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Why legislative proposals to improve drug and device development must look beyond FDA approvals


Legislative proposals to accelerate and improve the development of innovative drugs and medical devices generally focus on reforming the clinical development and regulatory review processes that occur before a product gets to market. Many of these proposals – such as boosting federal funding for basic science, streamlining the clinical trials process, improving incentives for development in areas of unmet medical need, or creating expedited FDA review pathways for promising treatments – are worthy pursuits and justifiably part of ongoing efforts to strengthen biomedical innovation in the United States, such as the 21st Century Cures initiative in the House and a parallel effort taking shape in the Senate.

What has largely been missing from these recent policy discussions, however, is an equal and concerted focus on the role that postmarket evidence can play in creating a more robust and efficient innovation process. Data on medical product safety, efficacy, and associated patient outcomes accrued through routine medical practice and through practical research involving a broad range of medical practices could not only bolster our understanding of how well novel treatments are achieving their intended effects, but reinforce many of the premarket reforms currently under consideration. Below and in a new paper, we highlight the importance of postmarket evidence development and present a number of immediately achievable proposals that could help lay the foundation for future cures.

Why is postmarket evidence development important?

There are a number of reasons why evidence developed after a medical product’s approval should be considered an integral part of legislative efforts to improve biomedical innovation. First and foremost, learning from clinical experiences with medical products in large patient populations can allow providers to better target and treat individuals, matching the right drug or device to the right patient based on real-world evidence. Such knowledge can in turn support changes in care that lead to better outcomes and thus higher value realized by any given medical product.

Similarly, data developed on outcomes, disease progression, and associated genetic and other characteristics that suggest differences in disease course or response to treatment can form the foundation of future breakthrough medical products. As we continue to move toward an era of increasingly-targeted treatments, this important of this type of real-world data cannot be discounted.

Finally, organized efforts to improve postmarket evidence development can further establish infrastructure and robust data sources for ensuring the safety and effectiveness of FDA-approved products, protecting patient lives. This is especially important as Congress, the Administration, and others continue to seek novel policies for further expediting the pre-market regulatory review process for high-priority treatments. Without a reliable postmarket evidence development infrastructure in place, attempts to further shorten the time it takes to move a product from clinical development to FDA approval may run up against the barrier of limited capabilities to gather the postmarket data needed to refine a product’s safety and effectiveness profile. While this is particularly important for medical devices – the “life cycle” of a medical device often involves many important revisions in the device itself and in how and by whom it is used after approval – it is also important for breakthrough drugs, which may increasingly be approved based on biomarkers that predict clinical response and in particular subpopulations of patients.

What can be done now?

The last decade has seen progress in the availability of postmarket data and the production of postmarket evidence. Biomedical researchers, product developers, health care plans, and providers are doing more to collect and analyze clinical and outcomes data. Multiple independent efforts – including the U.S. Food and Drug Administration’s Sentinel Initiative for active postmarket drug safety surveillance, the Patient-Centered Outcomes Research Institute’s PCORnet for clinical effectiveness studies, the Medical Device Epidemiology Network (MDEpiNet) for developing better methods and medical device registries for medical device surveillance and a number of dedicated, product-specific outcomes registries – have demonstrated the powerful effects that rigorous, systematic postmarket data collection can have on our understanding of how medical products perform in the real-world and of the course of underlying diseases that they are designed to treat.

These and other postmarket data systems now hold the potential to contribute to data analysis and improved population-based evidence development on a wider scale. Federal support for strengthening the processes and tools through which data on important health outcomes can be leveraged to improve evidence on the safety, effectiveness, and value of care; for creating transparent and timely access to such data; and for building on current evidence development activities will help to make the use of postmarket data more robust, routine, and reliable.

Toward that end, we put forward a number of targeted proposals that current legislative efforts should consider as the 2015 policy agenda continues to take shape:

Evaluate the potential use of postmarket evidence in regulatory decision-making. The initial Cures discussion draft mandated FDA to establish a process by which pharmaceutical manufacturers could submit real-world evidence to support Agency regulatory decisions. While this is an important part of further establishing methods and mechanisms for harnessing data developed in the postmarket space, the proposed timelines (roughly 12 months to first Guidance for Industry) and wide scope of the program do not allow for a thoughtfully-, collaboratively-considered approach to utilizing real-world evidence. Future proposals should allow FDA to take a longer, multi-stakeholder approach to identify the current sources of real-world data, gaps in such collection activities, standards and methodologies for collection, and priority areas where more work is needed to understand how real-world data could be used.

Expand the Sentinel System’s data collection activities to include data on effectiveness. Established by Congress in 2007, Sentinel is a robust surveillance system geared toward monitoring the safety of drugs and biologics. In parallel to the program for evaluating the use of RWE outlined above, FDA could work with stakeholders to identify and pursue targeted extensions of the Sentinel system that begin to pilot collection of such data. Demonstration projects could enable faster and more effective RWE development to characterize treatment utilization patterns, further refine a product’s efficacy profile, or address pressing public health concerns – all by testing strategic linkages to data elements outside of Sentinel’s safety focus.

Establish an active postmarket safety surveillance system for medical devices. Congress has already acted once to establish device surveillance, mandating in 2012 that Sentinel be expanded to include safety data on medical devices. To date, however, there has been no additional support for such surveillance or even the capability of individually tracking medical devices in-use. With the recently finalized Unique Device Identifier rule going effect and the ability to perform such tracking on the horizon, the time is now to adopt recent proposals from FDA’s National Medical Device Postmarket Surveillance System Planning Board. With Congressional authorization for FDA to establish an implementation plan and adequate appropriations, the true foundation for such a system could finally be put into place.

These next steps are practical, immediately achievable, and key to fully realizing the intended effect of other policy efforts aimed at both improving the biomedical innovation process and strengthening the move to value-based health care.

