si Dual-functional porphyrinic zirconium-based metal–organic framework for the fluorescent sensing of histidine enantiomers and Hg2+ By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2386-2399DOI: 10.1039/D3AY02241B, PaperShili Qin, Fanshu Meng, Fenglong Jin, Xidi Xu, Ming Zhao, Hongtao Chu, Lidi Gao, Shuren LiuL-Cys/PCN-222 as a novel and dual-functional fluorescent sensor was developed. It not only showed a higher chiral fluorescent recognition of L-histidine but also performed as a visual sensor for Hg2+ in actual surface water.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Anti-aggregation colorimetric sensing of cysteine using silver nanoparticles in the presence of Pb2+ By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2378-2385DOI: 10.1039/D4AY00351A, PaperLihui Mao, Yi Zhang, Huan Zhang, Huili Liu, Yong-ping GaoIn this study, an unmodified AgNPs was synthesized to prepare AgNPs-Pb2+ as a probe for colorimetric sensing of cysteine. We developed a AgNPs colorimetric method for the determination of cysteine in urine, utilizing the anti-aggregation principle.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si A chemiluminescence immunoassay for type IV collagen as a promising marker for liver fibrosis and cirrhosis By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2248-2255DOI: 10.1039/D3AY02240D, PaperXiaoling Fu, Fan Zhang, Fangda Zhen, Lian Duan, Jian Zhou, Jianguo MaHerein, a magnetic bead-based chemiluminescence assay is reported to detect type IV collagen (col-IV) in serum samples.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Analysing micro- and nanoplastics with cutting-edge infrared spectroscopy techniques: a critical review By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2177-2197DOI: 10.1039/D3AY01808C, Critical Review Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Junhao Xie, Aoife Gowen, Wei Xu, Junli XuIn this review, we discussed and compared the applications of Fourier transform infrared spectroscopy, quantum cascade laser infrared spectroscopy, atomic force microscopy-based infrared spectroscopy, and optical photothermal infrared spectroscopy in MNP research from multiple perspectives.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si A new colorimetric aptasensor for paraquat detection based on the designed aptamer with multiple paraquat binding sites in combination with gold nanoparticles By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2340-2348DOI: 10.1039/D4AY00053F, PaperPakawat Kongpreecha, Sineenat SiriGiven paraquat's environmental health risks, there is a need for a fast and simple detection method. This study presents a novel colorimetric aptasensor with a tailored aptamer, boosting sensitivity by targeting multiple paraquat binding sites.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si An immunochromatographic strip sensor for rapid and sensitive detection of candesartan, olmesartan medoxomil, and irbesartan in herbal beverages By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2359-2367DOI: 10.1039/D4AY00151F, PaperDingyu Li, Aihong Wu, Liqiang Liu, Hua Kuang, Chuanlai Xu, Xiaoling WuSartans, as a class of antihypertensive drugs, pose a threat to human health when illegally added to herbal beverages.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si A novel electrophoretic assisted hydrophobic microdevice for enhancing blood cell sorting: design and numerical simulation By pubs.rsc.org Published On :: Anal. Methods, 2024, 16,2368-2377DOI: 10.1039/D4AY00196F, PaperXinkun Chen, Xueye ChenMicrofluidic technology has great advantages in the precise manipulation of micro–nano particles, and the hybrid microfluidic separation technology has attracted much attention due to the advantages of both active and passive separation technology at the same time.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00146J, PaperDumei Ma, Yiting Luo, Xiaoya Zhang, Zehu Xie, Yinghua Yan, Chuan-Fan DingA fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Analysis of brominide disinfection by-products in aquaculture water using ultra-high-performance liquid chromatography–quadrupole–time-of-flight mass spectrometry By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00396A, PaperWeimin Yang, Yi Zhang, Jilong Huang, Xing Yang, Ning JiangBackground: Halogenic disinfectants have been shown to produce toxic and carcinogenic disinfection by-products (DBPs) during water disinfection. Dibromohydantoin (DBDMH) is a commonly used water disinfectant in aquaculture. Aquaculture water has...