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An encyclopedia of the practice of medicine, based on bacteriology / by J. Buchanan.

New York : R.R. Russell, 1891.




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Essai clinique et expérimental sur la fièvre des tuberculeux (toxicité des crachats, toxicité des urines) / par Le Docteur Edouard Chretien.

Paris : Steinheil, 1896.




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Essai sur la digitale pourprée / par James Sanders ; traduit de l'anglais par A.F.G. Murat, avec des notes et des réflexions sur la matière médicale par le traducteur.

Paris : Ancelle, 1812.




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Essai sur la syringomyelie / par le Docteur Critzman.

Paris : G. Steinheil, 1892.




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An Unexpected 'Education Governor' and What's Next for Florida

Ron DeSantis had a thin record on K-12 issues as a Florida congressman, but as a first-term Republican governor he’s pushed an aggressive agenda on issues such as vouchers, teacher salaries and bonus pay, and even the common core.




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Walz expected to keep Minnesota schools closed




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Schools Lean on Staff Who Speak Students' Language to Keep English-Learners Connected

The rocky shift to remote learning has exacerbated inequities for the nation's 5 million English-learners. An army of multilingual liaisons work round the clock to plug widening gaps.




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An episode in 'Every man in his humour' by Ben Jonson: Charles Dickens in character as Captain Bobadill is awakened after a hard night's drinking. Lithograph by T.H. Maguire after C.R. Leslie.

[London?]




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William Macready in character as Werner in the play Werner by Lord Byron. Engraving by C.W. Sharpe after D. Maclise.

[London?]




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Report upon the Scott Moncrieff system for the bacteriological purification of sewage / by Alexander C. Houston.

[London] : Waterlow Bros. & Layton, Limited, [1893]




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After Protracted Political Spat, Missouri Rehires Fired State Schools Chief

Former Republican Missouri Gov. Eric Greitens appointed enough board members to have Commissioner Margie Vandeven fired last year, but now that he's gone, the state board decided to hire her back.




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Drug abuse treatment client characteristics and pretreatment behaviors : 1979-1981 TOPS admission cohorts / Robert L. Hubbard, Robert M. Bray, Elizabeth R. Cavanaugh, J. Valley Rachal, S. Gail Craddock, James J. Collins, Margaret Allison ; Research Triang

Rockville, Maryland : National Institute on Drug Abuse, 1986.




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Addicted women : family dynamics, self perceptions, and support systems.

Rockville, Maryland : National Institute on Drug Abuse, 1979.




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Psychosocial characteristics of drug-abusing women / by Marvin R. Burt, principal investigator ; Thomas J. Glynn, Barbara J. Sowder ; Burt Associates, Inc.

Rockville, Maryland : National Institute on Drug Abuse, 1979.




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Family therapy : a summary of selected literature.

Rockville, Maryland : National Institute on Drug Abuse, 1980.




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Survey of drug information needs and problems associated with communications directed to practicing physicians : part III : remedial ad survey / [Arthur Ruskin, M.D.]

Springfield, Virginia : National Technical Information Service, 1974.




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Selected Poems of Henry Lawson: Correspondence: Vol.1




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Sabrina Ionescu, Ruthy Hebard, Satou Sabally on staying connected, WNBA Draft, Oregon's historic season

Pac-12 Networks' Ashley Adamson catches up with Oregon's "Big 3" of Sabrina Ionescu, Ruthy Hebard and Satou Sabally to hear how they're adjusting to the new world without sports while still preparing for the WNBA Draft on April 17. They also share how they're staying hungry for basketball during the hiatus.




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A Bayesian approach to disease clustering using restricted Chinese restaurant processes

Claudia Wehrhahn, Samuel Leonard, Abel Rodriguez, Tatiana Xifara.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1449--1478.