Authors

      




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Bolivian re-elections: Slaves of the people or the institutions


Recently, Bolivian President Evo Morales declared himself a “slave of the people” and said he is backing the proposed constitutional reform that would enable him to seek re-election in 2019 if that’s what the citizens want. Last Saturday, September 26, the Legislative Assembly partially amended the Constitution (by a two-thirds majority), authorizing Morales to run for the presidency once again in 2019. February 21, 2016 is set as the date of the popular referendum to validate or reject the amendment.

This amendment allows presidential re-election for two consecutive terms, rather than just one re-election, as dictated by the previous constitutional provision. The change takes into account the current presidential term (2015-2020) and clarifies that Evo and his vice president are authorized to run only one more time, that is, to seek re-election only for the 2020 to 2025 period. The opposition immediately denounced the amendment as “tailoring the law to the needs of one person”.

It should be noted that Morales and García ran and won in the 2005, 2009, and 2014 elections. The current term is the second consecutive term under the new Bolivian Constitution (adopted in 2009) and the third since they were first elected, in 2005. If he wins the elections scheduled for 2019, Evo would become one of the leaders to hold power the longest in Bolivia and throughout Latin America.

Re-election fever

This constitutional amendment, recently adopted in Bolivia, is not an isolated event. Rather, it fits within a regional trend toward re-election that has been gaining ground in Latin America over the past 20 years.

While the region ushered in democracy in the late 1970s and many clearly opposing re-election, this situation changed dramatically a few years later. The first wave of reforms favorable to immediate or consecutive re-election came in the first half of the 1990s with the impetus of Alberto Fujimori in Peru (1993), Carlos Menem in Argentina (1994), and Fernando Henrique Cardoso in Brazil (1997). From then on, several more presidents introduced reforms during their administrations to keep themselves in power. A second wave of reforms, led by Hugo Chávez, took place in the middle of the last decade, with a view to moving from immediate re-election to indefinite re-election. Chávez secured this objective via referendum in 2009.

Chávez’s example was reproduced by Daniel Ortega in 2014 in Nicaragua (the second country to allow indefinite re-election). Currently one more president, Rafael Correa (Ecuador), is promoting a reform along similar lines.

Recent reforms and trends

The years 2014 and 2015 have been full of news a about re-election. In the last 20 years the Dominican Republic has led in the number of re-election related reforms, with four from 1994 to 2015. The most recent, in July 2015, has re-established immediate re-election, enabling President Danilo Medina to run once again in May 2016 elections to aspire to a second consecutive term.

Two more countries have moved in what some might call extreme directions in 2014 and 2015. Nicaragua eliminated any impediment to re-election from the constitution in January of 2014, while Colombia moved in the opposite direction when they approved a reform prohibiting presidential re-election, in June 2015, a decade after re-election was first adopted.

On April 22, 2015, the Honduran Supreme Court declared the articles of the constitution that prohibited presidential re-election inapplicable. These articles also punished public officials and any other citizen who proposed or supported amending them, as these articles were considered not subject to reform. In 2009 the effort to call a National Constitutional Assembly after a non-binding consultation to amend the constitution and do away with this provision, led to the coup d’état that removed former President Zelaya from office.

In Brazil, the Chamber of Deputies cast an initial vote in 2015 in favor of eliminating re-elections, which is now being examined in the Senate. Most analysts consider it likely that the senate will adopt a similar position as the lower house, i.e. in favor of doing away with re-election.

Finally, one should note the cases of Ecuador and Bolivia, countries in which efforts are under way to amend the constitutions in relation to elections, in the terms analyzed above.

As a result of the reforms of the last few years, at this time 14 of the 18 countries in the region allow re-election, albeit with different specific rules. Venezuela (since 2009) and Nicaragua (since 2014) are the only countries so far that allow indefinite re-election. In five countries – Argentine, Bolivia, Brazil, Ecuador, and the Dominican Republic – consecutive re-election is allowed, but not indefinitely (only one re-election is permitted). Nonetheless, presidents who re-founded the institutional order through constitutional assemblies have been able to benefit from a third term, leaving out the first term on the argument that it pre-dated the constitutional reforms (Bolivia and Ecuador). To these five countries we should added the above-mentioned case of Honduras.

In six other countries one can return to the presidency after an interval of one or two presidential terms. These are Chile, Costa Rica, El Salvador, Panama, Peru, and Uruguay. As we have observed, only four countries have an absolute prohibition on any type of re-election, namely Mexico, Guatemala, Paraguay, and, since last July, Colombia.

My opinion

This re-election fever is bad news for a region like ours given the institutional weaknesses, the crisis of the political parties, the growing personalization of politics, and, in several countries, hyper-presidentialism.

Something is very wrong when a president of a democracy considers himself or herself as indispensable as to change the constitution in order to stay in power. As Pope Francis noted recently; “a good leader is one who is capable of bringing up other leaders. If a leader wants to lead alone, he is a tyrant. True leadership is fruitful.”

“The leaders of today will not be here tomorrow. If they do not plant the seed of leadership in others, they are worthless. They are dictators,” he concluded.

I agree with Pope Francis. The health of a democracy depends essentially on its ability to limit the power of those in government so they cannot reshape the law to fit their personal ambitions. In other words, democracy in Latin America does not need leaders who are slaves of the people, but who are slaves to the law and the institutions.

This piece was originally published by International IDEA.

