For many kids, middle school is a fraught time. Friendships are forged and broken; bodies begin to change in sometimes uncomfortable ways. For Zenobia July, starting middle school is far more complicated than it is for most of her peers.

Imagine there's a virus living inside you. This virus is harmless. Most of the time. But then, something causes it to change and it could kill you unless you take one dose of a powerful drug. Now imagine there is a critical shortage of this drug. This is the scary scenario at the heart of the debut novel by Hanover resident and Dartmouth professor Charles Wheelan. It's called The Rationing, but this isn't a book about a disease. It's a political satire about how the United States government handles the unfolding public health crisis. Personalities clash. Political ambitions get in the way of productive discussion. Fake News opportunists muddy the waters and foreign countries take advantage of a vulnerable United States. Charles Wheelan joined NHPR's Peter Biello to talk about his new book.

Freeman Colby was a young schoolteacher from New Hampshire who joined the Union Army during the American Civil War. For the first nine months, Colby kept detailed notes of his service and wrote to his family members. Marek Bennett of Henniker drew on these rich resources for his graphic novel, The Civil War Diary of Freeman Colby. In that volume, Bennett stuck close to Colby's exact language. Recently, he's published Volume II, in which he takes some liberties and draws on new sources for inspiration. NHPR's Peter Biello sat down with Marek Bennett to talk about Volume II.

Miriam Levine's new collection of poetry is, as she describes it, a book about loss and consolation. In Saving Daylight, poems recall small moments: a chance meeting outside a theater, an encounter with a mosquito, watching a harmless spider walk across someone's hair. Levine lives in Concord for part of the year, and she sat down with NHPR's All Things Considered Host Peter Biello to chat about her new collection.

In Jennifer Militello's debut memoir, Knock Wood, time moves in more than one direction. The relationship between cause and effect is upended as Militello explores her memories of illicit love, domestic violence and dangerous influences. Militello, is the author of several books of poetry, and she teaches at New England College. She sat down with All Things Considered host Peter Biello to talk about her new book.

For much of human history, human beings have waged war against each other. In the new novel by Marko Kloos, that tendency to wage war remains as strong as ever more than a thousand years into the future. Aftershocks is an adventure story as well as a portrait of a technologically-advanced civilization struggling to maintain the peace after a devastating war. Kloos spoke with NHPR’s Peter Biello.

This week marked the launch of the second annual edition of The People's Book, a collection of literary works and visual art created by New Hampshire writers and artists.

When Joe Hill launched his career as a writer, he didn't want anyone to know about his famous writer parents, Stephen and Tabitha King. Rather than ride their coattails, he wanted to find success on his own—thus the pen name, Joe Hill.

Writer Stacia Tolman worked for many years as a high school English teacher at a private school in New Hampshire’s Monadnock region.

Novelist Alex Myers came out as transgender in the mid-90s, when society's understanding of what it means to be transgender was less clear than it is today.

If you've ever been on a college campus or a public park, you may have seen desire lines. Those are those well-worn paths carved by travelers who, for whatever reason, preferred a route that diverged from the ones carefully cured in concrete by city or campus planners.

When New Hampshire author John Brighton was six years old, his family bought a lakeside farm in Washington, a small town in New Hampshire's Sullivan County.

When Cindy Copeland was in seventh grade in the early 1970s, an English teacher encouraged her to become a writer. Shortly after that, the Keene resident landed an internship as a “cub reporter” with a local journalist, following her to public meetings and learning how question people powerful people—most of them men. And Cindy did all this while navigating the tricky minefield of fraught friendships, cliques, and bullying that so often characterize life in junior high.

Alexandria Peary is New Hampshire’s new poet laureate, and she’s ramping up her work as the state’s official advocate for poetry and the literary arts more broadly. As part of her work as poet laureate, she’s been reading work sent to her by New Hampshire poets.

One day, while hiking in the Georgia mountains, a couple finds the bones of a human body buried many years ago. The discovery prompts a search for answers: why was this person killed? Who did it? And how many more bodies are hidden in these hills?

In Concord-native Meredith Tate’s new novel, a young woman is kidnapped after a drug deal goes badly. To summon help, she has an out-of-body experience. Her quest to give her sister clues about where she is and how she got there serves as the central action of the book, which is called The Last Confession of Autumn Casterly. Tate spoke about it with NHPR's Peter Biello.

