Ai-Da creates art using A.I. algorithms, cameras and robotic arms. Her abstract painting will be the first-ever artwork made by a humanoid robot to be sold at Sotheby's

A blockbuster exhibition in Paris is showcasing 500 artifacts and artworks in honor of the Surrealist Manifesto, which sparked a new artistic style that spread around the world

The owners inherited the valuable coin from their brother, who kept it locked in a bank vault for decades. He purchased it with his mother in 1978 to provide financial security for the family farm

After a summer that tied for the country's hottest, meteorologists say an unusually warm autumn is delaying snowfall

The public tours of the historic residence hadn't been overhauled in decades. For two years, the first lady's office has been working to make them more interactive and educational

A "staggering array" of markings have been hiding in plain sight carved into the walls of Gainsborough Old Hall, a 500-year-old home in Lincolnshire, England

The species may have been carried to the Sacramento–San Joaquin Delta in ballast water on ships

The pachyderm, named Kamala, was suffering from osteoarthritis when zoo staff chose to euthanize her

The votive plaque was found amid the ruins of an ancient Roman fortress. Researchers think a temple dedicated to the mysterious deity may have stood nearby

The Art Gallery of New South Wales is showcasing works full of the Surrealist artist's signature motifs—such as apples, pipes and bowler hats—in addition to lesser-known pieces

Thousands of years ago, our ancestors used symbols to track the sale of textile and agricultural products. New research suggests that these markings informed the development of writing

An exhibition in London is showcasing more than 600 artworks and artifacts—including costumes, props and sketches—from the famous filmmaker’s career

Antonia, a cloned black-footed ferret at the Smithsonian's National Zoo and Conservation Biology Institute, has produced two healthy offspring that will help build genetic diversity in their recovering population

Steve Lazarides' personal collection of prints, original works, handwritten press releases and burner phones sold at auction for around $1.4 million

On its 66th flyby of the king of planets, Juno has captured spectacular views of the stormy atmosphere, processed by citizen scientists

The viral king penguin chick at Sea Life Melbourne Aquarium is beginning to lose his youthful down, a process that will give him his distinctive and waterproof adult plumage

Found in a cremation cemetery in Belgium, the skeleton includes bones dating to the Neolithic period and a Roman-era skull, according to a new study

It takes two weeks to dress the venue (which is in a mall, remember) for the occasion each year

Lula the bear and Simba the lion have been evacuated to a wildlife shelter in Jordan

Some 250 volunteers transported more than 2,000 books

The actress becomes the first wheelchair user ever to take home the coveted prize at the 73rd annual award show

The Cuban-American actor and producer has stars on Hollywood’s Walk of Fame, but this new honor pays tribute to his start as a musician in South Florida

These shots from the Smithsonian Magazine Photo Contest show why it’s one of the most-visited nations on earth

The team traveled from New Zealand to Tonga along a humpback highway to collect environmental DNA and raise awareness of the plight of the marine mammals

Cenotes in the Yucatán Peninsula are time capsules preserving remnants of Maya culture and fossils of extinct megafauna

See photographs of the beautiful natural wonders from the Smithsonian Magazine Photo Contest

Iconic images of Dr. King from the Smithsonian collection

See images of the American flag captured by our readers.

The surge of hungry four-legged visitors to Belushya Guba is part of a larger trend

In summer months above the North and South Poles, glowing clouds occasionally form naturally at sunset under the right conditions

In a twist befitting its pages, the satirical, anti-establishment publication that delivered laughs and hijinks to generations of young readers gets the respect it always deserved with a new museum exhibition

A century on, the country’s most beloved Thursday spectacle reaches new heights

On the island of Laeso in Denmark, one man is reviving the lost art of eelgrass thatching and, in doing so, bringing attention to a plant that has great potential

Adverse weather has cancelled ferry crossings between Newfoundland and Labrador and Nova Scotia heading into the long weekend.

Shallaway Youth Choir is bringing a program of music to the Basilica in downtown St. John’s on Remembrance Day. Artistic director Kellie Walsh says the choir will sing about such topics as the Unknown Soldier and schoolchildren who care for Newfoundland graves in London. Where Once They Stood will be performed at 2 p.m. and 7 p.m. on Monday.

