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Nucleation seed size determines amyloid clearance and establishes a barrier to prion appearance in yeast




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100 years of influenza research seen through the lens of Covid-19




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Seeking for Faculty Positions at University of Shanghai for Science and Technology

About us
University of Shanghai for Science and Technology (USST) emerged from the University of Shanghai founded in 1906 and the German Medical and Engineering School set up in 1907. Carrying on its motto of “Integrity, Righteousness, Diligence, Love, Pondering, Learning, Aspiration, Ambition”, USST aims to cultivate students with knowledge, ambitions, as well as socialist core values. Adhering to the strategy of “developing in partnership with outstanding faculty”, the university now has 16…




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Seeking for Multiple Faculty Positions in Capital Normal University (CNU)

About CNU
Capital Normal University (CNU) was founded in 1954. Being a national “Double-First Class” university and “Province-Ministry Co-sponsored” (Beijing and the Education Ministry) university, CNU has extensively broad disciplines including literature, sciences, engineering, management, law, education, foreign languages and arts. For over 60 years, CNU has cultivated more than 200 thousand graduates specializing in various fields. Currently, CNU is an important talent training base of Be…




see

Seeking for Faculty Positions at University of Shanghai for Science and Technology

About us
University of Shanghai for Science and Technology (USST) emerged from the University of Shanghai founded in 1906 and the German Medical and Engineering School set up in 1907. Carrying on its motto of “Integrity, Righteousness, Diligence, Love, Pondering, Learning, Aspiration, Ambition”, USST aims to cultivate students with knowledge, ambitions, as well as socialist core values. Adhering to the strategy of “developing in partnership with outstanding faculty”, the university now has 16…




see

Seeking for Multiple Faculty Positions in Capital Normal University (CNU)

About CNU
Capital Normal University (CNU) was founded in 1954. Being a national “Double-First Class” university and “Province-Ministry Co-sponsored” (Beijing and the Education Ministry) university, CNU has extensively broad disciplines including literature, sciences, engineering, management, law, education, foreign languages and arts. For over 60 years, CNU has cultivated more than 200 thousand graduates specializing in various fields. Currently, CNU is an important talent training base of Be…




see

Seeking for Faculty Positions at University of Shanghai for Science and Technology

About us
University of Shanghai for Science and Technology (USST) emerged from the University of Shanghai founded in 1906 and the German Medical and Engineering School set up in 1907. Carrying on its motto of “Integrity, Righteousness, Diligence, Love, Pondering, Learning, Aspiration, Ambition”, USST aims to cultivate students with knowledge, ambitions, as well as socialist core values. Adhering to the strategy of “developing in partnership with outstanding faculty”, the university now has 16…




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Project on Managing the Atom Seeking Full-Time Research Associate

The Managing the Atom (MTA) project at the Harvard Kennedy School is seeking a full-time Research Associate to support research projects directed by Professor Matthew Bunn on a range of nuclear policy topics including strategic stability and the future of nuclear arms control, reducing the risks of nuclear theft and terrorism worldwide, stemming the spread of nuclear weapons, and addressing key constraints on and risks of nuclear energy. Reporting to the MTA co-principal investigator Prof. Matthew Bunn, the Research Associate will play a major role in researching and writing papers and reports in these areas. 




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Foreseeable Unforeseeables

Contrary to what US President Donald Trump would like to believe, a pandemic like COVID-19 was predicted as recently as last year. After being caught off guard by yet another catastrophe, one wonders when political leaders, markets, and average citizens will start to take risk seriously.




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Foreseeable Unforeseeables

Contrary to what US President Donald Trump would like to believe, a pandemic like COVID-19 was predicted as recently as last year. After being caught off guard by yet another catastrophe, one wonders when political leaders, markets, and average citizens will start to take risk seriously.




see

Foreseeable Unforeseeables

Contrary to what US President Donald Trump would like to believe, a pandemic like COVID-19 was predicted as recently as last year. After being caught off guard by yet another catastrophe, one wonders when political leaders, markets, and average citizens will start to take risk seriously.




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Foreseeable Unforeseeables

Contrary to what US President Donald Trump would like to believe, a pandemic like COVID-19 was predicted as recently as last year. After being caught off guard by yet another catastrophe, one wonders when political leaders, markets, and average citizens will start to take risk seriously.








