A hybrid concrete saw includes a saw blade, an internal combustion engine having an output shaft operably connected to the saw blade, and an electric motor connectable to a battery for receiving power therefrom and having an output shaft operably connected to the saw blade. A transmission is connected to the output shaft of each of the engine and the electric motor and the saw blade. A clutch selectively decouples one of the engine and the electric motor from the transmission. A controller controls operation of the engine and the electric motor. The concrete saw is operable in a first mode where the saw blade is driven solely by the engine, a second mode where the saw blade is driven solely by the electric motor, and a third mode where the saw blade is driven by both the engine and the electric motor.

A saw apparatus for sawing paving slabs has a frame mounted on a ground contacting propulsion member such that the frame may move above a slab to be cut without touching the slab. A first saw support assembly disposes a blade of a saw in cutting engagement with the slab for a transverse cut. A second saw support assembly disposes a blade of another saw in cutting engagement with the slab for a longitudinal cut. The saws are mounted on the saw assemblies and the saw assemblies are mounted on the frame and the frame is mounted on the ground contact propulsion members such that no part of said frame need contact the slab during cutting.

A novel cutting method and apparatus includes a cutting blade adapted to consistently and easily form a desirable kerf in a concrete substrate while capturing substantially all resulting concrete dust.

The invention relates to improved bitumen recovery processes and systems. One process provides for operation of a bitumen froth treatment plant at optimum shear rates in the feed pipe carrying the bitumen froth to the froth settling unit. Another process provides for optimizing the design of a bitumen froth treatment plant by optimizing the diameter of the feed pipe to impart an optimum shear rate to the bitumen froth mixture and further optimizing the volume of the feed pipe to impart an optimum residence time for the bitumen froth stream in the feed pipe. An optimal plant design is also disclosed, the plant including optimal diameter and volume of the feed pipe.

A device for processing a hydrocarbon resource may include a hydrocarbon processing container configured to receive the hydrocarbon resource therein and having a pair of opposing ends with an enlarged width medial portion therebetween. The device may also a spirally wound electrical conductor surrounding the hydrocarbon processing container, and a radio frequency (RF) circuit coupled to the spirally wound electrical conductor and configured to supply RF power to the hydrocarbon resource while tracking a load resonance of the RF circuit. The RF circuit may be configured to generate magnetic fields within the hydrocarbon processing container parallel with an axis thereof.

A method is described to excite molecules at their natural resonance frequencies with sufficient energy to break or form chemical bonds using electromagnetic radiation in the radio frequency (RF) and microwave frequency range. Liquid, solid, or gaseous materials are prepared and injected into a resonant structure where they are bombarded with electromagnetic energy in the RF or microwave range at resonant frequencies of the molecules of the materials. Alternatively, electromagnetic energy tuned to dielectric particles prepared from the materials may also be supplied to further enhance the reaction.

A device for processing a hydrocarbon resource may include a hydrocarbon processing container configured to receive the hydrocarbon resource therein and having a pair of opposing ends with an enlarged width medial portion therebetween. The device may also include a radio frequency (RF) source, and a first spirally wound electrical conductor surrounding the hydrocarbon processing container and coupled to the RF source. The device may further include a second spirally wound electrical conductor carried within the hydrocarbon processing container. The first spirally wound electrical conductor may be configured to generate magnetic fields with the hydrocarbon processing container that are parallel with an axis thereof.

A device for processing a hydrocarbon resource may include a hydrocarbon processing container configured to receive the hydrocarbon resource therein and having a pair of opposing ends with an enlarged width medial portion therebetween. The device may also include a radio frequency (RF) source, and a spirally wound electrical conductor surrounding the hydrocarbon processing container and coupled to the RF source. The spirally wound electrical conductor may be configured to generate magnetic fields within the hydrocarbon processing container that are parallel with an axis thereof.

A knit apparel is made using a decorating pattern that is generated to give the apparel the appearance of tie dyed apparel. The decorating pattern includes a main element, a secondary element and intermediate zones have the same color but gradually lighter shades as the main element.

