There is provided a method for producing an aqueous acrylamide solution by reacting a composition including acrylonitrile with water to produce acrylamide, in which the composition including acrylonitrile includes 3 to 15 mg of propionitrile per 1 kg of the total weight of the composition including acrylonitrile. According to the present invention, a production method with which it is possible to suppress acrylamide polymerization without lowering quality and thereby obtain a stable aqueous acrylamide solution can be provided.

The esterfication of hypophosphorous acid is followed by reaction with another molecule of alcohol under the action of a nickel catalyst to provide a green method for the preparation of H-phosphonate diesters. This method avoids the need for any stoichiometric chlorine unlike those based on phosphorous trichloride.

Aromatic N-halosulfonamide organic compounds have been known for over one hundred years. The ability of these compounds to release active halogen ions has been utilized in a range of biocidal and fungicidal applications. This disclosure deals with the use of halo active aromatic sulfonamide organic compounds as odor control and/or biocidal agents in a cleaning solution for use with bovines and other dairy animals.

There is provided a method for producing an aqueous acrylamide solution by reacting a composition including acrylonitrile with water to produce acrylamide, in which the composition including acrylonitrile includes 3 to 15 mg of propionitrile per 1 kg of the total weight of the composition including acrylonitrile. According to the present invention, a production method with which it is possible to suppress acrylamide polymerization without lowering quality and thereby obtain a stable aqueous acrylamide solution can be provided.

A portable communication device for phone calling is herein disclosed and enabled. The portable communication device includes a USB interface for connecting to an external USB port of a computing device for enabling phone calling services using the portable communication device. Upon connecting the portable communication device to the external USB port of the computing device, a phone calling software component or data stored in the portable communication device may execute for enabling phone calling services. The portable communication device may also include one or more ports, and may include an interface for Ethernet connection for connecting to the Internet and for making phone calls without the need for connecting the portable communication device to the external USB port. The portable communication device may further include a Wi-Fi wireless component for local wireless communication, and may be implemented as an adapter-sized dongle for providing phone calling services.

Described herein are systems and methods for enabling a collaborative remote desktop environment. The system includes a computing device and a first application instance that has an application state associated therewith. The first application instance includes, or is associated with, a current state component and application data/data files. The system further includes an application launcher that is used to instantiate a second application instance operating either on the same or on a different computing device. The second application instance similarly has an application state associated therewith and is associated with the application launcher. Upon receiving a request from the second user to interact with the first application instance, the application state and the application data/data files are communicated to the application launcher, and the application launcher instantiates the second application instance so that its state is substantially identical to that of the first application instance.

The system and method described herein may leverage passive and active vulnerability discovery to identify network addresses and open ports associated with connections that one or more passive scanners observed in a network and current connections that one or more active scanners enumerated in the network. The observed and enumerated current connections may be used to model trust relationships and identify exploitable weak points in the network, wherein the exploitable weak points may include hosts that have exploitable services, exploitable client software, and/or exploitable trust relationships. Furthermore, an attack that uses the modeled trust relationships to target the exploitable weak points on a selected host in the network may be simulated to enumerate remote network addresses that could compromise the network and determine an exploitation path that the enumerated remote network addresses could use to compromise the network.

An exemplary embodiment of the invention relates to a system and method for providing digital messaging services received from multiple sources over a communications network. The system includes a client system, including a display screen coupled to a communications link; a workstation including a web browser, a memory, and a processor, said workstation coupled to said communications link; a hosting system, including a graphics server, a content server, and a scheduling server, each in communication with each other via a communications link; and a workstation and data storage device coupled to the communications link; and a data storage device for storing data utilized by said hosting system. The client system requests and receives digital messaging services from said hosting system under a subscription agreement. Digital messaging services include advertisements procured from said client system, and one or more local content providers, national advertisers, local advertisers, corporate marketing groups, and advertising agencies. Interactive digital messaging services are also available through the present invention. A user accesses these services via a variety of input devices; such as a bar code scanner, a wireless telephone or personal digital assistant, a kiosk with touch screen design, microphone, or other similar input device.

A CPU executes a communication partner search process for searching for a communication partner (another game machine). The CPU confirms received data content. If identification information included in the received data matches, application identification information saved in a wireless communication module is compared with application identification information included in the received data. When the pieces of application identification information match, a notice that another game machine having exchange data corresponding to the matched application identification information is found is given to a main body. Then, giving/receiving of exchange data is executed to/from another game machine.

