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The stakes could hardly be higher; the prize still tantalisingly out of reach. It is no exaggeration to say that the fate of many millions of people rests on the discovery of a vaccine for Covid-19 – the only sure escape route from the pandemic.

Yet the optimism that accompanied the launch of Oxford University’s human trials this week has to be put in context, and the hurdles facing the scientists need to be understood.

The ongoing spread of COVID-19 in Russia is leading to shortages of drugs against orphan diseases in…

Positive Phase III data for Recarbrio (imipenem/cilastatin/relebactam) have been announced by New Jersey,…

The US Food and Drug Administration has granted accelerated approval for Retevmo (selpercatinib) capsules…

Jorge Flores-Rojas, 44, an undocumented Mexican national, was sentenced to 24 years in prison by Chief Judge Robert J. Conrad, Jr. in Charlotte, N.C., for two counts of sex trafficking of minors and one count of interstate transportation of an adult for purposes of commercial sex. Flores-Rojas pled guilty to the charges on Oct. 7, 2008.

The Department announced that it has moved to intervene in a lawsuit filed in federal court in Jackson, Miss., challenging inaccessibility in Jackson’s public transportation system. The pending lawsuit, filed by 11 residents of Jackson with disabilities and two non-profit organizations that work on behalf of people with disabilities, alleges violations of the Americans with Disabilities Act and the Rehabilitation Act of 1973 (ADA).

The Department will not challenge a proposal by seven regional less-than-truckload (LTL) freight transportation companies to bid jointly and engage in other collaborative activity as part of their nationwide LTL truck transportation services joint venture.

Michael Wildridge, 41, pleaded guilty today to transportation and possession of child pornography and was sentenced to 10 years in prison.

The Department will require Ticketmaster Entertainment Inc. to license its ticketing software, divest ticketing assets and subject itself to anti-retaliation provisions in order to proceed with its proposed merger with Live Nation Inc.

The United States has reached a comprehensive settlement agreement with the city of Jackson, Miss., to improve access to public transportation for individuals with disabilities.

A federal judge in St. Louis has barred two St. Louis tax preparers and their businesses from certain conduct the Justice Department announced today

The Alaska Department of Transportation and Public Facilities has agreed to pay nearly $1 million to resolve allegations that it violated the Clean Water Act at numerous sites in Alaska

In response to a federal enforcement action for excessive train engine idling, the Massachusetts Bay Transportation Authority (MBTA) and the Massachusetts Bay Commuter Railroad Company (MBCR) will spend more than $2 million to reduce diesel locomotive emissions throughout the MBTA’s commuter rail system.

The Justice Department today announced a settlement agreement with AMC Entertainment Inc. to resolve a lawsuit filed under the Americans with Disabilities Act.

The Department of Justice announced today that it has resolved claims made by Stephen Ralston against the South Bend, Ind., Public Transportation Corporation (TRANSPO) under the Uniformed Services Employment and Reemployment Rights Act of 1994.

"On August 24, 2009, based on information the Department received pertaining to alleged CIA mistreatment of detainees, I announced that I had expanded Mr. Durham’s mandate to conduct a preliminary review into whether federal laws were violated in connection with the interrogation of specific detainees at overseas locations."

Rodger Dale DeVries, 73, a resident of Jenison, Mich., has pleaded guilty to illegally importing a polar bear trophy mount in 2007 from Canada into Michigan in violation of the Marine Mammal Protection Act.

Leonard Wasylyk, 49, pleaded guilty before U.S. District Judge Sue L. Robinson in the District of Delaware.

The Board of Immigration Appeals has dismissed the appeal of John (Ivan) Kalymon of Troy, Mich., who was ordered removed from the United States earlier this year because of his participation in lethal acts of Nazi-sponsored persecution of Jews during World War II.

Wright Brothers Construction Co., of Charleston, Tenn., and the Georgia Department of Transportation (GDOT) have agreed to pay a $1.5 million penalty and spend more than $1.3 million to offset environmental damages to resolve alleged violations of the Clean Water Act.

Leonard Wasylyk, 49, was also sentenced to lifetime supervised release and will be required to register as a sex offender in any jurisdiction in which he lives, works or attends school.

James Smiley, 27, Colton Partin, 21, and Kyle Montgomery, 21, all of Chattanooga, Tenn., pleaded guilty today in U.S. District Court in Chattanooga for launching fireworks at African-Americans who were congregated outside their apartment building.

Charles Kizer, 53, from Memphis, Tenn., was sentenced late Friday by U.S. District Judge Samuel H. Mays, Jr. to 10 years in prison for violating the Mann Act.

The Antitrust Division closed its investigations into Google Inc.’s acquisition of Motorola Mobility Holdings Inc., the acquisitions by Apple Inc., Microsoft Corp. and Research in Motion Ltd. (RIM) of certain Nortel Networks Corporation patents, and the acquisition by Apple of certain Novell Inc. patents.