Described are methods, implants, insertion tools, and related systems and kits, for placing an implant to treat urinary incontinence; the implants include soft tissue anchors that are capable of engaging needles of the insertion tools, and the implants are designed to place a central support portion at a location to support a urethra with extension portions and soft tissue anchors extending to tissue at regions of an obturator foramen.

A method for manufacturing a fluid-filled chamber may include obtaining a spacer textile material a stabilization structure. A tensile member is removed from an area of the spacer textile material where the stabilizing structure is absent. The tensile member is located between a first polymer element and a second polymer element. Additionally, (a) the first layer is bonded to the first polymer element, (b) the second layer is bonded to the second polymer element, and (c) the first polymer element and the second polymer element are bonded together around a periphery of the tensile member.

A knit fabric having a modified knit structure, having a front layer of knit fabric and a back layer of knit fabric, wherein the front layer and back layer are joined together by rows of tuck stitches formed from a yarn having no more than 3% elongation and wherein the knit fabric is puncture resistant, and optionally cut and/or abrasion resistant, and a protective garment made therefrom.

An article of footwear including a full monofilament upper is described. The full monofilament upper incorporates a knitted component including a monofilament knit element. The monofilament knit element is formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures.

An article of footwear including a knitted component having a monofilament knit element with peripheral knit portions is described. The knitted component includes a monofilament knit element formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures.

An article of footwear including a full monofilament upper is described. The full monofilament upper incorporates a knitted component including a monofilament knit element. The monofilament knit element is formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures. A fusible strand may be knit with the monofilament knit element. Upon heating, the fusible strand can combine and surround the monofilament strand within the monofilament knit element.

An article of footwear including a knitted component having a monofilament knit element with peripheral knit portions is described. The knitted component includes a monofilament knit element formed by knitting with a monofilament strand. The monofilament knit element is formed of unitary knit construction with the remaining portions of the knitted component, including peripheral portions that are knit using a natural or synthetic twisted fiber yarn. An inlaid tensile element can extend through the knitted component, including portions of the monofilament knit element. The monofilament knit element may be knitted with a monofilament strand according to a variety of knit structures.

Described are methods, implants, insertion tools, and related systems and kits, for placing an implant to treat urinary incontinence; the implants include soft tissue anchors that are capable of engaging needles of the insertion tools, and the implants are designed to place a central support portion at a location to support a urethra with extension portions and soft tissue anchors extending to tissue at regions of an obturator foramen.

A preservation system for storage and logistic transport of nutritional substances. The preservation system obtains information about the nutritional substance to be preserved, senses and measures the external environment to the preservation system, senses and measures the internal environment to the preservation system, senses and measures the state of the nutritional substance, and stores such information throughout the period of preservation. Using this accumulated information, the preservation system can measure, or estimate, changes in nutritional content (usually degradation) during the period of preservation. Additionally, the preservation system can use this information to dynamically modify the preservation system to minimize detrimental changes to the nutritional content of the nutritional substance, and in some cases actually improve the nutritional substance attributes.

A multi-functional electric cooker includes a heating boiler body (1) and a cover (2). The cooker also includes a rice soup collecting container (3) which is mounted between the heating boiler body (1) and the cover (2), a sealing ring (7) which is set between the rice soup collecting container (3) and the heating boiler body (1), and a rice soup sucker (6). An opening of one end of the sucker is located at the bottom of the rice soup collecting container (3) and the height of the opening is adjusted along with the amount of the rice in the heating boiler body. An opening of the other end of the sucker is located in the rice soup collecting container (3).

A peptide comprising a sequence for opening a tight junction of an epithelial surface and optionally a cell penetrating sequence; and related compositions, optionally comprising further pharmaceutical agents; and related methods.

A molecule comprising a lipid, a peptide and a linker to bind the lipid to the peptide which have specific amino acid sequence to bind to Epidermal Growth Factor Receptor (EGFR) of tumor cells, and a liposomal composition which is targeted by the molecule, and method for preparing thereof is disclosed.

