o Sphingolipids distribution at mitochondria-associated membranes (MAM) upon induction of apoptosis. By feedproxy.google.com Published On :: 2020-04-29 Vincent MignardApr 29, 2020; 0:jlr.RA120000628v1-jlr.RA120000628Research Articles Full Article
o Catalytic residues, substrate specificity, and role in carbon starvation of the 2-hydroxy FA dioxygenase Mpo1 in yeast By feedproxy.google.com Published On :: 2020-04-29 Keisuke MoriApr 29, 2020; 0:jlr.RA120000803v1-jlr.RA120000803Research Articles Full Article
o Metabolic regulation of the lysosomal cofactor bis(monoacylglycero)phosphate in mice By feedproxy.google.com Published On :: 2020-04-29 Gernot F. GrabnerApr 29, 2020; 0:jlr.RA119000516v1-jlr.RA119000516Research Articles Full Article
o Development of a sensitive and quantitative method for the identification of two major furan fatty acids in human plasma By feedproxy.google.com Published On :: 2020-04-01 Long XuApr 1, 2020; 61:560-569Methods Full Article
o A Direct Fluorometric Activity Assay for Lipid Kinases and Phosphatases By feedproxy.google.com Published On :: 2020-04-27 Jiachen SunApr 27, 2020; 0:jlr.D120000794v1-jlr.D120000794Methods Full Article
o Lithium ion adduction enables UPLC-MS/MS-based analysis of multi-class 3-hydroxyl group-containing keto-steroids By feedproxy.google.com Published On :: 2020-04-01 Qiuyi WangApr 1, 2020; 61:570-579Methods Full Article
o Heritability of 596 lipid species and genetic correlation with cardiovascular traits in the Busselton Family Heart Study By feedproxy.google.com Published On :: 2020-04-01 Gemma CadbyApr 1, 2020; 61:537-545Patient-Oriented and Epidemiological Research Full Article
o HDL and pancreatic {beta} cells: a SMO-king gun? By feedproxy.google.com Published On :: 2020-04-01 Liam R. BrunhamApr 1, 2020; 61:468-469Commentary Full Article
o Phosphatidylinositol Metabolism, Phospholipases, Lipidomics, and Cancer:In Memoriam of Michael J. O. Wakelam (1955-2020) By feedproxy.google.com Published On :: 2020-04-28 Edward A DennisApr 28, 2020; 0:jlr.T120000868v1-jlr.T120000868Tribute Full Article
o HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic {beta}-cells in vitro by activation of Smoothened By feedproxy.google.com Published On :: 2020-04-01 Mustafa YalcinkayaApr 1, 2020; 61:492-504Research Articles Full Article
o In Memoriam: Lina M. Obeid (1957-2019) By feedproxy.google.com Published On :: 2020-04-01 Ashley J. SniderApr 1, 2020; 61:466-467Tribute Full Article
o Dynamics of sphingolipids and the serine palmitoyltransferase complex in rat oligodendrocytes during myelination By feedproxy.google.com Published On :: 2020-04-01 Deanna L. DavisApr 1, 2020; 61:505-522Research Articles Full Article
o A simple method for sphingolipid analysis of tissues embedded in optimal cutting temperature compound By feedproxy.google.com Published On :: 2020-04-27 Timothy D RohrbachApr 27, 2020; 0:jlr.D120000809v1-jlr.D120000809Methods Full Article
o Of mice and men: murine bile acids explain species differences in the regulation of bile acid and cholesterol metabolism By feedproxy.google.com Published On :: 2020-04-01 Sara StranieroApr 1, 2020; 61:480-491Research Articles Full Article
o Hexacosenoyl-CoA is the most abundant very long-chain acyl-CoA in ATP binding cassette transporter D1-deficient cells By feedproxy.google.com Published On :: 2020-04-01 Kotaro HamaApr 1, 2020; 61:523-536Patient-Oriented and Epidemiological Research Full Article
o Schnyder corneal dystrophy-associated UBIAD1 is defective in MK-4 synthesis and resists autophagy-mediated degradation By feedproxy.google.com Published On :: 2020-05-01 Dong-Jae JunMay 1, 2020; 61:746-757Research Articles Full Article
o ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPLs hydrolase domain By feedproxy.google.com Published On :: 2020-04-23 Kristian K KristensenApr 23, 2020; 0:jlr.ILR120000780v1-jlr.ILR120000780Images in Lipid Research Full Article
o Circulating oxidized LDL increased in patients with acute myocardial infarction is accompanied by heavily modified HDL. By feedproxy.google.com Published On :: 2020-04-14 Naoko SawadaApr 14, 2020; 0:jlr.RA119000312v1-jlr.RA119000312Research Articles Full Article