Colton L. Partin, 22, of Apison, Tenn., Kyle C. Montgomery, 23, and James Smiley, 27, both of Chattanooga, Tenn., were sentenced today by Chief U.S. District Court Judge Curtis L. Collier. Smiley and Montgomery were sentenced to 12 months in prison and three years of supervised release for conspiring to intimidate African-Americans in the free exercise and enjoyment of housing rights secured to them by the laws of the United States. Partin was sentenced to 18 months probation, including six months home confinement. All three men will also serve 300 hours of community service. The men pleaded guilty on Jan. 6, 2012.

Anthony Mangione, 51, of Parkland, Fla., pleaded guilty today to one count of transportation of child pornography.

The Attorney General announced today the closure of the criminal investigations into the death of two individuals while in United States custody at overseas locations.

Sheila Birnbaum, Special Master of the September 11th Victim Compensation Fund (VCF), released the following statement on the final rule by the National Institute for Occupational Safety and Health (NIOSH) to include certain cancers into the World Trade Center Health Program.

A U.S. Customs and Border Protection (CBP) Officer, his girlfriend and an associate have been charged in Brownsville, Texas, for engaging in a multi-year bribery and alien smuggling operation along the U.S./Mexico.

Two former employees at the Marine Corps Logistics Base Albany (MCLB-Albany) have pleaded guilty to receiving bribes related to a scheme to funnel freight hauling business to a local transportation company resulting in the loss of millions of dollars to the United States government.

The owners and supervisor of Alpha Ambulance Inc. (Alpha), a now-defunct Los Angeles-area ambulance transportation company, have pleaded guilty in connection with an ambulance fraud scheme.

A Canadian man was arrested today in St. John, New Brunswick, Canada, on an extradition warrant requested by the United States for money laundering crimes related to the illegal importation and illegal trafficking of narwhal tusks.

The government has asked a federal court in California to issue an injunction shutting down the importation and sales activities of four California companies and six individuals in connection with their imports of illegal children’s products containing, among other things, lead, phthalates and small parts inappropriate for children under age three.

Sea Star Line LLC and Horizon Lines LLC have agreed to resolve allegations that they violated the False Claims Act by fixing the price of government cargo transportation contracts between the continental United States and Puerto Rico.

The Justice Department announced today the filing of a lawsuit against the state of Hawaii and the state of Hawaii Department of Transportation Airports Division (HDOT-Airports) alleging that the defendants discriminated against former employee Sherry Valmoja by subjecting her to sexual harassment in violation of Title VII of the Civil Rights Act of 1964.

Attorney General Eric Holder announced Tuesday that the Justice Department would formally support a proposal under consideration by the U.S. Sentencing Commission to allow certain individuals serving time in federal prison for nonviolent drug offenses to be eligible for reduced sentences.

RE/MAX Allegiance Relocation Services, a Virginia-based move management company, has agreed to pay the government $509,807 to resolve allegations that it violated the False Claims Act by overbilling for transportation services, the Department of Justice announced today

Natural product brands can boost trade show ROI by investing in PR to work with trade press via press releases and onsite interviews.

From : Communities>>Regulatory Open Forum
Yes, I think there were some previous posts where people uploaded Word versions you can get; just need to look around a little. ------------------------------ Richard Vincins RAC Vice President Global Regulatory Affairs ------------------------------

From : Communities>>Regulatory Open Forum
This message was posted by a user wishing to remain anonymous Why not use Adobe to fill out the form?  You will need it to compile the submission anyway.

From : Communities>>Regulatory Open Forum
This message was posted by a user wishing to remain anonymous When this was first issued we printed it out, filled in the answers with careful handwriting and then scanned it back in - which seemed to be perfectly acceptable. Since then we've converted their form to a fillable PDF.​

Supplies of the selective serotonin reuptake inhibitor, sertraline, are returning to stock after manufacturers reported “industry-wide” supply challenges, exacerbated by export bans and border closures implemented as a result of COVID-19. 

To read the whole article click on the headline

A manufacturer has announced plans to move production of hydroxychloroquine — currently being trialled as a COVID-19 treatment — to the UK from abroad to combat potential shortages.

To read the whole article click on the headline

San Francisco will allow certain businesses to reopen beginning May 18 as it eases its stay-at-home orders. But officials warn that they will keep track to make coronavirus infections don't spike.

By Karla L. Palmer —

Check important government schemes launched by the Ministry of Health & Family Welfare which are important to study for the UPSC (IAS) Prelims 2020 exam.

Check the most important topics of Economics for the preparation of UPSC (IAS) Prelims Exam 2020. All the important topics have been added after a detailed analysis of the latest UPSC Prelims 2020 Syllabus.