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Chemistry breakthrough could speed up drug development

Scientists have successfully developed a new technique to reliably grow crystals of organic soluble molecules from nanoscale droplets, unlocking the potential of accelerated new drug development.




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How to manipulate light on the nanoscale over wide frequency ranges

An international team has discovered an effective method for controlling the frequency of confined light at the nanoscale in the form of phonon polaritons (light coupled to vibrations in the crystal). The results have now been published in Nature Materials.




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Hydrogen blamed for interfering with nickelate superconductors synthesis

Prof. ZHONG Zhicheng's team at the Ningbo Institute of Materials Technology and Engineering has investigated the electronic structure of the recently discovered nickelate superconductors NdNiO2. They successfully explained the experimental difficulties in synthesizing superconducting nickelates, in cooperation with Prof. Karsten Held at Vienna University of Technology.




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Perspective: Rapid repurposing of drugs for COVID-19

Given the rapid spread of COVID-19 and its relatively high mortality, filling the gap for coronavirus-specific drugs is urgent.




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Perspective: Rapid COVID-19 vaccine development

When seeking the fastest pathway to a vaccine to prevent coronavirus disease 19 (COVID-19), defining the stakes and potential hurdles is critical, says Barney Graham in this Perspective.




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USF researchers find human-driven pollution alters the environment even underground

The Monte Conca cave system in Sicily is showing signs of being altered by pollution from above.




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International research improves quality of CT scan imagery

Computerized tomography (CT) is one of the most effective medical tests for analysing the effects of many illnesses, including COVID-19. An international team has developed a new method that improves the quality of the images obtained from CT scans. The algorithm, tested on simulated data, enables them to distinguish different body's tissue types better and opens the door to lowering the doses of radiation to which patients are exposed during this type of test.




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The Lancet: New triple antiviral drug combination shows early promise for treating COVID-19 in phase 2 randomized trial

A two-week course of antiviral therapy with interferon beta-1b plus lopinavir-ritonavir and ribavirin, started within 7 days of showing COVID-19 symptoms, is safe and more effective at reducing the duration of viral shedding than lopinavir-ritonavir alone in patients with mild to moderate illness, according to the first randomized trial of this triple combination therapy involving 127 adults (aged 18 and older) from six public hospitals in Hong Kong.




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COVID-19 and the role of tissue engineering

Tissue engineering has a unique set of tools and technologies for developing preventive strategies, diagnostics, and treatments that can play an important role during the ongoing COVID-19 pandemic.




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Discovered a multilayer haze system on Saturn's Hexagon

The most extensive system of haze layers ever observed in the solar system have been discovered and characterised on the planet Saturn.




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Fishing can disrupt mating systems

In many fish species body size plays an important role in sexual selection. Large individuals are preferred mating partners because they can enhance offspring survival by providing better quality resources than small individuals. While large females and males are often favored by sexual selection, fishing targets and removes these reproductively superior individuals. Academy Research Fellow Silva Uusi-Heikkilä discusses in her recent literature review the implications fisheries selection might have on sexual selection, individual reproductive success and population viability.




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Neandertals were choosy about making bone tools

Evidence continues to mount that the Neandertals, who lived in Europe and Asia until about 40,000 years ago, were more sophisticated people than once thought. A new study from UC Davis shows that Neandertals chose to use bones from specific animals to make a tool for specific purpose: working hides into leather.




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Understanding the impact of COVID-19 in pets and livestock

A new paper identifies the critical need for research on the ability of the COVID-19 virus to infect certain animal species, the transmissibility of infection between humans and those animals, and the impact infection could have on food security and the economy.




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Burning out in silence

Russian companies still pursue authoritarian leadership styles, and employees often avoid articulating their concerns and complaints to management. Together with chronic stress and work-family imbalance, this can often result in emotional burnout. This is the conclusion of a study by researchers from North Dakota State University and HSE University.




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Stroke evaluations drop by nearly 40% during COVID-19 pandemic

A study from Washington University School of Medicine in St. Louis has found that stroke evaluations fell by nearly 40% during a period of the COVID-19 pandemic, suggesting that many stroke patients are not seeking potentially life-saving medical treatment.




