GNU SIP Witch is a pure SIP-based office telephone call server that supports generic phone system features like call forwarding, hunt groups and call distribution, call coverage and ring groups, holding, and call transfer, as well as offering SIP rver, or an IP-PBX, and does not try to emulate Asterisk, FreeSWITCH, or Yate.

SIPPTS is a set of tools to audit VoIP servers and devices using the SIP protocol. It is a set of perl scripts that allow you to identify extensions, remotely crack passwords, check for missing authentication to make phone calls, and more.

Microsoft Windows Vista/Server 2008 nsiproxy.sys local kernel denial of service exploit.

The United States has reached a settlement to recover more than US$49 million involving Malaysian sovereign wealth fund 1MDB, the US Department of Justice said.The government of former Malaysian prime minister Najib Razak set up the 1MDB fund in 2009 to promote economic development.The US justice department has estimated more than US$4.5 billion was siphoned out of Malaysia by high-level fund officials and their associates between 2009 and 2014 in a scandal that has also embroiled Goldman Sachs…

Title: Mayzent (siponimod)
Category: Medications
Created: 4/17/2020 12:00:00 AM
Last Editorial Review: 4/17/2020 12:00:00 AM

A novel lytic bacteriophage, ValSw3-3, which efficiently infects pathogenic strains of Vibrio alginolyticus, was isolated from sewage water and characterized by microbiological and in silico genomic analyses. Transmission electron microscopy indicated that ValSw3-3 has the morphology of siphoviruses. This phage can infect four species in the Vibrio genus and has a latent period of 15 min and a burst size of 95 ± 2 PFU/infected bacterium. Genome sequencing results show that ValSw3-3 has a 39,846-bp double-stranded DNA genome with a GC content of 43.1%. The similarity between the genome sequences of ValSw3-3 and those of other phages recorded in the GenBank database was below 50% (42%), suggesting that ValSw3-3 significantly differs from previously reported phages at the DNA level. Multiple genome comparisons and phylogenetic analysis based on the major capsid protein revealed that phage ValSw3-3 is grouped in a clade with five other phages, including Listonella phage phiHSIC (GenBank accession no. NC_006953.1), Vibrio phage P23 (MK097141.1), Vibrio phage pYD8-B (NC_021561.1), Vibrio phage 2E1 (KX507045.1), and Vibrio phage 12G5 (HQ632860.1), and is distinct from all known genera within the Siphoviridae family that have been ratified by the International Committee on Taxonomy of Viruses (ICTV). An in silico proteomic comparison of diverse phages from the Siphoviridae family supported this clustering result and suggested that ValSw3-3, phiHSIC, P23, pYD8-B, 2E1, and 12G5 should be classified as a novel genus cluster of Siphoviridae. A subsequent analysis of core genes also revealed the common genes shared within this new cluster. Overall, these results provide a characterization of Vibrio phage ValSw3-3 and support our proposal of a new viral genus within the family Siphoviridae.

IMPORTANCE Phage therapy has been considered a potential alternative to antibiotic therapy in treating bacterial infections. For controlling the vibriosis-causing pathogen Vibrio alginolyticus, well-documented phage candidates are still lacking. Here, we characterize a novel lytic Vibrio phage, ValSw3-3, based on its morphology, host range and infectivity, growth characteristics, stability under various conditions, and genomic features. Our results show that ValSw3-3 could be a potent candidate for phage therapy to treat V. alginolyticus infections due to its stronger infectivity and better pH and thermal stability than those of previously reported Vibrio phages. Moreover, genome sequence alignments, phylogenetic analysis, in silico proteomic comparison, and core gene analysis all support that this novel phage, ValSw3-3, and five unclassified phages form a clade distant from those of other known genera ratified by the ICTV. Thus, we propose a new viral genus within the Siphoviridae family to accommodate this clade, with ValSw3-3 as a representative member.