Abstract:
Identifying disease clusters (areas with an unusually high incidence of a particular disease) is a common problem in epidemiology and public health. We describe a Bayesian nonparametric mixture model for disease clustering that constrains clusters to be made of adjacent areal units. This is achieved by modifying the exchangeable partition probability function associated with the Ewen’s sampling distribution. We call the resulting prior the Restricted Chinese Restaurant Process, as the associated full conditional distributions resemble those associated with the standard Chinese Restaurant Process. The model is illustrated using synthetic data sets and in an application to oral cancer mortality in Germany.




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Expected Policy Gradients for Reinforcement Learning

We propose expected policy gradients (EPG), which unify stochastic policy gradients (SPG) and deterministic policy gradients (DPG) for reinforcement learning. Inspired by expected sarsa, EPG integrates (or sums) across actions when estimating the gradient, instead of relying only on the action in the sampled trajectory. For continuous action spaces, we first derive a practical result for Gaussian policies and quadratic critics and then extend it to a universal analytical method, covering a broad class of actors and critics, including Gaussian, exponential families, and policies with bounded support. For Gaussian policies, we introduce an exploration method that uses covariance proportional to the matrix exponential of the scaled Hessian of the critic with respect to the actions. For discrete action spaces, we derive a variant of EPG based on softmax policies. We also establish a new general policy gradient theorem, of which the stochastic and deterministic policy gradient theorems are special cases. Furthermore, we prove that EPG reduces the variance of the gradient estimates without requiring deterministic policies and with little computational overhead. Finally, we provide an extensive experimental evaluation of EPG and show that it outperforms existing approaches on multiple challenging control domains.




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Stein characterizations for linear combinations of gamma random variables

Benjamin Arras, Ehsan Azmoodeh, Guillaume Poly, Yvik Swan.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 2, 394--413.

Abstract:
In this paper we propose a new, simple and explicit mechanism allowing to derive Stein operators for random variables whose characteristic function satisfies a simple ODE. We apply this to study random variables which can be represented as linear combinations of (not necessarily independent) gamma distributed random variables. The connection with Malliavin calculus for random variables in the second Wiener chaos is detailed. An application to McKay Type I random variables is also outlined.




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On estimating the location parameter of the selected exponential population under the LINEX loss function

Mohd Arshad, Omer Abdalghani.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 1, 167--182.

Abstract:
Suppose that $pi_{1},pi_{2},ldots ,pi_{k}$ be $k(geq2)$ independent exponential populations having unknown location parameters $mu_{1},mu_{2},ldots,mu_{k}$ and known scale parameters $sigma_{1},ldots,sigma_{k}$. Let $mu_{[k]}=max {mu_{1},ldots,mu_{k}}$. For selecting the population associated with $mu_{[k]}$, a class of selection rules (proposed by Arshad and Misra [ Statistical Papers 57 (2016) 605–621]) is considered. We consider the problem of estimating the location parameter $mu_{S}$ of the selected population under the criterion of the LINEX loss function. We consider three natural estimators $delta_{N,1},delta_{N,2}$ and $delta_{N,3}$ of $mu_{S}$, based on the maximum likelihood estimators, uniformly minimum variance unbiased estimator (UMVUE) and minimum risk equivariant estimator (MREE) of $mu_{i}$’s, respectively. The uniformly minimum risk unbiased estimator (UMRUE) and the generalized Bayes estimator of $mu_{S}$ are derived. Under the LINEX loss function, a general result for improving a location-equivariant estimator of $mu_{S}$ is derived. Using this result, estimator better than the natural estimator $delta_{N,1}$ is obtained. We also shown that the estimator $delta_{N,1}$ is dominated by the natural estimator $delta_{N,3}$. Finally, we perform a simulation study to evaluate and compare risk functions among various competing estimators of $mu_{S}$.




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A primer on the characterization of the exchangeable Marshall–Olkin copula via monotone sequences

Natalia Shenkman.

Source: Brazilian Journal of Probability and Statistics, Volume 34, Number 1, 127--135.