Authors

Publication: International IDEA
Image Source: © David Mercado / Reuters
      
 
 




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The believer: How Abu Bakr al-Baghdadi became leader of the Islamic State

Ibrahim Awwad Ibrahim al-Badri was born in 1971 in Samarra, an ancient Iraqi city on the eastern edge of the Sunni Triangle north of Baghdad. The son of a pious man who taught Quranic recitation in a local mosque, Ibrahim himself was withdrawn, taciturn, and, when he spoke, barely audible. Neighbors who knew him as…

       




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Drones and Aerial Surveillance: Considerations for Legislators


     
 
 




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The Islamic Republic of Iran four decades on: The 2017/18 protests amid a triple crisis

Throughout its tumultuous four decades of rule, the Islamic Republic has shown remarkable longevity, despite regular predictions of its im- pending demise. However, the fact that it has largely failed to deliver on the promises of the 1979 revolution, above all democracy and social justice, continues to haunt its present and future. Iran’s post-revolutionary history…

       




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The legal foundations of the Islamic State


Media coverage of the Islamic State frequently refers to the group’s violent and seemingly archaic justice system without considering the institutional structures that enable this violence, or the broader function that it serves in the group’s ambitious state-building project. Legal institutions make it easier for the group to capture and retain territory by legitimizing its claim to sovereignty, justifying the expropriation of the property and land of enemies, and building goodwill with civilians by ensuring accountability.

The Islamic State’s legal system purports to strictly apply the divinely revealed body of Islamic law known as Sharia, which it regards as the only legitimate basis for governance. Although its legal system is frequently characterized as medieval, it has instrumentally supplemented the original text of the Quran with the modern rules and regulations that are needed to govern a 21st century state and punish modern day offenses—for example, traffic violations. It has the same three features that are present in any modern legal system: police, courts, and prisons.

In a region that has long been plagued by corruption, the Islamic State has attempted to ingratiate itself with civilians by claiming that its legal system is comparatively more legitimate and effective than the available alternatives. However, two emerging vulnerabilities—the system’s susceptibility to corruption and propensity for extra-legal violence—are increasingly undermining the Islamic State’s ability to obtain the trust and cooperation of civilians. Counterinsurgency efforts should be designed to undermine the legitimacy of its institutions. Long-term solutions in the region must involve a fundamental reorganization of political and legal institutions in ways that promote legitimacy and rule of law.

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Authors

  • Mara Revkin
Image Source: © Stringer . / Reuters
         




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What are the legal foundations of the Islamic State?


Media coverage of the Islamic State has focused on the group’s grotesque use of violence and archaic governance style. Less attention has been paid, however, to the institutions that make those practices possible—institutions that lend the group legitimacy, at least in the eyes of supporters, as a sovereign state. In her new Brookings Analysis Paper, “The legal foundations of the Islamic State,” Mara Revkin argues that legal institutions play a critical role in the Islamic State’s state-building project. Those structures help the group take and keep territory, as well as provide a measure of accountability to the people living under its rule.

Lesser evil?

Revkin writes that “the Islamic State has attempted to ingratiate itself with civilians by claiming that its legal system is comparatively more legitimate and effective than the available alternatives.” The Syrian and Iraqi governments, Revkin explains, are often perceived as being highly corrupt and ineffective. The Islamic State is able to gain civilians’ favor by arguing that its political and legal institutions are more legitimate than those of the Syrian and Iraqi governments or rival armed groups. She adds: “some Syrians and Iraqis seem to prefer the legal system of the Islamic State to the available alternatives not because they agree with its ideology, but simply because they regard it as the lesser evil.” 

The Syrian and Iraqi governments...are often perceived as being highly corrupt and ineffective.

Revkin writes that for the Islamic State, shariah law is “the only legitimate basis for governance.” In cases where shariah fails to address modern-day problems, she explains, religiously legitimate authorities appointed by the Islamic State—such as military commanders, police officers, and the caliph himself—can issue legal decisions as long as they do not conflict with the divine rules of shariah or harm the welfare of the greater Muslim community. Alongside this is a system of rules and regulations to “govern civilians, discipline its own officials and combatants, and control territory” in areas of rights and duties, behavior, property, trade, and warfare. 

Making the state possible

Legal institutions help the Islamic State advance three main state-building objectives, in Revkin’s view: 

  1. First, they support the Islamic State’s territorial expansion by “legitimizing [its] claims to sovereignty, justifying the expropriation of the property and land of enemies, and building goodwill with civilians.” 
  2. Legal institutions also allow the Islamic State to enforce compliance and accountability of its own members and maintain internal control and discipline. Revkin describes various types of punishments the Islamic State uses to discipline its own members—these punishments are important, she writes, because “no government can establish itself as legitimate and sovereign without policing the behavior of the people who are responsible for implementing its policies.”
  3. Finally, Revkin explores the legal institutions surrounding the Islamic State’s tax policies, which are “critical to financing the Islamic State’s governance and military operations.” Courts and judges, she explains, are crucial to “administering and legitimizing” taxation and justifying “economic activities that might otherwise resemble theft.” 

Weaknesses in the system

Although the Islamic State claims to have legitimate governing authority, based on a defined legal system, that system faces vulnerabilities. Revkin writes, for instance, that reports of corruption and extra-legal violence are “threatening the organization’s long-term sustainability and undermining its ability to win the trust and cooperation of civilians.”

Amid recent signs that the group is losing strength, Revkin argues that it’s struggling to maintain its own moral standards. To further weaken the Islamic State, she recommends working to undermine those institutions. The trouble is, as Revkin points out: “the Islamic State came to power largely by exploiting the weakness and illegitimacy of existing institutions” in Iraq and Syria. Thus, a sustainable plan for ultimately destroying the organization must also involve strengthening political and legal institutions in those countries. 

Authors

  • Dana Hadra
         




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What are the legal foundations of the Islamic State?

Media coverage of the Islamic State has focused on the group’s grotesque use of violence and archaic governance style. Less attention has been paid, however, to the institutions that make those practices possible—institutions that lend the group legitimacy, at least in the eyes of supporters, as a sovereign state. 