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Talent is key to school turnarounds

New research has shown that the key to implementing successful reform in low-performing schools is hiring and retaining effective principals and teachers.




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Neighborhood and cognitive performance in middle-age: Does racial residential segregation matter?

A study at Columbia University Mailman School of Public Health found that black subjects who were exposed to highly segregated neighborhoods in young adulthood exhibited worse performance in cognitive skills in mid-life. This outcome may explain black-white disparities in dementia risk at older age.




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Transporting energy through a single molecular nanowire

Photosynthetic systems in nature transport energy very efficiently towards a reaction center, where it is converted into a useful form for the organism. Scientists have been using this as inspiration to learn how to transport energy efficiently in, for example, molecular electronics. Physicist Richard Hildner from the University of Groningen and colleagues have investigated energy transport in an artificial system made from nanofibres. The results were published in the Journal of the American Chemical Society.




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Forecasting urbanization

A new global simulation model offers the first long-term look at how urbanization -- the growth of cities and towns--will unfold in the coming decades. The research team projects the total amount of urban areas on Earth can grow anywhere from 1.8 to 5.9-fold by 2100, building approximately 618,000 square miles.




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Epithelial GPS: Position of RNAi machinery is associated with epithelial identity

Researchers at the Medical University of South Carolina show in a new report that the RNA interference machinery, normally thought to reside in the nucleus or cytoplasm, predominantly localizes to these apical junctions and influences cell biology in the colon. Interestingly, in colon tumors, this localization is dysregulated and may shift the balance of RNAs to promote tumorigenesis.




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Immune system discovery paves way to lengthen organ transplant survival

A new discovery in mice shows the innate immune system has 'memory,' previously thought to be a unique feature of the adaptive immune system. Blocking this memory prevented transplanted organs from being rejected, providing a way to more specific drugs that could lengthen organ transplant survival.




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Plasma medicine research highlights antibacterial effects and potential uses

As interest in the application of plasma medicine -- the use of low-temperature plasma (LTP) created by an electrical discharge to address medical problems -- continues to grow, so does the need for research advancements proving its capabilities and potential impacts on the health care industry. Across the world, many research groups are investigating plasma medicine for applications including cancer treatment and the accelerated healing of chronic wounds, among others.




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Promising study by Texas A&M scientists offers hope for Menkes disease patients

A Texas A&M AgriLife Research team has good news for patients with copper-deficiency disorders, especially young children diagnosed with Menkes disease.




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To err is human, to learn, divine

New research describes a new model for how the brain interprets patterns in complex networks. They found that the ability to detect patterns stems in part from the brain's desire to represent things in the simplest way possible and that the brain is constantly weighing the pressures of complexity and simplicity when making decisions.




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To climb like a gecko, robots need toes

Researchers know the secret to geckos' ability to walk on the ceiling: their hairy toes. But how do they use their five toes per foot to adjust to gravity when running horizontally along walls. At UC Berkeley, biologists used high-speed cameras to record how geckos orient their toes with shifting weight, especially when encountering slippery or rough patches, and found a remarkable ability to adjust toe orientation to stick and peel while running full speed.




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New study shines light on mysterious giant viruses

In recent years, giant viruses have been unearthed in several of the world's most mysterious locations, from the thawing permafrost of Siberia to locations unknown beneath the Antarctic ice. But don't worry, 'The Thing' is still a work of science fiction. For now.




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OSU study shows grange a 'natural partner' for expanding health outreach

In the ongoing struggle to address health care disparities in rural communities across the US, a recent study found that the perfect partner may be hiding in plain sight. The grange, founded in 1867, is a community-based organization that is likely familiar to anyone who's spent time in a small town. In addition to political advocacy on behalf of farmers, the grange's missions around community and family also align closely with the goals of public health.




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Individualized mosaics of microbial strains transfer from the maternal to the infant gut

Researchers have used a microbiome 'fingerprint' method to report that an individualized mosaic of microbial strains is transmitted to the infant gut microbiome from a mother giving birth through vaginal delivery. They detailed this transmission by analyzing existing metagenomic databases of fecal samples from mother-infant pairs, as well as analyzing mouse dam and pup transmission in a germ-free, or gnotobiotic, mouse model, where the dams were inoculated with human fecal microbes.