A system and method can support user account management in a computing environment. The computing environment can include a video encoding pool to support load balancing and a managing server, such as a privileged account manager server. The video encoding pool includes a set of nodes that are able to perform one or more video processing tasks for another node. Furthermore, the managing server can receive a request from a managed node in the computing environment for delegating a video processing task, and can select one or more nodes from the video encoding pool to load babalance and to perform the video processing task.

A cap (2) is made of sintered hard metal and has on the inside a cylindrical surface (20) and a frusto-conical surface (21) that are true ground. The cap's cylindrical surface (20) is fitted with radial play around an outer cylindrical surface (9) of an underlying middle (1) and the cap's frusto-conical surface (21) has the same inclination as a subjacent frusto-conical surface (14) on the outside of the middle. The cap (2) and the middle (1) are secured to one another by a ring of deformable material sandwiched between their cylindrical surfaces (9, 20). On the outside the cap (2) is formed over its thicker main portion (18) with a trued and polished surface (22) having the same inclination as its inside frusto-conical surface (21) such as to provide the thicker portion (18) with a parallelogrammatic cross-section.

In an apparatus for recording and quickly retrieving video signal parts on a magnetic tape, during recording information about the local position of each video signal part is automatically stored in a memory associated with the apparatus, which is designed for storing identifying information for a large number of magnetic tape cassettes. The retrieval of each video signal part on each of the cassettes can be effected substantially without delay in the quick rewind mode of operation.

The disclosed device enables the recording of television broadcasts which are preprogrammed in a memory. The presence of data lines of the television signal in combination with the presence of a color television signal is checked. When the data lines stop, the video recorder is switched on in real time by a clock time signal.

A device and method provide for an accurate output from a unit, such as an oscillator and/or clock providing an output indicative of frequency and/or time. The device includes a processing section having a microprocessor that develops a model characterizing the performance of the device, including establishing predicted accuracy variations, and the model is then used to correct the unit output. An external reference is used to provide a reference input for updating the model, including updating of predicted variations of the unit, by comparison of the reference input with the unit output. The ability of the model to accurately predict the performance of the unit improves as additional updates are carried out, and this allows the interval between the updates to be lengthened and/or the overall accuracy of the device to be improved. The accuracy of the output is thus adaptively optimized in the presence of systematic and random variations.

An LCD is integrated with the cover glass of a wrist watch radio paging receiver which indicates the time data with a dial plate and hands, and a message is displayed on the cover glass by controlling this LCD. In this message display, the parts of the characters indicating the message are made transparent and the remaining parts intercept light. In this manner, message display is made possible by the difference in light transmissivity.

A system includes a system time counter associated with a micro controller and a secure clock module having a real time clock and an elapsed time counter. The system synchronizes operation between the secure clock module and the system time counter. The synchronized time entered into the system time counter is utilized in the operation of the system. The real time clock time can be caused to be entered into the elapsed time counter at certain point in the operation of the system. The relationship of the time provide enhanced systems security.

A Redundant Array of Independent Disks (RAID) controller receives new data that is to be written, wherein the new data is indicated in blocks of a first block size. The RAID controller reads old data, and old parity that corresponds to the old data, stored in blocks of a second block size that is larger in size than the first block size. The RAID controller computes new parity based on the new data, the old data, and the old parity. The RAID controller writes the new data and the new parity aligned to the blocks of the second block size, wherein portions of the old data that are not overwritten by the RAID controller are also written to the blocks of the second block size.

A Redundant Array of Independent Disks (RAID) controller receives new data that is to be written, wherein the new data is indicated in blocks of a first block size. The RAID controller reads old data, and old parity that corresponds to the old data, stored in blocks of a second block size that is larger in size than the first block size. The RAID controller computes new parity based on the new data, the old data, and the old parity. The RAID controller writes the new data and the new parity aligned to the blocks of the second block size, wherein portions of the old data that are not overwritten by the RAID controller are also written to the blocks of the second block size.

A sequence of storage devices of a data store may include one or more stripesets for storing data stripes of different lengths and of different types. Each data stripe may be stored in a prefix or other portion of a stripeset. Each data stripe may be identified by an array of addresses that identify each page of the data stripe on each included storage device. When a first storage device of a stripeset becomes full, the stripeset may be shifted by removing the full storage device from the stripeset, and adding a next storage device of the data store to the stripeset. A class variable may be associated with storage devices of a stripeset to identify the type of data that the stripeset can store. The class variable may be increased (or otherwise modified) when a computer stores data of a different class in the stripeset.