       
 
 




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The polarizing effect of Islamic State aggression on the global jihadi movement

      
 
 




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Profiling the Islamic State


Brookings Doha Center Analysis Paper, December 1, 2014

Intense turmoil in Syria and Iraq has created socio-political vacuums in which jihadi groups have been able to thrive. The Islamic State in Iraq and al-Sham (ISIS) had proven to be the strongest and most dynamic of these groups, seizing large swathes of territory in Syria and Iraq. Shortly after routing Iraqi forces and conquering Mosul in June 2014, ISIS boldly announced the establishment of a caliphate and renamed itself the Islamic State (IS). How did IS become such a powerful force? What are its goals and characteristics? What are the best options for containing and defeating the group?

In a new Brookings Doha Center Analysis Paper, Charles Lister traces IS’s roots from Jordan to Afghanistan, and finally to Iraq and Syria. He describes its evolution from a small terrorist group into a bureaucratic organization that currently controls thousands of square miles and is attempting to govern millions of people. Lister assesses the group’s capabilities, explains its various tactics, and identifies its likely trajectory.

According to Lister, the key to undermining IS’s long-term sustainability is to address the socio-political failures of Syria and Iraq. Accordingly, he warns that effectively countering IS will be a long process that must be led by local actors. Specifically, Lister argues that local actors, regional states, and the international community should work to counter IS’s financial strength, neutralize its military mobility, target its leadership, and restrict its use of social media for recruitment and information operations.

Image Source: © Stringer . / Reuters
     
 
 




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Collusion to Crackdown: Islamist-Military Relations in Egypt


Nearly two years after ousting President Muhammad Morsi, Egypt’s military continues to crack down on the Muslim Brotherhood. Much like during Egypt’s 1952-54 political transition, the recent interactions between the powerful armed state bureaucracy and the influential religious organization have had a major impact on the country’s political trajectory. In both instances, the military and Muslim Brotherhood initially cooperated before ultimately clashing violently. How has each entity determined what approach to take toward the other? What does a continued imbalance in civil-military relations mean for Egypt’s future?

In a new Brookings Doha Center Analysis Paper, Omar Ashour examines the legacies and patterns of cooperation and conflict between the leaderships of Egypt’s military and the Muslim Brotherhood. Relying on extensive field research, he analyzes how each entity has made its critical decisions regarding the other by applying various decision-making models. Ashour considers the impact of cost-benefit analysis, organizational dynamics, factional disputes, and psychological factors to gain a deep understanding of the leaders’ motives.

Read "Collusion to Crackdown: Islamist-Military Relations in Egypt"

Ashour concludes that Egypt's prospects for social stability and economic recovery will remain bleak if the relationship between the military and the Muslim Brotherhood is not redefined within institutional, democratic rules of political competition. He argues that Egypt’s military should embrace a balanced civil-military relationship to realize broad, long-term benefits and avoid otherwise inevitable and costly clashes with segments of Egyptian society. As for the Muslim Brotherhood, Ashour recommends that it reevaluate its recent decisions and work to develop a sustained, solid, and cross-ideological civilian front that can pressure the military to leave politics and allow for democratization.

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Publication: The Brookings Doha Center
Image Source: © Stringer . / Reuters
     
 
 




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Jihadi rivalry: The Islamic State challenges al-Qaida


International jihad has undergone a wholesale internal revolution in recent years. The dramatic emergence of the Islamic State (IS) and its proclamation of a Caliphate means that the world no longer faces one Sunni jihadi threat, but two, as IS and al-Qaida compete on the global stage. What is the relationship between the groups and how do their models differ? Is IS’s rapid organizational expansion sustainable? Can al-Qaida adapt and respond?

Read "Jihadi Rivalry: The Islamic State Challenges al-Qaida"

In a new Brookings Doha Center Analysis Paper, Charles Lister explores al-Qaida and IS’s respective evolutions and strategies. He argues that al-Qaida and its affiliates are now playing a long game by seeking to build alliances and develop deep roots within unstable and repressed societies. IS, on the other hand, looks to destabilize local dynamics so it can quickly seize control over territory.

Lister finds that the competition between IS and al-Qaida for jihadi supremacy will continue, and will likely include more terrorist attacks on the West. Accordingly, he calls for the continued targeting of al-Qaida leaders, the disruption of jihadi financial activities, and greater domestic intelligence and counter-radicalization efforts. Lister concludes, however, that state instability across the Muslim world must be addressed or jihadis will continue to thrive.

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Authors

  • Charles Lister
Publication: The Brookings Doha Center
Image Source: © Hosam Katan / Reuters
      
 
 




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Limits on Nevada’s legislature keep it from serving the state

In the last 30 years, Nevada has evolved from a sparsely and homogenously populated rural outpost to one of the most urban and diverse states in the country. Nevada’s population is now majority-minority. The Las Vegas-Henderson-Paradise Metropolitan statistical area with over 2.2 million residents is the 28th largest in the country and is home to…

       




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Islamic exceptionalism: How the struggle over Islam is reshaping the world


Event Information

June 9, 2016
5:30 PM - 8:00 PM EDT

Falk Auditorium
Brookings Institution
1775 Massachusetts Avenue NW
Washington, DC 20036

With the rise of ISIS and a growing terrorist threat in the West, unprecedented attention has focused on Islam, which despite being the world’s fastest growing religion, is also one of the most misunderstood. In his new book “Islamic Exceptionalism: How the Struggle over Islam is Reshaping the World” (St. Martin’s Press, 2016), Senior Fellow Shadi Hamid offers a novel and provocative argument on how Islam is, in fact, “exceptional” in how it relates to politics, with profound implications for how we understand the future of the Middle East. Hamid argues for a new understanding of how Islam and Islamism shape politics by examining different modes of reckoning with the problem of religion and state, including the terrifying—and alarmingly successful—example of ISIS.

