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Dynamics of periphery: atlas for emerging creative and resilient habitats / edited by Jörg Schröder, Maurizio Carta, Maddalena Ferretti, Barabara Lino

Rotch Library - HT371.D963 2018




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[ASAP] Combined Application of Albumin-Binding [<sup>177</sup>Lu]Lu-PSMA-ALB-56 and Fast-Cleared PSMA Inhibitors: Optimization of the Pharmacokinetics

Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.0c00199




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[ASAP] Surfactin Ameliorated the Internalization and Inhibitory Performances of Bleomycin Family Compounds in Tumor Cells

Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.0c00281




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[ASAP] Discovery and Optimization of Triazine Nitrile Inhibitors of <italic toggle="yes">Toxoplasma gondii</italic> Cathepsin L for the Potential Treatment of Chronic Toxoplasmosis in the CNS

ACS Chemical Neuroscience
DOI: 10.1021/acschemneuro.9b00674




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[ASAP] Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24

ACS Chemical Neuroscience
DOI: 10.1021/acschemneuro.0c00042




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[ASAP] Neuronal Calcium Sensor GCAP1 Encoded by <italic toggle="yes">GUCA1A</italic> Exhibits Heterogeneous Functional Properties in Two Cases of Retinitis Pigmentosa

ACS Chemical Neuroscience
DOI: 10.1021/acschemneuro.0c00111




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Punjab prohibits sale of uniform, books in schools

Punjab has prohibited the sale of uniforms and textbooks in school premises, state Education Minister Inder Singla said on Saturday.




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[ASAP] Metal-Free Colorimetric Detection of Pyrophosphate Ions by Inhibitive Nanozymatic Carbon Dots

ACS Sensors
DOI: 10.1021/acssensors.9b02486




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Two bit circus and the future of entertainment / Elise Lemle ... [and others]

Online Resource




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Global perspectives on adult education and learning policy / edited by Marcella Milana, Tom Nesbit

Online Resource




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Art, education and gender: the shaping of female ambition / Gill Hopper, University of Reading, UK

Online Resource




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Global perspectives on adult education and learning policy / edited by Marcella Milana, Tom Nesbit

Online Resource




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Crosslinked fluoropolymers exhibiting superior high-temperature energy density and charge–discharge efficiency

Energy Environ. Sci., 2020, 13,1279-1286
DOI: 10.1039/C9EE03603B, Paper
He Li, Matthew R. Gadinski, Yuqi Huang, Lulu Ren, Yao Zhou, Ding Ai, Zhubing Han, Bin Yao, Qing Wang
Superior high-temperature discharged energy densities in comparison to those of the current dielectric polymers have been demonstrated in the crosslinked fluoropolymers.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Continuous flow synthesis of the URAT1 inhibitor lesinurad

React. Chem. Eng., 2020, 5,865-872
DOI: 10.1039/C9RE00483A, Paper
Mariana C. F. C. B. Damião, Henrique M. Marçon, Julio Cezar Pastre
A 5-steps continuous flow synthesis of lesinurad is provided and delivers this API in 68% overall yield.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bank of England sees worst slump in 300 years as coronavirus bites

The BoE said Britain's economy might be on course to shrink by 25% in the three months to June and unemployment could more than double to 9% of the workforce




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Seaweed Porphyra yezoensis polysaccharides with different molecular weights inhibit hydroxyapatite damage and osteoblast differentiation of A7R5 cells

Food Funct., 2020, 11,3393-3409
DOI: 10.1039/C9FO01732A, Paper
Ling-Hong Huang, Hong Liu, Jia-Yun Chen, Xin-Yuan Sun, Zhi-hui Yao, Jin Han, Jian-Ming Ouyang
Porphyra yezoensis polysaccharide could effectively reduce the cell damage and osteogenic transformation of vascular smooth muscle cells induced by hydroxyapatite crystals.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Preparation of theasinensin A and theasinensin B and exploration of their inhibitory mechanism on α-glucosidase

Food Funct., 2020, 11,3527-3538
DOI: 10.1039/C9FO03054A, Paper
Sainan Tao, Guijie Chen, Weiqi Xu, Yujia Peng, Peng Wan, Yi Sun, Xiaoxiong Zeng, Zhonghua Liu
Theasinensin A (TSA) and theasinensin B (TSB), dimers of tea catechins produced during the processing of oolong tea and black tea, had superior inhibitory effects on α-glucosidase.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Oleacein inhibits STAT3, activates the apoptotic machinery, and exerts anti-metastatic effects in the SH-SY5Y human neuroblastoma cells