The history of school desegregation in America has long been centered around the southern United States.

The flute-playing pop star celebrates self-acceptance on her latest album, Cuz I Love You. "About 10 years ago, I made the decision that I just wanted to be happy with my body," she says.

An Asian elephant named Mary, who lives at the Berlin Zoo learned how to wash herself clean using a hose as a flexible shower head.

In the event of a global crisis and deterioration of relations between the United States and China, the Central Bank of Russia will have to implement its risk scenario in which the bank will have to use the National Welfare Fund (NWF). The liquid part of the fund — the part that is available for spending — will be exhausted already in 2025, the Central Bank of Russia said in its report titled "Main Directions of the Unified State Monetary Policy." A global crisis may occur against the backdrop of high interest rates and the imbalance in global financial markets, Central Bank analysts believe.

Army General Pavel Popov, former Deputy Minister of Defense of Russia, was detained. He appears on the fraud case related to Moscow's Patriot Park. General Popov is accused of fraud on an especially large scale. According to the investigation, in 2021-2024, while he was responsible for the development, maintenance, and operation of the Patriot Park, he enriched himself at the expense of this institution — he used building materials to build his own house in the Krasnogorsk District (Moscow region) and forced park employees to work at his three-hectare dacha for free. According to the Investigative Committee, the director of the park, Vyacheslav Akhmedov, and deputy head of the Main Directorate for Innovative Development of the Ministry of Defense, Vladimir Shesterov, were also involved in the fraudulent scheme. General Pavel Popov was detained based on their testimony. Akhmedov and Shesterov said that they received money following the general's orders and paid him about three million rubles.

While discounts and sales events have long been associated with holiday shopping, new data from e-commerce provider Visualsoft reveals that consumers are motivated by more than just deep discounts when it comes to their seasonal and gifting purchases.

Austria's Raiffeisen Bank International considers selling the Russian division or withdrawing it from the structure of the group. Raiffeisen's "daughter" will continue running "certain banking activities" in Russia to maintain license. At the moment, the bank can not get rid of all of its business in Russia, but is striving for this to happen, RBI CEO Johann Strobl said. The RBI Group in Russia is represented by Raiffeisenbank, as well as leasing, insurance and management companies. The company's subdivisions employ over 9,000 people.

2022 was the second highest year of activity in the global self-checkout market, according to a brand-new report from RBR Data Services, a division of Datos Insights. Global EPOS and Self-Checkout 2023 shows that with an ever-wider range of retailers embracing the technology, competition in the market remains fierce.

Within the next twelve months, kiosks will be mainstream in the UK quick service restaurants (QSR), fast food and the casual dining market, according to the first UK research into consumer views and hospitality sector plans.

The market for self-ordering kiosks is booming, as restaurant operators seek to meet consumer demand for self-service.

By Ed Smith, freelance journalist

Self-checkouts have proven to be an increasingly popular option for shoppers to take control of their own scanning of items. It can feel a little quicker and allows you to scan then pack your goods at your own pace rather than trying to keep up with a cashier.

Janam Technologies, provider of rugged mobile computers and contactless access solutions, has introduced the newest addition to its Guardian family of access management hardware solutions.

The Ergonomic Solutions Group, the designer and manufacturer of technology mounting solutions, has launched the SpacePole Kiosk – described as a multifunctional platform with maximum flexibility for a wide range of self-service applications including self-check-in/check-out, self-ordering, endless aisle, product display & advertising, ticketing, click & collect and many more.

Doddle, the global e-commerce technology provider, has introduced a range of self-service kiosks to its solution portfolio, enabling retailers and carriers to address the challenge of online returns. 

imageHOLDERS’ bespoke kiosk technology has helped ViewPoint Feedback develop a new range of touchless self-service solutions ­- ensuring customers, employees, patients and students continue to leave vital real-time responses.

By Adrian Stokes, freelance writer.

Ever wondered how some retail stores seamlessly update their product prices in real-time, avoiding the hassle of manually switching out paper tags on shelves? Discover how electronic shelf labels work and how they can boost your sales and customer satisfaction.

Facebook Marketplace has become a popular platform for buying and selling goods, from used cars to gaming systems. However, as with any online marketplace, it has also become a breeding ground for scams.

