Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

Terry Roggensack, The Hightower Report

This report outlines the progress made by banks in implementing the Basel Committee's Principles for effective risk data aggregation and risk reporting ("the Principles" or "BCBS 239")1 based on supervisors' assessments conducted in 2019.

After preaching in a church and serving the community, team members each receive an egg as a gift from a local woman.

On 19 March, OM Australia moved into their new home, a place that will help mobilise more people and finances into missions.

As OM Austria prepares for its 50th anniversary this summer, they have been delving into old records and photos. Read about how a flower seller named Heidi was to become key to the growth of ministry in Austria...

In the 70s, OM was considered a strange movement that thought ordinary Christians could share the Gospel and train workers—a revolutionary idea in those days.

'Digicel Unplugged', the online performance series sponsored by the telecommunications firm, returns this Sunday with the Mother's Day edition featuring veteran reggae crooner Freddie McGregor, and young recording artiste Sevana.The event will be streamed live on Digicel's Instagram, Facebook and Twitter pages beginning at 2:00 pm.

A 53-year-old man has been arrested in connection with smuggling firearms into the country.

FOR decades, both Celtic and Rangers have dominated the national conversation when it comes to football in Scotland. The vast majority of issues seem to revolve around the two Glasgow clubs and, predictably, the issue of how to conclude the Premiership campaign has been boiled down to whether or not Celtic should be crowned champions if – as is looking increasingly likely – the 2019/20 campaign is unable to be played to a finish.

Dell's Latitude 7220 Rugged Extreme Tablet lives up to its name by laughing at drops, splashes, and temperatures that would blow the average slate to smithereens. It's ideal for first responders and factory floors.

The move to middle school can be a rougher adjustment for students who were high achievers at their elementary schools, finds a new study.

Seeing an opportunity to talk about Jesus’ sacrifice on the cross, the staff at SonRise Café in Tokyo sells Easter eggs before Easter.

At a recent event to build relationships, OMer Chris guides participants through the process of making juggling balls before teaching them how to juggle.

OMer Chris Griffioen was asked to perform a juggling show at an elderly care facility, and has since been invited to visit regularly.

Source: Public News Service - Economists warn that the costs of climate change in the U.S. – including from the health impacts of air pollution and natural disasters such as hurricanes and wildfires – could top $350 billion annually in the next 10 years.

The Global Trigger Tool uses a sampling methodology to identify and measure harm rates. It has been shown to effectively detect adverse events when applied in the adult environment, but it has never been evaluated in a pediatric setting.

The Global Trigger Tool can be used in the pediatric inpatient environment to measure adverse safety events. We detected a 2 to 3 times higher harm rate than previously found with different metrics in this setting. (Read the full article)

Trigger scores and early warning systems provide an objective measure of a patient’s condition, allowing earlier recognition of severe illness and adaptation of care. Such scores are established in adult and pediatric populations but remain unevaluated and rarely used in neonates.

This newly designed Neonatal Trigger Score provides an objective adjunct to multidisciplinary clinical assessment in detecting unwell neonates. It is more sensitive and specific than previously validated pediatric early warning system scores. (Read the full article)

Popular press and research show that sibling aggression is common. Too often, however, it is dismissed as benign, and other forms of child aggression, such as peer aggression, are considered more serious. Peer aggression is linked to poorer mental health.

Using a national probability sample, we show that the nature and severity of sibling aggression have negative links to children’s and adolescents’ mental health. We demonstrate that sibling and peer aggression are comparable their links to symptoms of distress. (Read the full article)

After mild traumatic brain injury, most youth recover well. A minority of patients report persistent symptoms, which relate to both injury and noninjury factors. In adult studies, validity test performance is 1 noninjury factor that relates to persistent symptoms.

This is the first pediatric study to demonstrate that validity test failure is associated with increased symptoms after mild traumatic brain injury. The findings suggest that some symptoms conceptualized as injury-related "postconcussive" problems are better explained by exaggeration or feigning. (Read the full article)

Harm occurs at a high rate in adult inpatient populations. One single-center study, applying an adult-based surveillance tool, suggests that a pediatric inpatient population also has a high rate of harm.

Harm occurred frequently in 6 freestanding children’s hospitals. Identification and understanding of the harm is the first step to making necessary improvements and to preventing future harm. (Read the full article)

Investment consultant, Andre Tuck, tackles the question of investment strategy.

For decades, special education advocates have urged the federal government to "fully fund" the Individuals with Disabilities Education Act. Here are some examples 'ripped from the headlines' of how the funding gap is affecting school districts.

This Sweepstakes is open to individuals 18 and older who are legal US residents.

Mentoring a student-teacher won't hurt a teacher's district evaluation score—in fact, it might even give it a boost, according to a working study.

Saudi Arabian stocks retreated as US Secretary of State Michael Pompeo arrived in the kingdom to meet with King Salman bin Abdulaziz over the disappearance of writer Jamal Khashoggi in Turkey.

Turkish President Recep Tayyip Erdogan rejected Riyadh’s account of the killing of dissident journalist Jamal Khashoggi at Saudi Arabia’s consulate in Istanbul, saying the murder was the result of a meticulously planned plot and calling on the Saudi king to hold all culprits to account.

For a moment, Wall Street seemed to be inching away from Saudi Arabia. Now, it’s already inching back.

