Welcoming the 0.25% rate cut by two of the biggest home loan financiers SBI and HDFC, realty sector participants today said the move will help revive interest in the gloomy market. “This is a positive move to boost property sales and spur industry growth. Home buyers who were earlier waiting for rates to come down will now certainly look at buying their dream homes,” industry body Confederation of Real Estate Developers Association of India (Credai) Chairman Lalit Kumar Jain said. “The home loan rate cuts from certain banks have occurred after nearly a year, and will augur well for investment sentiments in the market,” property consultant CBRE South Asia’s Chairman […]

Capitedge India Investment Advisory, a realty fund and asset management firm floated by six former members of Indian realty team of American banking giant Wells Fargo, is coming out with a residential properties-focused fund in India. This would mark its first fresh fundraising exercise after floating an independent investment advisory firm, which is also managing the remaining assets of Wells Fargo after it shut operations in the country last year. While the founding partners are closely associated in operations, Hiral Soni is driving the domestic fundraise and investment strategy, as per the company website. She was previously with Marvel Realtors and had later also set up a boutique investment banking […]

MUMBAI, INDIA – HARMAN Professional Solutions, the global leader in audio, video, lighting and control systems, including networked AV, today announced popular fusion rock band Swarathma, Rajasthani folk singer Mame Khan and percussionist Darshan Doshi...

Sensuous and unique, the smooth white structures of the John F. Kennedy Center for the Performing Arts new, 21st century The REACH complex promises a different sort of experience than its more formal neighbor. Featuring innovative indoor and outdoor...

In the midst of the Covid-19 pandemic and the drastic changes in social interaction that it has caused, who among us has not felt the desire to reach out, to engage, to reconnect? At HARMAN, one of our most dearly-held beliefs is that music empowers...

Our best mathematical theory of consciousness is sparking a rethink of one of science’s hardest problems – how simple matter gives rise to a complex mind

Storks are famous in folklore for delivering human babies to their parents. Conservationists are looking to return the favour with the imminent hatching of several white stork eggs on a 'rewilding' estate in southern England - as the coronavirus outbreak provides a noticeable boost for some wildlife.

Brazil's Bela Vista Biological Refuge Veterinarian Pedro Enrrique Ferreira says the Harpy Eagle hatchling born on April 26 only weighs 150 grams now but could one day grow to weigh some 20 pounds.

The grunts, groans and the sound of pulsing music and crashing weights has returned to some of Beijing's gyms after being closed for nearly three months due to the coronavirus outbreak. Ciara Lee reports.

Storks are famous in folklore for delivering human babies to their parents. Conservationists are looking to return the favour with the imminent hatching of several white stork eggs on a 'rewilding' estate in southern England - as the coronavirus outbreak provides a noticeable boost for some wildlife.

The earliest cave-dwelling animal identified from the dinosaur era is a ghostly white cockroach with tiny eyes and wings that was preserved in amber

Investors withdrew record amounts of money from bond and equity funds in March while money market funds showed record inflows, as the prospect of a massive economic downturn due to coronavirus...

Brazil's Bela Vista Biological Refuge Veterinarian Pedro Enrrique Ferreira says the Harpy Eagle hatchling born on April 26 only weighs 150 grams now but could one day grow to weigh some 20 pounds.

The second season of podcast The Dream debunks much of the wellness industry, but creating empathy for the people caught up in it is where the show shines

Finland’s two-year test of universal basic income has concluded that it doesn't seem to disincentivise working, and improves recipients’ mental and financial well-being

Brazil's Bela Vista Biological Refuge Veterinarian Pedro Enrrique Ferreira says the Harpy Eagle hatchling born on April 26 only weighs 150 grams now but could one day grow to weigh some 20 pounds.

The grunts, groans and the sound of pulsing music and crashing weights has returned to some of Beijing's gyms after being closed for nearly three months due to the coronavirus outbreak. Ciara Lee reports.

Satellites have revealed the fracking heartland of the US is leaking methane, a powerful greenhouse gas, at a record-breaking rate.