Newfoundland filmmaker Justin Simms is releasing his latest film called Sons. It was prompted by the birth of his son and left him wondering how traditional masculine behaviour is learned.

Police have reported that a man was fatally electrocuted in Torbay on Saturday evening. Two others are being treated for injuries.

Large crowds came together at city hall in Corner Brook to lay wreaths and honour veterans on Monday. The ceremony portion was completed with a playing of the Last Post.

After a year of negotiations, the postal union has given Canada Post a 72-hour strike notice. At a solidarity rally in St. John's last week, local president Craig Dyer says a strike could mean parcels — including Christmas presents — won't make it to rural communities.

CBC Newfoundland and Labrador would love to hear your suggestions of folks and organizations who are there when you need them — and all the other times, too.

People using the library in the Arts and Culture Centre in St. John's are being forced to use alternate entrances due to an unsafe staircase in front of the building.

A Port Hawkesbury woman has long imagined a Remembrance Day with her great-uncle's war medals. It will happen this year for the first time thanks to some sleuthing and the kindness of her great-uncle's foster family.

Kate MacEachern is a Canadian veteran from Ballantynes Cove, N.S., but her service years are far from over. She has spent about two years living in Ukraine, delivering humanitarian aid to communities across the country.

As Nova Scotia politicians make their fall election promises, Julie Leggett is urging them to commit to helping people on income assistance stay cool during heat waves.

Shilei Du, 36, was charged Monday morning with the premeditated murder of his partner, Guangmei Ye, whose body was found Sunday in a residence on Fontenelle Street in Candiac, Que.

The City of Montreal wants to sell more land to community organizations, housing co-ops and other groups to build off-market housing. 

Facing soaring food prices and an escalating housing crisis, Quebec student associations are urgently calling on the provincial government to fund internships required for post-secondary training.

The union representing dockworkers in Montreal says Canada's labour minister forcing its members back to work at ports in Montreal and Quebec City marks a "dark day for workers' rights."

Genetically encoded calcium indicators (GECIs) allow for the noninvasive evaluation of neuronal activity in vivo, and imaging GECIs in Drosophila has become commonplace for understanding neural functions and connectivity in this system. GECIs can also be used as read-outs for studying sleep in this model organism. Here, we describe a methodology for tracking the activity of neurons in the fly brain using a two-photon (2p) microscopy system. This method can be adapted to perform functional studies of neural activity in Drosophila under both spontaneous and evoked conditions, as well as during spontaneous or induced sleep. We first describe a tethering and surgical procedure that allows survival under the microscopy conditions required for long-term recordings. We then outline the steps and reagents required for optogenetic activation of sleep-promoting neurons while simultaneously recording neural activity from the fly brain. We also describe the procedure for recording from two different locations—namely, the top of the head (e.g., to record mushroom body calyx activity) or the back of the head (e.g., to record central complex activity). We also provide different strategies for recording from GECIs confined to the cell body versus the entire neuron. Finally, we describe the steps required for analyzing the multidimensional data that can be acquired. In all, this protocol shows how to perform calcium imaging experiments in tethered flies, with a focus on acquiring spontaneous and induced sleep data.

The insect eggshell is a multifunctional structure with several important roles, including generating an entry point for sperm via the micropyle before oviposition, serving as an oviposition substrate attachment surface, and functioning as a protective layer during embryo development. Eggshell proteins play major roles in eggshell tanning and hardening following oviposition and provide molecular cues that define dorsal–ventral axis formation. Precise eggshell formation during ovarian follicle maturation is critical for normal embryo development and the synthesis of a defective eggshell often gives rise to inviable embryos. Therefore, simple and accurate methods for identifying eggshell proteins will facilitate our understanding of the molecular pathways regulating eggshell formation and the mechanisms underlying normal embryo development. This protocol describes how to isolate and enrich eggshells from mature oocytes of Aedes aegypti mosquitoes and how to extract their eggshell proteins for liquid chromatography with tandem mass spectrometry (LC–MS/MS) proteomic analysis. Although this methodology was developed for studying mosquito eggshells, it may be applicable to eggs from a variety of insects. Mosquitoes are ideal model organisms for this study as their ovarian follicle development and eggshell formation are meticulously regulated by blood feeding and their follicles develop synchronously throughout oogenesis in a time-dependent manner.