Abstract:
While derivations of the characterization of the $d$-variate exchangeable Marshall–Olkin copula via $d$-monotone sequences relying on basic knowledge in probability theory exist in the literature, they contain a myriad of unnecessary relatively complicated computations. We revisit this issue and provide proofs where all undesired artefacts are removed, thereby exposing the simplicity of the characterization. In particular, we give an insightful analytical derivation of the monotonicity conditions based on the monotonicity properties of the survival probabilities.




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Odysseus asleep : uncollected sequences, 1994-2019

Sanger, Peter, 1943- author.
9781554472048




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On the impact of selected modern deep-learning techniques to the performance and celerity of classification models in an experimental high-energy physics use case. (arXiv:2002.01427v3 [physics.data-an] UPDATED)

Beginning from a basic neural-network architecture, we test the potential benefits offered by a range of advanced techniques for machine learning, in particular deep learning, in the context of a typical classification problem encountered in the domain of high-energy physics, using a well-studied dataset: the 2014 Higgs ML Kaggle dataset. The advantages are evaluated in terms of both performance metrics and the time required to train and apply the resulting models. Techniques examined include domain-specific data-augmentation, learning rate and momentum scheduling, (advanced) ensembling in both model-space and weight-space, and alternative architectures and connection methods.

Following the investigation, we arrive at a model which achieves equal performance to the winning solution of the original Kaggle challenge, whilst being significantly quicker to train and apply, and being suitable for use with both GPU and CPU hardware setups. These reductions in timing and hardware requirements potentially allow the use of more powerful algorithms in HEP analyses, where models must be retrained frequently, sometimes at short notice, by small groups of researchers with limited hardware resources. Additionally, a new wrapper library for PyTorch called LUMINis presented, which incorporates all of the techniques studied.




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Training and Classification using a Restricted Boltzmann Machine on the D-Wave 2000Q. (arXiv:2005.03247v1 [cs.LG])

Restricted Boltzmann Machine (RBM) is an energy based, undirected graphical model. It is commonly used for unsupervised and supervised machine learning. Typically, RBM is trained using contrastive divergence (CD). However, training with CD is slow and does not estimate exact gradient of log-likelihood cost function. In this work, the model expectation of gradient learning for RBM has been calculated using a quantum annealer (D-Wave 2000Q), which is much faster than Markov chain Monte Carlo (MCMC) used in CD. Training and classification results are compared with CD. The classification accuracy results indicate similar performance of both methods. Image reconstruction as well as log-likelihood calculations are used to compare the performance of quantum and classical algorithms for RBM training. It is shown that the samples obtained from quantum annealer can be used to train a RBM on a 64-bit `bars and stripes' data set with classification performance similar to a RBM trained with CD. Though training based on CD showed improved learning performance, training using a quantum annealer eliminates computationally expensive MCMC steps of CD.




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Efficient Characterization of Dynamic Response Variation Using Multi-Fidelity Data Fusion through Composite Neural Network. (arXiv:2005.03213v1 [stat.ML])

Uncertainties in a structure is inevitable, which generally lead to variation in dynamic response predictions. For a complex structure, brute force Monte Carlo simulation for response variation analysis is infeasible since one single run may already be computationally costly. Data driven meta-modeling approaches have thus been explored to facilitate efficient emulation and statistical inference. The performance of a meta-model hinges upon both the quality and quantity of training dataset. In actual practice, however, high-fidelity data acquired from high-dimensional finite element simulation or experiment are generally scarce, which poses significant challenge to meta-model establishment. In this research, we take advantage of the multi-level response prediction opportunity in structural dynamic analysis, i.e., acquiring rapidly a large amount of low-fidelity data from reduced-order modeling, and acquiring accurately a small amount of high-fidelity data from full-scale finite element analysis. Specifically, we formulate a composite neural network fusion approach that can fully utilize the multi-level, heterogeneous datasets obtained. It implicitly identifies the correlation of the low- and high-fidelity datasets, which yields improved accuracy when compared with the state-of-the-art. Comprehensive investigations using frequency response variation characterization as case example are carried out to demonstrate the performance.




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Staying connected

Stay connected with our virtual drop-in sessions for NSW public library staff.




