Resurrecting an old idea about assessing school quality could allow schools to examine a broad range of data on performance and practices and lead to improvement.

Shea Weber gets inducted into the Hockey Hall of Fame after an impressive career.

The 30-year-old had only played 13 games this season.

Longtime Red Wings GM and Hockey Hall of Famer Ken Holland joined the NHL in a new consulting role just months after parting with the Edmonton Oilers.

Former Red Wings general manager Ken Holland is taking on a new role with the NHL's league office

The Winnipeg Jets will be without defenceman Logan Stanley for the short-term future.

Poile, Nashville's first-ever general manager who retired in 2023, was inducted into the Hockey Hall of Fame alongside former Predators captain Shea Weber.

The Calgary Flames' fifth game in eight nights and three time zones was a tough one they need to learn from

In Tuesday night's Republican primary in West Virginia, Robert Karnes, a West Virginia Republican state senator who lashed out at teachers during their nine-day strike, lost to pro-labor candidate Bill Hamilton.

Lawmakers effectively killed the controversial education bill that had prompted the second statewide strike in two years.

A school leader outlines how research findings on reducing achievement gaps are reflected in practice at her New Mexico school.

A federal investigation of Chicago's failures to respond to sexual violence in schools raises troubling questions for school districts nationwide.

Lawmakers in Illinois are considering a bill that would require children to start kindergarten if they are 5 on or before May 31, with exceptions for summer birthdays.

On Wednesday at Moody Center, a Lamar team that went 24-7 last season should provide a tougher test for the Longhorns than in their season opener.

Donna M. Wilcock
May 1, 2003; 23:3745-3751
Development Plasticity Repair

Guo-qiang Bi
Dec 15, 1998; 18:10464-10472
Articles

Michele Deodato
Oct 2, 2024; 44:e2308232024-e2308232024
BehavioralSystemsCognitive

Kyle E. Mathewson
Mar 4, 2009; 29:2725-2732
BehavioralSystemsCognitive

Vertebrate nervous systems use the axon initial segment (AIS) to initiate action potentials and maintain neuronal polarity. The microtubule-associated protein tripartite motif containing 46 (TRIM46) was reported to regulate axon specification, AIS assembly, and neuronal polarity through the bundling, or fasciculation, of microtubules in the proximal axon. However, these claims are based on TRIM46 knockdown in cultured neurons. To investigate TRIM46 function in vivo, we examined male and female TRIM46 knock-out mice. Contrary to previous reports, we find that TRIM46 is dispensable for axon specification and AIS formation. TRIM46 knock-out mice are viable, have normal behavior, and have normal brain structure. Thus, TRIM46 is not required for AIS formation, axon specification, or nervous system function. However, we confirm that TRIM46 is required for microtubule fasciculation. We also show TRIM46 enrichment in the first ~100 μm of axon occurs independently of ankyrinG (AnkG) in vivo, although AnkG is required to restrict TRIM46 only to the AIS. Our results highlight the need for further investigation of the mechanisms by which the AIS and microtubules interact to shape neuronal structure and function.

Sleep is known to drive the consolidation of motor memories. During nonrapid eye movement (NREM) sleep, the close temporal proximity between slow oscillations (SOs) and spindles ("nesting" of SO-spindles) is known to be essential for consolidation, likely because it is closely associated with the reactivation of awake task activity. Interestingly, recent work has found that spindles can occur in temporal clusters or "trains." However, it remains unclear how spindle trains are related to the nesting phenomenon. Here, we hypothesized that spindle trains are more likely when SOs co-occur in the prefrontal and motor cortex. We conducted simultaneous neural recordings in the medial prefrontal cortex (mPFC) and primary motor cortex (M1) of male rats training on the reach-to-grasp motor task. We found that intracortically recorded M1 spindles are organized into distinct temporal clusters. Notably, the occurrence of temporally precise SOs between mPFC and M1 was a strong predictor of spindle trains. Moreover, reactivation of awake task patterns is much more persistent during spindle trains in comparison with that during isolated spindles. Together, our work suggests that the precise coupling of SOs across mPFC and M1 may be a potential driver of spindle trains and persistent reactivation of motor memory during NREM sleep.

Aggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We found that in Drosophila melanogaster, a set of neurons, which we call CL062, previously shown to mediate male aggression also mediate female aggression. These neurons elicit aggression acutely and without the presence of a target. Although the same set of actions is elicited in males and females, the overall behavior is sexually dimorphic. The CL062 neurons do not express fruitless, a gene required for sexual dimorphism in flies, and expressed by most other neurons important for controlling fly aggression. Connectomic analysis in a female electron microscopy dataset suggests that these neurons have limited connections with fruitless expressing neurons that have been shown to be important for aggression and signal to different descending neurons. Thus, CL062 is part of a monomorphic circuit for aggression that functions parallel to the known dimorphic circuits.

Representatives of all countries in Latin America and the Caribbean have gathered here this week to agree on the actions needed to definitively eradicate hunger in the region before 2025. [...]

Human beings and chimps share as much as 98 percent of their DNA. If our species are so similar, can chimps be genetically engineered to be more like us?

Scientists have created thin polymer sheets that expand and contract when in contact with water

Credit: David Marshall, University of Bristol

Kenneth Morris is the great-great-great-grandson of the heralded abolitionist and helped compile an illustrated biography of his ancestor. (Credit: Drew Gardner)

Megan Leftwich, an engineering professor at George Washington University, is building a robotic flipper based on her observations of sea lions

In the Virunga National Forest, the mountain gorilla population sits in the middle of a war zone in the Democratic Republic of the Congo as forest rangers track and keep a watchful eye on the threatened primates Music: Kevin MacLeod

Christopher Nolan's epic new film "Oppenheimer" is no mere biopic… nor is it the first attempt to capture the father of the atomic bomb in fiction. We look at prior dramatizations of this very complicated man—including one wherein J. Robert Oppenheimer played himself!—and examine why they worked or didn't. In this episode: Physicist-turned-photographer Minesh Bacrania shares his experience photographing inside the top-secret labs at Los Alamos National Laboratory, where J. Robert Oppenheimer and other scientists created the first nuclear weapon. Next, with Christopher Nolan’s film Oppenheimer exceeding commercial expectations, Smithsonian magazine writer Andy Kifer discusses the complexities of Oppenheimer's genius and how prior attempts to depict him in film and television and on stage have fared. Read Andy Kifer’s “The Real Story Behind Christopher Nolan’s Oppenheimer” here (https://www.smithsonianmag.com/history/the-real-history-behind-christopher-nolans-oppenheimer-180982529/) . See Minesh Bacrania’s photographs of Los Alamos and read Smithsonian senior editor Jennie Rothenberg Gritz’s text here (https://www.smithsonianmag.com/history/exclusive-behind-scenes-look-los-alamos-lab-where-robert-oppenheimer-created-atomic-bomb-180982336/) or in the July/August 2023 issue of Smithsonian. Original release date: July 27, 2023 There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Genevieve Sponsler, Adriana Rozas Rivera, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Episode artwork by Emily Lankiewicz. Music by APM Music.

Read more about Haleakala: http://j.mp/ufv44s The Hawaiian volcano, with its unique vegetation and meditative winds, has a spiritual connection to the native population

Kip Thorne, Rainer Weiss, Barry Barish and Ronald Drever | Smithsonian Magazine’s 2016 American Ingenuity Award Winners for Physical Sciences In February, physicists announced the first-ever detection of gravitational waves—a phenomenon Albert Einstein predicted back in 1915. The faint reverberation, from two merging black holes 1.3 billion light-years ago, registered in the two giant detectors that make up the Laser Interferometer Gravitational-Wave Observatory, or LIGO. It took decades for LIGO’s founders—Weiss, of MIT, and Thorne and Drever, of Cal Tech—to amass the necessary funding and brainpower. Barish, a particle physicist at CalTech, became LIGO’s director and expanded its work to include more than 1,000 researchers worldwide. Their revolutionary achievement opens the way for a new understanding of the universe, perhaps even a glimpse of the Big Bang. Read more about their work: http://smithmag.co/FZBFeP | #IngenuityAwards And more about the American Ingenuity Awards: http://smithmag.co/77xPqy

The North American Orchid Conservation Center is working to ensure the survival of some of the most unique plants in the world

Equipped with wings and a propeller, Moulton Taylor Aerocar aerobile was capable of taking off from a stoplight or the runway

See how geometric designs are inspiring new ways to make stretchy materials. (Video by Ahmad Rafsanjani and Damiano Pasini/McGill University)

Looking at the future of geopolitics, the author reveals the surprising results of his research. Read more at http://www.smithsonianmag.com/specialsections/40th-anniversary/George-Friedman-on-World-War-III.html

An exclusive group of thought leaders gathered at the museum to discuss how the world prepares for the next global pandemic, raises public awareness, and explores potential responses and solutions

