b Co. Enters Quebec With Acquisition of Prospective Lithium Project By www.streetwisereports.com Published On :: Thu, 31 Oct 2024 00:00:00 PST Source: Streetwise Reports 10/31/2024 American Salars Lithium Inc. (USLI:CSE; USLIF:OTC; Z3P:FWB; A3E2NY:WKN) has signed a mineral claims purchase agreement with an arm's length vendor to acquire 100% of the Lac Simard South Project in Quebec. Find out why one analyst says the market for the important battery metal is due to wake up.American Salars Lithium Inc. (USLI:CSE; USLIF:OTC; Z3P:FWB; A3E2NY:WKN) announced it has signed a mineral claims purchase agreement with an arm's length vendor to acquire 100% of the Lac Simard South Project in Quebec. The more than 3,600-hectare project covers 64 claim blocks contiguous to projects owned by Sayona Mining Ltd. and Refined Metals Corp.'s Lac Simard property that sampled 2.1% lithium (4.52% lithium oxide or Li2O) and 5.88% tantalum oxide (Ta2O5), the company said. "This is the company's entry point into Quebec with the intention of building a strategic portfolio of hard rock lithium projects to complement our lithium brine assets," Director and Chief Executive Officer R. Nick Horsley said. "The company's long-term belief in a lithium price rebound is steadfast and now is the time to build a multi-jurisdictional lithium company." The Lac Simard South project is about 80 kilometers southwest of Sayona’s Authier lithium project and spans the townships of Beauneville, Clérion, Delbreuil, and ChabertIt, and is accessible by gravel road off Route 117 near the municipality of Cadillac, American Salars said. "The claims in the eastern sector are accessible by a network of logging roads; the southern and western sectors are accessible by boat or all-terrain vehicle and has very little overburden," the company said in a release. American Salars said it will begin planning for a work program to identify targets and test areas at the project, which is in an "active lithium exploration, production, and processing region of mining-friendly Quebec." Located nearby is Sayona's Abitibi Hub — made up of its North American, Authier, and Tansim lithium projects — which boasts a "staggering aggregate measured and indicated resource of 111 million tonnes grading 1.14% lithium, the largest lithium resource in Quebec," American Salars said. The company also noted the lithium hub's accessibility provides relatively lower exploration costs than James Bay, and the area has a fully operating lithium concentrator and a planned lithium carbonate/hydroxide conversion plant. Additional Projects Being Reviewed, Co. Says Under the agreement, American Salars is acquiring a 100% interest in the Lac Simard South project by issuing 50,000 common shares to the vendor, Quartier Mineral Ltd of Quebec. The company said additional lithium projects are still being reviewed and will be subject to further disclosure once due diligence is completed and any deals are completed. "Our primary objective remains the acquisition of low-cost lithium brine assets in Argentina while expanding our existing NI 43-101 lithium brine resources," Horsley has said. "We believe that Quebec-based hard rock lithium assets can now be acquired at deeply discounted prices and advanced with critical mineral flow through financing incentives in anticipation of the next lithium rally." Technical Analyst Clive Maund wrote that the entire "San Emidio Desert basin is a highly prospective lithium exploration zone." The company's existing portfolio of lithium deposits includes two NI 43-101-compliant Inferred Mineral Resource Estimates (MREs) consisting of 457,000 tonnes of lithium carbonate equivalent (LCE) at the Candela 2 Lithium Brine Project and a shared MRE at the Pocitos 1 Lithium Brine Project consisting of 760,000 tonnes LCE. The Pocitos MRE is shared with the neighboring Pocitos 2 property, which is not under contract or owned by American Salars, but the company noted that none of the drilling that makes up a partial basis for the MRE took place on the Pocitos 2 block. Both brine projects are located in Salta Province, Argentina. Major mining company Rio Tino recently invested in Argentina by acquiring Argentina lithium producer Arcadium Lithium for US$6.7 billion, making the company the world's third-largest lithium producer. American Salars also recently released assay results from soil samples collected during its Phase 1 exploration program at its 100%-owned Black Rock South lithium project close to Tesla's Gigafactory in Nevada. Out of 38 samples, 33 recorded lithium concentration of more than 100 parts per million (ppm) or higher, the company said. The highest grade was 180.5 ppm with an average grade of 131 ppm across the 33 samples of the surface of the property. 'Basing Process' Underway for Commodity Technical Analyst Clive Maund wrote that the entire "San Emidio Desert basin is a highly prospective lithium exploration zone."* "After a massive speculative runup in 2020 and especially in 2021, the lithium price fell victim to a severe bear market that ran from mid-2022 through the end of 2023," Maund wrote. "By the end of last year, this bear market had exhausted itself, and a basing process began that has continued up to the present." Black Rock South is also 215 miles northwest of the United States' only producing lithium mine, the Silver Peak lithium brine mine owned by Albermarle. The Catalyst: Experts Predict Recovery Lithium is critical in the energy transition for its use in batteries for electric vehicles (EVs) and other application and is also used in electronics, medicine, and other industries. While prices have slumped this year after EV sales didn't hit predicted marks, many experts believe the market will recover. According to a report by Grand View Research, market size for the metal was estimated at US$31.75 billion last year and is projected to grow at a compound annual growth rate (CAGR) of 17.7% from this year through 2030. "The automotive application segment is expected to witness substantial growth, driven by stringent regulations imposed by government bodies on ICE automakers to reduce carbon dioxide emissions from vehicles," researchers at Grand View said. "This has shifted the interest of automakers toward producing EVs, which is anticipated to benefit the demand for lithium and related products." EVs and battery storage primarily will fuel future growth of the lithium market, Marin Katusa of Katusa Research wrote recently. He pointed out that all major electric vehicle batteries require lithium, about 1.55 pounds per kilowatt hour of battery capacity, on average.[OWNERSHIP_CHART-11095] "I think the data speaks for itself that there's more growth and opportunity on the horizon," Katusa wrote. The consensus among market analysts points to a recovery in lithium prices in the fourth quarter of 2024, Fastmarkets reported. Ownership and Share Structure American Salars said it has 28.8 million shares outstanding and 5.5 million warrants, according to the company. As for insiders, the CEO Horsley owns about 1.83 million, or about 7.37%, with 4666,666 warrants. Strategic investor Hillcrest Merchant Partners owns 1 million shares or 4.03%. There are no institutional investors, and the rest is retail. Its market cap is CA$4.79 million. It trades in a 52-week range of CA$0.45 and CA$0.08. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures: American Salars Lithium Inc.has a consulting relationship with Street Smart an affiliate of Streetwise Reports. Street Smart Clients pay a monthly consulting fee between US$8,000 and US$20,000. As of the date of this article, officers and/or employees of Streetwise Reports LLC (including members of their household) own securities of American Salars Lithium Inc. Steve Sobek wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an employee. This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. For additional disclosures, please click here. * Disclosure for the quote from the Clive Maund source June 17, 2024 For the quote (sourced on June 17, 2024), the Company has paid Street Smart, an affiliate of Streetwise Reports, US$1,500. Author Certification and Compensation: [Clive Maund of clivemaund.com] is being compensated as an independent contractor by Street Smart, an affiliate of Streetwise Reports, for writing the article quoted. Maund received his UK Technical Analysts’ Diploma in 1989. The recommendations and opinions expressed in the article accurately reflect the personal, independent, and objective views of the author regarding any and all of the designated securities discussed. No part of the compensation received by the author was, is, or will be directly or indirectly related to the specific recommendations or views expressed. Clivemaund.com Disclosures The quoted article represents the opinion and analysis of Mr. Maund, based on data available to him, at the time of writing. Mr. Maund's opinions are his own, and are not a recommendation or an offer to buy or sell securities. As trading and investing in any financial markets may involve serious risk of loss, Mr. Maund recommends that you consult with a qualified investment advisor, one licensed by appropriate regulatory agencies in your legal jurisdiction and do your own due diligence and research when making any kind of a transaction with financial ramifications. Although a qualified and experienced stock market analyst, Clive Maund is not a Registered Securities Advisor. Therefore Mr. Maund's opinions on the market and stocks cannot be only be construed as a recommendation or solicitation to buy and sell securities. ( Companies Mentioned: USLI:CSE; USLIF:OTC; Z3P:FWB; A3E2NY:WKN, ) Full Article
b Roth MKM Maintains Buy Rating on Energy Co. Following Insider Purchase By www.streetwisereports.com Published On :: Fri, 01 Nov 2024 00:00:00 PST Source: Leo Mariani 11/01/2024 "We rate Matador Resources Co. (MTDR:NYSE) a Buy based on the company's best-in-class production growth, strong inventory of wells, growing base dividend, and reasonable balance sheet," wrote Roth MKM analyst Leo Mariani.Roth MKM analyst Leo Mariani, in a research report published on November 1, 2024, maintained a Buy rating on Matador Resources Co. (MTDR:NYSE) with a price target of US$68.00. The report follows the announcement that MTDR's EVP of Production Glenn Stetson purchased company shares in the open market. Mariani highlighted the insider purchase, stating, "MTDR reported that EVP of Production Glenn Stetson bought 1,000 MTDR shares in the open market on October 30 for total proceeds of US$51,330 at an average price of US$51.33, which was 1.5% below yesterday's closing price of US$52.11." The analyst explained his positive view on the company, noting, "We rate Matador Resources Co. (MTDR) a Buy based on the company's best-in-class production growth, strong inventory of wells, growing base dividend, and reasonable balance sheet." Regarding Matador's operations, Mariani noted that the company has "192,000 net Permian acres, and most of its position is in the heart of the Delaware Basin. Its production mix is roughly 59% oil and 41% natural gas/NGLs." He also highlighted the company's midstream presence through its "51% ownership in San Mateo Midstream, which owns oil, gas, and water-gathering assets that are tied into MTDR's producing assets." Roth MKM's valuation methodology is based on a multiple of Debt-Adjusted Cash Flow (DACF). Mariani explained, "Our US$68 price target for MTDR is based on a 4.2x multiple of our 2025 DACF estimate, which is based on US$70 WTI oil and US$3.10 HH gas." The analyst also outlined several risk factors, including "slightly higher leverage than peers, completely unhedged in 2024; and acquisition risk given the company's propensity to do bolt-on M&A." In conclusion, Roth MKM's maintenance of a Buy rating and US$68 price target reflects confidence in Matador Resources' operational excellence and growth potential in the Permian Basin. The share price at the time of the report of US$52.11 represents a potential return of approximately 30.5% to the analyst's target price, suggesting significant upside potential as the company continues to execute its development strategy. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures: This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. For additional disclosures, please click here. Disclosures for Roth MKM, Matador Resources Co., November 1, 2024 Regulation Analyst Certification ("Reg AC"): The research analyst primarily responsible for the content of this report certifies the following under Reg AC: I hereby certify that all views expressed in this report accurately reflect my personal views about the subject company or companies and its or their securities. I also certify that no part of my compensation was, is or will be, directly or indirectly, related to the specific recommendations or views expressed in this report. Disclosures: The price target and rating history for Matador Resources Co. prior to February 1, 2023 reflect MKM’s published opinion prior to the acquisition of MKM Partners, LLC by Roth Capital Partners, LLC. Within the last twelve months, ROTH Capital Partners, or an affiliate to ROTH Capital Partners, has received compensation for investment banking services from Matador Resources Co.. Within the last twelve months, ROTH Capital Partners, or an affiliate to ROTH Capital Partners, has managed or co-managed a public offering for Matador Resources Co. Not Covered [NC]: ROTH Capital does not publish research or have an opinion about this security. ROTH Capital Partners, LLC expects to receive or intends to seek compensation for investment banking or other business relationships with the covered companies mentioned in this report in the next three months. The material, information and facts discussed in this report other than the information regarding ROTH Capital Partners, LLC and its affiliates, are from sources believed to be reliable, but are in no way guaranteed to be complete or accurate. This report should not be used as a complete analysis of the company, industry or security discussed in the report. Additional information is available upon request. This is not, however, an offer or solicitation of the securities discussed. Any opinions or estimates in this report are subject to change without notice. An investment in the stock may involve risks and uncertainties that could cause actual results to differ materially from the forward-looking statements. Additionally, an investment in the stock may involve a high degree of risk and may not be suitable for all investors. No part of this report may be reproduced in any form without the express written permission of ROTH. Copyright 2024. Member: FINRA/SIPC. ( Companies Mentioned: MTDR:NYSE, ) Full Article