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Whitmarsh seeks wing clarification

McLaren team-boss left television viewers in no doubt what he thought about the legality of Red Bull's flexible front wing after Sebastian Vettel and Mark Webber dominated qualifying for the Hungarian Grand Prix




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Schumacher seeks rules clarification

Michael Schumacher has called for clarification of the safety car rules after the seven-time world champion completed his worst ever race finish in 259 grand prix starts




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Foreseeable Unforeseeables

Contrary to what US President Donald Trump would like to believe, a pandemic like COVID-19 was predicted as recently as last year. After being caught off guard by yet another catastrophe, one wonders when political leaders, markets, and average citizens will start to take risk seriously.




see

Foreseeable Unforeseeables

Contrary to what US President Donald Trump would like to believe, a pandemic like COVID-19 was predicted as recently as last year. After being caught off guard by yet another catastrophe, one wonders when political leaders, markets, and average citizens will start to take risk seriously.




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Generational war over the budget? Hard to see it in the numbers


Government spending on the elderly continues to climb.  Fueled by rapid growth in the number of Americans over age 65 and increased spending on benefits per person, public expenditures devoted to the elderly continue to edge up. A crucial question for future policy making is whether rising outlays on programs for the aged will squeeze out spending on programs for children, especially investments in their schooling. Many pessimists think this outcome is inevitable, and they urge us to reduce government commitments to the elderly to make room for spending on the young.

Federal spending is especially concentrated on the elderly. The Urban Institute publishes annual estimates of federal outlays on children and adults over 65. The estimates inevitably show a huge imbalance in spending on the two groups. In 2011, federal spending for the elderly amounted to almost $28,000 per person over 65.  In the same year, per capita spending on Americans under 19 amounted to just $4,900 per person. This means aged Americans received $5.72 in federal spending for every $1.00 received by a child 18 or younger.

The Urban Institute’s latest estimates show that federal spending on youngsters has trended down in recent years.  After reaching a peak of about $500 billion in 2010, expenditures on children fell 7 percent by 2012, and they have remained unchanged since then.

Future prospects are not encouraging. Urban Institute analysts predict that from 2014 to 2025, only 2 percent of federal spending growth will go to children. Almost 60 percent will be swallowed up by additional outlays on Social Security, Medicare, and Medicaid. Spending on many federal programs that provide benefits to children are financed out of discretionary programs. In contrast, big public programs for the aged seem to run on automatic pilot, with spending linked to changes in the cost of living and the size of the population past 65. Spending on most domestic discretionary programs is expected to be severely constrained as a result of Congressionally imposed budget caps. This is bad news for many federal programs targeted on children.

Focusing solely on federal government spending gives a misleading picture, however. While federal spending is heavily concentrated on the elderly, state and local spending tilts toward programs that help children, notably, through public school budgets.  Whereas aged Americans receive $5.72 in federal spending for each $1.00 received by someone under 19, those under 19 receive $10.11 in state and local spending for each $1.00 received by someone who is 65 or older. To be sure, total federal spending is considerably greater than that of state and local governments, but the imbalance of public spending on the young and the old is less extreme than federal budget statistics suggest.

Government spending on the aged is high because legislators (and voters) decided to establish government-backed pensions—through Social Security—in the 1930s and government-guaranteed health insurance for the elderly—through Medicare—in the 1960s.  In view of the overwhelming and enduring popularity of these two programs, most voters appear to think this was a sensible choice.  One implication of the policies is that Americans past 65 derive a sizable percentage of their retirement income, and an even bigger share of their health care, from public budgets.

The nation has not made an equivalent commitment to support the incomes or guarantee the health insurance of Americans under 65, except in special circumstances.  Those circumstances include temporary unemployment, a permanent work disability, and low household income.  Families headed by someone under 65 are expected to derive their support mainly from their jobs and from their own savings.  If non-aged families prosper, government spending on them falls.  If instead breadwinners become disabled or lose their jobs, government spending will increase as a result of higher disability payments, unemployment and food stamp benefits, and public assistance rolls.