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Detection of Free DNA Based on Metal-Enhanced Fluorescence Triggered by CRISPR-Cas12a and Colorimetric Analysis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00149D, PaperMing-Qiu Zheng, Yuyao Li, Liling Zhang, Cheng-Yu Li, Menghan Liu, Hongwu TangThe CRISPR-Cas system has been found to be extremely sensitive and there is an urgent demand to extend its potential in bioassay. Herein, we developed a novel nanobiosensor to detect...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si A simple and rapid colorimetric detection of Staphylococcus Aureus relied on the distance-dependent optical properties of silver nanoparticles By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D3AY02189K, PaperNgoc Anh Thu Phan, Hoang Men Nguyen, Cam Duyen Thi Vo, Toi Vo Van, Phuoc Long TruongThe quick and accurate diagnosis of pathogens has appeared as a pressing issue in clinical diagnostics, environmental monitoring, and food safety. The current assays are suffering from limited capacities in...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Simple fluorescence “turn-off” assay for Congo red using commercial 2-aminophthalic acid By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00506F, PaperJiaqi Qian, Jie Li, Yihan Jiang, Chaoyong Liu, Jiayao Zhu, Liyu Gu, Yongming Guo2-Aminophthalic acid with a high quantum yield of 38.49% was utilized for fluorescence “turn-off” sensing of Congo red with a linear range of 0.05–50 μM and a limit of detection of 1.72 μM.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Electroanalysis overview: additive manufactured biosensors using fused filament fabrication By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00278D, Minireview Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Robert D. Crapnell, Craig E. BanksAdditive manufacturing (3D-printing), in particular fused filament fabrication, presents a paradigm shift in the way electrochemical based biosensing platforms are produced, giving rise to a new generation of personalized and on-demand biosensors.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Quantifying platinum binding on protein-functionalized magnetic microparticles using single particle-ICP-TOF-MS By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00268G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Veronica C. Bradley, Benjamin T. Manard, Lyndsey Hendriks, Daniel R. Dunlap, Amber N. Bible, Ada Sedova, Patricia Saint-Vincent, Brian C. Sanders, Hunter B. AndrewsThis work describes an analytical procedure, single particle-inductively coupled plasma-time-of-flight-mass spectrometry (SP-ICP-TOF-MS), that was developed to determine the platinum binding efficiency of protein-coated magnetic microparticles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00487F, PaperJinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang LiuSmall extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Design and fabrication of La-based perovskites incorporated with functionalized carbon nanofibers for the electrochemical detection of roxarsone in water and food samples By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00264D, PaperMariya Antony John Felix, Santhiyagu Sahayaraj Rex Shanlee, Shen-Ming Chen, Sundaresan Ruspika, Ramachandran Balaji, Narendhar Chandrasekar, Periyanayagam Arockia DossFabrication of potent electrocatalyst, La-based perovskites coupled with functionalized carbon nanofibers (LMO/f-CNF) for ultrasensitive electrochemical detection of roxarsone in edible and water samples.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si The preparation of a boronate affinity-based controlled oriented imprinting coating on a silica nanoparticle surface for the separation and purification of shikimic acid in herbal medicine By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00219A, PaperYumin Yang, Daojin Li, Bingqian LiuShikimic acid (SA) is one of the most effective drugs against the A (H1N1) virus and has high medicinal value.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Α simplified lateral flow immunosensor for the assay of carcinoembryonic antigen in low-resource settings By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00381K, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ioanna Tsogka, Electra Mermiga, Varvara Pagkali, Christos Kokkinos, Anastasios EconomouCarcinoembryonic antigen (CEA) is a glycoprotein widely used as a tumor marker. In this work, a colorimetric lateral flow immunosensor is developed for rapid and low-cost quantification of CEA in...