Get ready for an unforgettable first encounter! This week on I Feel You, our regular NVee meets special DJ Xander—the ultimate non-kkondae idol sbn! From hilarious icebreakers to shared stories...

[more...]

Deflectometric profilometers are used to precisely measure the form of beam shaping optics of synchrotrons and X-ray free-electron lasers. They often utilize autocollimators which measure slope by evaluating the displacement of a reticle image on a detector. Based on our privileged access to the raw image data of an autocollimator, novel strategies to reduce the systematic measurement errors by using a set of overlapping images of the reticle obtained at different positions on the detector are discussed. It is demonstrated that imaging properties such as, for example, geometrical distortions and vignetting, can be extracted from this redundant set of images without recourse to external calibration facilities. This approach is based on the fact that the properties of the reticle itself do not change – all changes in the reticle image are due to the imaging process. Firstly, by combining interpolation and correlation, it is possible to determine the shift of a reticle image relative to a reference image with minimal error propagation. Secondly, the intensity of the reticle image is analysed as a function of its position on the CCD and a vignetting correction is calculated. Thirdly, the size of the reticle image is analysed as a function of its position and an imaging distortion correction is derived. It is demonstrated that, for different measurement ranges and aperture diameters of the autocollimator, reductions in the systematic errors of up to a factor of four to five can be achieved without recourse to external measurements.

The synthesis and structural characterization of four novel supra­molecular hy­dro­gen-bonded arrangements based on self-assembly from mol­ecular `[Cu(2,2'-bi­imid­az­ole)]' modules and malonate anions are pre­sent­ed, namely, tetra­kis­(2,2'-bi­imid­az­ole)di-μ-chlorido-dimal­on­atotricopper(II) penta­hydrate, [Cu3(C3H2O4)2Cl2(C6H6N4)4]·5H2O or [Cu(H2biim)2(μ-Cl)Cu0.5(mal)]2·5H2O, aqua­(2,2'-bi­imid­az­ole)­mal­on­atocopper(II) dihydrate, [Cu(C3H2O4)(C6H6N4)(H2O)]·2H2O or [Cu(H2biim)(mal)(H2O)]·2H2O, bis­[aqua­bis­(2,2'-bi­imid­az­ole)­cop­per(II)] di­mal­on­atodi­perchloratocopper(II) 2.2-hydrate, [Cu(C6H6N4)2(H2O)]2[Cu(C3H2O4)(ClO4)2]·2.2H2O or [Cu(H2biim)2(H2O)]2[Cu(mal)2(ClO4)2]·2.2H2O, and bis­(2,2'-bi­imid­az­ole)­copper(II) bis­[bis­(2,2'-bi­imid­az­ole)(2-carb­oxy­acetato)mal­on­atocopper(II)] tridecahydrate, [Cu(C6H6N4)2][Cu(C3H2O4)(C3H3O4)(C6H6N4)2]·13H2O or [Cu(H2biim)2][Cu(H2biim)2(Hmal)(mal)]2·13H2O. These as­sem­blies are characterized by self-com­plementary donor–acceptor mol­ecular inter­actions, demonstrating a recurrent and distinctive pattern of hy­dro­gen-bonding preferences among the carboxyl­ate, carb­oxy­lic acid and N—H groups of the coordinated 2,2'-bi­imid­az­ole and malonate ligands. Additionally, co­or­din­ation of the carboxyl­ate group with the metallic centre helps sustain re­mark­able supra­molecular assemblies, such as layers, helices, double helix columns or 3D channeled architectures, including mixed-metal com­plexes, into a single structure.

Spectroscopic data, particularly diffraction data, are essential for materials characterization due to their comprehensive crystallographic information. The current crystallographic phase identification, however, is very time consuming. To address this challenge, we have developed a real-time crystallographic phase identifier based on a convolutional self-attention neural network (CPICANN). Trained on 692 190 simulated powder X-ray diffraction (XRD) patterns from 23 073 distinct inorganic crystallographic information files, CPICANN demonstrates superior phase-identification power. Single-phase identification on simulated XRD patterns yields 98.5 and 87.5% accuracies with and without elemental information, respectively, outperforming JADE software (68.2 and 38.7%, respectively). Bi-phase identification on simulated XRD patterns achieves 84.2 and 51.5% accuracies, respectively. In experimental settings, CPICANN achieves an 80% identification accuracy, surpassing JADE software (61%). Integration of CPICANN into XRD refinement software will significantly advance the cutting-edge technology in XRD materials characterization.