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Structured object-oriented formal language and method : 9th International Workshop, SOFL+MSVL 2019, Shenzhen, China, November 5, 2019, Revised selected papers

SOFL+MSVL (Workshop) (9th : 2019 : Shenzhen, China)
9783030414184 (electronic bk.)




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Space information networks : 4th International Conference, SINC 2019, Wuzhen, China, September 19-20, 2019, Revised Selected Papers

SINC (Conference) (4th : 2019 : Wuzhen, China)
9789811534423 (electronic bk.)




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Semantic technology : 9th Joint International Conference, JIST 2019, Hangzhou, China, November 25-27, 2019, Revised selected papers

Joint International Semantic Technology Conference (9th : 2019 : Hangzhou, China)
9789811534126 (electronic bk.)




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Enterprise information systems : 21st International Conference, ICEIS 2019, Heraklion, Crete, Greece, May 3-5, 2019, Revised Selected Papers

International Conference on Enterprise Information Systems (21st : 2019 : Ērakleion, Greece)
9783030407834 (electronic bk.)




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Current microbiological research in Africa : selected applications for sustainable environmental management

9783030352967 (electronic bk.)




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Computer security : ESORICS 2019 International Workshops, IOSec, MSTEC, and FINSEC, Luxembourg City, Luxembourg, September 26-27, 2019, Revised Selected Papers

European Symposium on Research in Computer Security (24th : 2019 : Luxembourg, Luxembourg)
9783030420512 (electronic bk.)




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Characterization of nanoencapsulated food ingredients

9780128156681 (electronic bk.)




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Bacteriophages : biology, technology, therapy

9783319405988 electronic book




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Advances in cyanobacterial biology

9780128193129 (electronic bk.)




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Averages of unlabeled networks: Geometric characterization and asymptotic behavior

Eric D. Kolaczyk, Lizhen Lin, Steven Rosenberg, Jackson Walters, Jie Xu.

Source: The Annals of Statistics, Volume 48, Number 1, 514--538.

Abstract:
It is becoming increasingly common to see large collections of network data objects, that is, data sets in which a network is viewed as a fundamental unit of observation. As a result, there is a pressing need to develop network-based analogues of even many of the most basic tools already standard for scalar and vector data. In this paper, our focus is on averages of unlabeled, undirected networks with edge weights. Specifically, we (i) characterize a certain notion of the space of all such networks, (ii) describe key topological and geometric properties of this space relevant to doing probability and statistics thereupon, and (iii) use these properties to establish the asymptotic behavior of a generalized notion of an empirical mean under sampling from a distribution supported on this space. Our results rely on a combination of tools from geometry, probability theory and statistical shape analysis. In particular, the lack of vertex labeling necessitates working with a quotient space modding out permutations of labels. This results in a nontrivial geometry for the space of unlabeled networks, which in turn is found to have important implications on the types of probabilistic and statistical results that may be obtained and the techniques needed to obtain them.




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Projected spline estimation of the nonparametric function in high-dimensional partially linear models for massive data

Heng Lian, Kaifeng Zhao, Shaogao Lv.

Source: The Annals of Statistics, Volume 47, Number 5, 2922--2949.

Abstract:
In this paper, we consider the local asymptotics of the nonparametric function in a partially linear model, within the framework of the divide-and-conquer estimation. Unlike the fixed-dimensional setting in which the parametric part does not affect the nonparametric part, the high-dimensional setting makes the issue more complicated. In particular, when a sparsity-inducing penalty such as lasso is used to make the estimation of the linear part feasible, the bias introduced will propagate to the nonparametric part. We propose a novel approach for estimation of the nonparametric function and establish the local asymptotics of the estimator. The result is useful for massive data with possibly different linear coefficients in each subpopulation but common nonparametric function. Some numerical illustrations are also presented.




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A hidden Markov model approach to characterizing the photo-switching behavior of fluorophores

Lekha Patel, Nils Gustafsson, Yu Lin, Raimund Ober, Ricardo Henriques, Edward Cohen.