Antimicrobial peptides and proteins play critical roles in the host defense against invading pathogens. We recently discovered that recombinantly expressed human and mouse serum amyloid A1 (rhSAA1 and rmSAA1) proteins have potent antifungal activities against the major human fungal pathogen Candida albicans. At high concentrations, rhSAA1 disrupts C. albicans membrane integrity and induces rapid fungal cell death. In the current study, we find that rhSAA1 promotes cell aggregation and targets the C. albicans cell wall adhesin Als3. Inactivation of ALS3 in C. albicans leads to a striking decrease in cell aggregation and cell death upon rhSAA1 treatment, suggesting that Als3 plays a critical role in SAA1 sensing. We further demonstrate that deletion of the transcriptional regulators controlling the expression of ALS3, such as AHR1, BCR1, and EFG1 in C. albicans results in similar effects to that of the als3/als3 mutant upon rhSAA1 treatment. Global gene expression profiling indicates that rhSAA1 has a discernible impact on the expression of cell wall- and metabolism-related genes, suggesting that rhSAA1 treatment could lead to a nutrient starvation effect on C. albicans cells.

The rapid evolution of resistance in the malaria parasite to every single drug developed against it calls for the urgent identification of new molecular targets. Using a stain specific for the detection of intracellular amyloid deposits in live cells we have detected the presence of abundant protein aggregates in Plasmodium falciparum blood stages and female gametes cultured in vitro, in the blood stages of mice infected by Plasmodium yoelii, and in the mosquito stages of the murine malaria species Plasmodium berghei. Aggregated proteins could not be detected in early rings, the parasite form that starts the intraerythrocytic cycle. A proteomics approach was followed to pinpoint actual aggregating polypeptides in functional P. falciparum blood stages, which resulted in the identification of 369 proteins, with roles particularly enriched in nuclear import-related processes. Five aggregation-prone short peptides selected from this protein pool exhibited different aggregation propensity according to Thioflavin-T fluorescence measurements, and were observed to form amorphous aggregates and amyloid fibrils in transmission electron microscope images. The results presented suggest that generalized protein aggregation might have a functional role in malaria parasites. Future antimalarial strategies based on the upsetting of the pathogen's proteostasis and therefore affecting multiple gene products could represent the entry to new therapeutic approaches.

Stock markets struggled on Friday as hopes of quickly finding a treatment for coronavirus were dashed, analysts said, and more crushing economic data delivered a body blow to confidence.

Extremely low or negative yields in global markets make it challenging for investors to generate meaningful returns, says Brian McMillan of Investec Structured Products.

For decades, special education advocates have urged the federal government to "fully fund" the Individuals with Disabilities Education Act. Here are some examples 'ripped from the headlines' of how the funding gap is affecting school districts.

With the coronavirus pandemic pressing tens of thousands of the nation's school districts into extended closures, education administrators across the nation are wrestling with a complex and legalistic problem: how to keep services flowing for students with disabilities.

The tiny, rugged Atom smartphone is being followed up with the Atom XL, which increases the display size to 4-inches and adds a 48MP camera.

Source: www.geekwire.com - Friday, May 08, 2020
University of Washington researchers work with the virus that causes COVID-19 in a restricted lab. (UW Medicine via YouTube) In a newly published study, a University of Washington researcher argues that the eventual death toll from COVID-19 could be more than twice as high as the figures currently being discussed. The study was written by Anirban Basu, a health economist and statistician who’s the director of UW’s Comparative Health Outcomes, Policy and Economics Institute, also known as the CHOICE Institute . In his research paper , published online Thursday by the journal Health Affairs, Basu acknowledges there’s still lots of uncertainty surrounding the fatality rate for the disease caused by the coronavirus known as SARS-CoV-2. But he says there’s evidence that the U.S. death toll could amount to 350,000 to 1.2 million. Anirban Basu is the Stergachis Family Endowed Director of the CHOICE Institute at the University of Washington’s School of Pharmacy. (UW Photo) “This is a staggering number, which can only be brought down with sound public health measures,” Basu said in an interview with MedicalResearch.com . The latest projections from UW’s Institute for Health Metrics and Evaluation estimate that the U.S. death toll due to COVID-19 will amount to nearly 135,000 by Aug. 4. IHME’s projections are closely watched (and occasionally lowballed) by the White House. “We’ll be at 100,000” or 110,000 deaths, President Donald Trump to

Facebook's policy on political ads is no different than those of campaign commercials, but the social network's size and scale makes the debate more serious.

Biometrics are generally a good alternative to passwords, but authentication via face-scanning is a terrible idea, according to security expert Max Eddy.

Source: www.youtube.com - Monday, April 27, 2020

Fin24 took to the streets of Cape Town and Johannesburg asking people to share their views on Finance Minister Pravin Gordhan's Budget Speech.

A young girl in Bangladesh finds comfort in education in the midst of tragic circumstances.

Defying the notion that business-focused smartphones need to be clunky and thick, Samsung's Galaxy XCover Pro is thin, light, and durable. Use it as a walkie-talkie, a mobile point-of-sale (POS) system, and however you get work done.

Fly your DJI drone using a first-person perspective up to a range of 2.5 miles and race with up to seven other drones using the same low-latency system.

With a perfect record at home to Belgian visiitors, Manchester United hold the upper hand after a 1-1 draw at Club Brugge, who have never won in England.