IEEE / Institute of Electrical and Electronics Engineers Incorporated

Bus lovers love their comfort zones, while those taking the train are more daring

Aspirational India likes to flaunt snazzy cars, unmindful of the cost to environment

Follow-up studies could lead to inhibitors that block uptake, thus stopping body odor production

The XGIMI Horizon Pro is impressive, sleek, and like a TV without the physical screen

Company: Jesseena Marine Services Private Limited
Experience: 4 to 7
location: Saudi Arabia
Ref: 24828815
Summary: Job Description : Vacancy for one of the Reputed Ministry of Defense -Military Hospital in Saudi Arabia. Criteria: - BSc / Post BSc Nursing from Govt. approved college through regular medium - 4 years experience....

Company: Jesseena Marine Services Private Limited
Experience: 3 to 5
location: Saudi Arabia
Ref: 24828613
Summary: Job Description : Vacancy for one of the Reputed Ministry of Defense -Military Hospital in Saudi Arabia. Criteria: - BSc / Post BSc Nursing from Govt. approved college through regular medium - minimum 3-5 years of ....

Company: Jesseena Marine Services Private Limited
Experience: 4 to 5
location: Saudi Arabia
Ref: 24828612
Summary: Job Description : Vacancy for one of the Reputed Ministry of Defense -Military Hospital in Saudi Arabia. Criteria: - BSc / Post BSc Nursing from Govt. approved college through regular medium - minimum 3-5 years of ....

Authority on New York recovery calls for ‘trillions of dollars’ of infrastructure investment

Multidrug resistance (MDR) in cancer arises from cross-resistance to structurally- and functionally-divergent chemotherapeutic drugs. In particular, MDR is characterized by increased expression and activity of ATP-binding cassette (ABC) superfamily transporters. Sphingolipids are substrates of ABC proteins in cell signaling, membrane biosynthesis, and inflammation, for example, and their products can favor cancer progression. Glucosylceramide (GlcCer) is a ubiquitous glycosphingolipid (GSL) generated by glucosylceramide synthase, a key regulatory enzyme encoded by the UDP-glucose ceramide glucosyltransferase (UGCG) gene. Stressed cells increase de novo biosynthesis of ceramides, which return to sub-toxic levels after UGCG mediates incorporation into GlcCer. Given that cancer cells seem to mobilize UGCG and have increased GSL content for ceramide clearance, which ultimately contributes to chemotherapy failure, here we investigated how inhibition of GSL biosynthesis affects the MDR phenotype of chronic myeloid leukemias. We found that MDR is associated with higher UGCG expression and with a complex GSL profile. UGCG inhibition with the ceramide analog d-threo-1-(3,4,-ethylenedioxy)phenyl-2-palmitoylamino-3-pyrrolidino-1-propanol (EtDO-P4) greatly reduced GSL and monosialotetrahexosylganglioside levels, and co-treatment with standard chemotherapeutics sensitized cells to mitochondrial membrane potential loss and apoptosis. ABC subfamily B member 1 (ABCB1) expression was reduced, and ABCC-mediated efflux activity was modulated by competition with nonglycosylated ceramides. Consistently, inhibition of ABCC-mediated transport reduced the efflux of exogenous C6-ceramide. Overall, UGCG inhibition impaired the malignant glycophenotype of MDR leukemias, which typically overcomes drug resistance through distinct mechanisms. This work sheds light on the involvement of GSL in chemotherapy failure, and its findings suggest that targeted GSL modulation could help manage MDR leukemias.

A new program is giving bicycles to Indigenous youth who move to Winnipeg for school to help them get around the city as they pursue their studies.

Two OM workers share the gospel while riding on buses in Turkey.

Ofentse Mokwena discusses what's needed for opening transport markets and unbundling transport SOEs.

India Ratings and Research (Ind-Ra) on Monday placed Shriram Transport Finance Company’s long-term issuer rating of ‘IND AA+’ on Rating Watch Negative (RWN).

The Court of Appeal has dismissed a claim of disability discrimination brought by a wheelchair user who was unable to travel on a bus because the designated wheelchair space was already occupied by a passenger with a child in a buggy. The Court of A...

If the ‘Bill on Protection against Infectious Diseases 2020’ presently in the Senate is signed into law, anyone found transporting a corpse of someone who died of infectious disease would pay a fine of N2 million.

The post Senate bill proposes N2m fine for transporting corpse without permit appeared first on Vanguard News.

Taxi drivers say some customers spend $100 a week on fares to and from work

While 62 percent of transportation has been restored, locals say bus service has been left behind

England's commuters will need to walk, cycle and even scoot more as ongoing social distancing will force them to seek alternative forms of transport, the Government has announced.

Transport secretary announces £2bn package to get UK walking and cycling instead

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The enormity of the challenge of getting the UK back to work was laid bare on Saturday, as the government acknowledged that the capacity of Britain’s transport network will be reduced by 90%.

The transport minister, Grant Shapps, said at the daily Downing Street press briefing that even if a full public transport service is restored, the government’s two-metre physical distancing rule will mean 10% of the usual number of passengers will be able to travel.

The report presents the potential of new nanomaterials and highlights the remaining challenges for their safe and sustainable introduction in the tyre industry.

This publication presents a major meta-analysis of 'value of a statistical life' (VSL) estimates derived from surveys where people around the world have been asked about their willingness to pay for small reduction in mortality risks.

Boosting private sector investment in sustainable transport infrastructure will be essential as governments seek to meet long-term economic and environmental objectives at a time of constrained public finances, according to a new OECD report.

A reaffirmed commitment to fighting climate change has set Canada on a greener course, but the country needs to quickly implement planned measures to reduce the carbon intensity of its energy industry, particularly in oil sands, and green its transport sector in order to progress towards its 2030 emissions goals, according to a new OECD report.

This report examines what would be needed to achieve zero CO2 emissions from international maritime transport by 2035. It assesses measures that can reduce shipping emissions effectively and describes possible decarbonisation pathways that use different combinations of these measures; and reviews under which conditions these measures could be implemented and presents concrete policy recommendations.

The purpose of this study is to investigate the effect of congestion pricing on the demand for clean transport modes. It draws on an empirical analysis of the effect of Milan’s congestion charge on the use of bike sharing. The analysis indicates that congestion pricing increases daily bike-sharing use by at least 5% in the short term.

Boosting private sector investment in sustainable transport infrastructure will be essential as governments seek to meet long-term economic and environmental objectives at a time of constrained public finances, according to a new OECD report.

The ITF is an intergovernmental organisation within the OECD to tackle mobility issues for the 21st century. The Forum acts as a platform to advance transport policy and practice, with a view to ensuring transport's contribution to economic growth, environmental protection, social inclusion and the preservation of human life and well-being. The ITF 2014 annual Summit is being held in Leipzig, Germany on 21-23 may 2014.

The report presents the potential of new nanomaterials and highlights the remaining challenges for their safe and sustainable introduction in the tyre industry.

"Green growth" and transport combines several different concepts that are central to sustainable mobility, including sustainable economic activity, reduced environmental impact and sustained growth in high quality jobs.

The Annual Summit of the International Transport Forum is the unique platform for a global conversation on strategies for transport in the 21st century. It took place in Leipzig, Germany from 27-29 May 2015, under the Presidency of New Zealand under the theme "Transport, Trade and Tourism".

To mark the opening of the International Transport Forum’s Annual Summit, today’s post addresses three broad issues of the complex and multidimensional triangular relationship between transport, trade and tourism.