The present invention relates to Chimeric Antigen Receptors (CAR) that are recombinant chimeric proteins able to redirect immune cell specificity and reactivity toward selected membrane antigens, and more particularly in which extracellular ligand binding is a scFV derived from a CD123 monoclonal antibody, conferring specific immunity against CD123 positive cells. The engineered immune cells endowed with such CARs are particularly suited for treating lymphomas and leukemia.

The present invention relates to Chimeric Antigen Receptors (CAR) that are recombinant chimeric proteins able to redirect immune cell specificity and reactivity toward selected membrane antigens, and more particularly in which extracellular ligand binding is a scFV derived from a BCMA monoclonal antibody, conferring specific immunity against BCMA positive cells. The engineered immune cells endowed with such CARs are particularly suited for treating lymphomas, multiple myeloma and leukemia.

Provided herein are compositions and methods for modifying a predetermined nucleic acid sequence. A programmable nucleoprotein molecular complex containing a polypeptide moiety and a specificity conferring nucleic acid (SCNA) which assembles in-vivo, in a target cell, and is capable of interacting with the predetermined target nucleic acid sequence is provided. The programmable nucleoprotein molecular complex is capable of specifically modifying and/or editing a target site within the target nucleic acid sequence and/or modifying the function of the target nucleic acid sequence.

Provided herein are methods for the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient the prognosis of prostate cancer progression in a patient by analyzing the gene expression in a tumor sample obtained from the patient. In particular, gene expression levels of GCOM1, MEX3D, TRPM4, ATPAF1, PTRF, GLYATL1, FLNA, OBSCN, STRA13, WHSCl, ARFGAP3, KDM2A, FAM83H, CLDN7, CNOT6, and B3GNT9 are measured. Kits containing means for the measurement of gene expression as described herein and methods for treatment of prostate cancer are also provided.

The present invention concerns cancer biomarkers. In particular, the invention concerns HGF as a biomarker for patient selection and patient prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.

A punch button (32) has a central disc (36) integral with and separable from an outer peripheral annular ring (38). The disc and ring are joined by a breakaway portion (40) of reduced thickness. A pair of peel points or pilot cuts (50 and 52) may be provided on distally opposite sides of the disc, and if so, the disc is initially separable from the ring at the peel points and then rotatable about a rotation axis perpendicular to an axis through the distally opposite pilot cuts. The punch button is formed by providing a strip of material of a first thickness, placing the strip in a die, performing an inner cut with the die and partially cutting through the strip to yield first and second subpieces joined to each other by material of a second reduced thickness, and performing an outer cut with the die and cutting all the way through the strip to yield a piece composed of the first and second subpieces providing the disc and ring. The pilot cuts are performed by the die during performance of the inner cut and to a deeper depth than the inner cut. All of the cuts are performed in a singular die step operation wherein an outer punch (58) is moved toward an inner punch (66) in one axial direction to perform the inner cut, the pilot cuts, and a portion of the outer cut, and continuing movement of the outer punch in the one direction and simultaneously moving the inner punch in the same direction in unison with the outer punch to complete the outer cut.

The present invention relates to a plant-based wrapping paper for wrapping food. The plants (raw materials) may be fruits, herbs, medicinal plants, tea, vegetables and/or spices. The invention further relates to a method for producing said wrapping paper, its use for wrapping food or its use as packaging material.

The present invention is directed to novel organoleptic compounds, a process of augmenting, enhancing or imparting taste to a material selected from the group consisting of a foodstuff, a chewing gum, a dental product, an oral hygiene product and a medicinal product comprising the step of incorporating an olfactory acceptable amount of such novel organoleptic compounds, and a process of improving, enhancing or modifying a fragrance composition through the addition of an olfactory acceptable amount of such novel organoleptic compounds.

Pancake mixes comprising at least one type of whole grain flour, at least one natural sweetener, at least one fat and a leavening system are provided herein. Packaged food products comprising single-serving containers containing said pancake mixes, as well as methods of preparing pancakes, are also provided. The pancakes described herein are preferably 100% whole grain and free from preservatives and/or artificial colorings.

