Hidden in the thick foliage of tropical forests a subfamily of colorful beetles–the Chrysomelidae–may be hiding the secrets to the earliest stages of social behavior. […]

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(A male golden-collared manakin cleans up his display area.) Few of us would find a marriage proposal made amidst dirty dishes and messy clutter particularly […]

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The positional change of nitro­gen-7 of the RNA constituent guanosine to the bridgehead position-5 leads to the base-modified nucleoside 5-aza-7-de­aza­guanosine. Contrary to guanosine, this mol­ecule cannot form Hoogsteen base pairs and the Watson–Crick proton donor site N3—H becomes a proton-acceptor site. This causes changes in nucleobase recognition in nucleic acids and has been used to construct stable `all-purine' DNA and DNA with silver-mediated base pairs. The present work reports the single-crystal X-ray structure of 7-iodo-5-aza-7-de­aza­guanosine, C10H12IN5O5 (1). The iodinated nucleoside shows an anti conformation at the glycosylic bond and an N conformation (O4'-endo) for the ribose moiety, with an anti­periplanar orientation of the 5'-hy­droxy group. Crystal packing is controlled by inter­actions between nucleobase and sugar moieties. The 7-iodo substituent forms a contact to oxygen-2' of the ribose moiety. Self-pairing of the nucleobases does not take place. A Hirshfeld surface analysis of 1 highlights the contacts of the nucleobase and sugar moiety (O—H⋯O and N—H⋯O). The concept of pK-value differences to evaluate base-pair stability was applied to purine–purine base pairing and stable base pairs were predicted for the construction of `all-purine' RNA. Furthermore, the 7-iodo substituent of 1 was functionalized with benzo­furan to detect motional constraints by fluorescence spectroscopy.

Simon L. Bullock
Apr 6, 2020; 133:jcs245134-jcs245134
Meeting Report

Focused attention by world leaders is needed to address the substantial challenges posed by disposal of spent nuclear fuel from reactors and high-level radioactive waste from processing such fuel for military or energy purposes.

By expending too many resources to inspect cleaner low-emitting vehicles, coupled with a lack of effective ways to deal with the dirtiest ones, states are missing opportunities to reduce air pollution.

The 2011 Fukushima Daiichi nuclear accident should serve as a wake-up call to nuclear plant operators and regulators on the critical importance of measuring, maintaining, and restoring cooling in spent fuel pools during severe accidents and terrorist attacks, says a new report from the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine urges Congress, federal and state agencies, and regulatory institutions to significantly increase their support for innovation for what the report’s study committee calls “increasingly clean” electric power technologies – nuclear power, carbon capture and storage, and renewables such as solar and wind. Some of these technologies have seen recent cost and price declines and are cost-competitive in certain locations.

The National Academies Committee on Genetically Engineered Crops - Past Experiences and Future Prospects authored an almost 600-page landmark report, released in May 2016. It was perhaps the most comprehensive analysis of genetically engineered crops to date.

The U.S. DRIVE Partnership – a government-industry partnership that fosters the development of precompetitive and innovative technologies for clean and efficient light-duty vehicles – has made significant progress in many technical areas including advanced combustion technologies, durability and cost of hydrogen fuel cells, and electric drive systems such as motors, power electronics, and batteries, says a new report by the National Academies of Sciences, Engineering, and Medicine.

The U.S. Global Change Research Program (USGCRP) asked the National Academies of Sciences, Engineering, and Medicine to review the draft Fourth National Climate Assessment (NCA4) – a congressionally mandated report that evaluates the state of climate science and the broad range of impacts of climate change in the United States every four years – and the draft Second State of the Carbon Cycle Report (SOCCR2) – a report that feeds into the overall assessment process developed by the USGCRP.

The science questions that could be answered by an electron ion collider (EIC) – a very large-scale particle accelerator – are significant to advancing our understanding of the atomic nuclei that make up all visible matter in the universe, says a new report by the National Academies of Sciences, Engineering, and Medicine.

A new report from the National Academies of Sciences, Engineering, and Medicine recommends changes in the way that the U.S. Department of Energy manages science and technology (S&T) development in order to accelerate the cleanup of radioactive waste and contaminated soil, groundwater, and facilities at U.S. nuclear weapons sites.

A new report from the National Academies of Sciences, Engineering, and Medicine – which reviews a separate report by a federally funded laboratory that examines options for treating low-activity radioactive waste at the Hanford Nuclear Reservation -- is available for public comment until Oct. 31.

