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Chennai: Don’t just wear masks, flaunt it too

Chennai: Don’t just wear masks, flaunt it too




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Cops to tread cautiously with drunk driving tests in Hyderabad

Cops to tread cautiously with drunk driving tests in Hyderabad




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Sanitiser overuse may cause eye issues: Study

Sanitiser overuse may cause eye issues: Study




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Mumbai: No interim bail for man accused in PNB fraud

Mumbai: No interim bail for man accused in PNB fraud




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Loan defaulters flee, SBI complains after 4 yrs

Loan defaulters flee, SBI complains after 4 yrs




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Maruti confirms new S-Cross launch post-lockdown

Maruti confirms new S-Cross launch post-lockdown




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[ASAP] Dysidealactams and Dysidealactones: Sesquiterpene Glycinyl-Lactams, Imides, and Lactones from a <italic toggle="yes">Dysidea</italic> sp. Marine Sponge Collected in Southern Australia

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00041




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[ASAP] Synthesis of the 1,2,4-Thiadiazole Alkaloid Polyaurine B

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00166




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[ASAP] Kalparinol, a Salvialane (Isodaucane) Sesquiterpenoid Derived from Native Australian <italic toggle="yes">Dysphania</italic> Species That Suggests a Putative Biogenetic Link to Zerumbone

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b01039




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[ASAP] Update to Our Reader, Reviewer, and Author Communities—April 2020

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00431




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[ASAP] Antineoplastic Agents. 607. Emetine Auristatins

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00031




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[ASAP] Cytotoxic Monoterpenoid Indole Alkaloids from <italic toggle="yes">Tabernaemontana corymbosa</italic> as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00856




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[ASAP] A Grand Challenge. 3. Unbiased Phenotypic Function of Metabolites from Australia Plants <italic toggle="yes">Gloriosa superba</italic> and <italic toggle="yes">Alangium villosum</italic> against Parkinson

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00880




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Interventions for War-Related Posttraumatic Stress Disorder: Meeting Veterans Where They Are

Interview with Charles Hoge, MD, author of Interventions for War-Related Posttraumatic Stress Disorder: Meeting Veterans Where They Are




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Cognitive Behavior Therapy Augmentation of Pharmacotherapy in Pediatric Obsessive-Compulsive Disorder: The Pediatric OCD Treatment Study II (POTS II) Randomized Controlled Trial

Interview with Martin E. Franklin, PhD, author of Cognitive Behavior Therapy Augmentation of Pharmacotherapy in Pediatric Obsessive-Compulsive Disorder: The Pediatric OCD Treatment Study II (POTS II) Randomized Controlled Trial




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Neuron Number and Size in Prefrontal Cortex of Children With Autism

Interview with Eric Courchesne, PhD, author of Neuron Number and Size in Prefrontal Cortex of Children With Autism




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Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial

Interview with Jay H. Traverse, MD, author of Effect of Intracoronary Delivery of Autologous Bone Marrow Mononuclear Cells 2 to 3 Weeks Following Acute Myocardial Infarction on Left Ventricular Function: The LateTIME Randomized Trial




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Causes of Death Among Stillbirths

Interview with Robert M. Silver, MD, author of Causes of Death Among Stillbirths




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JAMA: 2012-04-11, Vol. 307, No. 14, Author Interview

Interview with Donald M. Berwick, MD, MPP, author of Eliminating Waste in US Health Care




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Association Between Helicopter vs Ground Emergency Medical Services and Survival for Adults With Major Trauma

Interview with Samuel M. Galvagno Jr, DO, PhD, author of Association Between Helicopter vs Ground Emergency Medical Services and Survival for Adults With Major Trauma




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Epidemiology of Staphylococcus aureus Blood and Skin and Soft Tissue Infections in the US Military Health System, 2005-2010

Interview with Clinton K. Murray, MD, author of Epidemiology of Staphylococcus aureus Blood and Skin and Soft Tissue Infections in the US Military Health System, 2005-2010




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Prevalence of and Risk Factors for Autopsy-Determined Atherosclerosis Among US Service Members, 2001-2011

Interview with Bryant J. Webber, MD, author of Prevalence of and Risk Factors for Autopsy-Determined Atherosclerosis Among US Service Members, 2001-2011




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Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories: A Systematic Review and Meta-analysis

Interview with Katherine M. Flegal, PhD, author of Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories: A Systematic Review and Meta-analysis




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Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children

Interview with Pål Surén, author of Association Between Maternal Use of Folic Acid Supplements and Risk of Autism Spectrum Disorders in Children




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay

Interview with Atul A. Gawande, MD, MPH, author of Relationship Between Occurrence of Surgical Complications and Hospital Finances, and Uwe E. Reinhardt, PhD, author of Making Surgical Complications Pay




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Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism

Interview with Jakob Christensen, PhD, author of Prenatal Valproate Exposure and Risk of Autism Spectrum Disorders and Childhood Autism