This disclosure describes a simple, low cost method to produce a modular dry mix that can easily be modified and customized to produce a wide range of easy to aerate, no ice cream machine needed, ice cream and frozen dairy and non-dairy desserts and products made by this process. The method relies on successive simultaneous particle size reduction and blending steps without the use of traditional mix drying operations. The formulations produced by this process are modular and allow quick and simple ingredient substitutions to create distinct finished products. The process yields mixes that produce stronger, more stable foams that don't leave an oily mouth feel. The disclosure also includes a formulation and process used to make ice cream, and related frozen dairy and non-dairy desserts at room temperature in one step where the ingredients do not need to be aged, or homogenized, and aeration occurs without the need for simultaneous cooling or freezing. The process allows the end-user to control and vary the texture, freezing rate, melting point and eating qualities of the product without the use of traditional, home or industrial ice cream machines and a product made by this process. A product produced from this mix consists of a (protein-concentrate and emulsifier)—stabilized, protein-based foam created by combining a powder mix with one or a combination of a large range of above freezing temp liquids then immediately whisking the mixture at room temp to a target overrun without pre-aging, and then freezing that product statically till desired hardness is achieved. The main execution of this process involves the use of dry powders that are transported and sold dry and then reconstituted by the end user before they are combined without pre-treatment, freezing homogenization or aging. The manufacturing process offers significant advantages over current dry mix production methods which require significant upfront investment and produce hard to customize mixes. The formulation and finished product making portions of the invention offer significant improvement over existing manufacturing methods for frozen desserts and dessert mixes that require simultaneous freezing and aeration in terms of cost, convenience, customizability, shelf-stability and environmental impact.

A formulation consisting of a food-grade dye and a plant aroma cocktail is uptaken by plants and flowers and fruit. The improved aroma profile and color make the plant or it's flowers or it's fruit more desirable for consumption or viewing with an enhanced aroma.

It has unexpectedly been found that Pichia spp. strains have advantageous properties useful in the beer fermentation process. In particular, Pichia spp. yeast strains can be combined with normal beer yeast strains and different hop varieties in a fermentation process to produce synergistic effects—namely, the increased production of esters in the fermentation product. More specifically, the yeast can be used to produce increased levels of isoamyl acetate, isobutyl acetate, ethyl propionate, ethyl valerate, ethyl butyrate, ethyl decanoate and ethyl octanoate in beer. In addition, the Pichia spp. strain interacts differently with different hop varieties, so the flavor profile of beer can be tuned by using different combinations of Pichia spp. strains and hops. The present invention relates to a method of brewing beer using a Pichia spp. yeast strain and at least one hop variety, a beer obtainable by such a method and use of a Pichia spp. yeast strain according to the present invention.

A pass-thru ratchet wrench includes a wrench body. A front end of the wrench body has a head portion. A ratchet is provided in the head portion. The ratchet has a receiving hole to receive a socket. The ratchet has a first neck portion at an upper edge thereof and an annular groove around the outer wall of the first neck portion. The annular groove has a certain depth. The ratchet has a plurality of through holes in annular groove. A C-shaped buckle ring is disposed in the annular groove. The C-shaped buckle ring extends out of the through holes to form a limit portion. The limit portion is adapted to stop the socket, thereby the receiving hole of the ratchet can limit the socket from displacing.

A powered ratchet drive for a ratchet wrench includes a pair of elongate pawls for driving an output member of the wrench. Each pawl may have a lower portion pivotally attached to a rocker and an upper portion comprising teeth for engagement with teeth of the output member to turn the output member. The upper portion of the pawl extends outward at an angle with respect to the lower portion. The ratchet may include a compression spring secured inside a cavity of each pawl for biasing the pawl into engagement with the output member. The ratchet also includes a reversing switch mechanism for selectively configuring the ratchet in a forward-driving configuration and in a reverse-driving configuration. The switch mechanism includes a cam disposed between the pawls. The cam has a groove for receiving one of the pawls during operation depending on the configuration of the ratchet.