o The grease trap: uncovering the mechanism of the hydrophobic lid in Cutibacterium acnes lipase By feedproxy.google.com Published On :: 2020-05-01 Hyo Jung KimMay 1, 2020; 61:722-733Research Articles Full Article
o Myeloid-specific deficiency of pregnane X receptor decreases atherosclerosis in LDL receptor-deficient mice By feedproxy.google.com Published On :: 2020-05-01 Yipeng SuiMay 1, 2020; 61:696-706Research Articles Full Article
o An LC/MS/MS method for analyzing the steroid metabolome with high accuracy and from small serum samples By feedproxy.google.com Published On :: 2020-04-01 Teng-Fei YuanApr 1, 2020; 61:580-586Methods Full Article
o A novel NanoBiT-based assay monitors the interaction between lipoprotein lipase and GPIHBP1 in real time By feedproxy.google.com Published On :: 2020-04-01 Shwetha K. ShettyApr 1, 2020; 61:546-559Methods Full Article
o Roles of endogenous ether lipids and associated PUFA in the regulation of ion channels and their relevance for disease By feedproxy.google.com Published On :: 2020-04-07 Delphine FontaineApr 7, 2020; 0:jlr.RA120000634v1-jlr.RA120000634Research Articles Full Article
o The lncRNA Gm15622 stimulates SREBP-1c expression and hepatic lipid accumulation by sponging the miR-742-3p in mice By feedproxy.google.com Published On :: 2020-03-30 Minjuan MaMar 30, 2020; 0:jlr.RA120000664v1-jlr.RA120000664Research Articles Full Article
o Serum non-esterified fatty acids have utility as dietary biomarkers of fat intake from fish, fish oil and dairy in women By feedproxy.google.com Published On :: 2020-03-31 Sandi M. AzabMar 31, 2020; 0:jlr.D120000630v1-jlr.D120000630Methods Full Article
o LDL subclass lipidomics in atherogenic dyslipidemia:Effect of statin therapy on bioactive lipids and dense LDL By feedproxy.google.com Published On :: 2020-04-15 M John ChapmanApr 15, 2020; 0:jlr.P119000543v1-jlr.P119000543Patient-Oriented and Epidemiological Research Full Article
o Alcohol effects on hepatic lipid metabolism By feedproxy.google.com Published On :: 2020-04-01 Sookyoung JeonApr 1, 2020; 61:470-479Reviews Full Article
o Slc43a3 is a regulator of free fatty acid flux By feedproxy.google.com Published On :: 2020-05-01 Kathrin B. HasbargenMay 1, 2020; 61:734-745Research Articles Full Article
o Dietary plant stanol ester supplementation reduces peripheral symptoms in a mouse model of Niemann-Pick type C1 disease. By feedproxy.google.com Published On :: 2020-04-14 Inês Magro dos ReisApr 14, 2020; 0:jlr.RA120000632v1-jlr.RA120000632Research Articles Full Article
o Metabolic phospholipid labeling of intact bacteria enables a fluorescence assay that detects compromised outer membranes By feedproxy.google.com Published On :: 2020-03-10 Inga NilssonMar 10, 2020; 0:jlr.RA120000654v1-jlr.RA120000654Research Articles Full Article
o The fatty acids from LPL-mediated processing of triglyceride-rich lipoproteins are taken up rapidly by cardiomyocytes By feedproxy.google.com Published On :: 2020-04-02 Haibo JiangApr 2, 2020; 0:jlr.ILR120000783v1-jlr.ILR120000783Images in Lipid Research Full Article
o Skin barrier lipid enzyme activity in Netherton patients is associated with protease activity and ceramide abnormalities By feedproxy.google.com Published On :: 2020-04-07 Jeroen van SmedenApr 7, 2020; 0:jlr.RA120000639v1-jlr.RA120000639Research Articles Full Article
o Membrane domains beyond the reach of microscopy By feedproxy.google.com Published On :: 2020-05-01 Ilya LeventalMay 1, 2020; 61:592-594Commentary Full Article
o Commentary on SSO and other putative inhibitors of FA transport across membranes by CD36 disrupt intracellular metabolism, but do not affect fatty acid translocation By feedproxy.google.com Published On :: 2020-05-01 Henry J. PownallMay 1, 2020; 61:595-597Commentary Full Article
o A novel GPER antagonist protects against the formation of estrogen-induced cholesterol gallstones in female mice By feedproxy.google.com Published On :: 2020-05-01 Chelsea DeLeonMay 1, 2020; 61:767-777Research Articles Full Article
o Comparative profiling and comprehensive quantification of stratum corneum ceramides in humans and mice by LC-MS/MS By feedproxy.google.com Published On :: 2020-04-07 Momoko KawanaApr 7, 2020; 0:jlr.RA120000671v1-jlr.RA120000671Research Articles Full Article
o Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro By feedproxy.google.com Published On :: 2020-03-10 Eyad NaserMar 10, 2020; 0:jlr.RA120000682v1-jlr.RA120000682Research Articles Full Article
o Ebola virus matrix protein VP40 hijacks the host plasma membrane to form the virus envelope By feedproxy.google.com Published On :: 2020-04-15 Souad AmiarApr 15, 2020; 0:jlr.ILR120000753v1-jlr.ILR120000753Images in Lipid Research Full Article
o The data must be accessible to all By feedproxy.google.com Published On :: 2020-04-01 Lila M. GieraschApr 1, 2020; 61:465-465Editorials Full Article
o Dispersed lipid droplets: an intermediate site for lipid transport and metabolism in primary human adipocytes. By feedproxy.google.com Published On :: 2020-04-15 Björn MorénApr 15, 2020; 0:jlr.ILR120000808v1-jlr.ILR120000808Images in Lipid Research Full Article
o Accessibility of cholesterol at cell surfaces By feedproxy.google.com Published On :: 2020-04-23 Kristen A. JohnsonApr 23, 2020; 0:jlr.ILR120000836v1-jlr.ILR120000836Images in Lipid Research Full Article
o GPIHBP1, a partner protein for lipoprotein lipase, is expressed only in capillary endothelial cells By feedproxy.google.com Published On :: 2020-05-01 Xia MengMay 1, 2020; 61:591-591Images in Lipid Research Full Article
o Lipid-tuned Zinc Transport Activity of Human ZnT8 Protein Correlates with Risk for Type-2 Diabetes [Molecular Bases of Disease] By feedproxy.google.com Published On :: 2016-12-30T00:06:37-08:00 Zinc is a critical element for insulin storage in the secretory granules of pancreatic beta cells. The islet-specific zinc transporter ZnT8 mediates granular sequestration of zinc ions. A genetic variant of human ZnT8 arising from a single nonsynonymous nucleotide change contributes to increased susceptibility to type-2 diabetes (T2D), but it remains unclear how the high risk variant (Arg-325), which is also a higher frequency (>50%) allele, is correlated with zinc transport activity. Here, we compared the activity of Arg-325 with that of a low risk ZnT8 variant (Trp-325). The Arg-325 variant was found to be more active than the Trp-325 form following induced expression in HEK293 cells. We further examined the functional consequences of changing lipid conditions to mimic the impact of lipid remodeling on ZnT8 activity during insulin granule biogenesis. Purified ZnT8 variants in proteoliposomes exhibited more than 4-fold functional tunability by the anionic phospholipids, lysophosphatidylcholine and cholesterol. Over a broad range of permissive lipid compositions, the Arg-325 variant consistently exhibited accelerated zinc transport kinetics versus the Trp-form. In agreement with the human genetic finding that rare loss-of-function mutations in ZnT8 are associated with reduced T2D risk, our results suggested that the common high risk Arg-325 variant is hyperactive, and thus may be targeted for inhibition to reduce T2D risk in the general populations. Full Article
o UK Tech Weekly Podcast Episode One: The Internet of Looms (IoL) By play.acast.com Published On :: Mon, 15 Feb 2016 09:59:53 GMT In the inaugural episode of the UK Tech Weekly Podcast host Matt Egan discusses Apple's disastrous Error 53 with David Price, acting editor of Macworld UK. Techworld.com editor Charlotte Jee discusses the London mayoral candidates views on the UK tech industry, including Zach Goldsmith's anti-Uber statement, and online editor Scott Carey jumps in with some inane ideas around fibre broadband. Finally the team talk about YouTube licensing rights, despite knowing absolutely nothing about the subject. See acast.com/privacy for privacy and opt-out information. Full Article
o UK Tech Weekly Podcast Episode Two - The Internet of Acronyms (IoA)MWC, FBI and ROI By play.acast.com Published On :: Fri, 19 Feb 2016 14:32:31 GMT In the second episode of the UK Tech Weekly Podcast host Matt Egan discusses the Mobile World Congress (MWC) with producer Chris Martin before he jets off to Barcelona, including what device launches we are expecting from the likes of LG, Sony and Samsung. Acting editor at Macworld.co.uk David Price chats about the row between Apple and the FBI over encryption (14:50). Finally Scott Carey from Techworld.com discusses challenger banks (25:00) what they are, what the technology looks like and why you should care. See acast.com/privacy for privacy and opt-out information. Full Article