Food Funct., 2020, 11,3271-3279
DOI: 10.1039/D0FO00089B, Paper
Santa Cirmi, Marilena Celano, Giovanni Enrico Lombardo, Valentina Maggisano, Antonio Procopio, Diego Russo, Michele Navarra
The present findings demonstrate that oleacein, the main secoiridoid of extravirgin olive oil, acts against neuroblastoma cells, by reducing cell adhesion and migration, inducing apoptotic death and modulating STAT3-dependent pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Addition of flavonols and polysaccharides as excipient ingredients into epicatechin rich green tea extract inhibited free radical formation and glucose uptake

Food Funct., 2020, 11,3105-3111
DOI: 10.1039/C9FO03020D, Paper
So-Hee Yoo, Yeong-Eun Lee, Jin-Oh Chung, Chan-Su Rha, Yong-Deog Hong, Mi-Young Park, Soon-Mi Shim
Results from the current study suggested that whole green tea components rich in flavonols and polysaccharides could be potential hypoglycemic excipient ingredients into green tea catechins by enhancing catechin absorption.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Dietary intake of Lycium ruthenicum Murray ethanol extract inhibits colonic inflammation in dextran sulfate sodium-induced murine experimental colitis

Food Funct., 2020, 11,2924-2937
DOI: 10.1039/D0FO00172D, Paper
Shuai Zong, Liu Yang, Hyun Jin Park, Jinglei Li
Lycium ruthenicum Murray extract protected experimental colitis by inhibiting pro-inflammatory cytokines production, inflammatory cell infiltration, inflammatory mediators activation and oxidative stress, and restored intestinal barrier integrity.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Ergosterol peroxide from Pleurotus ferulae inhibits gastrointestinal tumor cell growth through induction of apoptosis via reactive oxygen species and endoplasmic reticulum stress

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02454A, Paper
Yi Yang, Xiaoyu Luo, Mayila Yasheng, Jun Zhao, Jinyu Li, Jinyao Li
Ergosterol peroxide was purified from Pleurotus ferulae by silica gel chromatography, Sephadex LH-20 chromatography and recrystallization and named as PFEP, which was identified by ESI-MS and NMR.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




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tert-Butyl-p-benzoquinone induces autophagy by inhibiting the Akt/mTOR signaling pathway in RAW 264.7 cells

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00281J, Paper
Xianghe Meng, Chaosheng Xia, Qin Ye, Xiaohua Nie
Autophagy mediate by p53/Akt/mTOR signaling was linked to overproduction of ROS by tert-butyl-p-benzoquinone.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Usage of supercritical fluid techniques to obtain bioactive alkaloid-rich extracts from cherimoya peel and leaves: extract profiles and their correlation with antioxidant properties and acetylcholinesterase and α-glucosidase inhibitory activities

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00342E, Paper
Oscar Galarce-Bustos, Mª Teresa Fernández-Ponce, Antonio Montes, Clara Pereyra, Lourdes Casas, Casimiro Mantell, Mario Aranda
The wastes generated by cherimoya cultivation and processing industries should be contemplated as a valuable source of bioactive alkaloids, with potential in pharmaceutical applications for the treatment or prevention of chronic diseases.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Bergaptol from blossoms of Citrus aurantium L. var. amara Engl inhibits LPS-induced inflammatory responses and ox-LDL-induced lipid deposition

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO00255C, Paper
Chun-Yan Shen, Tian-Xing Wang, Jian-Guo Jiang, Chun-Ling Huang, Wei Zhu
Aberrant activation of inflammation and excess accumulation of lipids play pivotal roles in atherosclerosis (AS) progression. Constituents from Citrus aurantium Linn variant amara Engl (CAVA) were effectively investigated for their...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Red ginseng protects against cisplatin-induced intestinal toxicity by inhibiting apoptosis and autophagy via the PI3K/AKT and MAPK signaling pathways

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00469C, Paper
Jun-jie Zhang, Jian-qiang Wang, Xing-yue Xu, Jia-yu Yang, Zi Wang, Shuang Jiang, Ying-ping Wang, Jing Zhang, Rui Zhang, Wei Li
Although growing evidence has shown that ginseng (Panax ginseng C.A. Meyer.) exerts strong protective and preventive effects on cisplatin-induced side effects, the ameliorative effects of ginseng on intestinal damage caused by cisplatin are unknown to date.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Production of GABA-enriched idli with ACE inhibitory and antioxidant properties using Aspergillus oryzae: the antihypertensive effects in spontaneously hypertensive rats