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The role of European policy for improving power plant fuel efficiency

A new study published in the Journal of the Association of Environmental and Resource Economists investigates the impact of the European Union Emissions Trading Scheme (EU ETS), the largest international cap-and-trade system for greenhouse gas emissions in the world, on power plant fuel efficiency.




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Seahorse and pipefish study by CCNY opens window to marine genetic diversity May 08, 2020

The direction of ocean currents can determine the direction of gene flow in rafting species, but this depends on species traits that allow for rafting propensity. This is according to a City College of New York study focusing on seahorse and pipefish species. And it could explain how high genetic diversity can contribute to extinction in small populations.




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Pediatric coronavirus disease (COVID-19) x-ray, CT in review of new lung disorders

Although the clinical symptoms of SARS, H1N1, MERS, EVALI, and COVID-19 may be nonspecific, some characteristic imaging findings are emerging, says the American Journal of Roentgenology (AJR). Careful evaluation of the distribution, lung zone preference, and symmetry of the abnormalities with an eye for a few unique differentiating imaging features can allow radiologists to offer a narrower differential diagnosis in pediatric patients, leading to optimal patient care.




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'Detailed' plans being drawn up to restart economy, Jenrick says as testing falls below 100,000 for fourth day

The update comes after Prime Minister Boris Johnson confirmed he would set out a lockdown exit strategy on Sunday.




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Debenhams accused of 'stealing' as retailer demands 90% discount on clothes from suppliers already at UK ports

ITV News has seen correspondence from Debenhams’ administrator to Bangladeshi suppliers demanding a 90% discount on garments orders.




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Charity warns of 'mental illness timebomb' as calls increase by 200%

The number of callers to the charity SANE’s telephone helpline has increased by 200 percent since the lockdown began.




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Hospices still denied access to PPE as Health Secretary insists government is doing 'as much as we can'

One hospice ITV News spoke to is three days away from running out of protective gowns needed to treat patients with coronavirus.




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New Banksy artwork pays tribute to NHS heroes

The piece, called Game Changer, is on display in a corridor at Southampton General Hospital.




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UK Weather Forecast: A fine evening with clear skies & late, low sunlight

A fine end to the day with late sunshine & clear skies




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Former Scotland rugby captain takes on walking challenge to raise money for NHS

A former Scotland rugby captain, who suffered life changing injuries in a car crash, is walking to raise money for the NHS.




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Kraftwerk co-founder Florian Schneider dies aged 73

Florian Schneider, co-founder of the pioneering electronic music group Kraftwerk, has died at the age of 73.




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Four-year-old with cancer reunited with father after seven weeks kept apart in lockdown

Mila Sneddon hasn't seen her father in seven weeks in order to keep her safe during coronavirus lockdown.




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Care company launch own We Care badge to support workers during coronavirus pandemic

A North East based care provider, Wellburn Care Homes, has launched their own We Care badge aiming to show support for care workers.




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'Our souls are coming to the fore': The impact of pandemic on faith

Though each religion has faced different challenge, they share the view the lockdown has presented us with insight we might not have had.




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'Almost criminal' coronavirus testing isn't available for everyone, former Prime Minister Gordon Brown says

Former Prime Minister Gordon Brown has called for "more than 200,000" coronavirus tests to be carried out.




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UK Weather Forecast: A chilly night with a slight frost in the east

Cold enough for a slight frost in places




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Coronavirus: 'Delays in action on care home crisis cost thousands of lives', documents reveal

Data which identified a massive in Covid-19 was sent to ministers a month before the government's Care Home Action Plan was published.




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Man arrested on suspicion of attempting to murder police officer

The officer’s injuries are not thought to be life-threatening.




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Medieval arrows caused similar injuries to gunshots, say archaeologists

Arrows fired from longbows could penetrate right through the human skull creating small entry and large exit wounds.




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Eating disorder sufferer’s anguish shines light on mental health provision

Emily Nuttall, 26, has sought help from charities such as Mind and Beat to help her cope with mental health problems during lockdown.




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People want to see green spaces prioritised after lockdown – poll

Survey finds people are appreciating their local parks, countryside and green belt more.




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Portrait of Dame Vera Lynn unveiled to mark VE Day

The oil on canvas painting is entitled The Enduring Sweetheart.