b Renewable Power Co. Posts Strongest Fiscal Year Thus Far By www.streetwisereports.com Published On :: Tue, 05 Nov 2024 00:00:00 PST Source: Streetwise Reports 11/05/2024 Operationally, the company's renewable energy generation was up 397% year over year. Discover the many potential catalysts for the stock.Revolve Renewable Power Corp. (TSXV:REVV; OTCQB:REVVF) released its strongest financial results since going public in 2022, those for fiscal year 2024 (FY24) ended June 30, 2024, the company announced in a news release. "FY24 marked significant progress for the company as it continues its transition to an owner and operator of renewable energy projects, incorporating a focus on building long-term recurring revenues and cash flow for the business," the release noted. This company, headquartered in British Columbia, develops utility-scale solar, wind, hydro, and battery storage projects in North America. The Revolve Renewable Business Solutions division installs and operates sub-20-megawatt, behind-the-meter distributed generation assets. FY24 revenue of US$6.7 million (US$6.7M) exceeded guidance by 35% and surpassed FY23 revenue by 509%. Significant contributors to total revenue for this latest fiscal year were deferred revenues and milestone payments of US$4.25M from the sale of the Bouse and Parker projects to ENGIE. Completion of the WindRiver Power Corp. acquisition in February added $671,738 of total revenue. In the future, WindRiver business is projected to generate recurring revenue of US$1.8M on a 12-month basis. Adjusted EBITDA in FY24 also was up year over year (YOY), at US$2.7M versus US$1.5M of guidance and (US$2.1M) in FY23. The gross margin in FY24 was strong at 96%. This was due to increased recurring revenues from the distributed generation portfolio, low operating costs of the rooftop solar projects therein, the addition of operating utility-scale projects in Canada, and sale proceeds from utility-scale projects in the U.S. FY24 resulted in a net income of US$2.6M, whereas FY23 saw a net loss of US$2.3M. As for the balance sheet, at FY24's end, Revolve had US$3.2M in cash. Total liabilities were US$10M, up from US$2.6M in FY23 due to nonrecourse debt taken on via the WindRiver acquisition plus additional loans granted by RE Royalties Ltd., a Canadian royalty finance company, throughout FY24. Operational Progress Made Operationally, in FY24, according to the release, Revolve generated 8,048,729 kilowatt-hours (8,048,729 kWh) of renewable energy, up 397% from 1,618,456 kWH the year before. The main drivers were continuing output from the company's operational distributed generation portfolio and power produced at the Box Springs wind farm. During the 15 months between July 1, 2023, and Oct. 31, 2024, Revolve added of 76.1 megawatts (76.1 MW) net of development hydro projects in Canada through the WindRiver acquisition and 480 MW of new greenfield development projects in Canada and the U.S. These took the total of Revolve's utility-scale projects under development to 3,015 MW. The company made significant progress on its 20 megawatt (20 MW)/80 MWh Vernal BESS battery storage project and 49.5 MW Primus wind projects, now in the late stage of development and expected to reach ready-to-build status at the end of 2025 (2025E). Revolve is still building its two distributed generation assets in Mexico, totaling 3.45 MW. Permitting work continues on the 3 MW CHP project continues, and the final commissioning of the 450-KW-peak rooftop solar project is taking place. The distributed generation project pipeline remains at about 150 MW, and efforts are ongoing to sign additional power purchase agreements for new projects from it. Also, Revolve recently announced its acquisition of a 30-MW-peak solar development project in Alberta, Canada, and expects a 20-MW-peak first phase will be ready for construction by 2025E. Independent Power Producer Revolve is a revenue-generating, renewable-focused independent power producer formed in 2012 to capitalize on the growing global demand for renewable power, according to its October 2024 Corporate Presentation. The company began as solely a developer of utility-scale projects, a line of business that provides investors access to higher returns. Currently, the company has two projects under construction, the ones in Mexico and 3,000-plus MW worth of projects in development in Canada, the U.S., and Mexico. To date, Revolve has developed and sold more than 1,550 MW of utility-scale projects and is now targeting 5,000 MW under development. Today, Revolve is also an owner-operator of renewable energy distribution generation projects that provide recurring revenue and cash flow via long-term power purchase agreements. Currently, the portfolio contains 150-plus MW of generation projects in Canada and Mexico. The company will continue expanding this line of business through organic growth and mergers and acquisitions (M&A) activity. Revolve's management team has a successful track record in taking renewable energy projects from greenfield to ready-to-build status and in selling them to large operators. Collectively, it has generated about US$23M in revenue historically from the sale of 1,550 MW of development assets and has raised US$10.3M in equity capital. Significant Sector Growth Forecasted The transition to net zero emissions continues driving the renewable energy industry after nearly 200 countries at the COP28 UN Climate Change Conference in December 2023 pledged to triple global capacity by the end of this decade. In a report last month, the International Energy Agency (IEA) forecasted global renewable capacity reaching almost 11,000 gigawatts (GW) by then, reflecting 2.7 times growth, falling short of the goal. Solar Photovoltaic (PV) Power: Of the growth predicted for renewable energy during this period, solar photovoltaic power will make up 80% of it, according to the IEA, due to its increasing economic attractiveness in most countries. "At the end of this decade, solar PV is set to become the largest renewable source, surpassing both wind and hydropower," the agency wrote. Hydropower currently is the top source worldwide. Wind Power: Wind power will account for 15% of all forecasted renewable capacity growth, noted the IEA. This sector has suffered recently from macroeconomic factors and supply chain difficulties, but it is expected to recover. Global wind capacity is projected to expand between 2024 and 2029 at double the rate it grew between 2017 and 2023. "Policy changes concerning auction design, permitting, and grid connection in Europe, the United States, India, and other emerging and developing economies are expected to enhance project bankability and help the wind sector recover from recent financial difficulties," the article noted. Hydropower: As for hydropower, capacity is continuing to grow consistently, noted the IEA, due primarily to efforts by China, India, Africa and the Association of Southeast Asian Nations region. In North America, the U.S. is expected to be the biggest market for hydropower, according to Mordor Intelligence. Between 2024 and 2029, the market is forecasted to expand at a compound annual growth rate of 1%, spurred by demand for renewable energy and investments in hydropower plants. "The technological advancements in efficiency and decrease in the production cost of hydropower projects are expected to create ample opportunity for market players," the article noted. The Catalysts: Results of Business as Usual As Revolve continues effecting its growth strategies, numerous potential stock-boosting events should occur, according to its corporate presentation. Catalysts resulting from ongoing efforts include further M&A transactions, signing additional power purchase agreements, and bringing new distributed generation projects online. wo increasing revenue and cash flow growth. Specifically, the company reaching its goals of advancing 70 MW of the BESS and Wind projects to ready-to-build status as well as 30 MW of solar in Canada, in 2025. These have the potential to generate material revenue and add value. Another catalyst is Revolve achieving ready-to-build status for its two wind projects in Mexico, the 103 MW El 24 and the 400 MW Presa Nueva. The company's ultimate goal with these assets is to partner on or sell them. [OWNERSHIP_CHART-10982] Finally, payments toward the remaining US$45–55M balance still owed to Revolve regarding the ENGIE sale could boost its stock. Ownership and Share Structure About 60% of the company is owned by insiders and management, Revolve said. Top shareholders include Joseph O'Farrell with 13.21%, Roger Norwich with 12.15%, the CEO and Director Stephen Dalton with 6.01%, President and Director Omar Bojorquez with 4.82%, and Jonathan Clare with 1.84%, according to Reuters and the company. The rest is retail. Revolve has a market cap of CA$17.96M. It has 63.04M outstanding shares and 38.75M free float traded shares. Its 52-week high and low are CA$0.50 and CA$0.21 per share, respectively. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures: As of the date of this article, officers and/or employees of Streetwise Reports LLC (including members of their household) own securities of Revolve Renewable Power Corp. Doresa Banning wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. For additional disclosures, please click here. ( Companies Mentioned: TSXV:REVV;OTCQB:REVVF, ) Full Article
b CAAM exhibits the diversity of the disappearing black woman By www.scpr.org Published On :: Thu, 15 Jun 2017 14:17:26 -0700 "Dispersion" (detail). Acrylic ink and paint on canvas. (Courtesy of Kenyatta A.C. Hinkle); Credit: Rosalie Atkinson | Off-Ramp®Kenyatta A.C. Hinkle's "The Evanesced" was inspired by the #SayHerName movement against police violence, as well as Los Angeles's Grim Sleeper serial killer. Hinkle depicts black women in the nude, twisting and writhing, as though they're sinking back into the canvas. Or are they reemerging from it? Deputy Director of the California African American Museum Naima Keith says Hinkle's exhibit looks at the "historical present," the way in which history still affects us today, harkening back to slavery and Jim Crow. Keith says the main issue Hinkle is addressing is the invisibility of black women, especially those who are abused or in danger. Hinkle was particularly inspired by the South LA serial killer "The Grim Sleeper." He is accused of murdering over one hundred women from the 1980's onward, until being captured in 2007. Many of his victims were women of color according to the Los Angeles Police Department. "He had been killing prostitutes and runaways and drug addicted women," says Keith, noting that some saw these deaths as occupational hazards. Most of Hinkle's subjects in the paintings and sketches in "The Evanesced" are clearly nude. This was a deliberate choice to showcase femininity, according to Keith. She says: She’s talking about being women... There’s love, there’s joy, there’s pain. All things we experience as all women... But [nudity], I think, allows us to focus on the female form, not necessarily get caught up on what they are wearing or what they’re doing. In the artwork, viewers can see that every face, body, and hair style is completely unique to each sketch or painting. Keith says this helps the viewer appreciate the diversity amongst women of color. She says: You have women that are smiling. You have women that are looking at you- you know- lovingly, shyly. Not every one, not every image in the show is about negativity, disappearance, or sadness. There is a bit of celebration. There’s interaction between multiple women. That’s what makes the body of work so interesting: it’s not just seeing women of color through one lens. There’s the possibility of seeing them through, like I said, disappearance, and also the freedom to have a wide range of emotions. There is one painting that continues to draw Naima Keith back to it. It is called "Uproot 2017" and it features a feminine figure with three exposed breasts. She says this painting speaks to her about motherhood and the connection women have with their changing bodies. Keith says: I asked Kenyatta why she depicts women with multiple [extra] breasts and we had a conversation about being moms. Kenyatta and I are both mothers of young children... As moms, we just kinda talked about how things aren't what they used to be, in terms of where they used to be. Like I said, becoming mothers, you have this different relationship with your body in relation to someone else. Kenyatta A.C. Hinkle's "The Evanesced" runs at the California African American Museum through June 25, 2017. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Off-Ramp's producer on the first time he ever heard public radio (it was Off-Ramp) By www.scpr.org Published On :: Wed, 21 Jun 2017 13:22:06 -0700 Hollywood billboard queen, Angelyne was featured on the first Off-Ramp episode producer Chris Greenspon ever heard.; Credit: Creative Commons via Flickr user Thomas Hawk Chris Greenspon and Rosalie Atkinson | Off-Ramp®After a few semesters of college radio at Mt. San Antonio College, I landed my first radio job: Board Operator! At struggling KFWB Newstalk 980. My career in radio began the way it does for so many, working odd hours and weekends. A few months into my new gig, I was leaving for work and I thought, “You know, if I’m going to work in radio, I should listen to the radio.” I drove over the bridge on Hacienda Boulevard in La Puente, heading towards the 60, and right in front of my on-ramp, there was a big, orange billboard for KPCC. Why not 89.3? The first thing I heard (and I should clarify that this was also my first time ever hearing public radio) was Janis Joplin getting her star on the Hollywood Walk of Fame, on Off-Ramp. Clive Davis, the CBS A&R executive who signed Joplin, told the crowd about how Joplin had suggested sealing their new relationship by having sex (though he demurred), and that his heart was broken when she died. Then Kris Kristofferson sang “Me & Bobby McGee,” and I was smiling, until I heard a chorus of hippies singing "Mercedes Benz." Pee-yew! “Should I stay?” I asked myself. How could I not, when someone named Dylan Brody came on and told a story about letting his dogs poop on the neighbor’s lawn? But then, the real cheese, for a 20-something year old, biracial kid who loved space ships and tough punk girls; "Love and Rockets" cartoonist Jaime Hernandez talking about drawing for Junot Diaz. All this was to say nothing of the loud, defiant-sounding host, who kept saying. "This is Off-Ramp, I’m John Rabe." I listened to him slide between all of these topics, and even report from the field himself, talking about museums in a way that wasn’t – boring. After a few more pieces and a few more uses of the Off-Ramp theme song, I had a new favorite show. And I suspect a few other people did too. That was November 2013. Five months later, I was on the show. At the end of the episode, I noticed that they had an intern in the credits, and after many repeated scourings of the KPCC careers page, the position finally opened up. So what’d I do? I went out with my chintzy audio recorder, and recorded a story so if I got an interview, I wouldn’t go in empty-handed. I didn’t get the internship then, but John did buy the piece. Remember the one about the Burmese Café run by an ex-biologist? I kept freelancing after that, and honestly, I got a lot of my ideas from stuff that Off-Ramp wasn’t doing. John would have Angelyne, and her famous Hollywood billboard, but what about the giant neon sign at Rose Hills Cemetery in Pico Rivera? Kevin Ferguson would hang out with Mike Watt from the Minutemen, but what about punk supergroup, the Flesh Eaters? And could we talk about a domestic violence shelter in a Thanksgiving Special, or the fact that a home-abortion movement started in Los Angeles? John eventually asked me to intern after turning the Jim Tully mini-documentary in, and even after joining the company, writing these kinds of stories for Off-Ramp was still not easy, but there was room for all of them. I would be beyond thrilled if somebody heard even one of them when they heard Off-Ramp for the first time. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Interview in the mausoleum with relics expert Elizabeth Harper By www.scpr.org Published On :: Wed, 21 Jun 2017 18:11:11 -0700 Elizabeth Harper, a relics expert, at Mountain View Cemetery in Altadena; Credit: John Rabe John Rabe | Off-Ramp® "Reach a certain moment in your life, and you discover that your days are spent as much with the dead as they are with the living." – Paul Auster This has been one of my favorite quotes for a long time. To me it means that when you get older and your friends, relatives, and heroes start dying, you have a choice. You can either stop thinking about them because they're dead, giving up, as it were, the pleasure of their company; or you can keep them in your life. To me, that's not denial; it's being realistic. So, it makes sense that I felt a kindred spirit with Elizabeth Harper, who keeps the website All the Saints You Should Know, when we met at a beautiful mausoleum at Mountain View Cemetery in Altadena to talk about the history of cemeteries, relics, castrated Italian avuncular mummies, and the best spots in Los Angeles to commune healthily with death. Elizabeth will be part of the team when Atlas Obscura leads tours of The Cathedral of Our Lady of the Angels on Saturday, July 1. It's billed as "A celebration of life, death, architecture, and the patron saint of Los Angeles." Here are some highlights of my mausoleum conversation with Elizabeth Harper: At first glance, she says, all of the tombs are very similar. And that was one of the things, when we started making modern cemeteries, outside the city lines, they wanted them to be regular and not so expressive and macabre. But people leave little things behind. On a lot of these (crypts), you can see a little emblem of something that was important to them. If they were a Mason or if they served in the Army. I like the (cremains) urns that are shaped like books. I have a friend who is a librarian and she was very taken with the idea of being in a book. Napoleon instituted the Edict of Saint-Cloud, which mandated that cemeteries must be outside city limits (for health reasons) and must be toned-down (for no good reason). People did not like the edict. There's a very famous poem called Sepulchers by Ugo Foscolo that was written in protest, that said, essentially, looking upon the graves of strong men strengthens the mind and the spirit. From Slate: Photographing the Real Bodies of Incorrupt Saints, by Elizabeth Harper Elizabeth often writes about cemeteries and tombs and sometimes posts photos of bodies, which causes a "certain segment" to assume she has no experience with death, or she wouldn't presume to do such a thing. What I want to put out there is that we have this pervasive idea that we grieve and move on, and this moving on is very important, and I think there are multiple ways to incorporate the idea of death in your life, to get used to the idea, without forgetting, that's more of a way of memorializing. When I take these pictures, I'm very aware that these are real people, and I think of myself, what I will be one day, and people I love, who are already there. Make sure to listen to our entire interview in the audio player to hear Elizabeth's 3 top spots in Los Angeles to consider the place of death in our lives, and to hear about poor old Uncle Vincent, a neutered naked mummy in a small town in Italy who has a large fan base. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Searching for Ruth Batchelor: founder of the LA Film Critics Association By www.scpr.org Published On :: Fri, 23 Jun 2017 08:20:48 -0700 The back cover photo splash from Ruth Batchelor's album "Songs for Women's Liberation: Reviving a Dream"; Credit: R. H. Greene | Off-Ramp®I’ve been a member of the LA Film Critics Association since 1999. LAFCA is a good group - collegial and filled with real movie lovers. But it has a problem. It's a professional organization, meaning a baseline for membership is you have to have a job, and film criticism is overwhelmingly white and male. 78 percent of the top critics listed on RottenTomatoes are male, and women write only 18 percent of the major reviews. So LAFCA is like the profession itself: overwhelmingly a platform for white men. It's trying to diversify. It has been for years. But how do you do that when the pool you draw from has a huge institutional bias? According to film critic Claudia Puig, "Criticism has been a white male dominated field for very long. And it continues to be. And not just white males, but middle aged." Claudia is the current LAFCA president - and a legendary critic, who wrote lead reviews for 14 years at USA Today, and now appears regularly on KPCC’s Film Week. "Very few movies pass the Bechdel Test. Women are often just girlfriends, wives, mothers. They don't get to have a story arc of their own. But if you had more women reviewing these movies, they would point out certain things that people might not notice as potentially offensive. Because we have been harassed, or we have experienced any number of things. It's something I've grappled with through my entire career." - Claudia Puig I'm on a committee with Claudia for the LA Film Critics. The concept is to mentor young writers - to generate diversity, from the ground up. One idea is to have a scholarship for aspiring female film critics. We thought it would be good to name it after a prominent woman from the group's past. So I went to Myron Meisel, who joined LAFCA in 1979, just four years after it formed, and I asked him, "Is there a woman you can think of who played an especially prominent role in the history of the LA Film Critics Association?" "Oh!," Myron said. "Ruth Batchelor was the founder and driving force..." "Wait, what?" I asked. "LAFCA was founded by a woman?" "We weren't shocked. You had Ruth, who was very much concerned with creating a Los Angeles equivalent to the New York Film Critics Association. Which she largely pulled together by force of will. While Ruth was the moving force, you really can't discount her ability to martial the enthusiastic support of Charles Champlin as a co-founder, and the imprimatur of the Los Angeles Times behind him. Ruth had an enviable ability to make everything she undertook seem inevitable." - Myron Meisel It's poignant, isn't it? And a little creepy. A prestigious group commits to gender diversity, and somehow, it doesn't have the institutional memory to know that the pivotal figure in its history was a woman. How could we forget Ruth? Batchelor was nothing if not memorable. Before she became a pundit, she was a successful pop songwriter in the style of Neil Sedaka, or Goffin and King. She wrote dozens of songs, recorded by everybody from Phil Spector to the Partridge Family. She wrote Elvis Presley numbers, including "Cotton Candy Land," which might be the most hated track in the Presley catalogue. But Batchelor also wrote "Where Do You Come From?", which is beautiful. Elvis Presley performing Ruth Batchelor's "Where do you come from?" Where do you come from, Ruth? It wasn't easy to find out. Batchelor's New York Times obituary was full of false leads. It said she was a critic for National Public Radio. She wasn't, but when NPR searched their archives, they unearthed a lead: a Film Comment article from 1982, where Batchelor is described as "Ruth Batchelor of National Public Radio's 'As it Happens.'" "As It Happens" airs on Canada's CBC. So I placed a call. And I waited. Meanwhile, I found a blog post about Batchelor as a songwriter on an excellent site called "Zero to 180 - 3 Minute Magic." The title of the post was riveting: "First 'Women's Liberation LP.'" It turns out in 1971, Ruth Batchelor self-produced and financed a concept album called "Songs for Women's Liberation: Reviving a Dream." Myron Meisel told me about Ruth's earthy sense of humor, and it's right there in the first write-up's, where her working title is "A Quarter for the Ladies Room." A Billboard article from August 1971 quotes Batchelor about the album: "Right now I have an album of dirty Women's Liberation poems recorded, and I'm trying to sell the master." Then she laughs. "The last record company I recorded for folded." Batchelor shopped her record. There were no takers. But Batchelor proved unstoppable. She created her own record company and called it Femme Records. Then she put out what the leftist journal Broadside called "the first feminist record album," all by herself. "Reviving a Dream" is forgotten, bordering on lost. It's never been available for streaming, or released on CD. Batchelor's record is a pastiche of radio styles from her era. There's Joan Baez folk, two drawling country laments, even some call and response stuff Batchelor probably learned from Phil Spector and his girl groups. Are Batchelor's songs any good? They're amazing. Amazing just because they exist. She fits into the churning sea of anonymous faces so seamlessly it takes awhile to realize: She's Ruth Batchelor. The woman who founded the LA Film Critics. A group currently struggling with gender diversity. LAFCA prez Claudia Puig agreed to an interview knowing it had to do with LAFCA, but not what it was about. I played her Batchelor's song "Drop the Mop." Batchelor intended it as an anthem, scored to a tempo of marching feet. The listen was awkward - like force feeding a roommate your iTunes playlist. Claudia took notes the whole time, to occupy her critical mind, but I could see when it ended that she was moved. "Yeah, it's a really interesting song," Claudia said. "My reaction is sort of...ummm..." Claudia hesitated, looking for words. "And this was the origin of the group. Yeah. It really kind of... It is really interesting. I'd never heard of her. She was right there, fighting that fight." "And here, we were looking for an avatar," I said. "Right. Right. It means something. This is a really important discovery that you made." A piece of the portrait was missing - an essential one. It came courtesy of Kevin Robertson, a producer for "As It Happens" at the CBC. Batchelor had been the show's "Hollywood Correspondent" in the early 1980s. There was audio in the archives. Kevin provided me with five MP3s. Batchelor's CBC brand was gender traditional. She was the tinseltown gadfly, a niche created by Hedda Hopper and Louella Parsons in the 1930s. There was gossip about Burt Reynolds and Loni Anderson. Richard Burton's widow. Marvin Hamlisch. TV's "Gomer Pyle." It was kitsch heaven, so I wasn't disappointed. Not exactly. But it was still a bit like listening to Wonder Woman try to be ordinary, because hey, we all gotta eat. Ruth Batchelor's "Mr. Principal" The LA Film Critics get a cameo in Batchelor's Oscar season broadcast, when she mentions her LAFCA Awards vote. For awhile, I thought that would be the only audio connecting the "As It Happens" Ruth Batchelor to the feminist fireball she wanted to be. Then Batchelor starts riffing on "Partners," a buddy cop farce about a straight cop who goes undercover as a gay man. The film had sparked protests from the gay community. Batchelor is unsympathetic, which is surprising in a civil rights pioneer. Her reasoning is devastating. "You know if women got angry every time there was a movie against women," Batchelor says, "there wouldn't be any movies." Batchelor died of cancer early - she was just 58. 25 years later, men still direct most mainstream movies - 93 percent as of 2015. They have 70 percent of the speaking parts, and play 88 percent of the leads. While women get to be naked twice as often in American movies. Men review almost all movies too. Maybe that's why Ruth Batchelor founded the LA Film Critics. Because she lived in that world. She covered it. Spoke to it. Fought hard against it. And then left behind a hidden legacy. "She is our avatar," Claudia says, as our interview time runs out. "It sort of makes me want to redouble our efforts to honor her spirit." This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Food writer Russ Parsons brings Rabe a pie (not in the face) for the Off-Ramp finale By www.scpr.org Published On :: Wed, 28 Jun 2017 13:01:07 -0700 Former LA Times food writer Russ Parsons offers John Rabe a piece of pie, in John's Mercedes; Credit: John Rabe/KPCC John Rabe | Off-Ramp®Semi-retired, former LA Times food writer Russ Parsons appeared often on Off-Ramp over the years, helping to explain the city’s communities through their food, as well as giving solid cooking advice. For the final edition of Off-Ramp, John picked up Russ at Jongewaard's Bake-N-Broil, a Long Beach institution. Parsons brought John an olallieberry pie (a cross of 'Black Logan' blackberries and youngberries), whilst the inimitable Parsons -- author of "How to Pick a Peach: The Search for Flavor from Farm to Table" and "How to Read a French Fry: And Other Stories of Intriguing Kitchen Science" -- opted for the coconut cream. Listen to the audio for John and Russ' observations on how food brings the disparate cultures of Los Angeles together, and to hear about which part of hosting Off-Ramp is as humbling for John as it is for Parsons when readers tell him they cook his food at Thanksgiving. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Benmont Tench - of Tom Petty and the Heartbreakers - says goodbye to John with the most Off-Rampy song ever By www.scpr.org Published On :: Wed, 28 Jun 2017 13:47:00 -0700 ; Credit: John Rabe/KPCC John Rabe | Off-Ramp®Off-Ramp fan, KPCC member (!), and Tom Petty and Heartbreakers keyboardist Benmont Tench III joined John in his old Mercedes with his large, but portable Casio. Tench has lived in the hills of Tarzana for decades, in a perfectly good house, but in the 100-degree heat, John outfitted his car with condenser mikes to record a farewell ode to Off-Ramp, Tench's "Like the Sun." The full band version of Benmont Tench III's "Like the Sun" "Like the Sun" helped Tench get back in the songwriting groove a decade ago after he burnt out on being professional songwriter in Nashville. He based the lyrics on tours of Los Angeles given to him by a friend, and takes the listener (with his Southern accent) from a restaurant called Michoacan to a hill top tent city. Tench also told John how he and his wife Alice explore Los Angeles. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Queena Kim, Off-Ramp's first producer, sheds light on the show's beginnings By www.scpr.org Published On :: Wed, 28 Jun 2017 15:33:26 -0700 Off-Ramp producer Queena Kim acts on behalf of millions of Angelenos. The meter didn't stand a chance. ; Credit: John Rabe/KPCC John Rabe | Off-Ramp®Off-Ramp began eleven years ago, just as digital technology was beginning to overtake radio. No more cassette tape or mini-discs; host John and producer Queena Kim thought they could take on all of Los Angeles with two digital audio recorders and a different approach to public radio. Short-handed as they were, John and Queena had to adopt slash-and-burn tactics to get each show produced on time. The majority of interviews were conducted in the field; at the homes, workplaces, and favorite hang-outs of their subjects (instead of waiting for guests to come to the station) and many of the stories were edited as simple two-way interviews with life in Southern California picked up as ambient, background noise. After all, a show called Off-Ramp had better be ready to brave some LA traffic. At this juncture, John feels free to say what he has always wanted to, but hasn't for fear of self-aggrandizement: "I think we were trendsetters. I think Marketplace and NPR heard the stuff we were doing, and started doing stuff like it." Once again, Kim chalks it up to being in the right place at the right time technologically, and the two person team's willingness to break out of the old-school, public radio way writing a story: with a very clear sonic difference between studio narration and field audio. Of course, it wasn't just Marantz recorders and minimal rewriting that gave Off-Ramp its flavor. There was a whole lot of weird spewing up out of Los Angeles during the show's formative years and Kim's tenure (2006-2010). She recalls covering a ten-theremin orchestra at Disney Hall, and the excitement of working on a show that let her (and the listeners, vicariously) do things she always wanted to do. "It was almost like having a free pass to the city." In order to capture what was new and exciting, John and Queena both agree that it was absolutely vital to abandon the reporter's instinct for safely packaging the story ahead of time. John cites his editor at Minnesota Public Radio's philosophy, Mike Edgerly; "Go find what the story is, go out and explore and figure out what the story is. Don't figure it out at your desk first." The collaboration between John's ideas and Kim's sense of logistics formed a dialectic relationship, valuing the "third, better idea" over either of their original perspectives. In light of that, John says Queena Kim was the perfect person with whom to start Off-Ramp. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Mayor Garcetti's Q&A in John's car was almost over... until Hizzoner saw the backgammon game By www.scpr.org Published On :: Thu, 29 Jun 2017 14:41:46 -0700 Off-Ramp host John Rabe and Mayor Eric Garcetti playing backgammon in John’s car. Julian “The First Lady of Off-Ramp” Bermudez in the passenger seat with camera. ; Credit: Andrea Garcia John Rabe | Off-Ramp®John Rabe’s last show coincides with Eric Garcetti’s inauguration for his second term as Mayor of Los Angeles. In John's car, the two talked about: The joys of exploring Los Angeles The time the future Mayor's mom and dad took his drivers' license away Where Justin Trudeau should visit when he comes to LA And how the drop in crime has led to more people doing the Off-Ramp thing The Mayor also did some slam poetry, and then played a competitive game of backgammon. Listen with the audio player to see who was brown and who was white. And listen to Off-Ramp on the radio to find out who won the game! (Saturday at noon/Sunday at 6pm) This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b George Takei on how he took his internment camp musical, 'Allegiance,' to Broadway By www.scpr.org Published On :: Fri, 16 Feb 2018 12:53:00 -0800 Brad and George Takei, the new typical American married couple.; Credit: John Rabe/Grant Wood/Michael Uhlenkott John Rabe | Off-Ramp®UPDATE: “Allegiance” will be performed Feb. 21-April 1, 2018, at the Aratani Theater at the Japanese Cultural and Community Center in downtown L.A.'s Little Tokyo. ORIGINAL STORY: In an intimate interview, George Takei tells Off-Ramp host John Rabe about crafting the Japanese-American internment camp history into compelling Broadway musical theater. "Allegiance," with Takei, Lea Salonga and Telly Leung, played at the Longacre Theater. George Takei and his husband Brad were putting their house in mothballs when I arrived for our interview in August. They'd already been spending a lot of time in New York because of George's recurring role on "The Howard Stern Show," but now, with the Broadway opening of "Allegiance" just a couple months away, they were preparing to move for as long as the musical brings in the crowds. While Brad went off to deal with the mundane domestic tasks around the move, I sat with George in their living room to talk about turning one of America's most shameful episodes — the internment of some 120,000 loyal Japanese-Americans during World War II — into a musical that could make it on the Broadway stage. George, you just sent an email to your fans with the subject line: "I've Waited 7 Years to Send You this Email. Seven years!" Inside, you wrote: "Few things are as difficult and complex as taking a show to Broadway. It's both thrilling and terrifying." What was terrifying? "The terrifying part is, you've poured your passion, your energy, your resources ... you make all that investment in that project, and then you're hoping the seats are going to be filled.That 'what if' is terrifying. But in San Diego, we had a sold-out run and broke their 77-year record. But now we're going to Broadway, and that same fear is there. Will they come? What will the critics say? Because it's life or death." It took a long time just to get a Broadway theater. "It took a long time to get a theater.You think there are a lot of Broadway theaters, but there are even more productions that want those chunks of New York real estate. So we thought we'd get in line. But then the other discovery we made is that the theater owners have relationships with grizzled old producers who have brought them a vast fortune with enormous hits, and they can cut in line. They have a track record. And so, 'will we ever get a theater' became a big question. But we have this time now — let's use it creatively, productively." So, Takei says, the team tweaked the show, removing parts that didn't work didn't advance the story, inserting numbers that worked better and kept the story moving. They doubled down on social media, building and proving demand in the show. "We have a Shubert theater (the Longacre), and Bob Wankel is head guy there, and I remember pouring my heart out, telling the story of my parents, hoping that touches. And he was understanding, but I understood his problem, too. Everybody is trying to get a theater and he has to make a good business decision and was initially skeptical. An internment camp musical? But music has the power to make an anguished painful situation even more moving, even more powerful. It hits you in the heart." Highlights from "Allegiance" at the Old Globe in San Diego This is your Broadway debut, right? Are you petrified? "Yes, yes. I've done a lot of stage work, and I've done a lot of public speaking, but it's Broadway, and I'm a debutante... at 78 years old! And it's the critics, too. The New York Times, Ben Brantley. That's who I'm going to be facing, and so it's both exciting and absolutely filling me with ecstasy, but what makes it ecstatic is the fear." For much more of our interview with George Takei, listen to the audio by clicking the arrow in the player at the top of the page ... and hear George Takei and John Rabe's duet of "Tiny Bubbles." This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Brookhaven completes LSST's digital sensor array By news.science360.gov Published On :: 2019-08-22T07:00:00Z Full Text:After 16 years of dedicated planning and engineering, scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory have completed a 3.2 gigapixel sensor array for the camera that will be used in the Large Synoptic Survey Telescope (LSST), a massive telescope that will observe the universe like never before. The digital sensor array is composed of about 200 16-megapixel sensors, divided into 21 modules called "rafts." Each raft can function on its own, but when combined, they will view an area of sky that can fit more than 40 full moons in a single image. Researchers will stitch these images together to create a time-lapse movie of the complete visible universe accessible from Chile. Currently under construction on a mountaintop in Chile, LSST is designed to capture the most complete images of our universe that have ever been achieved. The project to build the telescope facility and camera is a collaborative effort among more than 30 institutions from around the world, and it is primarily funded by DOE's Office of Science and the National Science Foundation.Image credit: SLAC National Accelerator Laboratory Full Article
b Genetic redundancy aids competition among symbiotic bacteria in squid By news.science360.gov Published On :: 2019-08-28T07:00:00Z Full Text:The molecular mechanism used by many bacteria to kill neighboring cells has redundancy built into its genetic makeup, which could allow for the mechanism to be expressed in different environments, say researchers at Penn State and the University of Wisconsin-Madison. Their new study provides insights into the molecular mechanisms of competition among bacteria. "Many organisms, including humans, acquire bacteria from their environment," said Tim Miyashiro, a biochemist and molecular biologist at Penn State and the leader of the research team. "These bacteria can contribute to functions within the host organism, like how our gut bacteria help us digest food. We're interested in the interactions among bacteria cells, and between bacteria and their hosts, to better understand these mutually beneficial symbiotic relationships." Cells of the bioluminescent bacteria Vibrio fisheri take up residence in the light organ of newly hatched bobtail squid. At night, the bacteria produce a blue glow that researchers believe obscures a squid's silhouette and helps protect it from predators. The light organ has pockets, or crypts, in the squid's skin that provide nutrients and a safe environment for the bacteria. "When the squid hatches, it doesn't yet have any bacteria in its light organ," said Miyashiro. "But bacteria in the environment quickly colonize the squid's light organ." Some of these different bacteria strains can coexist, but others can't. "Microbial symbioses are essentially universal in animals, and are crucial to the health and development of both partners," says Irwin Forseth, a program director in the National Science Foundation's Division of Integrative Organismal Systems, which funded the research. "The results from this study highlight the role small genetic changes can play in microbe interactions. Increased understanding will allow us to better predict organisms' performance in changing environments."Image credit: Andrew Cecere Full Article
b Could graphene-lined clothing prevent mosquito bites? By news.science360.gov Published On :: 2019-08-29T07:00:00Z Full Text:A new study shows that graphene sheets can block the signals mosquitoes use to identify a blood meal, potentially enabling a new chemical-free approach to mosquito bite prevention. Researchers showed that multilayer graphene can provide a twofold defense against mosquito bites. The ultra-thin yet strong material acts as a barrier that mosquitoes are unable to bite through. At the same time, experiments showed that graphene also blocks chemical signals mosquitoes use to sense that a blood meal is near, blunting their urge to bite in the first place. The findings suggest that clothing with a graphene lining could be an effective mosquito barrier.Image credit: Hurt Lab/Brown University Full Article
b Scientists recover the first genetic data from an extinct bird in the Caribbean By news.science360.gov Published On :: 2019-09-03T07:00:00Z Full Text:Scientists have recovered the first genetic data from an extinct bird in the Caribbean, thanks to the remarkably preserved bones of a Creighton's caracara in a flooded sinkhole on Great Abaco Island in the Bahamas. Studies of ancient DNA from tropical birds have faced two formidable obstacles. Organic material quickly degrades when exposed to heat, light and oxygen. And birds' lightweight, hollow bones break easily, accelerating the decay of the DNA within. But the dark, oxygen-free depths of a 100-foot blue hole known as Sawmill Sink provided ideal preservation conditions for the bones of Caracara creightoni, a species of large carrion-eating falcon that disappeared soon after humans arrived in the Bahamas about 1,000 years ago. Florida Museum of Natural History researcher Jessica Oswald and her colleagues extracted and sequenced genetic material from the 2,500-year-old C. creightoni femur. Because ancient DNA is often fragmented or missing, the team had modest expectations for what they would find –- maybe one or two genes. But instead, the bone yielded 98.7% of the bird's mitochondrial genome, the DNA most living things inherit from their mothers. The mitochondrial genome showed that C. creightoni is closely related to the two remaining caracara species alive today: the crested caracara and the southern caracara. The three species last shared a common ancestor between 1.2 and 0.4 million years ago. "This project enhanced our understanding of the ecological and evolutionary implications of extinction, forged strong international partnerships, and trained the next generation of researchers," says Jessica Robin, a program director in National Science Foundation's Office of International Science and Engineering, which funded the study.Image credit: Florida Museum photo by Kristen Grace Full Article
b Premier Bank, Mastercard, Tappy Technologies launch Tap2Pay By thepaypers.com Published On :: Fri, 18 Oct 2024 14:27:00 +0100 Premier Bank, in partnership with Full Article
b Thunes unlocks global mobile wallet payments via Swift By thepaypers.com Published On :: Mon, 21 Oct 2024 14:43:00 +0100 Thunes has announced that its proprietary Direct Global Network... Full Article
b Mastercard expands installments, unlocking flexible payment options By thepaypers.com Published On :: Mon, 28 Oct 2024 09:37:00 +0100 Mastercard has expanded its US... Full Article
b Mambu and Kuady launch digital wallet in Latin America By thepaypers.com Published On :: Wed, 30 Oct 2024 08:03:00 +0100 Cloud banking provider Mambu has partnered with Full Article
b Pix by Proximity is introduced By thepaypers.com Published On :: Tue, 05 Nov 2024 15:46:00 +0100 Pix by Proximity has been introduced by the Central bank of Brazil,... Full Article
b Bluecode launches contactless NFC payments By thepaypers.com Published On :: Wed, 06 Nov 2024 08:39:00 +0100 Austria-based payment brand Bluecode has announced the launch... Full Article
b Boxo and Nium launch white-label remittance platform for apps By thepaypers.com Published On :: Fri, 08 Nov 2024 08:18:00 +0100 Boxo has partnered with global payments infrastructure firm Full Article
b Network International, Tamara to bring flexible payments to MEA By thepaypers.com Published On :: Fri, 08 Nov 2024 11:28:00 +0100 Full Article
b NCHL and Ant International launch NEPALPAY QR for cross-border payments By thepaypers.com Published On :: Fri, 08 Nov 2024 13:30:00 +0100 Nepal Clearing House Limited (NCHL) and Full Article
b TD Bank Group partners with TouchBistro By thepaypers.com Published On :: Mon, 11 Nov 2024 12:44:00 +0100 Canada-based financial institution TD Bank Group (TD) has... Full Article
b Everest Bank and NCHL enable cross-border QR payments with Alipay+ By thepaypers.com Published On :: Tue, 12 Nov 2024 09:40:00 +0100 Everest Bank has... Full Article
b Emirates NBD and Mastercard launch travel payment solution By thepaypers.com Published On :: Tue, 12 Nov 2024 12:19:00 +0100 Emirates NBD and... Full Article
b iDenfy launches new data crossmatch tool to improve KYB compliance By thepaypers.com Published On :: Wed, 13 Nov 2024 08:08:00 +0100 Lithuania-based iDenfy has introduced an AI-powered Data Crossmatch feature aimed at improving the Know Your Business (KYB) compliance process. Full Article
b Lean Technologies raises USD 67.5 million to scale its Pay-by-Bank and Open Banking tools By thepaypers.com Published On :: Wed, 13 Nov 2024 08:10:00 +0100 Saudi Arabia-based fintech infrastructure platform Lean Technologies has raised USD 67.5 million in a Series B funding round to scale its Pay-by-Bank and Open Banking offerings. Full Article
b Suits Me acquires the Engage business from Contis By thepaypers.com Published On :: Wed, 13 Nov 2024 09:29:00 +0100 UK-based alternative banking provider Suits Me has announced the acquisition of Engage Card customers from Solaris, with the company focusing on scaling financial inclusion in the region. Full Article
b SEB Embedded partners with Thought Machine By thepaypers.com Published On :: Wed, 13 Nov 2024 09:52:00 +0100 SEB Embedded has selected Thought Machine’s cloud-native core banking system, Vault Core, as the foundation for its latest service offering. Full Article
b Metro Bank fined nearly GBP 17 million by FCA By thepaypers.com Published On :: Wed, 13 Nov 2024 09:56:00 +0100 Metro Bank has been fined nearly GBP 17 million by the UK’s financial watchdog FCA for failings in its money-laundering controls over four years. Full Article
b Cambodia introduces Bakong Tourists App with Mastercard By thepaypers.com Published On :: Wed, 13 Nov 2024 11:12:00 +0100 The National Bank of Cambodia (NBC) has announced the launch of the Bakong Tourists App with Mastercard, with the institution aiming to optimise digital payments for tourists visiting Cambodia. Full Article
b TransferTo partners with Ecobank Group to expand financial access across Africa By thepaypers.com Published On :: Wed, 13 Nov 2024 12:04:00 +0100 Singapore-based TransferTo has partnered with the Pan-African Ecobank Group in order to expand financial access and cross-border payments across the region of Africa. Full Article
b Mbank partners with AEP for Aani Instant Payments launch By thepaypers.com Published On :: Wed, 13 Nov 2024 12:30:00 +0100 Mbank has partnered with Al Etihad Payments Company (AEP), a Central Bank of the UAE (CBUAE) subsidiary, to introduce the Aani Instant Payment Platform on its mobile application. Full Article
b IBM Hexadecimal Floating Point By blogs.mathworks.com Published On :: Sat, 25 May 2024 15:51:21 +0000 Our technical support group recently received a request for a tool that would convert IBM System/360 hexadecimal floating point numbers to the IEEE-754 format. I am probably the only one left at MathWorks that actually used IBM mainframe computers. I thought we had seen the last of hexadecimal arithmetic years ago. But, it turns out that the hexadecimal floating point format is alive and well.... read more >> Full Article History Precision Programming