A ratchet wrench includes a reception hole defined through the function end of the wrench and a recess is defined in the inner periphery of the reception hole. A ratchet wheel is rotatably located in the reception hole. A pawl, a restriction member and a resilient member are received in the recess. The two ends of the resilient member respectively contact the pawl and the restriction member to bias the pawl to be engaged with the ratchet wheel. A restriction ring is located in the reception hole and has a rod extending therefrom, the rod extends into the recess. The restriction member is located between the rod and the inner periphery of the recess.

A geared socket wrench hand tool is disclosed. The socket wrench is a clickless wrench allowing for more precise movement of the socket. The socket wrench, through a series of gears, can rotate in infinitesimally small rotations.

A torque wrench equipped with a cam-type torque detection mechanism is provided which is capable of detecting a torque with high accuracy, providing a non-unusual-feeling of handle operation after torque has been detected, and enabling tightening of fastened members such as bolts with safety. In a torque wrench equipped with the cam-type torque detection mechanism, a cam portion 27 formed on the outer circumference of a tubular cam 22 includes: a static engagement cam surface 27a with which a roller member 18 in a static status engages in a non-operated status; a gradually increasing torque peak cam surface 27b which is connected to the static engagement cam surface 27a and with which the roller member 18 is brought into contact while moving to thereby gradually increase the torque peak value; a cam top surface 27c forming the cam top portion continued to the gradually increasing torque peak cam surface 27b; a gradually decreasing torque cam surface 27d for gradually decreasing a plus torque to the roller member 18 to zero; and a minus torque cam surface 27e for imparting a minus torque to the roller member 18 having passed over the gradually decreasing torque cam surface 27d.

An insulating ratchet wrench includes a wrench body, a ratchet assembly, a main insulator and a knob. The wrench body is covered with the main insulator. The main insulator has a first insulating ring and a second insulating ring. The first insulating ring has a main annular wall and a sub annular wall. The knob has a main annular groove and a sub annular groove. Under this arrangement, the knob is assembled with the main insulator by the main annular groove and the sub annular groove sleeving onto the main annular wall and the sub annular wall respectively so as to form an overlapping structure between the ratchet assembly and the knob. When a user rotates the knob or holds the wrench body near the ratchet assembly, the main insulator avoids an electric shock in a saltatory conduction manner from a charged object via the ratchet assembly.

An adaptor tool comprises a locking pin removably engaged with a main body defining a hook portion. The main body is configured to pivot about a pivot pin. The adaptor tool further includes a first link having first and second ends, and a first contact face. The first link is configured to receive the locking pin. A second link includes first and second ends, and a second contact face. The second link is pivotally coupled to the main body via the pivot pin. At least a third link includes first and second ends, and a third contact face. The first, second, and at least third links are pivotally coupled end-to-end such that the first, second, and third contact faces define a circular opening. The circular opening is configured to receive a workpiece such that rotational force applied to the main body rotates the adaptor tool and the workpiece.

A wrench includes a handle, a first driver, and a second driver. The first driver and the second driver are integrally connected to two ends of the handle respectively. An angle between a driving axis of the first driver and a central axis of the handle is α, an angle between one opening end of the first driver and the handle is φ, an angle between a driving axis of the second driver and the central axis of the handle is β, and an angle between one opening end of the second driver and the handle is θ. The angle α and the angle β are located at two sides of the central axis of the handle respectively. The other opening end of the first driver and the other opening end of the second driver are horizontally connected to the handle respectively.

A ratchet wrench includes a wrench body, a ratchet rotatably mounted in the wrench body and defining therein a through hole for accommodating a screw nut, a magnetic member mounted in the through hole, and one or multiple limiters mounted in the through hole of the ratchet to hold the magnetic member in place. Thus, the opposing ends of the ratchet can be selectively used to accommodate a mating screw nut and the accommodated screw nut can be secured in place inside the ratchet by the magnetic attractive force of the magnetic member, avoiding screw nut displacement or falling and facilitating the use of the ratchet wrench. Further, the ratchet can be configured to have a stepped through hole for selectively accommodating different sizes of screw nuts.

