d Simultaneous noninvasive recording of electrocardiogram and skin sympathetic nerve activity (neuECG) By feeds.nature.com Published On :: 2020-04-20 Full Article
d CRISPR off-target detection with DISCOVER-seq By feeds.nature.com Published On :: 2020-04-20 Full Article
d Author Correction: Guidance for quantitative confocal microscopy By feeds.nature.com Published On :: 2020-04-20 Full Article
d Cellular thermal shift assay for the identification of drug–target interactions in the <i>Plasmodium falciparum</i> proteome By feeds.nature.com Published On :: 2020-04-27 Full Article
d Simultaneous quantification of protein–DNA interactions and transcriptomes in single cells with scDam&T-seq By feeds.nature.com Published On :: 2020-04-29 Full Article
d Tissue-specific alteration of gene expression and function by RU486 and the GeneSwitch system By feeds.nature.com Published On :: 2019-05-21 Full Article
d Lifespan-increasing drug nordihydroguaiaretic acid inhibits p300 and activates autophagy By feeds.nature.com Published On :: 2019-10-02 Full Article
d Daily blue-light exposure shortens lifespan and causes brain neurodegeneration in <i>Drosophila</i> By feeds.nature.com Published On :: 2019-10-17 Full Article
d Short-term NAD<sup>+</sup> supplementation prevents hearing loss in mouse models of Cockayne syndrome By feeds.nature.com Published On :: 2020-01-07 Full Article
d Repository of proposed pathways and protein–protein interaction networks in age-related macular degeneration By feeds.nature.com Published On :: 2020-01-07 Full Article
d CMV-independent increase in CD27−CD28+ CD8+ EMRA T cells is inversely related to mortality in octogenarians By feeds.nature.com Published On :: 2020-01-21 Full Article
d Organotypic human skin culture models constructed with senescent fibroblasts show hallmarks of skin aging By feeds.nature.com Published On :: 2020-03-06 Full Article
d COVID-19 outcomes in patients with hematologic disease By feeds.nature.com Published On :: 2020-05-06 Full Article
d High rate of durable remissions post autologous stem cell transplantation for core-binding factor acute myeloid leukaemia in second complete remission By feeds.nature.com Published On :: 2020-05-06 Full Article
d Phase I trial of maintenance selinexor after allogeneic hematopoietic stem cell transplantation for patients with acute myeloid leukemia and myelodysplastic syndrome By feeds.nature.com Published On :: 2020-05-06 Full Article
d Rituximab for desensitization during HLA-mismatched stem cell transplantation in patients with a positive donor-specific anti-HLA antibody By feeds.nature.com Published On :: 2020-05-08 Full Article
d Donor-derived DNA variability in fingernails of acute myeloid leukemia patients after allogeneic hematopoietic stem cell transplantation detected by direct PCR By feeds.nature.com Published On :: 2020-05-09 Full Article
d Safety and efficacy of chimeric antigen receptor T-cell therapy in relapsed/refractory multiple myeloma with renal impairment By feeds.nature.com Published On :: 2020-05-09 Full Article
d NT5DC2 promotes tumor cell proliferation by stabilizing EGFR in hepatocellular carcinoma By feeds.nature.com Published On :: 2020-05-07 Full Article
d Irradiation induces cancer lung metastasis through activation of the cGAS–STING–CCL5 pathway in mesenchymal stromal cells By feeds.nature.com Published On :: 2020-05-07 Full Article
d Differential effectiveness of tyrosine kinase inhibitors in 2D/3D culture according to cell differentiation, p53 status and mitochondrial respiration in liver cancer cells By feeds.nature.com Published On :: 2020-05-07 Full Article
d The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors By feeds.nature.com Published On :: 2020-05-07 Full Article
d QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism By feeds.nature.com Published On :: 2020-05-07 Full Article
d WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2 By feeds.nature.com Published On :: 2020-05-07 Full Article
d LncRNA <i>SNORD3A</i> specifically sensitizes breast cancer cells to 5-FU by sponging miR-185-5p to enhance UMPS expression By feeds.nature.com Published On :: 2020-05-07 Full Article
d NF-kappa B interacting long noncoding RNA enhances the Warburg effect and angiogenesis and is associated with decreased survival of patients with gliomas By feeds.nature.com Published On :: 2020-05-07 Full Article