b Experience With Chatbots Generating MATLAB By blogs.mathworks.com Published On :: Mon, 07 Oct 2024 14:31:38 +0000 A friend is investigating the use of generative AI in his classes. I asked two different popular chatbots to write MATLAB programs for a mathematically nontrivial problem. Both chatbots understood my query and both wrote plausible MATLAB programs, but one of the programs was not correct. My recommendation for coursework: carefully read and test programs produced by generative AI and repair any incorrect ones.... read more >> Full Article Algorithms History Programming
b Möbius, Mertens and Redheffer By blogs.mathworks.com Published On :: Wed, 23 Oct 2024 00:53:53 +0000 Recently, I have made a series of blog posts about Redheffer matrices and the Mertens conjecture. After each of the posts, readers and colleagues offered suggestions to speed up the calculations. Here is a summary of what I have learned.... read more >> Full Article Graphics History Numerical Analysis People Performance Primes
b PEA on Gold Project in Quebec Due Out This Quarter By www.streetwisereports.com Published On :: Mon, 04 Nov 2024 00:00:00 PST Source: Bryce Adams 11/04/2024 The takeout potential for the company's shares is expected to increase over the next two years as derisking continues, noted a CIBC report.O3 Mining Inc. (TSXV:OIII; OTCQX:OIIIF) updated the timeline for its flagship Marban Alliance gold project in Quebec and closed a small equity financing, reported CIBC analyst Bryce Adams in an Oct. 30 research note. "With the updated shareholder register and continued derisking of Marban, we expect that the takeout potential for O3 shares increases within the next two years," Adams wrote. O3 Mining is the third iteration of the successful Osisko Mining Inc. (OSK:TSX) model, focused on acquiring, exploring and developing mineral properties in Canada. 168% Return Implied The Canadian company was trading at the time of the report at about CA$1.12 per share, and CIBC's target price on it is CA$3 per share, noted Adams. These figures reflect a potential return for investors of 168%. O3 Mining has an Outperformer rating. PEA Coming this Quarter Adams presented O3's timeline for Marban Alliance and noted it aligns with CIBC's projections. The next step is completion of a preliminary economic assessment (PEA), slated for Q4/24, "which we expect will be reported on a standalone basis, with upside from potential toll milling agreements," the analyst wrote. G Mining Services now is the lead consultant on the PEA. Next, a feasibility study will be done based on the PEA and the 2022 prefeasibility study. Targeted dates are Q1/25 to start it and Q2/25 to finish it. Also in Q1/25, baseline environmental studies are slated for completion. Impact studies are to be started in Q2/25, and filing is slated for Q1/26. More Strategic Investments O3 Mining completed a non-brokered private placement of CA$1.4 million with Sidex LP and NQ Investissement Minier, two mining investment funds sponsored by the Quebec government, reported Adams. Subsequently, O3 closed a follow-up offering of US$76,800 to the company's strategic investor at the same terms. "We view these as smaller issuances, and after model updates, our net asset value per share estimate is now one penny lower at CA$4.48 per share," Adams wrote. O3 Mining will use the proceeds to drill at Kinebik, where it continues to consolidate land. This project shares the same formation as Hecla Mining Co.'s (HL:NYSE) Casa Berardi mine and Gold Fields Ltd.'s (GFI:NYSE; GFI:JSE) Windfall project. Takeout Target Potential Through its acquisition of Osisko, Gold Fields gained 100% ownership of Windfall (it previously had acquired 50% from Osisko in 2023) and 17% of O3 Mining, Adams pointed out. Gold Fields also unsuccessfully made a bid for Yamana Gold Inc.'s (YRI:TSX; AUY:NYSE; YAU:LSE) interests in the Canadian Malartic mine in Quebec earlier in 2023 and "has indicated further growth interest in Quebec." "With Measured and Indicated resources of 2,400,000 ounces (2.4 Moz) and Inferred resources of 0.6 Moz at its flagship Marban project and near-term final permitting submission, O3 has above average takeout potential," purported Adams. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures: O3 Miing Inc. is a billboard sponsor of Streetwise Reports and pays SWR a monthly sponsorship fee between US$4,000 and US$5,000. Doresa Banning wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an independent contractor. This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. For additional disclosures, please click here. 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( Companies Mentioned: TSXV:OIII;OTCQX:OIIIF, ) Full Article
b Drill Program Targets High-Grade Gold Veins in British Columbia By www.streetwisereports.com Published On :: Wed, 06 Nov 2024 00:00:00 PST Source: Streetwise Reports 11/06/2024 Independence Group NL (IGO:ASX) has begun a comprehensive diamond drill program at its fully-owned 3Ts Project, located in British Columbia.Read more about the 25 planned drill holes aimed at unlocking high-grade intercepts and the promising exploration targets at the 3Ts Project. Independence Gold Corp. (IGO:TSX.V; IEGCF:OTCMKTS) has begun a comprehensive diamond drill program at its fully-owned 3Ts Project, located in British Columbia. Positioned 16 km from Artemis Gold Inc.'s Blackwater Project, the 3Ts Project covers 8,840 hectares within a prolific epithermal quartz-carbonate vein district on the Nechako Plateau. The program will consist of approximately 25 drill holes, totaling a minimum of 7,500 meters. The targets are the Ted-Mint and Tommy Vein Systems, with a primary emphasis on unexplored depth zones to identify high-grade intercepts for mineral resource expansion. The 3Ts Project encompasses multiple identified veins, with strike lengths from 50 to over 1,100 meters and true widths of up to 25 meters. Additional exploration will be directed at the Ian, Johnny, and Larry Veins, focusing on mineralization both along strike and at depth. The Ootsa and Balrog targets, identified through geophysical and geological data collected during the summer 2024 exploration program, are also set to undergo further investigation. President and CEO Randy Turner stated in the press release, "We look forward to building on the success of recent drill programs at 3Ts. With a larger and more extensive drill program planned, including deeper holes to test the major vein systems below the microdiorite sill and further testing of the newly discovered Ootsa and Balrog targets, we anticipate a very busy and exciting year ahead." Upon hearing this news, Jeff Clark of The Gold Advisor wrote, "And they're off! This is the THIRD drill program this year at 3Ts, an aggressive schedule that, as investors, we're very happy to see." He noted that these results will help expand the current resource. He continued, "Remember, management just raised a whopping US$6.65 million, more than double the initial goal, due to strong investor interest. They thus have the financial firepower to conduct all this drilling before winter sets in. The stock isn't reacting to the news, but this isn't something that would normally have a big impact on it. It's cooled from its recent spike so offers a very attractive entry point if you don't have the shares you want. This is an overweight position for me, and it's my belief we'll see more spikes just like the one we witnessed. More news and potential catalysts ahead. This is definitely one to own for the gold bull market." Looking Into Gold On October 29, Kitco reported that gold prices approached US$2,800. This reflects a substantial 35% increase for the year. According to the report, this growth resulted from multiple factors, including geopolitical conflicts, Federal Reserve interest rate normalization, strong central bank demand, and political uncertainties surrounding the upcoming presidential election. Analysts described these elements as a "perfect storm," which significantly bolstered investor sentiment and reinforced gold's appeal as a hedge against economic instability. "This is definitely one to own for the gold bull market," Jeff Clark of The Gold Advisor Wrote. LiveMint, on October 30, noted the strong performance of precious metals, emphasizing that silver had outpaced gold over the past year. Ankit Gohel from LiveMint mentioned, "Gold has delivered a substantial return of over 33.5% since Dhanteras last year," but highlighted that silver had achieved an even more impressive rally of over 40.5%. Despite this, gold continued to attract attention, with Chintan Mehta, CEO of Abans Holdings, emphasizing gold's role as a safe haven during times of uncertainty. He said, "Gold stands out in times of uncertainty . . . It's a complete safe-haven unlike silver, which always has that industrial component attached to it, adding an extra layer of risk." In a November 4 article, Egon von Greyerz of Matterhorn Asset Management provided a historical perspective on gold's consistent role in preserving wealth. Von Greyerz discussed how gold had risen 78 times since 1971, when the dollar lost its gold backing, emphasizing that "gold held in the investor's name in safe vaults and jurisdictions outside the financial system is the ultimate form of wealth preservation." He argued that gold's ascent had only just begun, driven by the devaluation of fiat currencies and ongoing global debt expansion. Independence Catalysts According to the company's September 2024 investor presentation, the 3Ts Project remains a high-priority asset with substantial growth potential. The updated NI 43-101 compliant resource estimate for the Tommy, Ted, and Mint veins, totaling 522,330 ounces of gold and 13.83 million ounces of silver, is expected to expand with new discoveries and continued drilling. Recent metallurgical testing has returned gold recoveries of up to 97.9%, and the strategic location near Artemis Gold's Blackwater Mine adds further credibility to the project's prospects. [OWNERSHIP_CHART-7643] The fall 2024 drill program, with a budget of CA$4.5 million, will test high-grade zones and underexplored targets, building on over 63,000 meters of historical drilling. Additionally, new targets such as the Balrog and Ootsa anomalies present significant exploration upside, underscoring the project's potential for resource expansion and discovery. Ownership and Share Structure According to Refinitiv, about 4.38% of the company is held by insiders and management. 7.97% is with strategic investor Newmont Corp. The rest is retail. Its market cap is CA$29.28 million with 167.8 million shares outstanding. It trades in a 52-week range of CA$0.34 and CA$0.12. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures:1) James Guttman wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an employee. 2) This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. For additional disclosures, please click here. ( Companies Mentioned: IGO:TSX.V;IEGCF:OTCMKTS, ) Full Article
b Visible Gold Brings Continued Excitement to Jr. Explorer's BC Project By www.streetwisereports.com Published On :: Thu, 07 Nov 2024 00:00:00 PST Source: Streetwise Reports 11/07/2024 Drilling and field operations at Golden Cariboo Resources Ltd.'s (GCC:CSE; GCCFF:OTC; A0RLEP:WKN; 3TZ:FSE) past-producing Quesnelle project in British Columbia's Cariboo Gold District continue to find the yellow metal throughout the project, from visible gold in drill cores to mineralization in outcrop samples. One mining analyst says it's a good indication of the mine's potential.Drilling and field operations at Golden Cariboo Resources Ltd.'s (GCC:CSE; GCCFF:OTC; A0RLEP:WKN; 3TZ:FSE) past-producing Quesnelle project in British Columbia's Cariboo Gold District continue to find the yellow metal throughout the project, from visible gold in drill cores to mineralization in outcrop samples. President and Chief Executive Officer Frank Callaghan told Streetwise Reports that despite the high level of experience on his team, several geologists had never seen visible gold before, and their first views of it were "priceless." "It was on the outside of this piece of core," Callaghan said. "And then the core had split … and there was more gold on the inside of it, as well." Callaghan said he's drilled "hundreds and hundreds" of holes, but he "can count on my hands how many times I've seen it (visible gold)." He said the company is seeing the gold in "every drill hole," so they keep moving forward chasing the deposit and working at the site 24 hours a day. And according to Callaghan, the structure of the mineralization is "thickening up" as they drill. The technical team has also recognized multiple types of quartz veins that can contain gold, a common feature in large gold deposits of similar nature. Last month, the company announced it was even forced to stop drilling in a vein zone at the property due to proximity to Osisko Development Corp.'s nearby mineral claims. Drill hole QGQ24-17 was terminated at a depth of 477.32 meters, and the "only thing that stopped us from drilling further was the claim boundary with Osisko," Callaghan said at the time. On Tuesday, the company announced rock sample results from its 2024 field campaign, which found up to 8.47 grams per tonne gold (g/t Au) in one outcrop in the Halo zone and 1.13 g/t Au in another outcrop near the Pioneer showing. "Although there is a lot of glacial cover on this project, our geologists still managed to find new gold-bearing outcrops in areas of great significance," Callaghan said in a release announcing the results. "We have now expanded the surface footprint of gold mineralization at the Halo zone to the northeast and increased the strike length of our gold trend. We're in a very large gold system that is being demonstrated by multiple, varied work programs." Drilling 'Nonstop' and 'Underbudget' Golden Cariboo, a Canadian explorer-developer, is targeting a potential multimillion-ounce gold resource at the 3,814-hectare Quesnelle project, where gold, silver, lead and zinc were produced historically, according to its Investor Presentation. The company's neighbors in the mining district include Osisko's Cariboo Gold Project, Spanish Mountain Gold Ltd. (SPA:TSX.V) (Spanish Mountain deposit), Omineca Mining and Metals Ltd. (OMM:TSX.V; OMMSF:OTCMKTS) (Wingdam mine) and Taseko Mines Ltd. (TKO:TSX; TGB:NYSE.MKT) (Gibraltar mine). Callaghan began rediscovering the Cariboo Camp in the mid-1990s as Barkerville Gold Mines Ltd. He and his then team discovered a gold deposit at Bonanza Ledge and advanced the project to production. He also assembled and developed the Cariboo Gold Project. Ultimately, Osisko Royalties acquired Barkerville and the assets in 2015 for US$338M. Osisko is about to restart mining operations in the camp. Subsequently, in 2019, Callaghan acquired the Quesnelle Gold Quartz project, where he aims to repeat his previous successes, given the property's geology is similar to that of the other two projects. Previously, the company reported observing multiple instances of visible gold in several holes earlier this fall and summer. "Visible gold in current drilling indicates potential for high-grade assays from mineralized targets," Couloir Capital Senior Mining Analyst Ron Wortel wrote in a recent research report. Given that Golden Cariboo is continuing its exploration program at Quesnelle throughout 2024, near-term catalysts include drill and assay results demonstrating significant grades or widths and better-defined mineralization controls and trends, according to Wortel. Callaghan told Streetwise Reports that drilling continues to be "nonstop" and underbudget." External catalysts include market transactions in the junior mining space involving projects or companies in the Cariboo region. Reports by Osisko Development of project advancements or production results relative to adjacent land also could boost Golden Cariboo's stock price. The Catalyst: Index Also Confirms Bull Run for Junior Stocks Experts agreed gold is in a bull market and expect it to go higher. However, after hitting a record high of US$2,790.15 per ounce last week, spot gold was down more than 3% to a three-week low on Wednesday morning as investors moved to the U.S. dollar after Donald Trump's election as U.S. president on Tuesday, Reuters reported. Market participants are also looking ahead to the Federal Reserve's interest rate decision on Thursday for further clues on the bank's easing cycle, Reuters said. "A clear presidential victory when the market has been pricing in a contested result, removal of an element of risk, Trump-trades include the dollar's strengthening this morning and the combination of the two has brought gold lower," StoneX analyst Rhona O'Connell said, according to Reuters. Gold's rise has "resulted in big returns for the investors who bought in earlier this year," Angelica Leicht reported for CBS News last month. "For example, the investors who purchased gold in March when it hit US$2,160 per ounce have seen their gold values increase by nearly 27% in the time since. That's a huge uptick in value in a matter of months, especially on an asset that's known more for long-term growth." Recently polled London Bullion Market Association members indicated they believe the gold price could reach US$2,940/oz during 2025, reported Stockhead on Oct. 28.