Democratic Gov. Gina Raimondo proposes to allow traditional public schools to be free of certain regulations, including opening up enrollment outside their neighborhoods.

After his haircut, Sen. Ted Cruz said, "It was ridiculous to see somebody sentenced to seven days in jail for cutting hair."

Beaches in Florida and Thailand have tentatively reported increases in nests, due to decreased human presence. But the trend won’t necessarily persist

Despite some pockets of severe activity, Canadians are succeeding at flattening the curve of the COVID-19 pandemic, the country’s federal health minister, Patty Hajdu, said Thursday.

Demand for service is not expected to recover in the coming weeks, says Marine Atlantic.

All of P.E.I.'s 27 confirmed cases of COVID-19 are now considered recovered, said Chief Public Health Officer Dr. Heather Morrison.

As the NHL, NBA and MLB consider resuming play, the issue of international travel poses another hurdle for Canadian-based teams.

A Saskatchewan daughter said her mom has been “confined” to her room at a government run health-care facility due to COVID-19. 

The Saskatchewan Union of Nurses (SUN) is raising concerns about some nurses who volunteered for remote assignments being told they need to refrain from working elsewhere for at least 14 days if they’ve worked in Lloydminster or La Loche.

Despite sharp differences in the impact of COVID-19 in different parts of Ontario, the Ford government is rejecting a region-by-region approach to loosening emergency restrictions.

Government restrictions designed to limit the spread of COVID-19 have virtually crippled Ontario's wine-making industry, as retail and wholesale revenues dry up but the costs of producing wine remains constant.

RESEARCHERS have called for a two-track approach to easing lockdown which would strengthen protection for the most vulnerable but relax restrictions for the majority of the population.

Scottish Golf today revealed that no date has been set for the sport in this country to restart and stressed that lockdown restrictions will remain in place for the foreseeable future.

NICOLA Sturgeon could issue a change to the Scottish Government's policy on allowing outdoor exercise over the weekend - after Wales indicated the guidance will be relaxed from Monday.

(As of 29 April 2020) Information on travel restrictions and advice on quarantine measures.

Twelfth modification allows the Public Health Authority to activate additional workers WILMINGTON, Del. – Governor John Carney on Thursday issued the twelfth modification to his State of Emergency declaration, which will allow the Public Health Authority to activate more out-of-state health care workers to assist in Delaware’s fight against COVID-19.        Read Governor Carney’s updated State […]

Read Full Article at RT.com

The head of Germany’s most populous state has called for the reopening of the country’s French border to be fast-tracked. The federal government earlier warned that such actions risk launching a new wave of Covid-19 infections.
Read Full Article at RT.com

Applies to rinse-off cosmetics and other preparations

IPL is scheduled to begin on March 29 between the Chennai Super Kings and the defending champions Mumbai Indians at the Wankhede Stadium in Mumbai.

As the Coronavirus outbreak intensifies in India, the Ministry of Home Affairs have decided to extend the suspension of existing Indian visas given to foreign nationals.

New 90-day limits on work visas for Chinese journalists followed Beijing’s expulsion of American journalists and raised the threat of further retaliation by the Chinese government.

Venezuela's government is lifting electricity rationing that began more than two months ago due to drought and rising temperatures that affected water levels at the 1,500-square-mile Guri Reservoir.
 

Chief Executive of China’s Hong Kong Special Administrative Region Carrie Lam yesterday announced a relaxing of some social distancing measures, including allowing some entertainment venues to reopen and

It has been reported that the European Commission (the “Commission”) is asking retailers to detail the difficulties they face while trying to sell their products online, as part of the lengthy questionnaires sent to the retailers followi...

The NBA is taking small steps toward a return to normalcy

Australia's most populous states have held back from relaxing coronavirus restrictions although other states began allowing small gatherings and were preparing to open restaurants and shops.

The country's Interior Ministry also announced a new round of hefty fines for quarantine violators.

Kuwait announced a "total curfew" will start Sunday to fight the coronavirus, but did not yet specify details.

Taiwan will gradually ease restrictions on travel and sporting activities, with the island’s health minister saying efforts to control the coronavirus were paying off.The island – home to 23 million people – had reported just 440 cases and six deaths from Covid-19 as of Thursday, with no local transmission for close to a month.Health Minister Chen Shih-chung said that with very few new cases among people returning to the island from elsewhere, the authorities would allow Taiwanese stranded in…

The United States has tightened visa rules for Chinese journalists as the tit-for-tat war on the media between the two sides escalated.The rules, which will take effect on Monday, limit visas for Chinese passport holders to 90 days with the option for an extension, the US Department for Homeland Security said on Friday.Journalists with passports from Hong Kong or Macau will not be affected.“The department is issuing this rule to address the actions of the PRC [People’s Republic of China]…

South Sudan Doctors’ Union say this may hurt millions of South Sudanese.