Simon Tapper, Joseph J. Nocera, and Gary Burness

Climatic warming is predicted to increase the frequency of extreme weather events, which may reduce an individual's capacity for sustained activity due to thermal limits. We tested whether the risk of overheating may limit parental provisioning of an aerial insectivorous bird in population decline. For many seasonally breeding birds, parents are thought to operate close to an energetic ceiling during the 2-3 week chick-rearing period. The factors determining the ceiling remain unknown, although it may be set by an individual's capacity to dissipate body heat (the heat dissipation limitation hypothesis). Over two breeding seasons we experimentally trimmed the ventral feathers of female tree swallows (Tachycineta bicolor, Vieillot, 1808) to provide a thermal window. We then monitored maternal and paternal provisioning rates, nestling growth rates, and fledging success. We found the effect of our experimental treatment was context-dependent. Females with an enhanced capacity to dissipate heat fed their nestlings at higher rates than controls when conditions were hot, but the reverse was true under cool conditions. Control females and their mates both reduced foraging under hot conditions. In contrast, male partners of trimmed females maintained a constant feeding rate across temperatures, suggesting attempts to match the feeding rate of their partners. On average, nestlings of trimmed females were heavier than controls, but did not have a higher probability of fledging. We suggest that removal of a thermal constraint allowed females to increase provisioning rates, but additionally provided nestlings with a thermal advantage via increased heat transfer during maternal brooding. Our data provide support for the heat dissipation limitation hypothesis and suggest that depending on temperature, heat dissipation capacity can influence reproductive success in aerial insectivores.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and beyond.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and Europe.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and Europe.

Welcome to the Evening Standard's live blog covering the latest transfer news and rumours from the Premier League and Europe.

Here is the COVID-19 situation in Mississippi.

Former Tippah County, Miss., Deputy Sheriff Jeffrey Rogers, 35, pleaded guilty today to a one-count information charging him and former Deputy Sheriff William Rogers with violating the civil rights of an arrestee. William Rogers, 56, who is Jeffrey Rogers’ father, pleaded guilty on Jan. 20, 2009, to the same charge of violating the civil rights of an arrestee.

Marshall E. Sanders, an attorney based in Vicksburg, Miss., was sentenced to 18 months in prison for failure to file tax returns by Magistrate Judge James C. Sumner. In addition, Judge Sumner ordered Sanders to pay restitution to the IRS of $1,025,453.

A federal judge today sentenced Jimmy “Jimbo” Sullivan, the former chief of police in Mendenhall, Miss., to 30 months in prison for using excessive force when he repeatedly stomped on the head of an arrestee. At his guilty plea hearing on Jan. 30, 2009, Sullivan admitted that he used excessive force on July 22, 2005, after joining other law enforcement officials in the apprehension of a man who led police on a car chase.

Former Tippah County, Miss., Deputy Sheriff William Rogers and his son, former Tippah County Deputy Sheriff Jeffrey Rogers, were sentenced in federal court on April 30, 2009, for violating the civil rights of an arrestee by shooting him with a taser unnecessarily.

The Department announced that on May 5, 2009, it will monitor municipal elections in the towns of Cleveland, Como, Meridian and Sardis, Miss., to ensure compliance with the Voting Rights Act of 1965.

On June 2, 2009, the Department of Justice will monitor elections in the following jurisdictions to ensure compliance with the Voting Rights Act of 1965 and other federal voting rights statutes: the towns of Como, Drew, Greenwood, Isola, Louise and Meridian, Miss.; Bergen County, Middlesex County and the borough of Penns Grove, N.J.; and the town of Martin, S.D.

The U.S. Court of Appeals for the Fifth Circuit today rejected a challenge to the conviction of James Ford Seale, a former member of the White Knights of the Ku Klux Klan of Mississippi. Seale was convicted by a federal jury in Mississippi in 2007 and sentenced to three life terms in prison.

The Department today filed a lawsuit against the former owner and managers of Homestead Mobile Home Village, a mobile home park in Gulfport, Miss., for violating the Fair Housing Act by discriminating against black tenants on the basis of race or color.

