The rainbow sports bra and leggings set from Splits59 is a must-have for anyone craving a pop of color in their workout wardrobe.

Italian translation of the BIS press release about the BIS Quarterly Review, September 2017

Italian translation of the BIS Quarterly Review, September 2017

Italian translation of the BIS Quarterly Review, September 2018

Italian version of BIS Press Release - Big tech in finance: opportunities and risks, 23 June 2019

Giving birth triggers a wide repertoire of physiological and behavioral changes in the mother to enable her to feed and care for her offspring. These changes require coordination and are often orchestrated from the CNS, through as of yet poorly understood mechanisms. A neuronal population with a central role in puerperal changes is the tuberoinfundibular dopamine (TIDA) neurons that control release of the pituitary hormone, prolactin, which triggers key maternal adaptations, including lactation and maternal care. Here, we used Ca²⁺ imaging on mice from both sexes and whole-cell recordings on female mouse TIDA neurons in vitro to examine whether they adapt their cellular and network activity according to reproductive state. In the high-prolactin state of lactation, TIDA neurons shift to faster membrane potential oscillations, a reconfiguration that reverses upon weaning. During the estrous cycle, however, which includes a brief, but pronounced, prolactin peak, oscillation frequency remains stable. An increase in the hyperpolarization-activated mixed cation current, I_h, possibly through unmasking as dopamine release drops during nursing, may partially explain the reconfiguration of TIDA rhythms. These findings identify a reversible plasticity in hypothalamic network activity that can serve to adapt the dam for motherhood.

SIGNIFICANCE STATEMENT Motherhood requires profound behavioral and physiological adaptations to enable caring for offspring, but the underlying CNS changes are poorly understood. Here, we show that, during lactation, neuroendocrine dopamine neurons, the "TIDA" cells that control prolactin secretion, reorganize their trademark oscillations to discharge in faster frequencies. Unlike previous studies, which typically have focused on structural and transcriptional changes during pregnancy and lactation, we demonstrate a functional switch in activity and one that, distinct from previously described puerperal modifications, reverses fully on weaning. We further provide evidence that a specific conductance (I_h) contributes to the altered network rhythm. These findings identify a new facet of maternal brain plasticity at the level of membrane properties and consequent ensemble activity.

International Kungfu superstar and renowned Hollywood film actor Jackie Chan has joined FAO in the fight against hunger. In a recent visit to Ethiopia, Chan met with beneficiaries of the ‘Purchase from Africans for Africa’ (PAA) project as well as a South-South Cooperation Programme where he discussed with Chinese experts how they exchange technical knowledge with Ethiopian farmers to help them [...]

Autumn Ray's goal: 59 national parks before she turns 40 in four years

An abstract aerial view of a sand dune at sunset at Imperial Sand Dunes, Glamis, California.

A young white bear from Manitoba while lazily enjoying a soft snowfall. It is morning in Hudson Bay, Canada, and the bear has just woken up. I succeeded in capturing it at an extreme temperature (-26 °), in a surreal silence, after observing its habits for a few days. The polar bear spends most of its time sleeping and lounging in the snow. It only moves when it's hungry. To hunt its favorite prey - the seal - it is willing to walk hundreds of miles. Its refined nose allowes the bear to sneak up on its prey with a paw when the seal rises to the surface to breathe.

Sunset at Lake Wanaka

A Guanaco (Lama guanicoe) surveys its surroundings from a vantage point at sunset, with the imposing Torres del Paine (Chile) in the background. Scouts like this individual keep an eye out for predators.

A Stormy Sunset for Elephants

Magenta skies over Monument Valley at sunset.

Some New Brunswickers will be heading back to work next week, but their regular childcare facilities may not be available. 

A spring storm is set to slam parts of New Brunswick this weekend, bringing up to 30 cm of snow. 

RCMP say they were first called about the fires at 10 p.m. CST on May 7.

The RCMP say criminal charges are pending after a report came in about an arson Friday morning, in which everyone inside was able to escape with no injuries.

Service Team members share why they enjoy being onsite during Setup Week, when the vision of TeenStreet becomes a reality for them, and what part of the upcoming conference they are most excited for.

Press release: CPMI report sets out considerations for developers of wholesale digital tokens, 12 December 2019

Press release: Basel Committee invites comments on the design of a prudential treatment for crypto-assets, 12 December 2019.

BCBS Press release "Basel Committee sets out additional measures to alleviate the impact of Covid-19", 3 April 2020

Press release "Saudi G20 Presidency and the Bank for International Settlements (BIS) Innovation Hub invite global innovators to solve RegTech and SupTech challenges", 27 April 2020

When the province eventually conducts its review on the response to COVID-19, the president of the Nova Scotia Nurses’ Union can think of one thing in particular that needs to be discussed.

Inflation pressure could be weak even after consumer demand for non-discretionary goods and services begins to grow as the economy gets back on its feet.

Grit and red wine: Famous war photographer beats virus at 97  WSET

Pence says lack of religious services has been 'burden'  WSET

The 2020 NFL Draft was the most watched ever, with more than 55 million U.S. viewers tuning in during the unique three-day event.

Farmers markets throughout B.C.’s Interior and South Coast are ramping up for their spring seasons, but COVID-19 has forced them to make some changes to how they operate. 

Three people living in the mountains of Western Canada tell us about the beauty, the lifestyle and the danger of calling them home.

Inflation pressure could be weak even after consumer demand for non-discretionary goods and services begins to grow as the economy gets back on its feet.

While Apple has not revealed any viewing figures for Apple TV+, industry sources say the new "Defending Jacob" drama is a hit with higher viewing figures, and audience engagement, than most shows on the service.

When you're having connection problems, or if you find that they are not charging correctly, you may need to reset your AirPods or AirPods Pro. Here's how to get it done.

Being able to have an overview of changes to designs since initial release is an important aspect to time-efficient engineering. Making use of an automatically updated revision table helps with that.  What version are we using? Who has made these

Author information

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While enjoying the sunset on the beach in Israel, an OM worker has an opportunity to share her faith.

OMer MacDonald shares how a church in rural Malawi started and has started reaching out.

Veracruz, Mexico :: The Ship Ministry receives the largest number of visitors in a single port, breaking a 30-year record.

BACKGROUND AND OBJECTIVES:

Children with autism spectrum disorder (ASD) have a higher prevalence of epilepsy compared with general populations. In this pilot study, we prospectively identified baseline risk factors for the development of seizures in individuals with ASD and also identified characteristics sensitive to seizure onset up to 6 years after enrollment in the Autism Speaks Autism Treatment Network.

OBJECTIVES:

To determine if a multicomponent intervention was associated with increased use of first-line antibiotics (cephalexin or sulfamethoxazole and trimethoprim) among children with uncomplicated urinary tract infections (UTIs) in outpatient settings.

A Fin24 user asks whether saving is better when debt is paid off or not.

Against the backdrop of the global corona crisis and a collapse in flight operations, the Supervisory Board today set the important course for the development of the airport company after commissioning BER.

Millie Small, who died Tuesday at age 73 in London, was the first Jamaican artiste to score a hit on the British pop chart. Her version of My Boy Lollipop reached number two in 1964 and was also successful in the United States, Ireland, Canada, Australia, and New Zealand.

SCOTLAND'S capital is coming to terms with the "heart-breaking" news that its summer festivals will not go ahead this year - costing the city hundreds of millions of pounds.

GUTTING news for great swathes of the Great British public - eating chips is not exercise.

Scotland needs to plant up to one billion trees to achieve the country’s ambitious climate change goals and help the economy recover from the coronavirus crisis, a group of environmental consultants have said.