The wrench adaptor of this invention provides an easy and convenient tool for connection and disconnection of the SMA connections in constrained spaces while allowing use of a standard torque wrench or just fingers. The channel design of the wrench adaptor, accommodating the cable and the protective sleeve therefor, allows access to SMA connectors without bending or disturbing semi-rigid or rigid cables. The wrench adaptor is shown in two embodiments—a single-ended and a double-ended form. The adaptor facilitates access to the hexagonal nut at the panel of an RF device which is mounted to a threaded stud and offsets the wrench application to a location away from the panel. As many of the RF cables have crimped or soldered portions adjacent or within the connector, provision is made in the adaptor by way of a hollow semicylindrical form to cradle the semi-rigid or rigid cable.

A ratchet wretch includes a first recess, a second recess and a third recess. A ratchet wheel is rotatably located in the first recess and a pawl is located in the second recess. The pawl has a curved recess defined in the rear side thereof and a protrusion extending therefrom. A first face is defined between the protrusion and the curved recess. A second face is defined in the pawl and located away from the third recess. The rotatable unit comprises a rotatable member, a first hat and a resilient member. The rotatable unit has a circular rod pivotably connected to the third recess. The circular rod has a restriction slot and three top surfaces. One of the top surfaces contacts the second face to restrict the rotatable member from disengaging from the third recess. The first hat and the resilient member are located in the restriction slot.

A milling tool holder wrench is provided. A wrench includes two knobs that protrude outward and perpendicular from a surface of the wrench at a top end of a u-shaped portion of the wrench. The knobs adapted to snuggly engage recessed fittings of a milling tool holder to lock the milling tool holder steady within a milling machine while a tool is changed from the milling tool holder.

A torque wrench includes a hollow body, a clutch mechanism, a force-applying member, and driving arms. The clutch mechanism is mounted in the hollow body. The force-applying member is pivotally mounted in the hollow body. Each of driving arms has a coupling end is detachably mounted at the second end of the force-applying member and a driving end for driving a workpiece, wherein each of the driving arms is coaxial to the force-applying member when the coupling end thereof is mounted at the second end of the force-applying member, and wherein the interchangeable driving arms are different in length from each other.

A wrench includes a body having a working end which has a first toothed portion, a first room, a second room, a third room and a first pivot cavity. The second and third rooms open through the top of the body. A driving unit is pivotably connected to the working end and has a first recess and a second recess for receiving a first pawl and a second pawl therein. The first pawl has teeth engaged with the first toothed portion, and the second pawl has teeth engaged with a second toothed portion of a first teeth disk in the first room. A second teeth disk is pivotably located in the second room and has a forth toothed portion which is engaged with a third toothed portion of the first teeth disk. A shaft is pivotably located in the third room and is connected to the second teeth disk.

A socket wrench with a positioning device contains: a body including an accommodating cavity, a first face, and a second face. A toothed holder is accommodated in the accommodating cavity and has a polygonal groove, a first circular portion, a second circular portion, and a ratchet protrusion between the first circular portion and the second circular portion. The first circular portion is inserted to the first face, the second circular portion is inserted to the second face, and the ratchet protrusion engages with a ratchet device. A positioning device includes at least one retaining element disposed on the first circular portion and horizontally moving in the polygonal groove. The first circular portion has a resilient element and a pressing loop which are fitted on the first circular, and the pressing loop has a recess defined on an inner face thereof to correspond to the at least one retaining element.

A wrench including a handle having a first yoke at a first end and a first plurality of tool heads coupled to the first yoke at a first pivot axis, at least a first tool head of the first plurality of tool heads having a drive cavity. Each tool head of the first plurality of tool heads is pivotable about the first pivot axis independently of the other tool heads of the first plurality of tool heads.

The invention relates to a guiding device for guiding an oblong intermediate element while joining at least two decorative elements by means of this intermediate element.