Hong Kong recorded zero new Covid-19 cases on Saturday, as a government adviser suggested that border control measures between the city and Macau could be the first to be lifted.It was also the 20th day in a row without any local infections, although a handful of imported cases over the past week had taken Hong Kong’s tally to 1,044 with four related deaths.Health experts earlier raised the prospect of Hong Kong being declared free of local transmission if there were no such cases after 28 days…

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Few images conjure the 1930s Depression like people standing in soup lines while farmers dump food they can't sell. That is a tragedy Southeast Asia is fighting to avoid, though it is starting to happen in pockets around the world in the midst of COVID-19. Supply chain disruptions, driven by the pan...

Prime Minister Boris Johnson will keep Britain under a coronavirus lockdown until at least next month -- to the frustration of some in his Cabinet, who behind the scenes are arguing that Downing Street now needs to prioritize the economy, which is heading for its worst recession in 300 years.Cabinet...

Australia's most populous states held back from relaxing coronavirus restrictions on Saturday although other states began allowing small gatherings and were preparing to open restaurants and shops.

Australia will ease social distancing restrictions in a three-step process, Prime Minister Scott Morrison said on Friday, as Canberra aims to remove most curbs by July and get nearly 1 million people back to work amid a decline in coronavirus cases.

Australia will ease social distancing restrictions implemented to slow the spread of the coronavirus in a three-step process, Prime Minister Scott Morrison said on Friday, with the aim of removing all curbs by July. Lauren Anthony reports.

The entry/fusion complex (EFC) consists of 11 conserved proteins embedded in the membrane envelope of mature poxvirus particles. Poxviruses also encode proteins that localize in cell membranes and negatively regulate superinfection and syncytium formation. The vaccinia virus (VACV) A56/K2 fusion regulatory complex associates with the G9/A16 EFC subcomplex, but functional support for the importance of this interaction was lacking. Here, we describe serially passaging VACV in nonpermissive cells expressing A56/K2 as an unbiased approach to isolate and analyze escape mutants. Viruses forming large plaques in A56/K2 cells increased in successive rounds of infection, indicating the occurrence and enrichment of adaptive mutations. Sequencing of genomes of passaged and cloned viruses revealed mutations near the N terminus of the G9 open reading frame but none in A16 or other genes. The most frequent mutation was His to Tyr at amino acid 44; additional escape mutants had a His-to-Arg mutation at amino acid 44 or a duplication of amino acids 26 to 39. An adaptive Tyr-to-Cys substitution at amino acid 42 was discovered using error-prone PCR to generate additional mutations. Myristoylation of G9 was unaffected by the near-N-terminal mutations. The roles of the G9 mutations in enhancing plaque size were validated by homologous recombination. The mutants exhibited enhanced entry and spread in A56/K2 cells and induced syncytia at neutral pH in HeLa cells despite the expression of A56/K2. The data suggest that the mutations perturb the interaction of G9 with A56/K2, although some association was still detected in detergent-treated infected cell lysates.

IMPORTANCE The entry of enveloped viruses is achieved by the fusion of viral and cellular membranes, a critical step in infection that determines host range and provides targets for vaccines and therapeutics. Poxviruses encode an exceptionally large number of proteins comprising the entry/fusion complex (EFC), which enables infection of diverse cells. Vaccinia virus (VACV), the prototype member of the poxvirus family, also encodes the fusion regulatory proteins A56 and K2, which are displayed on the plasma membrane and may be beneficial by preventing reinfection and cell-cell fusion. Previous studies showed that A56/K2 interacts with the G9/A16 EFC subcomplex in detergent-treated cell extracts. Functional evidence for the importance of this interaction was obtained by serially passaging wild-type VACV in cells that are nonpermissive because of A56/K2 expression. VACV mutants with amino acid substitutions or duplications near the N terminus of G9 were enriched because of their ability to overcome the block to entry imposed by A56/K2.

First Minister Nicola Sturgeon has said the Scottish Government is looking into expanding the current guidance about exercise during the lockdown.

Chennai, May 09: Tamil Nadu government has announced some relaxations in the Coronavirus lockdown in non-containment zones from May 11. The extension includes working hours of standalone and neighbourhood shops and allowing private establishments to function with a reduced number of employees

Due to COVID-19, what we think of as traditional funerals are unable take place in Saskatchewan, and it's taking a toll on those who have lost loved ones.

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