Source: The Annals of Applied Statistics, Volume 13, Number 3, 1397--1429.

Abstract:
Fluorescing molecules (fluorophores) that stochastically switch between photon-emitting and dark states underpin some of the most celebrated advancements in super-resolution microscopy. While this stochastic behavior has been heavily exploited, full characterization of the underlying models can potentially drive forward further imaging methodologies. Under the assumption that fluorophores move between fluorescing and dark states as continuous time Markov processes, the goal is to use a sequence of images to select a model and estimate the transition rates. We use a hidden Markov model to relate the observed discrete time signal to the hidden continuous time process. With imaging involving several repeat exposures of the fluorophore, we show the observed signal depends on both the current and past states of the hidden process, producing emission probabilities that depend on the transition rate parameters to be estimated. To tackle this unusual coupling of the transition and emission probabilities, we conceive transmission (transition-emission) matrices that capture all dependencies of the model. We provide a scheme of computing these matrices and adapt the forward-backward algorithm to compute a likelihood which is readily optimized to provide rate estimates. When confronted with several model proposals, combining this procedure with the Bayesian Information Criterion provides accurate model selection.




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Estimating the number of connected components in a graph via subgraph sampling

Jason M. Klusowski, Yihong Wu.

Source: Bernoulli, Volume 26, Number 3, 1635--1664.

Abstract:
Learning properties of large graphs from samples has been an important problem in statistical network analysis since the early work of Goodman ( Ann. Math. Stat. 20 (1949) 572–579) and Frank ( Scand. J. Stat. 5 (1978) 177–188). We revisit a problem formulated by Frank ( Scand. J. Stat. 5 (1978) 177–188) of estimating the number of connected components in a large graph based on the subgraph sampling model, in which we randomly sample a subset of the vertices and observe the induced subgraph. The key question is whether accurate estimation is achievable in the sublinear regime where only a vanishing fraction of the vertices are sampled. We show that it is impossible if the parent graph is allowed to contain high-degree vertices or long induced cycles. For the class of chordal graphs, where induced cycles of length four or above are forbidden, we characterize the optimal sample complexity within constant factors and construct linear-time estimators that provably achieve these bounds. This significantly expands the scope of previous results which have focused on unbiased estimators and special classes of graphs such as forests or cliques. Both the construction and the analysis of the proposed methodology rely on combinatorial properties of chordal graphs and identities of induced subgraph counts. They, in turn, also play a key role in proving minimax lower bounds based on construction of random instances of graphs with matching structures of small subgraphs.




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A characterization of the finiteness of perpetual integrals of Lévy processes

Martin Kolb, Mladen Savov.

Source: Bernoulli, Volume 26, Number 2, 1453--1472.

Abstract:
We derive a criterium for the almost sure finiteness of perpetual integrals of Lévy processes for a class of real functions including all continuous functions and for general one-dimensional Lévy processes that drifts to plus infinity. This generalizes previous work of Döring and Kyprianou, who considered Lévy processes having a local time, leaving the general case as an open problem. It turns out, that the criterium in the general situation simplifies significantly in the situation, where the process has a local time, but we also demonstrate that in general our criterium can not be reduced. This answers an open problem posed in ( J. Theoret. Probab. 29 (2016) 1192–1198).




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Characterization of probability distribution convergence in Wasserstein distance by $L^{p}$-quantization error function

Yating Liu, Gilles Pagès.

Source: Bernoulli, Volume 26, Number 2, 1171--1204.

Abstract:
We establish conditions to characterize probability measures by their $L^{p}$-quantization error functions in both $mathbb{R}^{d}$ and Hilbert settings. This characterization is two-fold: static (identity of two distributions) and dynamic (convergence for the $L^{p}$-Wasserstein distance). We first propose a criterion on the quantization level $N$, valid for any norm on $mathbb{R}^{d}$ and any order $p$ based on a geometrical approach involving the Voronoï diagram. Then, we prove that in the $L^{2}$-case on a (separable) Hilbert space, the condition on the level $N$ can be reduced to $N=2$, which is optimal. More quantization based characterization cases in dimension 1 and a discussion of the completeness of a distance defined by the quantization error function can be found at the end of this paper.