o UK Tech Weekly Podcast - Episode Three: The Internet of Sex Robots - Facebook likes, AI and Trump By play.acast.com Published On :: Fri, 26 Feb 2016 17:02:04 GMT In this week's UK Tech Weekly Podcast host Matt Egan is joined by PC Advisor staff writer Chris Minasians chats about Facebook's new like buttons, the team has contracted smartphone fever from the Mobile World Conference in Barcelona and finally, acting editor of Macworld UK David Price, discusses Donald Trump boycotting Apple. See acast.com/privacy for privacy and opt-out information. Full Article
o UK Tech Weekly Podcast Episode Four - The Internet of Kanye (IoK) By play.acast.com Published On :: Fri, 04 Mar 2016 16:42:12 GMT In this week's UK Tech Weekly Podcast host Matt Egan discusses VR with Lewis Painter, staff writer at PC Advisor and Chris Martin, consumer tech editor at PC advisor. Then Chris Minasians, staff writer at Macworld UK vents about how technology is destroying social interactions IRL (11:30), light stuff for your weekend listening pleasure! Finally (23:00) acting editor of Macworld UK David Price and the gang chat about paid-for-streaming advocate Kanye West doing a naughty and pirating music software. See acast.com/privacy for privacy and opt-out information. Full Article
o UK Tech Weekly Podcast Episode Five - The Internet of eReaders (IoeR) By play.acast.com Published On :: Fri, 11 Mar 2016 13:12:14 GMT This week host Matt Egan is joined by Ashleigh Allsopp, engagement editor of Macworld UK and physical bookshelf enthusiast to discuss eBooks and eReaders following the big Nook and Amazon Kindle news in the week (1:40). Producer Chris Martin chips in to talk about the death of the father of email, Ray Tomlinson, this week and the growth of workplace tools like Slack that are trying to reduce the amount we use email (12:30). Finally regular contributor and acting editor at Macworld UK David Price talks about Apple ransomware (24:00). See acast.com/privacy for privacy and opt-out information. Full Article
o UK Tech Weekly Podcast - Episode Six: The Internet of Board Games (IoBG) + The Budget & AlphaGo By play.acast.com Published On :: Thu, 17 Mar 2016 17:50:14 GMT In this week's UK Tech Weekly Podcast host Matt Egan is joined by first time podder Tamlin Magee (1:50), online editor at ComputerworldUK.com, to discuss the UK tech implications of this year's Budget, including rural broadband and driverless cars. Then Christina Mercer, assistant online editor at Techworld.com, chats AlphaGo (10:00) and board games following the AI's historic win over world Go champion Lee Sedol. Later, resident Virtual Reality (VR) enthusiast and PCAdvisor.co.uk staff writer Lewis Painter discussed "the big three" VR headset release dates, pricing and features from HTC, Sony Playstation and Oculus Rift (19:00). Finally, UKTW Podcast regular David Price, acting editor at Macworld.co.uk chats about Apple's big upcoming event (28:45). See acast.com/privacy for privacy and opt-out information. Full Article
o UK Tech Weekly Podcast - Episode Seven: The Internet of Fruit (IoF) Apple, BlackBerry & Raspberry Pi By play.acast.com Published On :: Thu, 24 Mar 2016 16:06:14 GMT In this week's UK Tech Weekly Podcast host Matt Egan is joined by acting editor at Macworld.co.uk David Price to discuss this week's Apple event announcements, from the iPhone SE to the iPad Pro and iOS 9.3. Then first time podder and staff writer at Macworld.co.uk Henry Burrell wades in to discuss Facebook dropping its support for Blackberry and the future of the under-fire mobile phone maker (19:45). Finally, online editor at Techworld.com Scott Carey chats coding in schools following the BBC micro:bit news and how it differs from the Raspberry Pi (27:40). See acast.com/privacy for privacy and opt-out information. Full Article