d MicroRNA let-7c (MIRLET7C; let-7c), miR-99a and miR-125b as prognostic markers of luminal breast cancer By feeds.nature.com Published On :: 2014-12-18 Studies in patient samples and cell culture suggest let-7c, miR-99a and miR-125b could serve as prognostic markers in patients with estrogen receptor–positive luminal breast cancers. Full Article
d Chromosome 11 open reading frame 30 (C11orf30), calpain small subunit 1 (CAPNS1; CAPN4), signal transducer and activator of transcription 6 (STAT6) and ankyrin repeat domain 27 (ANKRD27) as diagnostic markers for eosinophilic esophagitis (EoE) By feeds.nature.com Published On :: 2014-12-18 Genomewide association studies identified four genes that could serve as diagnostic markers and/or therapeutic targets for EoE. Full Article
d Tumor-selective delivery of antisense oligomers (antimiRs) against oncogenic microRNAs By feeds.nature.com Published On :: 2014-12-18 miRNA-targeted antimiRs conjugated to a peptide with a low pH–induced transmembrane structure (pHLIP) could help treat solid tumors. Full Article
d Extending therapeutic protein half-lives via fusion to affibodies with pH-dependent binding to neonatal Fc receptor By feeds.nature.com Published On :: 2014-12-18 Fusing therapeutic proteins to affibodies with pH-dependent binding to neonatal Fc receptor could improve the proteins' half-lives. Full Article
d Nanomolar-scale, high throughput chemical synthesis of drug-like molecules By feeds.nature.com Published On :: 2014-12-18 A high throughput, miniaturized chemical synthesis platform could enable rapid discovery of lead compounds. Full Article
d Dermatophagoides pteronyssinus peptidase 1 (DERP1) By feeds.nature.com Published On :: 2014-12-18 In vitro and rat studies suggest inhibiting the enzymatic activity of house dust mite (HDM) allergens could help treat allergic asthma. Full Article
d Glutathione peroxidase 4 (GPX4) By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest inhibiting ferroptosis could help treat ischemia/reperfusion injury in the liver and kidney. Full Article
d Topoisomerase II binding protein 1 (TOPBP1) By feeds.nature.com Published On :: 2014-12-18 Mouse and cell culture studies suggest inhibiting TOPBP1 could help treat cancer. Full Article
d Globohexaosylceramide (globo-H); stage-specific embryonic antigen-3 (SSEA-3); SSEA-4 By feeds.nature.com Published On :: 2014-12-18 Mouse studies suggest chemically modified carbohydrate conjugates could be useful as antigens for the development of cancer vaccines. Full Article
d Epidermal growth factor receptor 1 (EGFR1; ErbB1; HER1); HER2 (EGFR2; ErbB2; neu); HER3 (EGFR3; ErbB3); VEGF By feeds.nature.com Published On :: 2014-12-18 Tumor cell and mouse studies suggest tetravalent antibodies that target four different antigens could help treat cancers resistant to HER-targeted therapies. Full Article
d Cyclin dependent kinase 7 (CDK7); v-myc myelocytomatosis viral related oncogene neuroblastoma derived (MYCN; NMYC) By feeds.nature.com Published On :: 2014-12-18 In vitro and mouse studies suggest THZ1, a covalent CDK7 inhibitor, could help treat neuroblastoma and other cancers driven by MYCN and other c-MYC (MYC)-family oncoproteins. Full Article
d Estrogen receptor; LYN kinase (LYN); phosphoinositide 3-kinase (PI3K) By feeds.nature.com Published On :: 2014-12-18 Studies in mice and human samples suggest inhibiting LYN could help treat estrogen receptor–positive breast cancers resistant to anti-estrogen therapy. Full Article
d Translational tidbits By feeds.nature.com Published On :: 2014-12-18 Yabao and MRC Technology partner in PD; charities form Neuro-MAP to insource pharma's abandoned compounds; Singapore creates a diagnostic hub; a roundup of public-private partnerships. Full Article
d Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity By feeds.nature.com Published On :: 2020-04-27 Full Article
d Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling By feeds.nature.com Published On :: 2020-04-27 Full Article
d Myeloid PTEN promotes chemotherapy-induced NLRP3-inflammasome activation and antitumour immunity By feeds.nature.com Published On :: 2020-05-04 Full Article
d In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states By feeds.nature.com Published On :: 2020-05-04 Full Article
d Differentiation of transplanted haematopoietic stem cells tracked by single-cell transcriptomic analysis By feeds.nature.com Published On :: 2020-05-04 Full Article