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The fourth characteristic of a semimartingale

Alexander Schnurr.

Source: Bernoulli, Volume 26, Number 1, 642--663.

Abstract:
We extend the class of semimartingales in a natural way. This allows us to incorporate processes having paths that leave the state space $mathbb{R}^{d}$. In particular, Markov processes related to sub-Markovian kernels, but also non-Markovian processes with path-dependent behavior. By carefully distinguishing between two killing states, we are able to introduce a fourth semimartingale characteristic which generalizes the fourth part of the Lévy quadruple. Using the probabilistic symbol, we analyze the close relationship between the generators of certain Markov processes with killing and their (now four) semimartingale characteristics.




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Almost 12,000 meatpacking and food plant workers have reportedly contracted COVID-19. At least 48 have died.

The infections and deaths are spread across roughly two farms and 189 meat and processed food factories.





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Spatial Disease Mapping Using Directed Acyclic Graph Auto-Regressive (DAGAR) Models

Abhirup Datta, Sudipto Banerjee, James S. Hodges, Leiwen Gao.

Source: Bayesian Analysis, Volume 14, Number 4, 1221--1244.

Abstract:
Hierarchical models for regionally aggregated disease incidence data commonly involve region specific latent random effects that are modeled jointly as having a multivariate Gaussian distribution. The covariance or precision matrix incorporates the spatial dependence between the regions. Common choices for the precision matrix include the widely used ICAR model, which is singular, and its nonsingular extension which lacks interpretability. We propose a new parametric model for the precision matrix based on a directed acyclic graph (DAG) representation of the spatial dependence. Our model guarantees positive definiteness and, hence, in addition to being a valid prior for regional spatially correlated random effects, can also directly model the outcome from dependent data like images and networks. Theoretical results establish a link between the parameters in our model and the variance and covariances of the random effects. Simulation studies demonstrate that the improved interpretability of our model reaps benefits in terms of accurately recovering the latent spatial random effects as well as for inference on the spatial covariance parameters. Under modest spatial correlation, our model far outperforms the CAR models, while the performances are similar when the spatial correlation is strong. We also assess sensitivity to the choice of the ordering in the DAG construction using theoretical and empirical results which testify to the robustness of our model. We also present a large-scale public health application demonstrating the competitive performance of the model.




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A Bayesian Approach to Statistical Shape Analysis via the Projected Normal Distribution

Luis Gutiérrez, Eduardo Gutiérrez-Peña, Ramsés H. Mena.

Source: Bayesian Analysis, Volume 14, Number 2, 427--447.

Abstract:
This work presents a Bayesian predictive approach to statistical shape analysis. A modeling strategy that starts with a Gaussian distribution on the configuration space, and then removes the effects of location, rotation and scale, is studied. This boils down to an application of the projected normal distribution to model the configurations in the shape space, which together with certain identifiability constraints, facilitates parameter interpretation. Having better control over the parameters allows us to generalize the model to a regression setting where the effect of predictors on shapes can be considered. The methodology is illustrated and tested using both simulated scenarios and a real data set concerning eight anatomical landmarks on a sagittal plane of the corpus callosum in patients with autism and in a group of controls.




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The Pain of Sleep Loss: A Brain Characterization in Humans

Adam J. Krause
Mar 20, 2019; 39:2291-2300
BehavioralSystemsCognitive




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Dendritic spines of CA 1 pyramidal cells in the rat hippocampus: serial electron microscopy with reference to their biophysical characteristics

KM Harris
Aug 1, 1989; 9:2982-2997
Articles




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Wintrust Financial Corporation Announces Precautionary Decision to Help Achieve Community Health Objectives By Temporarily Closing Selected Branches

To view more press releases, please visit http://www.snl.com/irweblinkx/news.aspx?iid=1024452.