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Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women's Health Initiative Randomized Trials

Interview with JoAnn E. Manson, MD, author of Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women's Health Initiative Randomized Trials




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The Familial Risk of Autism

Interview with Sven Sandin, MSc, author of The Familial Risk of Autism




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The Pathophysiology and Treatment of Glaucoma

Interview with Robert N. Weinreb, MD, author of The Pathophysiology and Treatment of Glaucoma




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Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes

Interview with Christianne L. Roumie, MD, MPH, author of Association Between Intensification of Metformin Treatment With Insulin vs Sulfonylureas and Cardiovascular Events and All-Cause Mortality Among Patients With Diabetes




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of Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury: A Randomized Clinical Trial

Interview with Claudia S. Robertson, MD, author of Effect of Erythropoietin and Transfusion Threshold on Neurological Recovery After Traumatic Brain Injury: A Randomized Clinical Trial




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Maternal Diabetes and Autism in Offspring

Interview with Anny H. Xiang, PhD, author of Association of Maternal Diabetes With Autism in Offspring




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Autism Occurrence by MMR Vaccine Status Among US Children

Interview with Anjali Jain, MD, author of Autism Occurrence by MMR Vaccine Status Among US Children With Older Siblings With and Without Autism




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Posttraumatic Stress Disorder

Edward H. Livingston, MD, interviews a war veteran and discusses PTSD with Maria Steenkamp, PhD, author of Psychotherapy for Military-Related PTSD, and Michele Spoont, PhD, author of Rational Clinical Exam: Does This Patient Have Posttraumatic Stress Disorder? The article by Dr Steenkamp reports that many military personnel and veterans with posttraumatic stress disorder achieve clinically meaningful improvement with use of the first-line trauma-focused interventions cognitive processing therapy and prolonged exposure.
 The Rational Clinical Examination Systematic Review by Dr Spoont examines the utility of self-report screening instruments for posttraumatic stress disorder among primary care and high-risk populations.





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Head Trauma

Minor head trauma usually does not cause significant brain injury. To be safe, clinicians often obtain head CT scans to ensure no major injury is present. For minor head trauma (Glascow coma scale 13-15), the risk to benefit ratio for head CT is usually not in favor of getting CT scans. When the Canadian head CT rule or New Orleans Criteria are negative, there is a very small risk for missing a significant brain injury. Joshua Easter, MD from the Department of Emergency Medicine at the University of Virginia who authored a JAMA Rational Clinical Examination article on this topic is interviewed as is Frederick Rivara, from the Department of Pediatrics at the University of Washington who wrote an accompanying editorial. Michelle Mello, a Law Professor at Stanford, discusses the medical liability associated with not obtaining neuroimaging for minor head trauma.







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Treatments for Hyperemesis and Nausea and Vomiting in Pregnancy

Nearly all women experience some element of nausea and vomiting during their pregnancies. In this podcast we review the entire spectrum of disease all the way up to hyperemesis gravidarum and how to provide care for women experiencing these problems.

Article discussed in this episode:

Treatments for Hyperemesis Gravidarum and Nausea and Vomiting in Pregnancy

 









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The 2019 Novel Coronavirus Outbreak – Update From NIAID’s Anthony Fauci, MD

In February 2020 the nature of the 2019-nCoV outbreak is still slowly coming into focus but it appears to be acting more like bad pandemic influenza (efficient spread, overall lower mortality) than like SARS (less efficient spread, overall higher mortality). Anthony Fauci, MD, of the US National Institute of Allergy and Infectious Diseases (NIAID) discusses the latest developments with JAMA Editor in Chief Howard Bauchner.

Coronavirus Resource Center




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JAMA Author Interviews Becomes “Conversations with Dr Bauchner”

JAMA Author Interviews is taking on a new look! Be sure to subscribe to Conversations with Dr Bauchner, a podcast that features the same insightful interviews with leading researchers and thinkers in health care. Covering a broad range of practice-changing research and important innovations, Conversations with Dr Bauchner is a convenient way to stay current with the most pressing issues facing medicine and healthcare. Listen and subscribe at jamanetworkaudio.com.




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COVID-19 Update With NIAID's Anthony Fauci, MD; March 6, 2020

Coronavirus testing, mortality, vaccine development, containment vs mitigation, and more. JAMA Editor Howard Bauchner, MD, interviews US NIAID Director Anthony Fauci, MD, about the latest developments in SARS-CoV-2 science and global spread of infection.

JAMA Coronavirus Resource Page




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COVID-19 Update with NIAID’s Anthony Fauci, MD; March 18, 2020

Diagnostic testing, NSAIDs, ACE Inhibitors, antivirals, and more. Anthony Fauci, MD from NIAID discusses latest developments in the spread and clinical management of COVID-19 and the SARS-CoV-2 virus with JAMA Editor Howard Bauchner, MD.

JAMA Coronavirus Resource Center