Nearly all children are raised in families headed by someone under 65.  The government benefits they receive, except for free public schooling, increase in bad times and should decline when the unemployment rate falls.  The Urban Institute’s numbers are instructive.  Between 2007 and 2011, real federal spending on children increased 27 percent, or more than 6 percent a year, as the unemployment rate soared in the Great Recession. Federal spending on children then fell as unemployment—and outlays on government transfer payments—shrank.  For many categories of public spending on children, we cannot assume that lower spending signals a weaker commitment to children’s well-being. Instead it may signal a healthier private economy, a lower unemployment rate, and faster improvement in breadwinner incomes.

Of course, some components of government spending on children do not automatically rise in a slumping economy or shrink when breadwinners’ earnings improve.  Public investments in children’s preschool and K-12 education should be adjusted to reflect the needs of children for compensatory instruction and the expected payoff of added investment in schooling.  Statistics on public school budgets show that spending per pupil has increased considerably faster than inflation and faster than GDP per person over the past seven decades (see Chart 1). Whether spending has increased as fast as warranted is debatable, but rising government spending on the aged has not caused per-pupil spending on K-12 schools to shrink.

Government spending on children’s health has also increased over time as public insurance for children has been expanded.  In 2014 just 6 percent of Americans under age 19 lacked health insurance for the entire year.  The only age group with higher health insurance coverage was the population past 65, which is covered by Medicare (see Chart 2).  The main explanation for rising insurance coverage among children is that federal and state health insurance programs have been expanded to cover most low-income children.  Insurance coverage of children can and should be improved, but a sizeable expansion of public insurance has occurred despite the increase in public spending on the elderly.

The presumption that rising outlays on programs for Americans past 65 must come at the expense of spending on children rests on the unstated assumption that voters will zealously defend programs for the aged while tolerating cuts in programs that fund education, income protection, and health coverage for the young.  The trend toward higher public spending on the elderly has been underway for at least five decades, but the predicted cuts in spending on the young have yet to materialize.

Editor's Note: this op-ed first appeared in Real Clear Markets.

Authors

Publication: Real Clear Markets
     
 
 




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A Restoring Prosperity Case Study: Chattanooga Tennessee

Chattanooga a few years ago faced what many smaller cities are struggling with today—a sudden decline after years of prosperity in the "old" economy. This case study offers a roadmap for these cities by chronicling Chattanooga's demise and rebirth.

Chattanooga is located in the southern end of the Tennessee Valley where the Tennessee River cuts through the Smoky Mountains and the Cumberland Plateau. The city’s location, particularly its proximity to the Tennessee River, has been one of its greatest assets. Today, several major interstates (I-24, I-59, and I-75) run through Chattanooga, making it a hub of transportation business. The city borders North Georgia and is less than an hour away from both Alabama and North Carolina. Atlanta, Nashville, and Birmingham are all within two hours travel time by car.

Chattanooga is Tennessee’s fourth largest city, with a population in 2000 of 155,554, and it covers an area of 143.2 square miles. Among the 200 most populous cities in the United States, Chattanooga—with 1,086.5 persons per square mile—ranks 190th in population density.2 It is the most populous of 10 municipalities in Hamilton County, which has a population of 307,896, covers an area of 575.7 square miles, and has a population density of 534.8 persons per square mile.

With its extensive railroads and river access, Chattanooga was at one time the “Dynamo of Dixie”—a bustling, midsized, industrial city in the heart of the South. By 1940, Chattanooga’s population was centered around a vibrant downtown and it was one of the largest cities in the United States. Just 50 years later, however, it was in deep decline. Manufacturing jobs continued to leave. The city’s white population had fled to the suburbs and downtown was a place to be avoided, rather than the economic center of the region. The city lost almost 10 percent of its population during the 1960s, and another 10 percent between 1980 and 1990. It would have lost more residents had it not been for annexation of outlying suburban areas.

The tide began to turn in the 1990s, with strategic investments by developing public-private partnerships—dubbed the “Chattanooga way.” These investments spurred a dramatic turnaround. The city’s population has since stabilized and begun to grow, downtown has been transformed, and it is once again poised to prosper in the new economy as it had in the old.

This report describes how Chattanooga has turned its economy around. It begins with a summary of how the city grew and developed during its first 150 years before describing the factors driving its decline. The report concludes by examining the partnerships and planning that helped spur Chattanooga’s current revitalization and providing valuable lessons to other older industrial cities trying to ignite their own economic recovery. 