The U.S. National Academies recognize the significance of the opioid crisis and have been at the forefront of efforts to advise our nation on how to combat it.

Autonomous vehicles (AV) took center stage at the Chair’s Luncheon of the Transportation Research Board’s annual meeting today.

In 1943, the town of Hanford in Washington State was selected by the Manhattan Project to be home to the first full-scale plutonium production reactor in the world.

Exide begins to remove lead-polluted soil on Monday morning at a house on the 1200 block of La Puerta Street in Boyle Heights.; Credit: Maya Sugarman/KPCC

All five members of the Los Angeles County Board of Supervisors have signed a letter imploring California Gov. Jerry Brown to intervene in the state’s handling of contamination around the Exide Technologies plant in Vernon.

The letter criticizing the state’s “piecemeal approach to an urgent environmental hazard” comes as workers paid for by Exide are removing lead-contaminated topsoil from two homes near the intersection of Olympic and Indiana avenues in L.A. 

Signed Tuesday, the letter asks for “guaranteed state funding to immediately begin testing” at 37 more homes also sampled, but to less specific degrees, during November 2013. In the words of the board, “further testing and remediation of the other 37 homes has not been confirmed and may not begin until at least October 2014 because Exide has not yet agreed to comply with DTSC directives issued last March.”

The supervisors also say the state has “reneged” on its commitments to test for lead inside the homes as well as outside.

The Department of Toxic Substances Control says that the two homes workers are at this week will be cleaned inside and out — even without indoor testing.  The DTSC’s Rizgar Ghazi said Monday that crews will use HEPA filters, vacuums and shampooing equipment on “basically any flat surface” inside the two residences.

Read the L.A. Board of Supervisors’ letter to Gov. Brown here:

http://www.scribd.com/doc/236655733/LA-County-Supervisors-Letter-to-Gov-Brown-8-12-14

This content is from Southern California Public Radio. View the original story at SCPR.org.

A 2018 exhibit at the Billy Ireland Cartoon Library & Museum at Ohio State University celebrated the artistic legacy of MAD magazine.; Credit: Andrew Welsh-Huggins/AP

The funny, freckled face of Alfred E. Neuman is more or less retiring.

One of the last widely circulated print satirical magazines in America will leave newsstands after this year, according to sources at DC Comics, which publishes MAD magazine.

While the Harvard Lampoon remains in business, The Onion hasn't been in print since 2013. The once-influential Spy was a casualty of the 1990s.

At MAD's peak in the early 1970s, more than 2 million people subscribed to it, both for its pungent political humor and deeply adolescent jokes.

In 2017, that number had reportedly dropped to 140,000.

MAD isn't completely shutting down, but it will be radically downsized and changed.

Readers will only be able to find the 67-year-old humor magazine at comic book stores and through subscriptions.

After issue No. 10 this fall, there will no longer be new content, except for end-of-year specials which will be all new. Starting with issue No. 11, the magazine will feature classic, best-of and nostalgic content, repackaged with new covers.

This content is from Southern California Public Radio. View the original story at SCPR.org.

The engineered Dominguez Gap Wetlands in Long Beach filters stormwater and runoff from the Los Angeles River, then the water is siphoned under the river to a spreading ground to the west.; Credit: Sharon McNary/KPCC

Angelenos are used to looking up Heal the Bay's annual beach water quality report card each May as we search out the cleanest places to swim and surf.

Now, the environmental advocacy group is focusing on a new target — the often polluted water that flows into the ocean from the mountains and across the L.A. Basin.

In a first-ever report, it concludes the managers of 12 watersheds from Malibu to Long Beach are making too little progress toward cleaning up this major source of pollution in the Pacific.

This content is from Southern California Public Radio. View the original story at SCPR.org.

February satellite readings in the troposphere (the lower atmosphere) of nitrogen dioxide (NO2), a pollutant primarily from burning fossil fuels, show a dramatic decline compared to early January when power plants were operating at normal levels.; Credit: /NASA Earth Observatory

As China seeks to control the spread of COVID-19, fewer cars are driving, fewer factories are running and — in some places — skies are clearer.

Air pollution levels have dropped by roughly a quarter over the last month as coal-fired power plants and industrial facilities have ramped down so employees in high-risk areas can stay home. Levels of nitrogen dioxide, a pollutant primarily from burning fossil fuels, were down as much as 30%, according to NASA.

"It is an unprecedentedly dramatic drop in emissions," says Lauri Myllyvirta, lead analyst at the Centre for Research on Energy and Clean Air, who tallied the reductions. "I've definitely spoken to people in Shanghai who said that it's been some of the most pristine blue skies that they remember over the winter."