[OWNERSHIP_CHART-11131] "Combined with expectations of lower global interest rates, this further enhances gold's attractiveness as an investment," the article noted. As for gold equities, the S&P/TSX Venture Composite Index (SPCDNX) confirmed a bull run for junior, intermediate, and senior mining stocks when it closed above 1,000 recently, Stewart Thomson with 321Gold wrote. The index is a key indicator of the health of the general gold, silver, and mining stocks market. Ownership and Share Structure According to Golden Cariboo, management and insiders own 30% of Golden Cariboo Resources. President and CEO Frank Callaghan owns 16.45% or 6.93 million shares; Elaine Callaghan has 0.97% or 0.41 million shares; Director Andrew Rees has 0.79% or 0.33 million shares; and Director Laurence Smoliak has 0.3% or 0.13 million shares. Retail investors hold the remaining. There are no institutional investors. The company said it has 50.3 million shares outstanding, 24.83 million warrants, and 3.8 million options. Its market cap is CA$9.63 million. Over the past 52 weeks, Golden Cariboo has traded between CA$0.08 and CA$0.36 per share. Sign up for our FREE newsletter at: www.streetwisereports.com/get-newsImportant Disclosures: Omineca Mining and Metals Ltd. is a billboard sponsor of Streetwise Reports and pays SWR a monthly sponsorship fee between US$4,000 and US$5,000. Golden Cariboo Resources Ltd. has a consulting relationship with Street Smart an affiliate of Streetwise Reports. Street Smart Clients pay a monthly consulting fee between US$8,000 and US$20,000. As of the date of this article, officers and/or employees of Streetwise Reports LLC (including members of their household) own securities of Golden Cariboo Resources Ltd. and Omineca Mining and Metals Ltd. Steve Sobek wrote this article for Streetwise Reports LLC and provides services to Streetwise Reports as an employee. This article does not constitute investment advice and is not a solicitation for any investment. Streetwise Reports does not render general or specific investment advice and the information on Streetwise Reports should not be considered a recommendation to buy or sell any security. Each reader is encouraged to consult with his or her personal financial adviser and perform their own comprehensive investment research. By opening this page, each reader accepts and agrees to Streetwise Reports' terms of use and full legal disclaimer. Streetwise Reports does not endorse or recommend the business, products, services or securities of any company. For additional disclosures, please click here. ( Companies Mentioned: GCC:CSE; GCCFF:OTC; A0RLEP:WKN;3TZ:FSE, ) Full Article
b Gay And Bisexual Men Are Now Allowed To Donate Blood In England, Scotland And Wales By www.scpr.org Published On :: Wed, 16 Jun 2021 02:20:11 -0700 Gay and bisexual men in England, Scotland, and Wales can now donate blood, plasma and platelets under certain circumstances without having to wait three months, the National Health Service announced this week.; Credit: Wilfredo Lee/AP Jaclyn Diaz | NPRGay and bisexual men in England, Scotland, and Wales can now donate blood, plasma and platelets under certain circumstances, the National Health Service announced this week in a momentous shift in policy for most of the U.K. Beginning Monday, gay men in sexually active, monogamous relationships for at least three months can donate for the first time. The move reverses a policy that limited donor eligibility on perceived risks of contracting HIV/AIDs and other sexually transmitted infections. The new rules come as the U.K. and other countries around the world report urgent, pandemic-induced blood supply issues. Donor eligibility will now be based on each person's individual circumstances surrounding health, travel and sexual behaviors regardless of gender, according to the NHS. Potential donors will no longer be asked if they are a man who has had sex with another man, but they will be asked about recent sexual activity. Anyone who has had the same sexual partner for the last three months can donate, the NHS said. "Patient safety is at the heart of everything we do. This change is about switching around how we assess the risk of exposure to a sexual infection, so it is more tailored to the individual," said Ella Poppitt, Chief Nurse for blood donation at NHS Blood and Transplant, in a statement. "We screen all donations for evidence of significant infections, which goes hand-in-hand with donor selection to maintain the safety of blood sent to hospitals." People who engage in anal sex with a new partner or multiple people or who have recently used PrEP or PEP (medication used to prevent HIV infection) will have to wait three months to donate - regardless of their gender. Why did the U.K. make this change? The NHS moved to alter its blood donation eligibility rules following a review by the FAIR (For the Assessment of Individualised Risk) steering group. The panel determined an individualized, gender-neutral approach to determining who can donate blood, platelets, and plasma is fairer and still maintains the safety of the U.K.'s blood supply. The findings were accepted in full by the government last December. Researchers will continue to monitor the impact of the donor selection changes for the next 12 months to determine if more changes are needed, NHS said. What is the policy in the U.S.? Despite efforts by advocates to change regulations in the U.S, the ability for gay and bisexual men to donate blood is still restricted. A ban on gay and bisexual blood donors has been in effect since the early 1980s when fears about HIV/AIDS were widespread. The Food and Drug Administration's current policy states a man who has sex with another man in the previous three months can't donate. Federal rules previously made such donors wait 12 months before giving blood, but due to low blood supplies during the pandemic the federal government changed the policy in April. The Red Cross said they are participating in a pilot study funded by the FDA using behavior-based health history questionnaires, similar to those used in the U.K. Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b To Keep Your Brain Young, Take Some Tips From Our Earliest Ancestors By www.scpr.org Published On :: Fri, 18 Jun 2021 04:00:06 -0700 Reconstructions from the Daynès Studio in Paris depict a male Neanderthal (right) face to face with a human, Homo sapiens.; Credit: /Science Source Bret Stetka | NPRIt's something that many of us reckon with: the sense that we're not quite as sharp as we once were. I recently turned 42. Having lost my grandfather to Alzheimer's, and with my mom suffering from a similar neurodegenerative disease, I'm very aware of what pathologies might lurk beneath my cranium. In the absence of a cure for Alzheimer's and other forms of dementia, the most important interventions for upholding brain function are preventive — those that help maintain our most marvelous, mysterious organ. Based on the science, I take fish oil and broil salmon. I exercise. I try to challenge my cortex to the unfamiliar. As I wrote my recent book, A History of the Human Brain, which recounts the evolutionary tale of how our brain got here, I began to realize that so many of the same influences that shaped our brain evolution in the first place reflect the very measures we use to preserve our cognitive function today. Being social, and highly communicative. Exploring creative pursuits. Eating a varied, omnivorous diet low in processed foods. Being physically active. These traits and behaviors help retrace our past, and, I believe, were instrumental in why we remain on the planet today. And they all were, at least in part, enabled by our brain. Social smart alecks finish first The human saga is riddled with extinctions. By "human," I don't just mean Homo sapiens, the species we belong to, but any member of the genus Homo. We've gotten used to being the only human species on Earth, but in our not so distant past — probably a few hundred thousand years ago – there were at least nine of us running around. There was Homo habilis, or the "handy man." And Homo erectus, the first "pitcher." The Denisovans roamed Asia, while the more well-known Neanderthals spread throughout Europe. But with the exception of Homo sapiens, they're all gone. And there's a good chance it was our fault. Humans were never the fastest lot on the African plains, and far from the strongest. Cheetahs, leopards and lions held those distinctions. In our lineage, natural selection instead favored wits and wiliness. Plenty of us became cat food, but those with a slight cognitive edge — especially Homo sapiens — lived on. In our ilk, smarts overcame strength and speed in enabling survival. Ecology, climate, location and just sheer luck would've played important roles in who persisted or perished as well, as they do for most living beings. But the evolutionary pressure for more complex mental abilities would lead to a massive expansion in our brain's size and neurocircuitry that is surely the paramount reason we dominate the planet like no other species ever has. Much of this "success," if you can call it that, was due to our social lives. Primates are communal creatures. Our close monkey and ape cousins are incredibly interactive, grooming each other for hours a day to maintain bonds and relationships. Throw in a few hoots and hollers and you have a pretty complex community of communicating simians. An active social life is now a known preserver of brain function. Research shows that social isolation worsens cognitive decline (not to mention mental health, as many of us experienced this past year). Larger social networks and regular social activities are associated with mental preservation and slowed dementia progression. Entwined in this new social life was an evolutionary pressure that favored innovation. Our eventual ability to generate completely novel thoughts and ideas, and to share those ideas, came to define our genus. As we hunted and foraged together, and honed stones into hand axes, there was a collective creativity at work that gave us better weapons and tools that enabled more effective food sourcing, and, later, butchering and fire. Effectively sharing these innovations with our peers allowed information to spread faster than ever before - a seed for the larger communities and civilizations to come. Challenging ourselves to new pursuits and mastering new skills can not only impress peers and ingratiate us to our group, but literally help preserve our brain. New hobbies. New conversations. Learning the banjo. Even playing certain video games and simply driving a new route home from work each day, as neuroscientist David Eagleman does, can keep our function high. Whether it's honing ancient stone or taking up Sudoku, any pursuit novel and mentally challenging may help keep the neural circuits firing. We really are what we eat All the while, as we hunted and crafted in new and communal ways, we had to eat. And we did so with an uniquely adventurous palette. Homo sapiens is among the most omnivorous species on the planet. Within reason we eat just about anything. Whether it's leaves, meat, fungus, or fruit, we don't discriminate. At some point, one of us even thought it might be a good idea to try the glistening, grey blobs that are oysters - and shellfish are, it turns out, among the healthiest foods for our brain. The varied human diet is an integral part of our story. As was the near constant physicality required to source it. On multiple occasions over the past 1 to 2 million years climate changes dried out the African landscape, forcing our ancestors out of the lush forest onto the dangerous, wide-open grasslands. As evolution pressured us to create and commune to help us survive, a diverse diet also supported our eventual global takeover. Our arboreal past left us forever craving the dangling fruits of the forest, a supreme source of high-calorie sugars that ensured survival. Back then we didn't live long enough to suffer from Type 2 diabetes: if you encountered sweets, you ate them. And today we're stuck with a taste for cookies and candy that, given our longer lifespans, can take its toll on the body and brain. But humans were just as amenable to dining on the bulbs, rhizomes and tubers of the savanna, especially once fire came along. We eventually became adept scavengers of meat and marrow, the spoils left behind by the big cats, who preferred more nutritive organ meat. As our whittling improved we developed spears, and learned to trap and hunt the beasts of the plains ourselves. There is also evidence that we learned to access shellfish beds along the African coast and incorporate brain-healthy seafood into our diet. Studying the health effects of the modern diet is tricky. Dietary studies are notoriously dubious, and often involve countless lifestyle variables that are hard to untangle. Take blueberries. Multiple studies have linked their consumption with improved brain health. But, presumably, the berry-prone among us are also more likely to eat healthy all around, exercise, and make it to level 5 on their meditation app. Which is why so many researchers, nutritionists, and nutritional psychiatrists now focus on dietary patterns, like those akin to Mediterranean culinary customs, rather than specific ingredients. Adhering to a Mediterranean diet is linked with preserved cognition; and multiple randomized-controlled trials suggest doing so can lower depression risk. A similar diversity in our ancestral diet helped early humans endure an ever-shifting climate and times of scarcity. We evolved to subsist and thrive on a wide range of foods, in part because our clever brains allowed us access to them. In turn, a similarly-varied diet (minus submitting to our innate sugar craving of course) is among the best strategies to maintain brain health. All of our hunting, and foraging, and running away from predators would have required intense physical exertion. This was certainly not unique to humans, but we can't ignore the fact that regular exercise is another effective means of preserving brain health. Being active improves performance on mental tasks, and may help us better form memories. Long before the Peletons sold out, our brains relied on both mental and physical activity. But overwhelmingly the evidence points to embracing a collection of lifestyle factors to keep our brain healthy, none of which existed in a Darwinian vacuum. Finding food was as social an endeavor as it was mental and physical. Our creative brains harnessed information; gossiping, innovating, and cooking our spoils around the campfire. Researchers are beginning to piece together the complex pathology behind the inevitable decline of the human brain, and despite a parade of failed clinical trials in dementia, there should be promising treatments ahead. Until then, in thinking about preserving the conscious experience of our world and relationships — and living our longest, happiest lives — look to our past. Bret Stetka is a writer based in New York and an editorial director at Medscape. His work has appeared in Wired, Scientific American, and on The Atlantic.com. His new book, A History of the Human Brain, is out from Timber/Workman Press. He's also on Twitter: @BretStetka. Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b Biden's Broader Vision For Medicaid Could Include Inmates, Immigrants, New Mothers By www.scpr.org Published On :: Wed, 23 Jun 2021 09:20:09 -0700 Chiquita Brooks-LaSure, administrator of the Centers for Medicare & Medicaid Services, leads some of the Biden administration's efforts to expand Medicaid access.; Credit: Caroline Brehman/CQ-Roll Call, Inc via Getty Imag Noam N. Levey and Phil Galewitz | NPRThe Biden administration is quietly engineering a series of expansions to Medicaid that may bolster protections for millions of low-income Americans and bring more people into the program. Biden's efforts — which have been largely overshadowed by other economic and health initiatives — represent an abrupt reversal of the Trump administration's moves to scale back the safety-net program. The changes could further boost Medicaid enrollment — which the pandemic has already pushed to a record 80.5 million. Some of the expansion is funded by the COVID-19 relief bill that passed in March, including coverage for new mothers. Others who could also gain coverage under Biden are inmates and undocumented immigrants. At the same time, the administration is opening the door to new Medicaid-funded services such as food and housing that the government insurance plan hasn't traditionally offered. "There is a paradigm change underway," said Jennifer Langer Jacobs, Medicaid director in New Jersey, one of a growing number of states trying to expand home-based Medicaid services to keep enrollees out of nursing homes and other institutions. "We've had discussions at the federal level in the last 90 days that are completely different from where we've ever been before," Langer Jacobs said. Taken together, the Medicaid moves represent some of the most substantive shifts in federal health policy undertaken by the new administration. "They are taking very bold action," said Rutgers University political scientist Frank Thompson, an expert on Medicaid history, noting in particular the administration's swift reversal of Trump policies. "There really isn't a precedent." The Biden administration seems unlikely to achieve what remains the holy grail for Medicaid advocates: getting 12 holdout states, including Texas and Florida, to expand Medicaid coverage to low-income working-age adults through the Affordable Care Act. And while some of the recent expansions – including for new mothers -- were funded by close to $20 billion in new Medicaid funding in the COVID relief bill Biden signed in March, much of that new money will stop in a few years unless Congress appropriates additional money. The White House strategy has risks. Medicaid, which swelled after enactment of the 2010 health law, has expanded further during the economic downturn caused by the pandemic, pushing enrollment to a record 80.5 million, including those served by the related Children's Health Insurance Program. That's up from 70 million before the COVID crisis began. The programs now cost taxpayers more than $600 billion a year. And although the federal government will cover most of the cost of the Biden-backed expansions, surging Medicaid spending is a growing burden on state budgets. The costs of expansion are a frequent target of conservative critics, including Trump officials like Seema Verma, the former administrator of the Centers for Medicare & Medicaid Services, who frequently argued for enrollment restrictions and derided Medicaid as low-quality coverage. But even less partisan experts warn that Medicaid, which was created to provide medical care to low-income Americans, can't make up for all the inadequacies in government housing, food and education programs. "Focusing on the social drivers of health ... is critically important in improving the health and well-being of Medicaid beneficiaries. But that doesn't mean that Medicaid can or should be responsible for paying for all of those services," said Matt Salo, head of the National Association of Medicaid Directors, noting that the program's financing "is simply not capable of sustaining those investments." Restoring federal support However, after four years of Trump administration efforts to scale back coverage, Biden and his appointees appear intent on not only restoring federal support for Medicaid, but also boosting the program's reach. "I think what we learned during the repeal-and-replace debate is just how much people in this country care about the Medicaid program and how it's a lifeline to millions," Biden's new Medicare and Medicaid administrator, Chiquita Brooks-LaSure, told KHN, calling the program a "backbone to our country." The Biden administration has already withdrawn permission the Trump administration had granted Arkansas and New Hampshire to place work requirements on some Medicaid enrollees. In April, Biden blocked a multibillion-dollar Trump administration initiative to prop up Texas hospitals that care for uninsured patients, a policy that many critics said effectively discouraged Texas from expanding Medicaid coverage through the Affordable Care Act, often called Obamacare. Texas has the highest uninsured rate in the nation. The moves have drawn criticism from Republicans, some of whom accuse the new administration of trampling states' rights to run their Medicaid programs as they choose. "Biden is reasserting a larger federal role and not deferring to states," said Josh Archambault, a senior fellow at the conservative Foundation for Government Accountability. But Biden's early initiatives have been widely hailed by patient advocates, public health experts and state officials in many blue states. "It's a breath of fresh air," said Kim Bimestefer, head of Colorado's Department of Health Care Policy and Financing. Chuck Ingoglia, head of the National Council for Mental Wellbeing, said: "To be in an environment where people are talking about expanding health care access has made an enormous difference." Mounting evidence shows that expanded Medicaid coverage improves enrollees' health, as surveys and mortality data in recent years have identified greater health improvements in states that expanded Medicaid through the 2010 health law versus states that did not. Broadening eligibility In addition to removing Medicaid restrictions imposed by Trump administration officials, the Biden administration has backed a series of expansions to broaden eligibility and add services enrollees can receive. Biden supported a provision in the COVID relief bill that gives states the option to extend Medicaid to new mothers for up to a year after they give birth. Many experts say such coverage could help reduce the U.S. maternal mortality rate, which is far higher than rates in other wealthy nations. Several states, including Illinois and New Jersey, had sought permission from the Trump administration for such expanded coverage, but their requests languished. The COVID relief bill — which passed without Republican support — also provides additional Medicaid money to states to set up mobile crisis services for people facing mental health or substance use emergencies, further broadening Medicaid's reach. And states will get billions more to expand so-called home and community-based services such as help with cooking, bathing and other basic activities that can prevent Medicaid enrollees from having to be admitted to expensive nursing homes or other institutions. Perhaps the most far-reaching Medicaid expansions being considered by the Biden administration would push the government health plan into covering services not traditionally considered health care, such as housing. This reflects an emerging consensus among health policy experts that investments in some non-medical services can ultimately save Medicaid money by keeping patients out of the hospital. In recent years, Medicaid officials in red and blue states — including Arizona, California, Illinois, Maryland and Washington — have begun exploring ways to provide rental assistance to select Medicaid enrollees to prevent medical complications linked to homelessness. The Trump administration took steps to support similar efforts, clearing Medicare Advantage health plans to offer some enrollees non-medical benefits such as food, housing aid and assistance with utilities. But state officials across the country said the new administration has signaled more support for both expanding current home-based services and adding new ones. That has made a big difference, said Kate McEvoy, who directs Connecticut's Medicaid program. "There was a lot of discussion in the Trump administration," she said, "but not the capital to do it." Other states are looking to the new administration to back efforts to expand Medicaid to inmates with mental health conditions and drug addiction so they can connect more easily to treatment once released. Kentucky health secretary Eric Friedlander said he is hopeful federal officials will sign off on his state's initiative. Still other states, such as California, say they are getting a more receptive audience in Washington for proposals to expand coverage to immigrants who are in the country without authorization, a step public health experts say can help improve community health and slow the spread of communicable diseases. "Covering all Californians is critical to our mission," said Jacey Cooper, director of California's Medicaid program, known as Medi-Cal. "We really feel like the new administration is helping us ensure that everyone has access." The Trump administration moved to restrict even authorized immigrants' access to the health care safety net, including the "public charge" rule that allowed immigration authorities to deny green cards to applicants if they used public programs such as Medicaid. In March, Biden abandoned that rule. KHN correspondent Julie Rovner contributed to this report. KHN (Kaiser Health News) is a national newsroom that produces in-depth journalism about health issues. Together with Policy Analysis and Polling, KHN is one of the three major operating programs at KFF (Kaiser Family Foundation). KFF is an endowed nonprofit organization providing information on health issues to the nation. Copyright 2021 Kaiser Health News. To see more, visit Kaiser Health News. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b The Pandemic Led To The Biggest Drop In U.S. Life Expectancy Since WWII, Study Finds By www.scpr.org Published On :: Wed, 23 Jun 2021 17:40:11 -0700 A COVID-19 vaccination clinic last month in Auburn, Maine. A drop in life expectancy in the U.S. stems largely from the coronavirus pandemic, a new study says.; Credit: Robert F. Bukaty/AP Allison Aubrey | NPRA new study estimates that life expectancy in the U.S. decreased by nearly two years between 2018 and 2020, largely due to the COVID-19 pandemic. And the declines were most pronounced among minority groups, including Black and Hispanic people. In 2018, average life expectancy in the U.S. was about 79 years (78.7). It declined to about 77 years (76.9) by the end of 2020, according to a new study published in the British Medical Journal. "We have not seen a decrease like this since World War II. It's a horrific decrease in life expectancy," said Steven Woolf of the Virginia Commonwealth University School of Medicine and an author of the study released on Wednesday. (The study is based on data from the National Center for Health Statistics and includes simulated estimates for 2020.) Beyond the more than 600,000 deaths in the U.S. directly from the coronavirus, other factors play into the decreased longevity, including "disruptions in health care, disruptions in chronic disease management, and behavioral health crisis, where people struggling with addiction disorders or depression might not have gotten the help that they needed," Woolf said. The lack of access to care and other pandemic-related disruptions hit some Americans much harder than others. And it's been well documented that the death rate for Black Americans was twice as high compared with white Americans. The disparity is reflected in the new longevity estimates. "African Americans saw their life expectancy decrease by 3.3 years and Hispanic Americans saw their life expectancy decrease by 3.9 years," Woolf noted. "These are massive numbers," Woolf said, that reflect the systemic inequalities that long predate the pandemic. "It is impossible to look at these findings and not see a reflection of the systemic racism in the U.S.," Lesley Curtis, chair of the Department of Population Health Sciences at Duke University School of Medicine, told NPR. "This study further destroys the myth that the United States is the healthiest place in the world to live," Dr. Richard Besser, president of the Robert Wood Johnson Foundation (an NPR funder), said in an email. He said wide differences in life expectancy rates were evident before COVID-19. "For example, life expectancy in Princeton, NJ—a predominantly White community—is 14 years higher than Trenton, NJ, a predominantly Black and Latino city only 14 miles away," Besser said. Life expectancy in the U.S. had already been declining — albeit slowly — in the years leading up to the pandemic. And the U.S. has been losing ground compared with other wealthy countries, said Magali Barbieri of the University of California, Berkeley, in an editorial published alongside the new study. The study estimates that the decline in life expectancy was .22 years (or about one-fifth of a year) in a group of 16 peer countries (including Austria, Finland, France, Israel, the Netherlands and the United Kingdom) compared with the nearly two-year decline in the United States. "The U.S. disadvantage in mortality compared with other high income democracies in 2020 is neither new nor sudden," Barbieri wrote. It appears the pandemic has magnified existing vulnerabilities in U.S. society, she added. "The range of factors that play into this include income inequality, the social safety net, as well as racial inequality and access to health care," Duke's Curtis said. So, what's the prognosis going forward in the United States? "I think life expectancy will rebound," Woolf of Virginia Commonwealth said. But it's unlikely that the U.S. is on course to reverse the trend entirely. "The U.S. has some of the best hospitals and some of the greatest scientists. But other countries do far better in getting quality medical care to their population," Woolf said. "We have big gaps in getting care to people who need it most, when they need it most." Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b He Inherited A Devastating Disease. A CRISPR Gene-Editing Breakthrough Stopped It By www.scpr.org Published On :: Sat, 26 Jun 2021 10:20:08 -0700 Patrick Doherty volunteered for a new medical intervention of gene-editor infusions for the treatment of genetically-based diseases.; Credit: /Patrick Doherty Rob Stein | NPRPatrick Doherty had always been very active. He trekked the Himalayas and hiked trails in Spain. But about a year and a half ago, he noticed pins and needles in his fingers and toes. His feet got cold. And then he started getting out of breath any time he walked his dog up the hills of County Donegal in Ireland where he lives. "I noticed on some of the larger hill climbs I was getting a bit breathless," says Doherty, 65. "So I realized something was wrong." Doherty found out he had a rare, but devastating inherited disease — known as transthyretin amyloidosis — that had killed his father. A misshapen protein was building up in his body, destroying important tissues, such as nerves in his hands and feet and his heart. Doherty had watched others get crippled and die difficult deaths from amyloidosis. "It's terrible prognosis," Doherty says. "This is a condition that deteriorates very rapidly. It's just dreadful." So Doherty was thrilled when he found out that doctors were testing a new way to try to treat amyloidosis. The approach used a revolutionary gene-editing technique called CRISPR, which allows scientists to make very precise changes in DNA. "I thought: Fantastic. I jumped at the opportunity," Doherty says. On Saturday, researchers reported the first data indicating that the experimental treatment worked, causing levels of the destructive protein to plummet in Doherty's body and the bodies of five other patients treated with the approach. "I feel fantastic," Doherty says. "It's just phenomenal." The advance is being hailed not just for amyloidosis patients but also as a proof-of-concept that CRISPR could be used to treat many other, much more common diseases. It's a new way of using the innovative technology. "This is a major milestone for patients," says Jennifer Doudna of the University of California, Berkeley, who shared a Nobel Prize for her work helping develop CRISPR. "While these are early data, they show us that we can overcome one of the biggest challenges with applying CRISPR clinically so far, which is being able to deliver it systemically and get it to the right place," Doudna says. CRISPR has already been shown to help patients suffering from the devastating blood disorders sickle cell disease and beta thalassemia. And doctors are trying to use it to treat cancer and to restore vision to people blinded by a rare genetic disorder. But those experiments involve taking cells out of the body, editing them in the lab, and infusing them back in or injecting CRISPR directly into cells that need fixing. The study Doherty volunteered for is the first in which doctors are simply infusing the gene-editor directly into patients and letting it find its own way to the right gene in the right cells. In this case, it's cells in the liver making the destructive protein. "This is the first example in which CRISPR-Cas9 is injected directly into the bloodstream — in other words systemic administration — where we use it as a way to reach a tissue that's far away from the site of injection and very specifically use it to edit disease-causing genes," says John Leonard, the CEO of Intellia Therapeutics, which is sponsoring the study. Doctors infused billions of microscopic structures known as nanoparticles carrying genetic instructions for the CRISPR gene-editor into four patients in London and two in New Zealand. The nanoparticles were absorbed by their livers, where they unleashed armies of CRISPR gene-editors. The CRISPR editor honed in on the target gene in the liver and sliced it, disabling production of the destructive protein. Within weeks, the levels of protein causing the disease plummeted. Researchers reported at the Peripheral Nerve Society Annual Meeting and in a paper published in The New England Journal of Medicine. "It really is exciting," says Dr. Julian Gillmore, who is leading the study at the University College London, Royal Free Hospital. "This has the potential to completely revolutionize the outcome for these patients who have lived with this disease in their family for many generations. It's decimated some families that I've been looking after. So this is amazing," Gillmore says. The patients will have to be followed longer, and more patients will have to be treated, to make sure the treatment's safe, and determine how much it's helping, Gillmore stresses. But the approach could help those struck by amyloidosis that isn't inherited, which is a far more common version of the disease, he says. Moreover, the promising results potentially open the door for using the same approach to treatment of many other, more common diseases for which taking cells out of the body or directly injecting CRISPR isn't realistic, including heart disease, muscular dystrophy and brain diseases such as Alzheimer's. "This is really opening a new era as we think about gene-editing where we can begin to think about accessing all kinds of different tissue in the body via systemic administration," Leonard says. Other scientists who are not involved in the research agree. "This is a wonderful day for the future of gene-editing as a medicine," agree Fyodor Urnov, a professor of genetics at the University of California, Berkeley. "We as a species are watching this remarkable new show called: our gene-edited future." Doherty says he started feeling better within weeks of the treatment and has continued to improve in the weeks since then. "I definitely feel better," he told NPR. "I'm speaking to you from upstairs in our house. I climbed stairs to get up here. I would have been feeling breathless. I'm thrilled." Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b 12 Holdout States Haven't Expanded Medicaid, Leaving 2 Million People In Limbo By www.scpr.org Published On :: Thu, 01 Jul 2021 04:00:13 -0700 Advocates for expanding Medicaid in Kansas staged a protest outside the entrance to the statehouse parking garage in Topeka in May 2019. Today, twelve states have still not expanded Medicaid. The biggest are Texas, Florida, and Georgia, but there are a few outside the South, including Wyoming and Kansas.; Credit: John Hanna/AP Selena Simmons-Duffin | NPRThere are more than 2 million people across the United States who have no option when it comes to health insurance. They're in what's known as the "coverage gap" — they don't qualify for Medicaid in their state, and make too little money to be eligible for subsidized health plans on the Affordable Care Act insurance exchanges. Briana Wright is one of those people. She's 27, lives near Jackson, Miss., works at McDonalds, and doesn't have health insurance. So to figure out her options when she recently learned she needed to have surgery to remove her gallbladder, she called Health Help Mississippi, a nonprofit that helps people enroll in health insurances. Because she lives in Mississippi, "I wasn't going to be eligible for Medicaid — because I don't have children [and] I'm not pregnant," she tells NPR. When she had her income checked for Healthcare.gov, it was just shy of the federal poverty line — the minimum to qualify for subsidies. "It was $74 [short]. I was like, oh wow," she says. Wright's inability to get a subsidized policy on Healthcare.gov is related to how the Affordable Care Act was originally designed. People needing insurance who were above the poverty line were supposed to be funneled via the federal and state insurance exchanges to private policies — with federal subsidies to help make those policies affordable. People who were under the poverty line were to be funneled to a newly-expanded version of Medicaid — the public health insurance program that is jointly funded by states and the federal government. But the Supreme Court made Medicaid expansion essentially optional in 2012, and many Republican-led states declined to expand. Today, there are 12 holdout states that have not expanded Medicaid, and Mississippi is one of them. So, Wright is still uninsured. Her gallbladder is causing her pain, but she can't afford the surgery without shuffling household bills, and risking leaving something else unpaid. "I'm stressed out about it. I don't know what I'm going to do," she says. "I'm going to just have to pay it out of pocket or get on some payment plan until it all gets paid for." Hoping to finally find a fix for Wright and the millions like her who are in Medicaid limbo, several teams of Democratic lawmakers have recently been hashing out several options — hoping to build on the momentum of the latest Supreme Court confirmation that the ACA is here to stay. OPTION 1: Sweet-talk the 12 holdout states The COVID-19 relief bill passed in March included financial enticements for these 12 states to expand Medicaid. Essentially, the federal government will cover 90% of the costs of the newly eligible population, and an additional 5% of the costs of those already enrolled. It's a good financial deal. An analysis by the nonprofit Kaiser Family Foundation estimates that the net benefit for these states would be $9.6 billion. But, so far — publicly, at least — no states have indicated they intend to take the federal government up on its offer. "If that is not getting states to move, then that suggests that the deep root of their hesitation is not about financial constraint," says Jamila Michener, a professor of government at Cornell University and author of the book Fragmented Democracy: Medicaid Federalism And Unequal Politics. Instead, Michener says, the reluctance among some Republican-led legislatures and governors to expand Medicaid may be a combination of partisan resistance to President Obama's signature health law, and not believing "this kind of government intervention for these groups of people is appropriate." What's Next: When asked about progress on this front in an April press briefing, Biden's press secretary Jen Psaki said "the President is certainly supportive of — and an advocate for — states expanding Medicaid," but did not answer a follow up about whether the White House was directly reaching out to governors regarding this option. OPTION 2: Create a federal public option to fill the gap Some have advocated for circumventing these holdout states and creating a new, standalone federal Medicaid program that people who fall into this coverage gap could join. It would be kind of like a tailored public option just for this group. This idea was included in Biden's 2022 budget, which says, in part: "In States that have not expanded Medicaid, the President has proposed extending coverage to millions of people by providing premium-free, Medicaid-like coverage through a Federal public option, paired with financial incentives to ensure States maintain their existing expansions." But it wouldn't be simple. "That can be quite complex — to implement a federal program that's targeted to just these 2.2 million people across a handful of states," says Robin Rudowitz, co-director of the Medicaid program at the Kaiser Family Foundation, who wrote a recent analysis of the policy options. It also may be a heavy lift, politically, says Michener. "Anything that expanded the footprint of the federal government and its role in subsidizing health care would be especially challenging," she says. What's next: This idea was raised as a possible solution in a letter last month from Georgia's Democratic senators to Senate leaders, and Sen. Raphael Warnock said this week he plans to introduce legislation soon. OPTION 3: Get around stubborn states by letting cities expand Medicaid Instead of centralizing the approach, this next idea goes even more local. The COVER Now Act, introduced by Rep. Lloyd Doggett, D-Texas, would empower local jurisdictions to expand Medicaid. So, if you live in Austin, Texas, maybe you could get Medicaid, even if someone in Lubbock still couldn't. The political and logistical challenges would be tough, policy analysts say. Logistically, such a plan would require counties and cities to create new infrastructure to run a Medicaid program, Rudowitz notes, and the federal government would have to oversee how well these new local programs complied with all of Medicaid's rules. "It does not seem feasible politically," Michener says. "The legislators who would have to vote to make this possible would be ceding quite a bit of power to localities." It also might amplify geographic equity concerns, she says. People's access to health insurance would not just "be arbitrarily based on what state you live in — which is the current state of affairs — It's also going to be arbitrary based on what county you live in, based on what city you live in." What's next: Doggett introduced the bill earlier this month. There's no guarantee it would get a vote on the House floor and — even if it did — it wouldn't survive a likely filibuster in the evenly divided Senate. OPTION 4: Change the ACA to open up the exchanges A fourth idea, Rudowitz says, is to change the law to remove the minimum cutoff for the private health insurance exchanges, since "right now, individuals who are below poverty are not eligible for subsidies in the marketplace." With this option, states wouldn't be paying any of the costs, since the federal government pays premium subsidies, Rudowitz says, but "there are issues around beneficiary protections, benefits, out-of-pocket costs." What's next: This idea hasn't yet been included in any current congressional bills. Will any of these ideas come to fruition? Even with a variety of ideas on the table, "there's no slam dunk option, it's a tough policy issue," Rudowitz says. All of these would be complicated to pull off. It's possible Democrats will include one of these ideas in a reconciliation bill that could pass without the threat of a Republican filibuster. But that bill has yet to be written, and what will be included is anyone's guess. Even so, Michener says she's glad the discussion of the Medicaid coverage gap is happening, because it's sensitizing the public, as well as people in power, to the problem and potentially changing the political dynamic down the line. "Even in policy areas where you don't have any kind of guaranteed victory, it is often worth fighting the fight," she says. "Politics is a long game." Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b How And Why Was Bill Cosby’s Sex Assault Conviction Overturned? By www.scpr.org Published On :: Wed, 30 Jun 2021 10:52:59 -0700 Bill Cosby exits the Montgomery County Courthouse in Norristown, Pa., Saturday, June 17, 2017. ; Credit: Matt Rourke/AP AirTalkPennsylvania’s highest court overturned. Bill Cosby’s sex assault conviction Wednesday after finding an agreement with a previous prosecutor prevented him from being charged in the case. Cosby has served more than two years of a three- to 10-year sentence at a state prison near Philadelphia. He had vowed to serve all 10 years rather than acknowledge any remorse over the 2004 encounter with accuser Andrea Constand. We dive into how this all happened, through the lens of law, celebrity and the MeToo movement. With files from the Associated Press Guests: Ambrosio Rodriguez, former prosecutor; he is currently a criminal defense attorney at The Rodriguez Law Group in Los Angeles; he led the sex crimes team and was in the homicide unit in the Riverside D.A.’s office; he tweets at @aer_attorney Laurie L. Levenson, professor of criminal law at Loyola Law School in Los Angeles and former federal prosecutor This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
b The Supreme Court’s Final Rulings Of The Spring 2021 Term, Plus A Retrospective On Some Of Its Biggest Cases By www.scpr.org Published On :: Thu, 01 Jul 2021 09:07:38 -0700 The US Supreme Court is seen in Washington, DC on July 1, 2021.; Credit: MANDEL NGAN/AFP via Getty Images AirTalkThe U.S. Supreme Court ends its spring term today with two final decisions expected to come down, one involving a pivotal voting rights case out of Arizona and the other involving so-called “dark money” and campaign finance. Today on AirTalk, we’ll get a summary of the arguments that each side in the two cases will be making, and we’ll look back on the Spring 2021 term overall, as the nine justices will break until the fall. Guests: Vikram Amar, dean and professor of law at the University of Illinois College of Law David Becker, executive director and founder of the Center for Election Innovation and Research, a nonpartisan, non-profit organization that works with election officials around the country to ensure convenient and secure voting for all voters; he is the former director of the elections program at The Pew Charitable Trusts and a former senior trial attorney in the Voting Section of the Department of Justice’s Civil Rights Division; he tweets @beckerdavidj This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article