On June 9, Shadi Hamid and Isaiah Berlin Senior Fellow in Culture and Policy Leon Wieseltier discussed the unresolved questions of religion’s role in public life and whether Islam can—or should—be reformed or secularized.

Join the conversation on Twitter using #IslamicExceptionalism

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How the Islamic State could win

Let’s think the unthinkable: Could the Islamic State win? I say “unthinkable” because, discouraged as everyone has become, most commentary stops short of imagining what an Islamic State victory in the Middle East would look like. The common conviction is that the group is so evil it simply must be defeated — it will just…

      
 
 




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Islamic State and weapons of mass destruction: A future nightmare?

      
 
 




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Islamic Comrades No More

The coup last July in Egypt opened a new divide in the Middle East, alienating the Gulf monarchies from the Muslim Brotherhood. Vali Nasr looks at why this is a momentous change in the region’s strategic landscape that promises to influence governments and regional alliances for years to come.

      
 
 




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Five books you should read to better understand Islam


After a recent talk about my ISIS book, one of the audience members asked, “What can I read to help me not hate Islam?” I don’t think it’s a scholar’s job to persuade others to love or hate any culture. But the question was sincere, so I suggested some books that have helped me better understand Islam. I also put the question to Twitter. Below is some of what I and others came up with.

Two cautions before we dive in: First, the list is obviously not exhaustive and I’ve left out overly apologetic books—in my experience, they only increase the skeptical reader’s suspicion that she’s being suckered. Second, people on Twitter gave me great suggestions but I’ve only included those I’ve read and can vouch for:

Muhammad and the Quran: Two of the best books you’ll ever read about Muhammad and the Quran are also the shortest: The Koran: A Very Short Introduction and Muhammad, both by Michael Cook. He writes with great wit and deep scholarship.

Other scriptures: Most non-Muslims are unaware that Islamic scripture is more than the Quran. It includes a vast collection of words and deeds attributed to Muhammad by later authors. These scriptures are sort of like the Gospels, and Muslim scholars fight over their authenticity like Christian scholars debate about the accuracy of Matthew, Mark, Luke, and John. These extra Islamic scriptures contain most of the teachings that make modern people (Muslims included) uncomfortable about Islam. One of the world’s experts on these scriptures, Jonathan Brown, has written a terrific book about them, Misquoting Muhammad.

Rumi: The medieval mystic’s poems about life and death are beautiful and moving, no matter your belief system. I loved his poems so much as an undergrad that I went on to study Middle Eastern languages just so I could read his work in the original. I’m glad I first viewed Islam through the eyes of Rumi and not a group like ISIS. Neither is solely representative of Islam but both draw heavily on its scriptures and reach such different conclusions.

The Bible: Many people recommended reading the Bible to decrease hate of Islam. The nerd in me leapt to the least obvious conclusion, “Ah, good idea! Reading some of the rough stuff in the Hebrew Bible is a good way to put a kindred ancient religion like Islam in perspective.” But they meant something a little less complicated:

It’s a worthy perspective today no matter your faith.

Authors

Image Source: © David Gray / Reuters
     
 
 




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Experts Weigh In: What is the future of al-Qaida and the Islamic State?


Will McCants: As we wind down another year in the so-called Long War and begin another, it’s a good time to reflect on where we are in the fight against al-Qaida and its bête noire, the Islamic State. Both organizations have benefited from the chaos unleashed by the Arab Spring uprisings but they have taken different paths. Will those paths converge again or will the two organizations continue to remain at odds? Who has the best strategy at the moment? And what political changes might happen in the coming year that will reconfigure their rivalry for leadership of the global jihad?

To answer these questions, I’ve asked some of the leading experts on the two organizations to weigh in over. The first is Barak Mendelsohn, an associate professor of political science at Haverford College and a senior fellow at the Foreign Policy Research Institute (FPRI). He is author of the brand new The al-Qaeda Franchise: The Expansion of al-Qaeda and Its Consequences.


Barak Mendelsohn: Al-Qaida attacked the U.S. homeland on 9/11, unprepared for what would follow. There was a strong disconnect between al-Qaida’s meager capabilities and its strategic objectives of crippling the United States and of bringing about change in the Middle East. To bridge that gap, Osama bin Laden conveniently and unrealistically assumed that the attack on the United States would lead the Muslim masses and all other armed Islamist forces to join his cause. The collapse of the Taliban regime and the decimation of al-Qaida’s ranks quickly proved him wrong.

Yet over fourteen years later al-Qaida is still around. Despite its unrealistic political vision and considerable setbacks—above all the rise of the Islamic State that upstaged al-Qaida and threatened its survival—it has branches in North Africa, the Arabian Peninsula, the Levant, Central Asia, and the Horn of Africa.

Down, but not out

Two factors explain al-Qaida’s resilience: changes in the environment due to the Arab revolutions and the group’s ability to take advantage of new opportunities by learning from past mistakes. The Arab awakening initially undercut al-Qaida’s original claims that change in Muslim countries cannot come peacefully or without first weakening the United States. Yet, the violence of regimes against their people in Syria, Libya, and elsewhere created new opportunities for al-Qaida to demonstrate its relevance. Furthermore, involved citizens determined to shape their own future presented al-Qaida with a new opportunity to recruit. 

But favorable conditions would be insufficient to explain al-Qaida’s resilience without changes in the way al-Qaida operates. Learning from its bitter experience in Iraq, al-Qaida opted to act with some moderation. It embedded itself among rebel movements in Syria and Yemen, thus showing it could be a constructive actor, attentive to the needs of the people and willing to cooperate with a wide array of groups. As part of a broader movement, al-Qaida’s affiliates in these countries also gained a measure of protection from external enemies reluctant to alienate the group’s new allies. 