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si A chemodosimetric chemosensor for the ratiometric detection of nerve agent-mimic DCP in solution and vapor phases By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00451E, PaperShilpita Banerjee, Pintu Ghosh, Anirban Karak, Dipanjan Banik, Ajit Kumar MahapatraThe probe MNFZ undergoes a hydrolysis reaction in the presence of DCP to exhibit a naked eye color change from blue to cyan. It was successfully applied to sense DCP in the vapor phase.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Novel advanced materials and magnetic solid phase extraction as approaches in sample preparation to enhance the analysis of ochratoxin A in peanuts By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00246F, PaperBingchen Wang, Yifan Wang, Xiuyuan Zhang, Kuo HeIn order to improve the detection efficiency of ochratoxin, a superparamagnetic nano-material was synthesized for solid phase extraction of ochratoxin.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Three-dimensional hotspot structures constructed from nanoporous gold with a V-cavity and gold nanoparticles for surface-enhanced Raman scattering By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00348A, PaperYang Xu, Yan Wu, Jianjun Wei, Yuanyu Zhao, Peili XueA nanoporous gold V-shaped resonant cavity (NPGVRC) structure constructed with plasmonic resonance coupling effect. The NPGVRC has excellent SERS performance and 3D hotspot properties.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si A colorimetric tandem combination of CRISPR/Cas12a with dual functional hybridization chain reaction for ultra-sensitive detection of mycobacterium bovis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D3AY02200E, PaperQiong Liu, Mei Yang, He Zhang, Wenjie Ma, Xin Fu, Huiqing Li, Sainan GaoTuberculosis caused by Mycobacterium bovis poses a global infectious threat to humans and animals. Therefore, there is an urgent need to develop a sensitive, precise, and easy-to-readout strategy. Here, a...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Losing a friend, virtually By www.thehindubusinessline.com Published On :: Mon, 03 Jun 2013 13:04:35 +0530 Full Article R Dinakaran
si Missing the obvious By www.thehindubusinessline.com Published On :: Mon, 29 Jul 2013 17:04:17 +0530 Full Article R Dinakaran
si Weather gods: On ‘Mission Mausam’ By www.thehindu.com Published On :: Sat, 14 Sep 2024 00:10:00 +0530 Attempts at controlling the weather are still in the realm of uncertainty Full Article Editorial
si Unrealistic expectations: On India and Russia-Ukraine peace By www.thehindu.com Published On :: Mon, 16 Sep 2024 00:37:00 +0530 India’s efforts at peacemaking between Russia and Ukraine have limited potential Full Article Editorial
si Clarity of vision: On eye drops for presbyopia and ‘claims’ By www.thehindu.com Published On :: Tue, 17 Sep 2024 00:15:00 +0530 A useful drug is undone by fantastic claims about its efficacy Full Article Editorial
si Down to the wire: On the run-up to the U.S. presidential election By www.thehindu.com Published On :: Tue, 17 Sep 2024 00:30:00 +0530 The U.S. presidential race is poised on a knife’s edge Full Article Editorial
si Third front: On the expanding nature of the conflict in West Asia By www.thehindu.com Published On :: Wed, 18 Sep 2024 00:10:00 +0530 Israel’s fighting three enemy militias at once highlights the pressing need for a ceasefire Full Article Editorial
si Wrong notion: On simultaneous elections By www.thehindu.com Published On :: Fri, 20 Sep 2024 00:10:00 +0530 The idea of simultaneous elections is inherently anti-federal Full Article Editorial
si Sri Lanka’s verdict: On the Island nation’s ninth Presidential election By www.thehindu.com Published On :: Mon, 23 Sep 2024 00:10:00 +0530 The spirit of the mandate of the presidential poll was clear — for change Full Article Editorial
si Politicising the laddu: On the Tirupati laddu and its ‘adulteration’ By www.thehindu.com Published On :: Tue, 24 Sep 2024 00:30:00 +0530 The Tirupati laddu issue should be limited to one of quality control Full Article Editorial
si Visit wrap-up: On PM Modi’s U.S. visit, announcements By www.thehindu.com Published On :: Wed, 25 Sep 2024 00:20:00 +0530 The Modi U.S. visit announcements will see New Delhi being put to the test Full Article Editorial
si Embattled CM: On Karnataka Chief Minister Siddaramaiah By www.thehindu.com Published On :: Fri, 27 Sep 2024 00:20:00 +0530 Anti-graft moves should not be overshadowed by political motive Full Article Editorial
si Mad doctrine: On Russia’s revision of its nuclear doctrine By www.thehindu.com Published On :: Mon, 30 Sep 2024 00:10:00 +0530 Any threat of use of nuclear weapons must be viewed seriously Full Article Editorial