Myllyvirta estimates that China's carbon emissions have dropped by a quarter over the same period. While that's a tiny fraction of its overall annual emissions, it's substantial in a worldwide context, since China is the largest emitter of greenhouse gases.

There's potentially a health benefit — although any gains due to a drop in pollution are set against the toll taken by the coronavirus outbreak.

Air pollution is estimated to contribute to more than 1 million premature deaths in China each year. Fine particle pollution, also known as PM 2.5, can enter the bloodstream through the lungs and has been linked to asthma attacks, heart attacks and respiratory problems.

Even a short-term reduction in air pollution can make a difference.

"There is no question about it: When air quality improves, that will be associated with a reduction in health-related problems," says Jim Zhang, professor of global and environmental health at Duke University.

Zhang says that was evident during the 2008 summer Olympics in Beijing. To help improve the air, government officials shut factories and dramatically limited car travel before and during the games. Levels of some air pollutants dropped by half.

He and colleagues studied a group of young men and women in Beijing and found that during that time period, their lung and cardiovascular health improved. He also followed pregnant women.

"What we found is that the kids whose mothers had a third trimester pregnancy during the Olympics when the air quality was better, their birth weight was substantially higher than the kids who were born a year before and a year later," he says.

But health specialists sound a cautionary note.

"It would be a mischaracterization to say that the coronavirus was beneficial to health because of these air pollution reductions," says Jill Baumgartner, associate professor and epidemiologist at McGill University.

"The health impacts from the virus itself, the stress on the health-care system, the stress on people's lives — those health impacts are likely to be much greater than the short-term benefits of air pollution on health," she says.

Baumgartner says people with health issues other than COVID-19 may have avoided seeing doctors during the outbreak or potentially couldn't receive treatment they needed in areas with overtaxed health systems.

Those isolated at home and avoiding crowds may also have been exposed to more indoor air pollution.

"People spent a lot more time indoors and it's possible that they were exposed to higher levels of indoor tobacco smoke," Baumgartner says. "Or in the suburban areas, it's possible that they were using their traditional wood or coal stoves for heating."

Not all cities have experienced the recent improvements. In mid-February, Beijing saw a spike in pollution due to local weather patterns trapping air in the region.

The drop in air pollution and carbon emissions is also likely to disappear as Chinese industry ramps up again in an attempt to offset its economic losses.

"If you think back to the global financial crisis, the immediate impact was for China's emissions to fall," says Myllyvirta. "But then the government response was to roll out the biggest stimulus package in the history of mankind that then drove China's emissions and global emissions up for years."

This content is from Southern California Public Radio. View the original story at SCPR.org.

Two judges appointed by President Trump to the District of Columbia Circuit Court of Appeals prevailed Tuesday in a ruling that clears the way for the executions of four inmates.

The only dissenter in the 3-2 ruling was Judge David Tatel, an appointee of former President Bill Clinton. The judges were reviewing a lower court's injunction that had blocked the scheduled executions.

The decision was seen as a win for Trump's Justice Department, which issued new guidelines last July that would have allowed the federal government to carry out its first executions in 16 years.

The fates of the four men remain unresolved because their death sentences were sent back to the lower court for further proceedings.

In December, the U.S. Supreme Court declined the Justice Department's request to vacate the lower court's injunction that scuttled the planned executions.

At issue is the question of whether the condemned men should be put to death by the injection of only one barbiturate — pentobarbital — as called for in the Justice Department's July 2019 memo.

Many of the 28 states where the death penalty is still legal require a lethal injection cocktail containing not one but three barbiturates. Those states include Indiana, where the scheduled executions were to take place.

Pharmaceutical companies have stopped producing at least one of the three drugs used in that lethal mixture, and several botched executions have resulted from some states using untested formulas.

The 1994 Federal Death Penalty Act calls for executions to be carried out "in the manner prescribed by the law of the State in which the sentence is imposed."

Judge Gregory Katsas argues in his majority opinion that the "manner prescribed" simply refers to the method of execution rather than the protocols each state follows in carrying out each kind of execution.

"The government says that 'manner' here means 'method'," Katsas writes, "such that the FDPA regulates only the top-line choice among execution methods such as hanging, electrocution, or lethal injection. In my view, the government is correct."

Judge Neomi Rao, in a concurring opinion, argues that while the word "manner" refers not only to the method of execution, it cannot be interpreted in isolation. "It is a broad, flexible term," she says, "whose specificity depends on context."