[E]ven after showing some moderation, al-Qaida’s project is still too extreme for the overwhelming majority of Muslims.

At present, the greatest threat to al-Qaida is not the United States or the Arab regimes; it’s the group’s former affiliate in Iraq, the Islamic State. ISIS is pressuring al-Qaida’s affiliates to defect—while it has failed so far to shift their allegiance, it has deepened cracks within the branches and persuaded small groups of al-Qaida members to change sides. Even if al-Qaida manages to survive the Islamic State’s challenge, in the long term it still faces a fundamental problem that is unlikely to change: even after showing some moderation, al-Qaida’s project is still too extreme for the overwhelming majority of Muslims.

Up, but not forever

With the United States seeking retrenchment and Middle Eastern regimes weakening, the Islamic State came to prominence under more convenient conditions and pursued a different strategy. Instead of wasting its energy on fighting the United States first, ISIS opted to establish a caliphate on the ruins of disintegrating Middle Eastern states. It has thrived on the chaos of the Arab rebellions. But in contrast to al-Qaida, it went beyond offering protection to oppressed Sunni Muslims by promoting a positive message of hope and pride. It does not merely empower Muslims to fend off attacks on their lives, property, and honor; the Islamic State offers its enthusiastic followers an historic chance to build a utopian order and restore the early Islamic empire or caliphate.

ISIS opted to establish a caliphate on the ruins of disintegrating Middle Eastern states. It has thrived on the chaos of the Arab rebellions.

The Islamic State’s leaders gambled that their impressive warfighting skills, the weakness of their opponents, and the reluctance of the United States to fight another war in the Middle East would allow the group to conquer and then govern territory. The gamble paid off. Not only did ISIS succeed in controlling vast territory, including the cities of Raqqa and Mosul; the slow response to its rise allowed the Islamic State’s propaganda machine to construct a narrative of invincibility and inevitability, which has, in turn, increased its appeal to new recruits and facilitated further expansion.

And yet, the Islamic State’s prospects of success are low. Its miscalculations are threatening to undo much of its success. It prematurely and unnecessarily provoked an American intervention that, through a combination of bombings from the air and skilled Kurdish proxies on the ground, is limiting the Islamic State’s ability to expand and even reversing some of the group’s gains. 

ISIS could settle for consolidating its caliphate in the territories it currently controls, but its hubris and messianic zeal do not allow for such limited goals. It is committed to pursuing military expansion alongside its state-building project. This rigid commitment to two incompatible objectives is perhaps the Islamic State’s biggest weakness. 

[T]he slow response to its rise allowed the Islamic State’s propaganda machine to construct a narrative of invincibility and inevitability.

Rather than pursue an economic plan that would guarantee the caliphate’s survival, the Islamic State has linked its economic viability to its military expansion. At present, ISIS relies on taxing its population and oil sales to support its flailing economy. But these financial resources cannot sustain a state, particularly one bent on simultaneously fighting multiple enemies on numerous fronts. Ironically, rather than taming its aspirations, the Islamic State sees conquest as the way to promote its state-building goals. Its plan for growing the economy is based on the extraction of resources through military expansion. While this plan worked well at first—when the Islamic State faced weak enemies—it is not a viable solution any longer, as the self-declared caliphate can no longer expand fast enough to meet its needs. Consequently, this strategy is undermining ISIS rather than strengthening it. 

Unfortunately, even if the Islamic State is bound to fail over the long run, it has had enough time to wreak havoc on other states in the neighborhood. And while its ability to govern is likely to continue diminishing, the terror attacks in Paris, Beirut, and Sinai suggest that the Islamic State will remain capable of causing much pain for a long time.

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Experts weigh in (part 2): What is the future of al-Qaida and the Islamic State?


Will McCants: As we begin another year in the so-called Long War, it’s a good time to reflect on where we are in the fight against al-Qaida and its bête noire, the Islamic State. Both organizations have benefited from the chaos unleashed by the Arab Spring uprisings but they have taken different paths. Will those paths converge again or will the two organizations continue to remain at odds? Who has the best strategy at the moment? And what political changes might happen in the coming year that will reconfigure their rivalry for leadership of the global jihad?

To answer these questions, I’ve asked some of the leading experts on the two organizations to weigh in. First was Barak Mendelsohn, who contrasts al-Qaida’s resilience and emphasis on Sunni oppression with the Islamic State’s focus on building a utopian order and restoring the caliphate.

Next is Clint Watts, a Fox fellow at the Foreign Policy Research Institute. He offers ways to avoid the flawed assumptions that have led to mistaken counterterrorism forecasts in recent years. 


Clint Watts: Two years ago today, counterterrorism forecasts focused on a “resurgent” al-Qaida. Debates over whether al-Qaida was again winning the war on terror ensued just a week before the Islamic State invaded Mosul. While Washington’s al-Qaida debates steamed away in 2013, Ayman al-Zawahiri’s al-Qaida suffered unprecedented internal setbacks from a disobedient, rogue affiliate formerly known as al-Qaida in Iraq (AQI). With terror predictions two years ago so far off the mark, should we even attempt to anticipate what the next two years of al-Qaida and ISIS will bring?

Rather than prognosticate about how more than a dozen extremist groups operating on four continents might commit violence in the future, analysts might instead examine flawed assumptions that resulted in the strategic surprise known as the Islamic State. Here are insights from last decade’s jihadi shifts we should consider when making forecasts on al-Qaida and the Islamic State’s future in the coming decade. 

Loyalty is fleeting, self-interest is forever. Analysts that missed the Islamic State’s rise assumed that those who pledged allegiance to al-Qaida would remain loyal indefinitely. But loyalties change despite the oaths that bind them. Abu Bakr al-Baghdadi and the Islamic State’s leaders used technicalities to slip their commitments to al-Qaida. Boko Haram has rapidly gone from al-Qaida wannabe to Islamic State devotee. 