A memory storage apparatus, a memory controller and method for transmitting and identifying data streams are provided. The memory controller passes at least a portion of a data stream received from a host system to a smart card chip of the memory storage apparatus. Then, the host system accurately receives a response message from the smart card chip by executing a plurality of read commands. The memory controller is capable of adding a first verification code to a response data stream sent to the host system, and is capable of adding a write token to each of data segments of the response data stream. The host system confirms the accuracy of the response data stream by verifying the first verification code or by verifying the write token of each of the data segments.

A method, a system and a computer program product for enhancing a cache back invalidation policy by utilizing least recently used (LRU) bits and presence bits in selecting cache-lines for eviction. A cache back invalidation (CBI) utility evicts cache-lines by using presence bits to avoid replacing a cache-line in a lower level cache that is also present in a higher level cache. Furthermore, the CBI utility selects the cache-line for eviction from an LRU group. The CBI utility ensures that dormant cache-lines in the higher level caches do not retain corresponding presence bits set in the lower level caches by unsetting the presence bits in the lower level cache when a line is replaced in the higher level cache. Additionally, when a processor core becomes idle, the CBI utility invalidates the corresponding higher level cache by unsetting the corresponding presence bits in the lower level cache.

A storage device according to an embodiment includes: a host interface connected to a host; a memory including a first buffer that stores a logical address range designated by an invalidation instruction received from the host via the host interface and a second buffer that stores an internal logical address range which is an area combination with the logical address range; a nonvolatile memory; and a controller. The controller includes: an invalidation instruction processor that stores the logical address range designated by the invalidation instruction in the first buffer; an area combination executor that generates the internal logical address range by the area combination with the logical address range and stores the internal logical address range in the second buffer; and an invalidation executor that executes invalidation processing on the nonvolatile memory based on the internal logical address range.

Apparatuses and methods for providing data are disclosed. An example apparatus includes a plurality of memories coupled to a data bus. The memories provide data to the data bus responsive, at least in part, to a first address. The plurality of memories further provide at least a portion of the data corresponding to the first address to the data bus during a sense operation for a second address provided to the plurality of memories after the first address. Each of the plurality of memories provides data to the data bus corresponding to the first address at different times. Moreover, a plurality of memories may provide at least 2N bits of data to the data bus responsive, at least in part, to an address, each of the plurality of memories provide N bits of data to the data bus at different times.

A method and apparatus are disclosed of monitoring a number of virtual machines operating in an enterprise network. One example method of operation may include identifying a number of virtual machines currently operating in an enterprise network and determining performance metrics for each of the virtual machines. The method may also include identifying at least one candidate virtual machine from the virtual machines to optimize its active application load and modifying the candidate virtual machine to change its active application load.

The present application relates to novel substituted 1-benzylcycloalkylcarboxylic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

The present invention provides α-keto alkylperacids and methods for producing and using the same. In particular, α-keto alkylperacids are useful as antimicrobial agents.

The present application relates to novel 3-phenylpropionic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.

In a process for the separation and drying of crude carboxylic acid crystals from a slurry in a solvent, the slurry is supplied to a filter operating at pressure and at a temperature above the atmospheric boiling point of the solvent. A cake of separated crystals is removed from the filter and passed to a thermal dryer. In a system for the separation and drying of crude carboxylic acid from a slurry in a solvent, a pressure filter device has a slurry inlet and an outlet for a cake of carboxylic acid crystals. The system also has a thermal dryer and means for transporting the cake of carboxylic acid crystals from the pressure filter device to the dryer. The pressure filter device is configured to operate at a pressure and temperature above the atmospheric boiling point of the solvent.

A process is provided for recovering aliphatic monocarboxylic acids having from 4 to 11 carbon atoms from the distillation residue obtained in the oxidation of the corresponding aldehyde by means of oxygen or oxygen-containing gas mixtures in the presence of alkali metal carboxylates or alkaline earth metal carboxylates to form the corresponding monocarboxylic acid and subsequent distillation, characterized in that the distillation residue is reacted with an aqueous acid in a tube reactor and the two-phase mixture flowing out from the tube reactor is introduced into a settling vessel in which the organic phase which separates out has a pH of 4.5 or less.

