Preterm birth and faster infant growth have been identified as independent risk factors for autism-spectrum disorders (ASD). However, associations between prematurity and ASD-related traits as a continuum and effects of infant growth among those born preterm are still little studied.

VLBW young adults reported higher levels of ASD-related traits, particularly traits related to poorer social skills. Within the VLBW group, faster growth in weight, height, and head circumference from birth to term was associated with lower levels of ASD-related traits. (Read the full article)

Most prospective cohort studies of acquired demyelinating syndromes in children have focused on the genetic, environmental, and neuroimaging predictors of multiple sclerosis. Less is known regarding the severity of the incident demyelinating event and predictors of residual attack–related physical disability.

In a national, prospective longitudinal study, incident acquired demyelinating syndromes in children were characterized in terms of physical deficits and acuity at onset, and recovery over the first 12 months. Follow-up evaluations up to 10 years’ postonset were analyzed. (Read the full article)

Children born preterm at very low birth weight have reduced lung function. Reduced lung function may extend to adult life, but to what extent this outcome is attributable to bronchopulmonary dysplasia and other prenatal and neonatal conditions is not known.

Young adults born preterm at very low birth weight had impaired airflow. This finding suggests an increased risk of later obstructive airways disease and was observed also among those with no bronchopulmonary dysplasia, regardless of other prenatal and neonatal complications. (Read the full article)

Maternal gestational weight gain is associated with childhood overweight. It is unknown whether gestational weight gain programs the child’s health or whether gestational weight gain is an indicator of postnatal behavioral factors.

We disentangled these influences by studying the effect of gestational weight gain simultaneously with postdelivery maternal weight change as an indicator for shared family lifestyle on child’s weight development and found that both had an independent effect. (Read the full article)

This article, published ahead of print on 28 July 2008, has been withdrawn by the authors. Although moderate synergy between P2-RANTES and C peptides can be observed with high statistical significance in cell fusion assays, this synergy was not able to be verified in HIV viral assays. The authors regret the overstatement of synergy and will revise the paper for publication at a later date.

Staphylococcus aureus osteomyelitis is a debilitating infection of bone. Treatment of osteomyelitis is impaired by the propensity of invading bacteria to induce pathologic bone remodeling that may limit antibiotic penetration to the infectious focus. The nonsteroidal anti-inflammatory drug diflunisal was previously identified as an osteoprotective adjunctive therapy for osteomyelitis, based on the ability of this compound to inhibit S. aureus quorum sensing and subsequent quorum-dependent toxin production. When delivered locally during experimental osteomyelitis, diflunisal significantly limits bone destruction without affecting bacterial burdens. However, because diflunisal's "quorum-quenching" activity could theoretically increase antibiotic recalcitrance, it is critically important to evaluate this adjunctive therapy in the context of standard of care antibiotics. The objective of this study is to evaluate the efficacy of vancomycin to treat osteomyelitis during local diflunisal treatment. We first determined that systemic vancomycin effectively reduces bacterial burdens in a murine model of osteomyelitis, and identified a dosing regimen that decreases bacterial burdens without eradicating infection. Using this dosing scheme, we found that vancomycin activity is unaffected by the presence of diflunisal in vitro and in vivo. Similarly, locally-delivered diflunisal still potently inhibits osteoblast cytotoxicity in vitro and bone destruction in vivo in the presence of sub-therapeutic vancomycin. However, we also found that the resorbable polyurethane foams used to deliver diflunisal serve as a nidus for infection. Taken together, these data demonstrate that diflunisal does not significantly impact standard of care antibiotic therapy for S. aureus osteomyelitis, but also highlight potential pitfalls encountered with local drug delivery.

BACKGROUND AND OBJECTIVES:

Children born very preterm (VPT) are at high risk of cognitive impairment that impacts their educational and social opportunities. This study examined the predictive accuracy of assessments at 2, 4, 6, and 9 years in identifying preterm children with cognitive impairment by 12 years.

True to its name, Home Chef is the homiest of meal services we've tried. The recipes are simple and not too adventurous, but for some home chefs, that's a good thing.

Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.

Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.

The march of Marvel off of Netflix continues and this month a few DC films join in, too.

When reading articles that reference empirical research, we need to examine how the author makes assumptions before considering the study as "proof."