In short, jihadi pledges of loyalty should not be seen as binding or enduring, but instead temporary. When a group’s fortunes wane or leaders change, allegiance will rapidly shift to whatever strain of jihad proves most advantageous to the group or its leader. Prestige, money, manpower—these drive pledges of allegiance, not ideology. 

Al-Qaida and the Islamic State do not think solely about destroying the United States and its Western allies. Although global jihadi groups always call for attacks on the West, they don’t always deliver. Either they can’t or they have other priorities, like attacking closer to home. So jihadi propaganda alone does not tell us much about how the group is going to behave in the future. 

Zawahiri, for example, has publicly called on al-Qaida’s affiliates to carry out attacks on the West. But privately, he has instructed his affiliate in Syria to hold off. And for most of its history, the Islamic State focused on attacking the near enemy in the Middle East rather than the far enemy overseas, despite repeatedly vowing to hit the United States. Both groups will take advantage of any easy opportunity to strike the United States. However, continuing to frame future forecasts through an America-centric lens will yield analysis that’s off the mark and of questionable utility.

[J]ihadi propaganda alone does not tell us much about how the group is going to behave in the future.

Al-Qaida and the Islamic State don’t control all of the actions of their affiliates. News headlines lead casual readers to believe al-Qaida and the Islamic State command and control vast networks operating under a unified strategic plan. But a year ago, the Charlie Hebdo attack in Paris caught al-Qaida in the Arabian Peninsula (AQAP) completely by surprise—despite one of the attackers attributing the assault to the group. Al-Qaeda in the Islamic Maghreb's (AQIM) recent spate of attacks in Mali and Burkina Faso were likely conducted independently of al-Qaida’s central leadership. While the Islamic State has clearly mobilized its network and inspired others to execute a broad range of international attacks, the group’s central leadership in Iraq and Syria closely manages only a small subset of these plots. 

At no time since the birth of al-Qaida have jihadi affiliates and networks operated with such independence. Since Osama bin Laden’s death, al-Qaida affiliates in Yemen, the Sahel, Somalia, and Syria all aggressively sought to form states—a strategy bin Laden advised against. Target selections and the rapid pace of plots by militants in both networks suggest local dynamics rather than a cohesive, global grand strategy drive today’s jihad. Accurately anticipating the competition and cooperation of such a wide array of terrorist affiliates with overlapping allegiances to both groups will require examination by teams of analysts with a range of expertise rather than single pundits. 

At no time since the birth of al-Qaida have jihadi affiliates and networks operated with such independence.

Both groups and their affiliates will be increasingly enticed to align with state sponsors and other non-jihadi, non-state actors. The more money al-Qaida and the Islamic State have, the more leverage they have over their affiliates. But when the money dries up—as it did in al-Qaida’s case and will in the Islamic State’s—the affiliates will look elsewhere to sustain themselves. Distant affiliates will seek new suitors or create new enterprises. 

Inevitably, some of the affiliates will look to states that are willing to fund them in proxy wars against their mutual adversaries. Iran, despite fighting the Islamic State in Syria, might be enticed to support Islamic State terrorism inside Saudi Arabia’s borders. Saudi Arabia could easily use AQAP as an ally against the Iranian backed Houthi in Yemen. African nations may find it easier to pay off jihadi groups threatening their countries than face persistent destabilizing attacks in their cities. When money becomes scarce, the affiliates of al-Qaida and the Islamic State will have fewer qualms about taking money from their ideological enemies if they share common short-term interests. 

If you want to predict the future direction of the Islamic State and al-Qaida, avoid the flawed assumptions noted above. Instead, I offer these three notes: 

  1. First, look to regional terrorism forecasts illuminating local nuances routinely overlooked in big global assessments of al-Qaida and the Islamic State. Depending on the region, either the Islamic State or al-Qaida may reign supreme and their ascendance will be driven more by local than global forces. 
  2. Second, watch the migration of surviving foreign fighters from the Islamic State’s decline in Iraq and Syria. Their refuge will be our future trouble spot. 
  3. Third, don’t try to anticipate too far into the future. Since bin Laden’s death, the terrorist landscape has become more diffuse, a half dozen affiliates have risen and fallen, and the Arab Spring went from great hope for democracies to protracted quagmires across the Middle East. 

Today’s terrorism picture remains complex, volatile, and muddled. There’s no reason to believe tomorrow’s will be anything different.

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Experts Weigh In (part 3): What is the future of al-Qaida and the Islamic State?


Will McCants: As we continue onwards in the so-called Long War, it’s a good time to reflect on where we are in the fight against al-Qaida and its bête noire, the Islamic State. Both organizations have benefited from the chaos unleashed by the Arab Spring uprisings but they have taken different paths. Will those paths converge again or will the two organizations continue to remain at odds? Who has the best strategy at the moment? And what political changes might happen in the coming year that will reconfigure their rivalry for leadership of the global jihad?

To answer these questions, I’ve asked some of the leading experts on the two organizations to weigh in. First was Barak Mendelsohn, who analyzed the factors that explain the resilience and weaknesses of both groups. Then Clint Watts offered ways to avoid the flawed assumptions that have led to mistaken counterterrorism forecasts in recent years. 

Next up is Charles Lister, a resident fellow at the Middle East Institute, to examine the respective courses each group has charted to date and whether that's likely to change. 


Charles Lister: The world of international jihad has had a turbulent few years, and only now is the dust beginning to settle. The emergence of the Islamic State as an independent transnational jihadi rival to al-Qaida sparked a competitive dynamic. That has heightened the threat of attacks in the West and intensified the need for both movements to demonstrate their value on local battlefields. Having spent trillions of dollars pushing back al-Qaida in Afghanistan and Pakistan and al-Qaida in Iraq, the jihadi threat we face today far eclipses that seen in 2000 and 2001.