The present invention relates to the use of at least one sulfonic acid for recovering glycerol resulting from a reaction crude from transesterification of glycerides, in particular of triglycerides of vegetable and/or animal origin. The invention also relates to a process for purifying glycerol obtained as a by-product of triglyceride transesterification during the preparation of fatty acids, fatty esters and/or fatty acid salts, and also to a combined process for preparing, on the one hand, fatty acids, fatty esters and/or fatty acid salts and, on the other hand, glycerol, from triglycerides, using at least one sulfonic acid.

Methods of producing terephthalic acid are described. The methods involve using a substantially pure p-toluic acid stream. The substantially pure p-toluic acid stream, a solvent comprising an ionic liquid and optionally a carboxylic acid, a bromine source, a catalyst, and an oxidizing agent are contacted to produce a product comprising terephthalic acid.

The amount of propionic acid produced in the process of oxidizing propane to acrylic acid is reduced by using a reactor with a length/diameter ratio >10 and/or maintaining the difference between the target reaction temperature and the peak temperature within the reactor to less than 20° C.

The present invention relates to a method for increasing L-methionine productivity and organic acid productivity. More particularly, the present invention relates to a method which involves adding a mixture containing methyl mercaptan and dimethyl sulfide at a appropriate ratio to O-acetyl homoserine or O-succinyl homoserine and to an enzyme having an activity of converting methionine precursor into L-methionine, so as to perform an enzyme reaction, to thereby improve the conversion rate of L-methionine and organic acid from the L-methionine precursor, and thus increasing L-methionine yield as compared to conventional method.

The present invention provides a method for purifying and recovering propionic acid from an aqueous mixture containing a fermentation product obtained from a fermentation process using glycerol as substrate, the method comprising optionally acidifying the aqueous mixture to a pH below 4.5, subjecting the aqueous mixture to an extraction with extracting agent containing a heavy extractant and optionally a light extractant as a diluent to obtain an extract comprising the extracting agent and organic acids, and a raffinate comprising water and any unreacted glycerol, and subjecting the extract to vacuum evaporation to separate propionic acid-containing organic acids from the extractant.

A method for producing acrylic acid and/or an ester thereof from a raw material composition containing hydroxypropionic acid and/or an ester thereof, the method including the steps of: (a) evaporating the raw material composition; and (b) dehydrating the evaporated raw material composition by contact with a dehydration catalyst, wherein the total amount of hydroxypropionic acid and/or an ester thereof supplied in the step (b) is controlled to be 70% by mass or more based on 100% by mass of the total amount of hydroxypropionic acid and/or an ester thereof supplied in the step (a).

A process for producing (meth)acrylic acid comprising the step of repeating a crystallization operation “n” times to produce purified (meth)acrylic acid from crude (meth)acrylic acid, wherein: the each crystallization operation comprises a crystallizing step and a melting step; a polymerization inhibitor is not added to a (meth)acrylic acid melt obtained in the melting step of the first to n−1th crystallization operation(s) and a (meth)acrylic acid solution subjected to the crystallizing step of the second to nth crystallization operation(s); and a concentration of a polymerization inhibitor in a (meth)acrylic acid solution subjected to the crystallizing step of the first crystallization operation is adjusted so that a concentration of the polymerization inhibitor in a (meth)acrylic acid solution subjected to the crystallizing step of the nth crystallization operation is 2 ppm by mass or higher.

A method for preparing a high purity (e.g. greater than 70 wt. %) mono-hydrolyzed acyl halide compound as a precipitate from solution comprising the steps of preparing a solution comprising: i) at least 80 v/v % of a hydrocarbon solvent, ii) water at a molar concentration greater than its solubility limit within the solvent but less that its solubility limit in solution, iii) a tri-hydrocarbyl phosphate compound, and iv) a polyfunctional acyl halide compound at molar ratio to both water and the tri-hydrocarbyl phosphate compound of at least 1:1.

In a process for removing aromatic carboxylic acid from a slurry thereof in solvent, the slurry is split into sub streams and each of said sub streams is supplied to a respective rotary pressure filter such that the sub stream pass through the filters in parallel. Gas is passed through the rotary pressure filters in series in an open-loop arrangement.

The present invention relates to methods for safe and efficient use of hydrogen and oxygen in ozonolysis operations. The invention also relates to an ozonolysis process involving elements of both reductive and oxidative ozonolysis which are integrated in a continuous process. In one embodiment, the ozonolysis process of the present invention uses hydrogen and/or oxygen generated from water and electricity, which may be recycled to generate water and/or electricity.