Download Case Study » (PDF)

Downloads

Authors

  • David Eichenthal
  • Tracy Windeknecht
      
 
 




see

The 5 kinds of cities we’ll see in the populist era

Last summer, as Donald Trump was pledging to Make America Great Again through tariffs and a “great wall” along the United States’ southern border, the Leave campaign in the United Kingdom urged Brits to “take back control” of their country by exiting the European Union. Although many urban voters in both countries rejected these ideas,…

       




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Polling shows Americans see COVID-19 as a crisis, don’t think US is overreacting

As soon as the novel coronavirus began spreading across the country, some pundits—and on occasion President Trump—alleged that health experts and the media were exaggerating the problem and that policy makers were responding with measures that the American people would not tolerate. The high-quality survey research published in recent days makes it clear that the…

       




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Seeking solutions for Somalia

Despite important progress through years of international counterterrorism, counterinsurgency, and state-building assistance, peace and sustainable stabilization remain elusive in Somalia. Al-Shabab remains entrenched throughout vast parts of Somalia and regularly conducts deadly terrorist attacks even in Mogadishu. Capacities of Somali national security remain weak, and while the Trump administration has significantly augmented U.S. anti-Shabab air…

       




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Brookings survey finds 58% see manufacturing as vital to US economy, but only 17% are very confident in its future

Manufacturing is a crucial part of the U.S. economy. According to the U.S. census, around 11.1 million workers are employed in the sector, and it generates about $5.4 trillion in economic activity annually. Yet this area currently faces significant headwinds. The June IHS Markit Manufacturing Purchasing Managers Index fell to its worst reading since 2009…

       




see

A Restoring Prosperity Case Study: Chattanooga Tennessee

Chattanooga a few years ago faced what many smaller cities are struggling with today—a sudden decline after years of prosperity in the "old" economy. This case study offers a roadmap for these cities by chronicling Chattanooga's demise and rebirth.

Chattanooga is located in the southern end of the Tennessee Valley where the Tennessee River cuts through the Smoky Mountains and the Cumberland Plateau. The city’s location, particularly its proximity to the Tennessee River, has been one of its greatest assets. Today, several major interstates (I-24, I-59, and I-75) run through Chattanooga, making it a hub of transportation business. The city borders North Georgia and is less than an hour away from both Alabama and North Carolina. Atlanta, Nashville, and Birmingham are all within two hours travel time by car.

Chattanooga is Tennessee’s fourth largest city, with a population in 2000 of 155,554, and it covers an area of 143.2 square miles. Among the 200 most populous cities in the United States, Chattanooga—with 1,086.5 persons per square mile—ranks 190th in population density.2 It is the most populous of 10 municipalities in Hamilton County, which has a population of 307,896, covers an area of 575.7 square miles, and has a population density of 534.8 persons per square mile.

With its extensive railroads and river access, Chattanooga was at one time the “Dynamo of Dixie”—a bustling, midsized, industrial city in the heart of the South. By 1940, Chattanooga’s population was centered around a vibrant downtown and it was one of the largest cities in the United States. Just 50 years later, however, it was in deep decline. Manufacturing jobs continued to leave. The city’s white population had fled to the suburbs and downtown was a place to be avoided, rather than the economic center of the region. The city lost almost 10 percent of its population during the 1960s, and another 10 percent between 1980 and 1990. It would have lost more residents had it not been for annexation of outlying suburban areas.

The tide began to turn in the 1990s, with strategic investments by developing public-private partnerships—dubbed the “Chattanooga way.” These investments spurred a dramatic turnaround. The city’s population has since stabilized and begun to grow, downtown has been transformed, and it is once again poised to prosper in the new economy as it had in the old.

This report describes how Chattanooga has turned its economy around. It begins with a summary of how the city grew and developed during its first 150 years before describing the factors driving its decline. The report concludes by examining the partnerships and planning that helped spur Chattanooga’s current revitalization and providing valuable lessons to other older industrial cities trying to ignite their own economic recovery. 