As has been the case for some time, al-Qaida is no longer a grand transnational movement, but rather a loose network of semi-independent armed groups dispersed around the world. Although al-Qaida’s central leadership appears to be increasingly cut off from the world, frequently taking many weeks to respond publicly to significant events, its word remains strong within its affiliates. For example, a secret letter from al-Qaida leader Ayman al-Zawahiri to his Syrian affiliate the Nusra Front in early 2015 promptly caused the group to cease plotting attacks abroad.

Seeking rapid and visible results, ISIS worries little about taking the time to win popular acceptance and instead controls territory through force.

While the eruption of the Arab Spring in 2010 challenged al-Qaida’s insistence that only violent jihad can secure political change, the subsequent repression and resulting instability provided an opportunity. What followed was a period of extraordinary strategic review. Beginning with Ansar al-Sharia in Yemen (in 2010 and 2011) and then with al-Qaida in the Islamic Maghreb (AQIM), Ansar al-Din, and the Movement for Unity and Jihad in West Africa (MUJAO) in Mali (2012), al-Qaida began developing a new strategy focused on slowly nurturing unstable and vulnerable societies into hosts for an al-Qaida Islamic state. Although a premature imposition of harsh Shariah norms caused projects in Yemen and Mali to fail, al-Qaida’s activities in Syria and Yemen today look to have perfected the new “long game” approach.

In Syria and Yemen, al-Qaida has taken advantage of weak states suffering from acute socio-political instability in order to embed itself within popular revolutionary movements. Through a consciously managed process of “controlled pragmatism,” al-Qaida has successfully integrated its fighters into broader dynamics that, with additional manipulation, look all but intractable. Through a temporary renunciation of Islamic hudud (fixed punishments in the Quran and Hadith) and an overt insistence on multilateral populist action, al-Qaida has begun socializing entire communities into accepting its role within their revolutionary societies. With durable roots in these operational zones—“safe bases,” as Zawahiri calls them—al-Qaida hopes one day to proclaim durable Islamic emirates as individual components of an eventual caliphate.

Breadth versus depth

The Islamic State (or ISIS), on the other hand, has emerged as al-Qaida’s obstreperous and brutally rebellious younger sibling. Seeking rapid and visible results, ISIS worries little about taking the time to win popular acceptance and instead controls territory through force and psychological intimidation. As a militarily capable and administratively accomplished organization, ISIS has acquired a strong stranglehold over parts of Iraq and Syria—like Raqqa, Deir el-Zour, and Mosul—but its roots are shallow at best elsewhere in both countries. With effective and representative local partners, the U.S.-led coalition can and will eventually take back much of ISIS’s territory, but evidence thus far suggests progress will be slow.

Meanwhile, ISIS has developed invaluable strategic depth elsewhere in the world, through its acquisition of affiliates—or additional “states” for its Caliphate—in Yemen, Libya, Algeria, Egypt, Afghanistan, Pakistan, Nigeria, and Russia. Although it will struggle to expand much beyond its current geographical reach, the growing importance of ISIS in Libya, Egypt, and Afghanistan-Pakistan in particular will allow the movement to survive pressures it faces in Syria and Iraq. 

As that pressure heightens, ISIS will seek to delegate some level of power to its international affiliates, while actively encouraging retaliatory attacks—both centrally directed and more broadly inspired—against high-profile Western targets. Instability breeds opportunity for groups like ISIS, so we should also expect it to exploit the fact that refugee flows from Syria towards Europe in 2016 look set to dramatically eclipse those seen in 2015.

Instability breeds opportunity for groups like ISIS.

Charting a new course?

That the world now faces threats from two major transnational jihadist movements employing discernibly different strategies makes today’s counterterrorism challenge much more difficult. The dramatic expansion of ISIS and its captivation of the world’s media attention has encouraged a U.S.-led obsession with an organization that has minimal roots into conflict-ridden societies. Meanwhile the West has become distracted from its long-time enemy al-Qaida, which has now grown deep roots in places like Syria and Yemen. Al-Qaida has not disappeared, and neither has it been defeated. We continue this policy imbalance at our peril.

In recent discussions with Islamist sources in Syria, I’ve heard that al-Qaida may be further adapting its long-game strategy. The Nusra Front has been engaged in six weeks of on/off secret talks with at least eight moderate Islamist rebel groups, after proposing a grand merger with any interested party in early January. Although talks briefly came to a close in mid-January over the troublesome issue of the Nusra Front’s allegiance to al-Qaida, the group’s leader Abu Mohammed al-Jolani now placed those ties as an issue on the table for negotiation. 

Al-Qaida has not disappeared, and neither has it been defeated.

The fact that this sensitive subject is now reportedly open for discussion is a significant indicator of how far the Nusra Front is willing to stretch its jihadist mores for the sake of integration in Syrian revolutionary dynamics. However, the al-Nusra Front's leader, Abu Mohammed al-Jolani, is a long-time Al-Qaeda loyalist and doesn't fit the profile of someone willing to break a religious oath purely for the sake of an opportunistic power play. It is therefore interesting that this secret debate inside Syria comes amid whispers within Salafi-jihadi and pro-al-Qaida circles that Zawahiri is considering “releasing” his affiliates from their loyalty pledges in order to transform al-Qaida into an organic network of locally-inspired movements—led by and loosely tied together by an overarching strategic idea.

Whether al-Qaida and its affiliates ultimately evolve along this path or not, the threat they pose to local, regional, and international security is clear. When compounded by ISIS’s determination to continue expanding and to conduct more frequent and more deadly attacks abroad, jihadist militancy looks well-placed to pose an ever present danger for many years to come. 

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