A process for producing unsaturated carboxylic acids or unsaturated nitriles by vapor phase oxidation reaction of their corresponding C3 to C5 alkanes, C3 to C5 alkenes, and mixtures thereof, as a hydrocarbon starting material, wherein the process performance is monitored and the path of gasses through catalyst beds is altered. Improved catalyst lifetimes may be achieved.

Processes are disclosed for the conversion of 1,6-hexanediol to adipic acid employing a chemocatalytic reaction in which 1,6-hexanediol is reacted with oxygen in the presence of particular heterogeneous catalysts including at least one of platinum or gold. The metals are preferably provided on a support selected from the group of titania, stabilized titania, zirconia, stabilized zirconia, silica or mixtures thereof, most preferably zirconia stabilized with tungsten. The reaction with oxygen is carried out at a temperature from about 100° C. to about 300° C. and at a partial pressure of oxygen from about 50 psig to about 2000 psig.

Provided are processes for producing high-purity succinic acid from a succinic-acid-containing liquid through crystallization.

A production process of a fluorosulfuric acid aromatic-ring ester according to the present invention includes reaction of an aromatic-ring hydroxyl compound with sulfuryl fluoride (SO2F2) in the presence of a tertiary amine except pyridine and methylpyridine. The sulfuryl fluoride, used as the reactant in the production process according to the present invention, is widely adapted as a fumigant and is easily available on a large scale. Further, the target compound can be obtained rapidly with a high yield under moderate reaction conditions in the production process according to the present invention. In this way, all of the prior art problems can be solved in the production process according to the present invention. The production process according to the present invention is thus particularly useful for industrial production of the fluorosulfuric acid aromatic-ring ester.

Various embodiments of the present invention generally disclose systems and processes for the conversion of a feed stream comprising at least one C8 aromatic into a product stream comprising isophthalic acid and purified terephthalic acid (IPA/TA).

The present invention concerns a TCTP antagonist, in particular a nucleic acid targeting an m RNA encoding Translationally-Controlled Tumor Protein (TCTP), wherein said nucleic acid is capable of reducing the amount of TCTP in cells, for use in the treatment or prevention of hormone-independent cancer or chemo-resistant cancer, such as an androgen-independent prostate cancer.

The invention describes new structures of the nucleotide conjugates (nuc-macromolecules) comprising at lease one nucleotide moiety coupled to at least one macromolecular compound via a short linker. These conjugates can be used as substrates for various kinds of polymerizing enzymes in the enzymatic synthesis of nucleic acids. In particular, these compounds can be used for labeling nucleic acids.

Disclosed herein are methods and reagents for determining the responsiveness of cancer to an epidermal growth factor receptor (EGFR) targeting treatment. The detection of these mutations will allow for the administration of gefitinib, erlotinib and other tyrosine kinase inhibitors to those patients most likely to respond to the drug.

The present invention is related to an L nucleic acid that binds to an SDF-1.

An antisense molecule capable of binding to a selected target site to induce exon skipping in the dystrophin gene, as set forth in SEQ ID NO: 1 to 202.

This invention relates to a process for preparing an oligonucleotide 5'-triphosphate. The process comprises the steps of: (a) synthesizing an oligonucleotide having a 5' hydroxyl moiety; (b) reacting the 5' hydroxyl moiety with a reagent of formula I: to convert the 5' hydroxyl moiety to a 5'-H-phosphonate, wherein R1 and R2 are each independently selected from the group consisting of haloalkyl, aryl, substituted aryl, heteroaryl, substituted heteroaryl, cycloalkyl, substituted cycloalkyl, heterocycle, and substituted heterocycle, acyl, phosphoryl, substituted alkyl acyl, substituted heteroalkyl acyl, substituted aryl acyl or substituted heteroaryl acyl, substituted alkyl phosphoryl, substituted heteroalkyl acyl, substituted aryl phosphoryl, and substituted heteroaryl phosphoryl; (c) activating the H-phosphonate of step (b) by reacting the H-phosphonate with a silylating agent, a halogenated oxidizing agent, a nitrogen-containing heteroaryl, or a combination thereof, to form an activated H-phosphonate; and (d) treating the oligonucleotide having an activated H-phosphonate from step (c) with a poly(alkylammonium)pyrophosphate.