In his dissent, Tatel says the best understanding of the 1994 statute is that it "requires federal executions to be carried out using the same procedures that states use to execute their own prisoners.

"Had Congress intended to authorize the Attorney General to adopt a uniform execution protocol," Tatel argues, "it knew exactly how to do so."

This content is from Southern California Public Radio. View the original story at SCPR.org.

Homeless advocates erected a line of tents outside the Echo Park office of City Councilman Mitchell O'Farrell Feb. 12, 2020 to pressure him into meeting with them.; Credit:

Members of several groups of homeless advocates from across Los Angeles converged on a homeless encampment at the north end of   Echo Park Lake on Feb. 12 to protest the routine weekly litter collection.

A cleanup crew assisted by park rangers and city police officers did a once-through the campsite for miscellaneous trash, followed closely by a chanting and critical crowd of protesters.

The homeless advocates had erected extra tents that morning in protest of what they consider invasive cleanups. They also were trying to get City Councilman Mitchell O'Farrell to agree to meet with them as a group, same as he has met with other local organizations of homeowners and residents.

O'Farrell's spokesman Tony Aranga had insisted staffers were willing to meet with individuals to address their housing and other support needs.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Today’s post is by Owen Paul, who is a Student Ambassador Technical Program Specialis. He himself was a student ambassador before joining MathWorks, and he was featured in the Community... read more >>

CCleaner is a program that will scan your computer for temporary files or private browser information and deletes it from your computer.  This allows you to keep your computer running efficiently, while protecting your sensitive information. [...]

AdwCleaner is a free program that searches for and deletes Adware, Toolbars, Potentially Unwanted Programs (PUP), and browser Hijackers from your computer. By using AdwCleaner you can easily remove many of these types of programs for a better user experience on your computer and while browsing the web. [...]

Larry Ellison, CEO of Oracle Corporation, gestures as he makes a speech during the New Economy Summit 2014 in this file photo taken in Tokyo on April 9, 2014. The company said Thursday, September 18, 2014, that Ellison would step aside as CEO and become chairman and chief technology officer.; Credit: TORU YAMANAKA/AFP/Getty Images

Oracle says Larry Ellison is stepping aside as CEO of the company he founded. The business software maker promoted Safra Catz and Mark Hurd to replace him as co-CEOs.

Ellison will reclaim the title of chairman at Oracle and is also taking the role of chief technology officer. Oracle says Ellison wants to focus on product engineering, technology development and strategy. Jeff Henley, Oracle's chairman since January 2004, is now its vice chairman.

Catz and Hurd were co-presidents of the Redwood Shores, California, company. Catz will be in charge of the company's manufacturing, finance and legal functions. Hurd will be in charge of sales, service, and other global business units.

Ellison founded Oracle Corp. in 1977 and was its chairman from May 1995 to January 2004.

Sustainable consumption and production (SCP) programmes are frameworks to systemically develop sustainability. New research has analysed three national SCP programmes in the UK, Sweden and Finland and concluded that, rather than provide a strong roadmap for sustainability, they tend to be a toolbox of good but scattered initiatives.

A recent study has assessed the lifecycle environmental impact during the production and use phase of three battery types for plug-in hybrid (PHEV) and full performance battery electric vehicles (BEV). The study indicates that newer lithium-ion (Li-ion) technologies outperform current nickel-metal hydride (NiMH) batteries and identifies processes contributing to 13 environmental impacts

Fragments of crushed rock released into the ocean during oil and gas exploration can physically bury organisms that live on the seafloor, accounting for 55% of offshore drilling???s environmental impact, according to a recent study. To allow more informed marine policy decisions, this physical impact must be recognised alongside the impact of chemicals released in drilling waste.

Researchers have discovered high levels of plastic particles and fibres, as well as black carbon (BC), which is formed by the incomplete burning of fossil fuels, in the waters of the Jade Bay, an inshore basin off the coast of Germany in the Southern North Sea. The concentration of suspended particles are of concern because they have the potential to be ingested by fish and other marine life, and enter the food chain.

A new study provides recommendations to reduce the environmental impact of personal hygiene and cleaning products on the environment. Researchers undertook life-cycle assessments of products including detergents, soaps and toilet cleaners, and compared their environmental footprints looking at different types of environmental damage.

As the development of nanomaterials increases, a recent study recommends combining life cycle analysis and risk assessment to improve our understanding of the potential environmental and human health impacts of products containing nanomaterials.