T. Michael O'Shea
Jul 1, 1999; 104:15-21
ARTICLES

Wolfgang Lindner
May 1, 1999; 103:961-967
ARTICLES

Richard A. Ehrenkranz
Aug 1, 1999; 104:280-289
ARTICLES

Jeffrey D. Horbar
Jul 1, 2002; 110:143-151
ARTICLES

Barbara J. Stoll
Aug 1, 2002; 110:285-291
ARTICLES

Young adults born prematurely with very low birth weight (≤1500 g) have higher blood pressure than do their counterparts born at term. We tested whether they also have higher blood pressure reactivity to psychosocial stress, which may be a more-specific predictor of long-term cardiovascular morbidity. Systolic and diastolic blood pressure levels for 44 very low birth weight adults (mean age: 23.1 years; SD: 2.3 years) and 37 control subjects (mean age: 23.6 years; SD: 2.0 years) were measured through noninvasive finger photoplethysmography during a standardized psychosocial stress challenge (Trier Social Stress Test). Baseline and task values and their difference (ie, reactivity) served as outcome variables. In comparison with the control group, the very low birth weight group had 7.9 mm Hg higher diastolic blood pressure during the task and 4.8 mm Hg higher diastolic reactivity, with adjustment for gender and age, height, and BMI at testing. A similar trend was seen for systolic blood pressure during the baseline period and the task, but the group differences were not statistically significant. Our results indicate that very low birth weight is associated with elevated blood pressure reactivity to psychosocial stress and, therefore, may increase the risk of cardiovascular morbidity.

Start your new year off right by getting some new customized items for your business, or just treat yourself to a unique 2020 calendar of your own design, all for a fantastic price.

Payback

Spain's Dani Olmo was man of the match in the final against Germany: see every winner of that honour in 2019.

Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.

Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.

Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.

In the 1980s, OM organised large summer campaigns with the huge task of covering every town and village in France with Christian literature.

Too many districts that use a lot of credit recovery to enable students to finish high school don't have sufficient policy safeguards to ensure that those catch-up courses are high quality, according to a new report.

Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.

Fin24 presenter Moeshfieka Botha talks to Abdulazeez Davids of Kagiso Asset Management about how ratings downgrades affect ordinary South Africans.

Finance Minister Malusi Gigaba has raised important issues about state-owned enerprises - the governance of which ratings agencies are watching closely, says George Sebulela, chair of the Black Business Council.

Buenos Aires, Argentina :: Maintenance crew share Christ's love with local welders helping repair Logos Hope.

The 26 pound drone and its cargo fell to the ground after somehow managing to sever its own parachute rope. It landed 150 feet away from a group of children.

A dream comes true - the first OM recruit from her country sends the next group of recruits to the OM ship.

When a short-term outreach team finds openness among an unreached people group, their church gets motivated to send more people.

“We were strangers, and they called us over to bless us. They didn’t have to give us anything—let alone everything—but they did it with smiles on their faces. They didn’t know us; they didn’t expect anything in return; they just gave,” remembers Nicole.

An OMer shows loves to a young boy at a children's home who finds it easier to connect with animals than with other people.

A man renews his decision to follow Christ after chatting with a volunteer during an OM flash mob in a busy area of Santiago.

A participant of OM Chile's Adventure Team shares about a man who was deeply affected while they visited the homeless in the streets of Santiago.

Delaware’s Department of Insurance is pleased to announce that it is actively recruiting for a qualified independent contractor to staff and run its new Office of Value-Based Health Care Delivery. The Office will assist the Insurance Commissioner and Delaware’s Primary Care Reform Collaborative in evaluating primary care accessibility and affordability statewide. “Reducing health care costs […]

A team of Delaware archeologists and a preeminent anthropologist from the Smithsonian Institution Wednesday will unveil new findings from a years-long study of an archeological site in the West Rehoboth area.

An archaeological study years in the making has revealed a wealth of new information about some of Delaware’s earliest colonial settlers and shed new light on what life would have been like in the region three centuries ago.

Black Friday offers have come from a multitude of brands — high street brands like Vero Moda and Only, smartphone companies like Xiaomi, Sony and Honor, beauty brands like Body Shop, Kiehl’s and Nykaa — infusing much joy among shoppers.

Certain practices in the apparel market continue to loom like dark clouds, says Rishabh Oswal, Executive Director, Monte Carlo.

The biggies have built dark stores, warehousing, last-mile deliveries and launched private labels, but still struggle with low margins.

WhatsApp tricks 2020 for iPhone includes some advanced tips such as how to schedule WhatsApp messages, how to hide online status, and how to send WhatsApp message without adding a contact.

The number of active cases of coronavirus in Uttar Pradesh went up to 1,800 on Saturday, while nearly 1,400 people have been discharged so far, a senior official said.

The testing capacity for COVID-19 has been scaled up to around 95,000 tests per day and a total of 15,25,631 tests have been conducted so far across 332 government and 121 private laboratories, Union...

Agency: LGL Closing Date: 6/15/2020

With increasing interest in Continuous Integration/Continuous Delivery (CI/CD), many SAS Users want to know what can be done for Visual Analytics reports. In this article, I will explain how to use Python and SAS Viya REST APIs to extract a report from a SAS Viya environment and import it into another environment.

Continuous Integration/Continuous Delivery – Using Python and REST APIs for SAS Visual Analytics reports was published on SAS Users.

2019 Recovery MonthEvent includes recovery walk, treatment information, live performances and recovery stories WILMINGTON (Sept. 19, 2019) –The Treatment Access Center (TASC), the primary liaison between the Department of Health and Social Services’ Division of Substance Abuse and Mental Health (DSAMH) and the criminal justice system, will host its first event celebrating Recovery Month. Celebrating […]