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02854D, Paper
Mohsen Zareian, Ehsan Oskoueian, Marjan Majdinasab, Bita Forghani
The present study aimed to develop a fermented food (idli) with enhanced γ-aminobutyric acid (GABA) and angiotensin I-converting enzyme (ACE) inhibitory properties using a GABA-producing fungus.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02602A, Paper
Chu-Wen Li, Min-Zhen Deng, Zhi-Jie Gao, Yuan-Ye Dang, Guo-Dong Zheng, Xiu-Juan Yang, Ying-Xin Chao, Ye-Feng Cai, Xiao-Li Wu
The metabolite of ginsenosides, compound K improves memory and cognitive dysfunction in diabetes mellitus mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Ricciardo expects a bit of chaos when F1 returns

Ricciardo expects a bit of chaos when F1 returns




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BAML sees platinum, palladium deficit this year as South Africa production losses bite

BAML sees platinum, palladium deficit this year as South Africa production losses bite




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US labor market shatters post World War 2 records as coronavirus lockdowns bite

US labor market shatters post World War 2 records as coronavirus lockdowns bite




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Sal forest tortoise habitat stretches over unprotected areas

Protected areas are designated in a largely mammal-centric way, many equally threatened reptiles and amphibians live outside these




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[ASAP] PTP1B-Inhibiting Branched-Chain Fatty Acid Dimers from <italic toggle="yes">Eremophila oppositifolia</italic> subsp. <italic toggle="yes">angustifolia</italic> Identified by High-Resolution PTP1B Inhibiti

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00070




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[ASAP] Spongian Diterpenoids Derived from the Antarctic Sponge <italic toggle="yes">Dendrilla antarctica</italic> Are Potent Inhibitors of the <italic toggle="yes">Leishmania</italic> Parasite

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00025




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[ASAP] Naphthacemycins from a <italic toggle="yes">Streptomyces</italic> sp. as Protein-Tyrosine Phosphatase Inhibitors

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00417




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[ASAP] Diisonitrile-Mediated Reactive Oxygen Species Accumulation Leads to Bacterial Growth Inhibition

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00125




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[ASAP] Aromatic Esters of the Crinane Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Butyrylcholinesterase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00561




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[ASAP] Phenylpropanoid-Conjugated Triterpenoids from the Leaves of <italic toggle="yes">Actinidia arguta</italic> and Their Inhibitory Activity on a-Glucosidase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00643




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[ASAP] Cyperane-Type and Related (Nor)Sesquiterpenoids from the Root Bark of <italic toggle="yes">Acanthopanax gracilistylus</italic> and Their Inhibitory Effects on Nitric Oxide Production

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00913




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[ASAP] Phaeosphaones: Tyrosinase Inhibitory Thiodiketopiperazines from an Endophytic <italic toggle="yes">Phaeosphaeria fuckelii</italic>

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00046




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[ASAP] Cytotoxic Monoterpenoid Indole Alkaloids from <italic toggle="yes">Tabernaemontana corymbosa</italic> as Potent Autophagy Inhibitors by the Attenuation of Lysosomal Acidification

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00856




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[ASAP] Cucurbitane-Type Triterpenoids from the Vines of <italic toggle="yes">Momordica charantia</italic> and Their Anti-inflammatory Activities

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.9b00592




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[ASAP] Structural Specificity of Flavonoids in the Inhibition of Human Fructose 1,6-Bisphosphatase

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00014




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[ASAP] Inhibitory Effect of Cannabidiol on the Activation of NLRP3 Inflammasome Is Associated with Its Modulation of the P2X7 Receptor in Human Monocytes

Journal of Natural Products
DOI: 10.1021/acs.jnatprod.0c00138




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Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial

Interview with Steven E. Nissen, MD, author of Effects of the CETP Inhibitor Evacetrapib Administered as Monotherapy or in Combination With Statins on HDL and LDL Cholesterol: A Randomized Controlled Trial





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Pioneering Geneticist Explains Ambitious Plan to “Write” the Human Genome

This Medical News podcast discusses the Human Genome Project-write with Harvard geneticist, George Church, PhD.




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Soil physics with Python : transport in the soil-plant-atmosphere system / Marco Bittelli, Gaylon S. Campbell, Fausto Tomei

Bittelli, Marco, author




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The status of kangaroos and wallabies in Australia / report of a Working Group on Macropod Habitat of the Standing Committee of the Council of Nature Conservation Ministers ; edited by Dr. A.A. Burbidge

Council of Nature Conservation Ministers (Australia). Working Group on Macropod Habitat




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Guidelines on urban and peri-urban forestry / by Fabio Salbitano, Simone Borelli, Michela Conigliaro, Yujuan Chen

Salbitano, Fabio, author