Our best mathematical theory of consciousness is sparking a rethink of one of science’s hardest problems – how simple matter gives rise to a complex mind

Finland’s two-year test of universal basic income has concluded that it doesn't seem to disincentivise working, and improves recipients’ mental and financial well-being

Title: Amitiza Treats Irritable Bowel With Constipation
Category: Health News
Created: 5/1/2008 2:00:00 AM
Last Editorial Review: 5/1/2008 12:00:00 AM

Title: Ranibizumab Injections Reduce Retinal Swelling
Category: Health News
Created: 5/2/2008 2:00:00 AM
Last Editorial Review: 5/2/2008 12:00:00 AM

Title: Device Might Detect Breast Cancer-Linked Swelling Sooner
Category: Health News
Created: 5/3/2018 12:00:00 AM
Last Editorial Review: 5/4/2018 12:00:00 AM

Title: 'Buzzing' in Ear Alerted Boy to Very Unwelcome Visitor
Category: Health News
Created: 5/1/2019 12:00:00 AM
Last Editorial Review: 5/2/2019 12:00:00 AM

Title: AHA News: Make Mother's Day Last All Year With Wellness and Appreciation
Category: Health News
Created: 4/29/2020 12:00:00 AM
Last Editorial Review: 4/30/2020 12:00:00 AM

Title: Welcome to the 'Smart Toilet' That Can Spot Disease
Category: Health News
Created: 4/17/2020 12:00:00 AM
Last Editorial Review: 4/17/2020 12:00:00 AM

Title: More Trees, Parks May Mean Longer Lives for City Dwellers
Category: Health News
Created: 4/28/2020 12:00:00 AM
Last Editorial Review: 4/29/2020 12:00:00 AM

Title: Wellbutrin (bupropion)
Category: Medications
Created: 12/31/1997 12:00:00 AM
Last Editorial Review: 2/12/2020 12:00:00 AM

The decline or drying up of groundwater sources near a tunnel route is damaging to groundwater users. Therefore, forecasting the impact of a tunnel on nearby groundwater sources is a challenging task in tunnel design. In this study, numerical and analytical approaches were applied to the Qomroud water conveyance tunnel (located in Lorestan province, Iran) to assess the impact of tunnelling on the nearby extraction water wells. Using simulation of groundwater-level fluctuation owing to tunnelling, the drawdown at the well locations was determined. From the drawdowns and using Dupuit's equation, the depletion of well flow rates after tunnelling was estimated. To evaluate the results, observed well flow rates before and after tunnelling were compared with the predicted flow rates. The observed and estimated water well flows (before and after tunnelling) showed a regression factor of 0.64, pointing to satisfactory results

Glucagon-like peptide-2 (GLP-2) agonists have therapeutic potential in clinical indications in which the integrity or absorptive function of the intestinal mucosa is compromised, such as in short bowel syndrome (SBS). Native hGLP-2, a 33–amino acid peptide secreted from the small intestine, contributes to nutritional absorption but has a very short half-life because of enzymatic cleavage and renal clearance and thus is of limited therapeutic value. The GLP-2 analog teduglutide (Revestive/Gattex; Shire Inc.) has been approved for use in SBS since 2012 but has a once-daily injection regimen. Pharmacokinetic (PK) and pharmacodynamic studies confirm that apraglutide, a novel GLP-2 analog, has very low clearance, long elimination half-life, and high plasma protein binding compared with GLP-2 analogs teduglutide and glepaglutide. Apraglutide and teduglutide retain potency and selectivity at the GLP-2 receptor comparable to native hGLP-2, whereas glepaglutide was less potent and less selective. In rat intravenous PK studies, hGLP-2, teduglutide, glepaglutide, and apraglutide had clearances of 25, 9.9, 2.8, and 0.27 ml/kg per minute, respectively, and elimination half-lives of 6.4, 19, 16, and 159 minutes, respectively. The unique PK profile of apraglutide administered via intravenous and subcutaneous routes was confirmed in monkey and minipig and translated into significantly greater in vivo pharmacodynamic activity, measured as small intestinal growth in rats. Apraglutide showed greater intestinotrophic activity than the other peptides when administered at less-frequent dosing intervals because of its prolonged half-life. We postulate that apraglutide offers several advantages over existing GLP-2 analogs and is an excellent candidate for the treatment of gastrointestinal diseases, such as SBS.

Trumenba (MenB-FHbp; bivalent rLP2086), the first meningococcal serogroup B vaccine approved in the United States and subsequently approved in Europe, Canada, and Australia, is well-characterized. Pfizer devised a control strategy approach by using a simplified control strategy wheel for Trumenba based on International Council for Harmonisation (ICH) Q8 (R2), Q9, Q10, and Q11 guidelines, which provide complementary guidance on pharmaceutical development, quality risk management, quality systems, and development and manufacture of drug substances, respectively. These guidelines ensure product quality using a scientific and risk-based approach. Trumenba contains two factor H binding proteins (FHbps), one from each of the two FHbp subfamilies (A and B), adsorbed onto aluminum phosphate. Trumenba manufacturing processes are complicated by the recombinant protein expression of Subfamily A and B proteins and the nature of the drug product (suspension in syringes); the latter also introduces challenges in controlling product critical quality attributes during the development process. In such complex systems, the control strategy is critical to ensuring consistent desired product quality; it also supports the regulatory requirement of continued improvement through continuous process verification and aids regulatory filing. This article describes Pfizer's approach toward robust control strategy development, built on product and process understanding, and links control strategy to regulatory document sections and flow of controls. Specifically, an approach is presented on product quality attribute criticality determination based on safety and efficacy and on an understanding of process parameter criticality. This was achieved by studying the impact of the approach on product quality attributes to define process parameter and in-process controls. This approach is further explained through Trumenba case studies, highlighting specific quality attributes and the associated controls implemented, and provides a holistic view of controls employed for both drug substance and drug product.