Download Case Study » (PDF)

Downloads

Authors

  • David Eichenthal
  • Tracy Windeknecht
      
 
 




see

In 6 charts, see what Americans really think about US policy toward Syria, Iran, and Afghanistan

The following is based on new findings from two consecutive  University of Maryland Critical Issues Polls, conducted September 3-20, and October 4-10. The full results can be found here, and the methodology and questionnaire here. 1From the day President Trump announced his decision to withdraw troops from northern Syria, which we started measuring on October…

       




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Refugees: Why Seeking Asylum is Legal and Australia’s Policies are Not

      
 
 




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Trillion dollar deficits as far as the eye can see: Four take-aways from CBO’s new budget outlook

The Congressional Budget Office's new Budget and Economic Outlook provides a useful update on the state of the economy and the budget. While the headline news is the return of trillion-dollar annual deficits, there is much more to consider. Here are four take-aways from the latest projections: 1. Interest rates have fallen and will remain…

       




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Whole Foods' John Mackey a Climate Change Skeptic?!? Seems So.

Back when Whole Foods CEO John Mackey weighed in on-slash-stuck his personal foot in his professional mouth about healthcare, I stayed out of the debate. I assumed, wrongly in hindsight, that most people already knew that




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SRD Change09: Students Seek to Inspire, Provoke and Change Design

SRD Change is the annual exhibition of new graduate design and ideas that address our those issues which will impact our future. Like issues of sustainability, environmental change and responsibility, social equity and community. The Society for




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Not much to see in Vancouver's first Passive House apartment block

And that's just the way the architect and developer like it.




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New Wave Energy Device Could See 200 Commercial Units in the Next Five Years

The Searaser takes a novel approach to wave energy generation. New owners Ecotricity - pioneers of wind power in Britain - are aiming for mass deployment in the next five years.




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Tennessee Town Passes Nation's First Green Food Resolution

Beating out New York City, the small Tennessee town of Signal Mountain is the first in the nation to pass a Green Food Resolution. But, just what does a Green Food Resolution mean for farmers, consumers, and




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Tennessee Valley Authority Expecting Nuctuplets

TVA and reactor-maker Babcock and Wilcox have agreed to work together to see if they can build up to 6 "small reactors." Nuctuplets, then? They can knock these




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Sustainable Development, Smart Growth and Agenda 21 Now Illegal in Tennessee

Because everyone knows that bike paths are just the thin edge of the wedge. Next, they come for your cars.




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Corporations Wrote a Law Requiring Climate Denial be Taught in School. Tennessee Just Passed It.

Would you let corporations decide how climate science gets taught in your kids' classroom? That's what's happening in Tennessee.




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Tennessee Passes Law Allowing Creationism, Climate Denial to be Taught in Classroom

Woops.




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Happy Eightieth Birthday, Tennessee Valley Authority

It may be old, dirty and coal powered now, but it was once a vision of a brighter future, was a giant stimulus project and helped win WWII.




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Chic Tennessee treehouse hideaway built for $1,500

Simple but striking, this small treehouse retreat was built by hand and furnished with repurposed flea market finds.




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Twitter-enabled vending machine gives out free seeds for tweets

To promote their fantastic garden grant program, Seeds of Change is bringing a seed vending machine and photo booth to several US cities, where visitors can tweet for seeds.




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Rob Greenfield: How we can be the change we want to see in a "messed up" world

When it comes to walking the green and sustainable walk, Greenfield really puts it all on the line.




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Breaking the seed bank to feed the future

Can science use the genes engineered by nature instead of genetic engineering in the face of a pending food crisis?




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Detroit Auto Show 2009: All-New Toyota Prius to be Unveiled Soon (But We've Already Seen It)

The Best-Selling Hybrid Car Gets a MakeoverIt might not be very suspenseful because we've all already seen leaked shots of the 3rd generation Toyota Prius hybrid (see below -




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Hungary Destroys All GM Maize Fields - Farmers Claim Ignorance Over Banned Seeds

Hungary already has a ban on genetically modified crops, so this is a bit more complicated than it may seem at first. As PlanetSave reports Hungary has destroyed approximately 1000 acres of maize fields found to




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EPA surprise: Agency seeks to cancel approval of toxic pesticide

And the company that makes the chemical, Bayer CropScience, refuses to agree.




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Seeds and Coconuts Bring Dozens of New, Unexpected Products to Expo West 2012

From chia to hemp, seeds were a prominent force among the 500-plus new products at the annual tradeshow in Los Angeles.




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Why add hemp seed to your diet? Here are the benefits

Hemp is healthy!




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These are the coolest sustainable shoes we've ever seen

SAOLA is a new French brand making slick sneakers from recycled material and algae foam.