The United States has joined a whistleblower suit against Science Applications International Corp. (SAIC); Applied Enterprise Solutions (AES); Dale Galloway, Chief Executive Officer of AES; Stephen Adamec, former Director of the Naval Oceanographic Major Shared Resource Center (NAVO MSRC) at the Stennis Space Center in Hancock County, Mississippi; and Robert Knesel, Deputy Director of NAVO MSRC.

Jonathan Haynes, a former police officer with the Jackson, Miss., Police Department, was sentenced today for a civil rights violation for stealing money from a citizen during an off-duty encounter.

Two manufacturing companies, in separate settlements, have agreed to pay civil penalties and take corrective measures to settle Clean Air Act violations resulting from explosions at two plants in 2002 and 2003 in Louisville, Ky., and Pascagoula, Miss.

The agreement was reached under the department’s Project Civic Access initiative to bring localities into full compliance with the Americans with Disabilities Act.

The United States has reached a comprehensive settlement agreement with the city of Jackson, Miss., to improve access to public transportation for individuals with disabilities.

Kyle Palmer, 27, of Biloxi, Miss., was sentenced today by U.S. District Judge Louis Guirola Jr., in the Southern District of Mississippi to 36 months in prison for involuntary manslaughter.

A federal court has ordered the Walthall County, Miss., School District to eliminate policies that have resulted in significant racial segregation among students in the school district.

Michael Shane Minich, 35, a former Lee County, Miss., Sheriff’s Deputy, pleaded guilty today before U.S. District Judge Sharion Aycock, in Aberdeen, Miss., to depriving citizens of their civil rights under color of law by secretly removing cash from their wallets during traffic stops.

A federal court in Jackson, Miss., has ruled in favor of the United States involving a businessman’s attempt to use a KPMG- marketed tax shelter to avoid paying income tax on approximately $18 million in capital gains.

The Justice Department today announced an agreement with Pearl River County, Miss., to improve access to all aspects of civic life for persons with disabilities.

A federal grand jury returned an indictment charging Natchez, Miss., Police Department Officers Elvis Prater, 35, and Dewayne Johnson, 32, with civil rights offenses and other offenses related to the beating of two men in custody, the theft of an arrestee’s credit and debit cards, and the officers’ false statements to federal investigators.

Robert Morris of Crystal Springs, Miss., was sentenced today to 35 years in prison for production, distribution, receipt and possession of child pornography.

The Justice Department today announced that it has reached agreements with New York, Kansas and Mississippi officials to help ensure that military service members and other U.S. citizens living overseas have an opportunity to participate fully in the Nov. 2, 2010, federal general election.

The Justice Department today filed a lawsuit against a Gulfport, Miss., newspaper and a landlord and her agent for violating the Fair Housing Act by discriminating against families with children.

The Justice Department today announced that Mississippi property owner Indigo Investments LLC, has agreed to pay $50,000 in monetary damages and civil penalties to settle the government’s Fair Housing Act lawsuit.

A federal grand jury returned an indictment charging Choctaw County, Miss., Sheriff’s Deputy Billy C. Scott Jr. with civil rights violations and obstructing justice.

Mississippi-based PowerTrain Inc., Wood Sales Inc., and Tool Mart Inc., (collectively known as “PowerTrain”) will jointly pay a civil penalty of $2 million to resolve claims that the company imported and sold almost 80,000 nonroad engines and equipment that were not covered by emissions-related certificates of conformity, and in most cases could not be certified because they exceeded emissions standards under the Clean Air Act.

A jury in Natchez, Miss., yesterday convicted a Natchez Police Department officer of violating the civil rights of an arrestee by stealing credit and debit cards from the arrestee.

Terra Industries Inc., one of the nation’s largest producers of nitric acid and nitrogen fertilizers, has agreed to pay $625,000 in civil penalties to settle alleged violations of the federal Clean Air Act at nine of its plants in Iowa, Mississippi and Oklahoma.