si Steady but slow: On the VIPER mission, lessons for India By www.thehindu.com Published On :: Tue, 01 Oct 2024 00:30:00 +0530 India’s space programme needs more resources to realise its full potential Full Article Editorial
si The edge of war: On the West Asia situation By www.thehindu.com Published On :: Tue, 01 Oct 2024 00:57:00 +0530 Iran should not give Israel an excuse to widen the war Full Article Editorial
si Healthy sign: On the voting in the 2024 J&K Assembly elections By www.thehindu.com Published On :: Thu, 03 Oct 2024 00:10:00 +0530 Turnout numbers in the Assembly elections show distinct patterns in south Kashmir Full Article Editorial
si Inflection point: On the escalation in the multi-party West Asia conflict By www.thehindu.com Published On :: Thu, 03 Oct 2024 00:20:00 +0530 West Asia needs the intervention of major world powers for peace Full Article Editorial
si Split decision: On the rivalry between the two NCP factions By www.thehindu.com Published On :: Fri, 04 Oct 2024 00:25:00 +0530 The ECI and the office of the Speaker have not played fair in cases of defection Full Article Editorial
si Deep roots: On the 2024 Physics Nobel Prize By www.thehindu.com Published On :: Wed, 09 Oct 2024 00:10:00 +0530 Physics Nobel Prize acknowledges the diverse foundations of AI Full Article Editorial
si Deeper role: On the U.S. and West Asia conflicts By www.thehindu.com Published On :: Wed, 16 Oct 2024 00:10:00 +0530 The escalating conflict cycle in West Asia could have disastrous consequences Full Article Editorial
si Neck and neck: On the U.S. presidential election By www.thehindu.com Published On :: Sat, 26 Oct 2024 00:10:00 +0530 Trump and Harris offer U.S. voters vastly different choices Full Article Editorial
si Sun signs: On extreme heat and Tamil Nadu’s policy decision By www.thehindu.com Published On :: Thu, 31 Oct 2024 00:10:00 +0530 States should prepare to assist the vulnerable during extreme heat events Full Article Editorial
si Towards Europe: On the India visits by the leaders of Germany, Spain By www.thehindu.com Published On :: Thu, 31 Oct 2024 00:20:00 +0530 India used visits by leaders of Germany and Spain to balance ties in Europe Full Article Editorial
si Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00660G, Review ArticleShutang Li, Jinfei YangAs research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Design, synthesis, inhibitory activity, and molecular simulations study for D-glucose-conjugated thioureas containing pyrimidine ring as multitarget inhibitors against α-amylase, α-glucosidase, DDP-4, and PTP1B in Type 2 diabetes mellitus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3395-3417DOI: 10.1039/D4MD00334A, Research ArticleVu Ngoc Toan, Do Son Hai, Hoang Thi Kim Van, Nguyen Minh Tri, Duong Ngoc Toan, Nguyen Thi Thanh Mai, Nguyen Dinh ThanhD-Glucose-conjugated thioureas from 2-aminopyrimidines had inhibitory activity against α-amylase, α-glucosidase, DPP-4, PTP1B. The cytotoxicity, inhibitory kinetics, and molecular simulations of the most potent inhibitors 8k, 8j, 8f, and 8h were studied.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si The role of silicon in drug discovery: a review By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3286-3344DOI: 10.1039/D4MD00169A, Review Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jenny-Lee Panayides, Darren Lyall Riley, Felix Hasenmaile, Willem A. L. van OtterloThis review aims to highlight the role of silicon in drug discovery.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si Integrating amino acids into Bcr-Abl inhibitors: design, synthesis, biological evaluation, and in silico studies By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3507-3528DOI: 10.1039/D4MD00417E, Research ArticleYuying Liu, Zeyu Yang, Jie Zhang, Na Guo, Nanxin Liu, Qingqing Zhang, Xintao Dang, Yanchen Li, Jie Zhang, Xiaoyan PanIn continuation of our previous research, a series of novel Bcr-AblT315I inhibitors with tert-leucine or serine as a flexible linker were developed and biological evaluation was performed in vitro.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
si The synthesis and bioactivities of ROCK2 inhibitors with 1,2-dithiolan-3-yl motif By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3576-3596DOI: 10.1039/D4MD00438H, Research ArticleRuolin Cao, Fangyu Du, Zhiqiang Liu, Pengcheng Cai, Minggang Qi, Wei Xiao, Xuefei Bao, Guoliang ChenRho-associated coiled-coil containing kinase (ROCK) plays an important role in inflammation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article