The invention relates to an arrangement for determining a position (x) of a stopper relative to a container in a drug delivery device, comprising an acoustic source configured to emit an acoustic signal and an acoustic sensor configured to detect an acoustic signal, a processing unit for controlling the acoustic source and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper. Furthermore, the invention relates to a method for determining a position (x) of a stopper relative to a container in a drug delivery device, the method comprising the steps of emitting an acoustic signal from an acoustic source, detecting an acoustic signal caused by the emitted acoustic signal by means of an acoustic sensor, and processing the detected acoustic signal for determining characteristics of the acoustic signal correlated with the position (x) of the stopper by means of a processing unit.

A needle tip for an injection device includes a body having a front portion, a back portion configured to be removably connected to the pre-loaded injection device, and a wall separating the front and back portions. A hollow needle has a first piercing portion projecting back from the separating wall and a second piercing portion projecting forward from the separating wall. A safety shield that is axially movable relative to the body at least between an initial position, a retracted position, and a post use locking position. This Abstract is not intended to define the invention disclosed in the specification, nor intended to limit the scope of the invention in any way.

To enable a user to readily determine the gauge of the needle of a needle assembly that has a base and a needle protective housing pivotably attached thereto, the needle assembly is injection molded from a color coded molding material which color was preassigned to correspond to the gauge of the needle. As a result, both the base and the protective housing of the needle assembly have—the same specific color, and reflect or provide an indication of the given gauge of the needle. The needle sheath that covers the needle prior to use may be made of a plastics material that may be clear, or have the same or a different color than that of the needle assembly. The gauge of the needle of a fixed needle syringe could also be ascertained by its color coded needle protective housing. Color coded markings that correspond to the gauge of the needle may also be printed onto the syringe barrel of the fixed needle syringe.

A drug delivery device is provided herein, the device including a reservoir for containing a medicament. The medicament includes a suspension of solids in a liquid carrier. The device also includes a needle having a distal end for injection into a patient, a proximal end in communication with the reservoir, and a lumen extending between the distal and proximal ends. A path is defined from the reservoir to the distal end of the needle through the lumen, the path having an inner diameter that decreases in a proximal to distal direction along at least a portion thereof. Advantageously, with the subject invention, a flow path may be defined which provides a more gradual transition in diameter from the reservoir to a distal tip of the needle. In this manner, changes in velocity of the suspension may be less abrupt than in the prior art, thus better maintaining solid particles in the suspension.

Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible. An automated, pre-programmable transdermal administration system is used to provide pulsed doses of medications, pharmaceuticals, hormones, neuropeptides, anorexigens, pro-drugs, stimulants, nutraceuticals, phytochemicals, phytonutrients, enzymes, antioxidants, essential oils, fatty acids, minerals, vitamins, amino acids, coenzymes, or other physiological active ingredient or precursor. The system can utilize a pump, pressurized reservoir, a system for removing depleted carrier solution, or other modulated dispensing actuator, in conjunction with porous membranes or micro-fabricated structures.

The present invention relates, inter alia, to dermal systems comprising at least one light source and at least one pharmaceutically and/or cosmetically active ingredient. The dermal systems can be employed in order to enhance the penetration and action of the pharmaceutically and/or cosmetically active ingredient.

A wheel speed sensor for a motor vehicle can be supplied with an operating voltage by a control device. The control device has a load resistance with a load resistance value. An operating voltage can be at a voltage input by the control device. An electrical circuit is designed to determine a turn-on or a turn-off voltage value according to the load resistance value. An operation control is designed to transfer the wheel speed sensor into a normal operation using the operating voltage, when the turn-on voltage value is exceeded, and to transfer the wheel speed sensor into an emergency operation using the operating voltage, when a turn-off voltage value is not met. In emergency operation only a low constant signal level is emitted.

A sensored electrical jumper comprises a conductor having a first end and a second end, the first end including a first connection interface and the second end including a second connection interface, a sensor section including at least one sensor disposed over the conductor between the first and second ends, the sensor section sensing at least one of current and voltage of the conductor, and a sensor output conduit extending from the sensor and oriented substantially perpendicular to the conductor axis to protect at least one sensor output wire from leakage current or other potential electrical damage.

A universal, modular, temperature controlled MRI phantom for calibration and validation for anisotropic and isotropic imaging comprises an outer insulating shell configured to be received within an MRI chamber; an inner shell received within the outer insulating shell; a fluid conduits adjacent the inner shell for receiving temperature controlling fluid or gas cycling there-through; and a series of stacked layers of frames containing test points for the MRI phantom, each layer including at least one fiducial and including at least some anisotropic imaging test points in at least one frame and at least one isotropic imaging test point in at least one frame. The anisotropic imaging comprises hollow tubular textile fibers, wherein each hollow tubular fiber has an outer diameter of less than 50 microns and an inner diameter of less than 20 microns, wherein at least some hollow tubular fibers are filled with a fluid.