The 6888th Central Postal Directory Battalion was the only unit comprised entirely of Black women to have been deployed overseas during World War II, and it had served a critical function: clearing the backlog of mail that marked the only line of communication between American soldiers in Europe and their loved ones back home. In this episode, we speak with retired Army Colonel Edna Cummings, who made it her business to get the 6888 their belated recognition, and with Smithsonian magazine senior writer Jennie Rothenberg Gritz, who wrote about Col. Cummings' quest (https://www.smithsonianmag.com/history/how-all-black-female-WWII-unit-saved-morale-battlefield-180981540/) for the March 2023 issue of Smithsonian. NOTE: In the interval since we recorded our interview with Col. Cummings, another veteran from the 6888 has died. With the passing of Crescencia J. Garcia last month at the age of 103, there are now five women who served in the 6888 during World War II who remain alive. Learn more about the women of the 6888th Central Postal Battalion at the Women of the 6888th site (https://www.womenofthe6888th.org/) . Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Episode artwork by Emily Lankiewicz. Music by APM Music.

The 12,000 year old skeleton of a teenage girl was found in Hoyo Negro, an underwater cave system on the Yucatan Peninsula.

The two discussed their ancestors’ legacy more than 150 years after the famous figures both attended the Seneca Falls Convention. (Credit: Drew Gardner)

A learning simulation, combined with fMRI readings, is able to predict the visualizations seen by a dreamer in real time

Our host, Eric Schulze, explains how science is tackling this puzzling question from space.

Smithsonian magazine commissioned Drew Gardner for a project that connects Black Americans today to their lost ancestry. Read about Gardner’s project and process, as well as more details about the subjects of this incredible series here: https://www.smithsonianmag.com/history/descendants-black-civil-war-heroes-wear-heritage-pride-180983397/ Video produced by Sierra Theobald. Special thanks to Drew Gardner Additional credits: Emma MacBeath, WikiTree US Black Heritage project; Ottawa Goodman, research and coordinator; Sam Dole, Penumbra Foundation; Elizabeth Zuck, set design; Calvin Osbourne, props and costume; Angela Huff, hair and make up; Diego Huerta, Lexia Krebs, behind-the-scenes filming; background prints by Fujifilm USA

David Lynch | Smithsonian Magazine’s 2016 American Ingenuity Award Winner for Education As a filmmaker, Lynch has a reputation for creating dark, surreal movies such as Eraserhead, Blue Velvet and Wild at Heart as well as the TV show “Twin Peaks.” In the education world, he's becoming known for something very different: promoting inner peace. Over the past decade, the David Lynch Foundation has sponsored Transcendental Meditation classes for half a million children in places as far-flung as the Bronx, Detroit, Los Angeles, Congo and the West Bank. The program, called Quiet Time, is now at the center of one of the largest-ever studies of meditation for children—a 6,800-pupil research project conducted by the Crime Lab at the University of Chicago and designed to learn if meditation can help kids in highly stressful environments fare better at home and in school. Read more about Lynch’s work: http://smithmag.co/9sHhtm | #IngenuityAwards And more about the American Ingenuity Awards: http://smithmag.co/77xPqy

Capturing a piece of an asteroid and bringing it to Earth is even more difficult than it is time-consuming. After four years in space, NASA’s OSIRIS-REx craft made a brief landing on the asteroid Bennu to collect samples of the ancient rock. Six months later, part of the spacecraft began its journey home to Earth, and earlier this fall, that sample collection canister landed, via parachute, in Utah. Scientists will be studying those samples of Bennu for decades in the hope of unlocking the mystery of how life on Earth began — but they’ve already learned enough to get them excited. In this episode, we speak with Linda Shiner, the former editor of Air & Space / Smithsonian magazine, about the challenges and triumphs of the OSIRIS-REx mission, and what scientists hope it will teach us about how life on Earth began. Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Fact-checking by Stephanie Abramson. Episode artwork by Emily Lankiewicz. Music by APM Music.

Investigators discovered that the original print of "The Roaring Lion" had been sold to a buyer in Italy

Scientists identified traces of the drug in the brain tissue of two individuals buried in the crypt of a hospital in Milan

New research suggests the sarcophagus' occupant, previously known only as "the horseman," is Joachim du Bellay, a French Renaissance poet who died in 1560

The baby pygmy hippopotamus in a Thailand zoo has taken the internet by storm, and keepers hope she will help gain momentum for conservation efforts