Cryogenic electron microscopy (cryo-EM) is a pivotal technique for imaging macromolecular structures. However, despite extensive processing of large image sets collected in cryo-EM experiments to amplify the signal-to-noise ratio, the reconstructed 3D protein-density maps are often limited in quality due to residual noise, which in turn affects the accuracy of the macromolecular representation. Here, crefDenoiser is introduced, a denoising neural network model designed to enhance the signal in 3D cryo-EM maps produced with standard processing pipelines. The crefDenoiser model is trained without the need for `clean' ground-truth target maps. Instead, a custom dataset is employed, composed of real noisy protein half-maps sourced from the Electron Microscopy Data Bank repository. Competing with the current state-of-the-art, crefDenoiser is designed to optimize for the theoretical noise-free map during self-supervised training. We demonstrate that our model successfully amplifies the signal across a wide variety of protein maps, outperforming a classic map denoiser and following a network-based sharpening model. Without biasing the map, the proposed denoising method leads to improved visibility of protein structural features, including protein domains, secondary structure elements and modest high-resolution feature restoration.

Neutron spectroscopy uniquely and non-destructively accesses diffusive dynamics in soft and biological matter, including for instance proteins in hydrated powders or in solution, and more generally dynamic properties of condensed matter on the molecular level. Given the limited neutron flux resulting in long counting times, it is important to optimize data acquisition for the specific question, in particular for time-resolved (kinetic) studies. The required acquisition time was recently significantly reduced by measurements of discrete energy transfers rather than quasi-continuous neutron scattering spectra on neutron backscattering spectrometers. Besides this reduction in acquisition times, smaller amounts of samples can be measured with better statistics, and most importantly, kinetically changing samples, such as aggregating or crystallizing samples, can be followed. However, given the small number of discrete energy transfers probed in this mode, established analysis frameworks for full spectra can break down. Presented here are new approaches to analyze measurements of diffusive dynamics recorded within fixed windows in energy transfer, and these are compared with the analysis of full spectra. The new approaches are tested by both modeled scattering functions and a comparative analysis of fixed energy window data and full spectra on well understood reference samples. This new approach can be employed successfully for kinetic studies of the dynamics focusing on the short-time apparent center-of-mass diffusion.

Young athletes in the U.S. face a culture of resistance to reporting when they might have a concussion and to complying with treatment plans.

The National Academy of Sciences is presenting its 2015 Public Welfare Medal to astrophysicist, cosmologist, author, and science communicator Neil deGrasse Tyson

The National Academy of Sciences is presenting its 2018 Public Welfare Medal to physician, anthropologist, and humanitarian Paul Farmer.

Rev. Heber Brown III wants people to erase the term “food desert” from their vocabulary.

Scientists at Iowa State University have developed a new formulation that helps to explain the self-assembly of atoms into nanoclusters and to advance the scientific understanding of related nanotechnologies. Their research offers a theoretical framework to explain the relationship between the distribution of "capture zones," the regions that surround the nanoscale "islands" formed by deposition on surfaces, and the underlying nucleation or formation process.

read more

Auto Contact, our range of self-service solutions, can help free up agents to handle more complex and revenue-generating calls –and at the same time improve the overall customer experience whilst reducing costs.

Amazon's shares were 1.2% higher at $128.84 in early afternoon trading.

The natural frozen bread brand expands into shelf-stable with three new nutrient-dense and fiber-rich clean bread varieties.

Ernie and the Elves are bringing magic to holiday traditions with the launch of Elf Limited-Edition Keebler Gingerbread Fudge Stripes and new Keebler Pretzel Pie Crusts.

Advances in packaging materials continue to extend shelf life, while adding convenience and freshness to bakery and snack goods. Innovations in modified-atmosphere packaging (MAP), microbial-inhibiting film, and the use of cellulose nanocrystals are helping to push the envelope.

Chips Ahoy! is bringing back a flavor for the first time in 8+ years: Chips Ahoy! Hot Cocoa.