An exceptionally well-preserved specimen of the articulated rhodophyte Permocalculus, compared with P. tenellus sensu Elliott, 1955, is described from fine-grained Upper Permian limestones of the Khuff Formation of Saudi Arabia. Longitudinal medullary and sheaf-like cortical filaments extend through the uniserial series of elongate-globular, concave- and convex-terminating, interlocking segments for which they are interpreted to have functioned in articulation. The filaments tend to splay and branch laterally into the cortex where they terminate at the pores. At the terminal aperture, the filaments extend as bifurcating and possibly trifurcating branches and may serve as the origin of a new segment. Numerous elongate-globular chambers, up to five in each row and intimately involved with the filaments, are developed in the outer medulla and are considered to represent reproductive sporangia. The specimen is considered to have occupied predominantly low-energy, normal to slightly elevated salinity, shallow conditions within the subtidal regime of a lagoon.

Honeywell, the same company that might make your humidifier or home security system, is unveiling a powerful quantum computer that will be available to the public

Doom Eternal does contain gratuitous violence, but the evidence suggests violence in video games doesn't affect people's behaviour in the real world, says Jacob Aron

This film gives us insight into a community that’s already endured plenty even before the zombies arrived.

Adele posted a message to her social media channels this week thanking those on the front lines fighting COVID-19. In the process, the celebrated singer unveiled a thinner frame—and the internet had a lot of thoughts about it, almost all trash.

Enter Bill Maher, noted #MeToo skeptic, with perhaps the most garbage take of them all.

On Friday night, during the interview portion of his HBO show Real Time, the comedian began by placing the bulk of the blame for the high amount of COVID-19 deaths in the U.S. compared to other countries on America’s obesity problem—not, say, the fact that the Trump administration didn’t do a single thing during the month of February to contain the spread of the virus.

Read more at The Daily Beast.

Got a tip? Send it to The Daily Beast here

Chelsea news and gossip is coming in thick and fast so Express Sport is on hand to bring you all the very latest from Stamford Bridge.

I was not surprised either that it took two-plus months for arrests to come of two men and murder charges in the case. This only after the GBI was rightly called in.

In response to the ongoing COVID-19 pandemic.

Zayn Malik and Virgil Abloh are among male celebrities decking out their ears, necks and wrists

There was a time when wearing a boyband-style dogtag was seen as the peak of male adornment, but now men are increasingly embracing jewellery, stacking rings and bracelets and adorning ears with multiple gems.

This week, the former One Direction singer Zayn Malik was announced as the face of the unisex jewellery label Martyre. Virgil Abloh, a weather vane for fashion’s direction of travel, this week launched more office supplies-inspired jewellery – paperclip bracelets, earrings and necklaces decorated with colourful diamonds – and was pictured wearing one of the collection’s bejewelled necklaces.

Foods, such as French fries, cheese, cookies, soda, and sports and energy drinks, are commonly found in the diets of United States adults with inflammatory bowel disease, according to a new study.

Virat Kohli and Anushka Sharma have contributed Rs 5 lakh each for police welfare as the world battles coronavirus.

U.S. President Donald Trump said on Wednesday he did not wear a mask during a tour on Tuesday of a Honeywell International Inc factory in Arizona after consulting the company's chief executive, despite requirements at the plant that workers wear them.

“It’s like life is on hold — everything is on hold,” one new mother said.

Conservation groups are fighting the creation of 3,500 gas wells in Wyoming that threaten a 170-mile path

The Path of the Pronghorn is a 170-mile migration route that the antelope-like creatures have traveled annually for 6,000 years. It is one of North America’s last remaining long-distance terrestrial migration corridors.

And it is at risk. This week conservation groups filed a legal petition challenging the Trump administration’s plan to allow 3,500 new gas wells in south-western Wyoming that would block the route.

Historically, recessions have hit men harder. This time it's different, economists say.