In his first public comments on the stadium deal, Angels owner Arte Moreno addressed whether he would replace Angel Stadium or renovate it.

Angels shortstop Andrelton Simmons' long-term future with the franchise remains up in the air heading into the final year of his contract.

Angels owner Arte Moreno explained how Gerrit Cole was his team's primary target in the offseason, but despite his team's big offer, "you knew no matter what I did, we were going to get outbid."

The Communist government kept Thich Quang Do in prison or under house arrest for more than 20 years.

MS Brown
Jul 1, 1980; 21:505-517
Reviews

bmj;369/may07_6/m1803/FAF1faPhoto credit: Abbas GhazanfarOn 25 March Adil El-Tayar, a renowned organ transplantation specialist, became the first working NHS surgeon to die from covid-19 in hospital...

The century-old Reno Rodeo has canceled the 10-day event in June because of the coronavirus pandemic. Reno Rodeo President Craig Downie said in a letter to the rodeo’s board of directors that canceling the event scheduled for June 18-27 was necessary to ensure the safety of participants, fans, vendors, sponsors and volunteers. General Manager George Combs said it was a difficult decision, made in consultation with health experts as well as the Professional Rodeo Cowboys Association.

The National Museum of American History will undergo a dramatic makeover

The Oppo Reno 3 Pro offers solid specs and performance in a flagship-level design for a decidedly midrange price.

DOVER – Delaware State Housing Authority (DSHA) held an event today marking the completion of renovations at Liberty Court, a public housing site in Dover, and recognizing the authority’s 20th year participating in Moving to Work (MTW), a U.S. Department of Housing and Urban Development (HUD) program. Many of the residents at Liberty Court participate […]

$4.5 million investment enhances security, improves employee and visitor experience WILMINGTON, Del. – Governor John Carney, along with Lt. Governor Bethany Hall-Long, members of the General Assembly and members of his cabinet cut the ribbon on Tuesday to celebrate the completion of the first phase of renovations to the Carvel State Office Building in Wilmington. […]

 Seeks to amend noti.No.146/94-Customs dated 13.07.94 so as to modify conditions for shooting equipment

Agency: OMB Closing Date: 7/9/2020

Agency: DTCC Closing Date: 5/12/2020

Agency: OMB Closing Date: 7/8/2020

Governor Dapo Abiodun of Ogun State has regretted how the outbreak of the coronavirus pandemic scuttled his plans to renovate 236 primary health care centres in the state. According to Gov Abiodun, the COVID-19 pandemic was a surprise to him because it happened just as he was beginning to roll out plans to reform the […]

Coronavirus prevented me from renovating 236 health centres in Ogun – Gov Abiodun

1

An exquisite estate in Cherry Hills Village that finished as a finalist for the 2019 Home of the Year in Colorado Homes & Lifestyles Magazine was recently listed for sale at $7.75 million.

Title: Sublocade (buprenorphine extended release)
Category: Medications
Created: 4/17/2020 12:00:00 AM
Last Editorial Review: 4/17/2020 12:00:00 AM

Title: Sublocade (buprenorphine)
Category: Medications
Created: 4/21/2020 12:00:00 AM
Last Editorial Review: 4/21/2020 12:00:00 AM

To the Editor—A 30-day injectable form of buprenorphine branded as SublocadeTM (Buprenorphine XR SQ) was approved by the FDA in 2017. This medication is administered by a health care professional subcutaneously in the abdomen to treat opioid use disorder. This long-acting delivery system holds great promise for many patients who have barriers to taking daily transmucosal buprenorphine-containing medications such as those with poor adherence to a daily medication. It is beneficial for those who have difficulty safely storing their medications, including patients who have children in the home, unstable housing, or live with others who have a use disorder. This product is also an option for patients who prefer mono-product buprenorphine. As Buprenorphine XR SQ is administered directly by a health care professional, it does not contain the abuse-deterrent naloxone that some patients feel causes side effects.

There are two ways to acquire Buprenorphine XR SQ: 1) order product from the distributor (buy and bill); or 2) dispensed from a specialty pharmacy for a specific patient (specialty pharmacy) [1]. For the buy and bill option, the health care setting must be certified through the Risk Evaluation and Mitigation Strategy (REMS) program and adhere to dispensing regulations [2]. We found this challenging to implement in the outpatient setting, thus we pursued the specialty pharmacy option. It ultimately took us nearly one year to complete the process.

The following are the barriers we faced with our first attempt. As a controlled substance, the medication must be stored in a refrigerated lockbox. Before...

Recent studies have strived to find an association between rapid antidepressant effects and a specific subset of pharmacological targets and molecular pathways. Here, we propose a broader hypothesis of encoding, consolidation, and renormalization in depression (ENCORE-D), which suggests that, fundamentally, rapid and sustained antidepressant effects rely on intrinsic homeostatic mechanisms evoked as a response to the acute pharmacological or physiologic effects triggered by the treatment. We review evidence that supports the notion that various treatments with a rapid onset of action, such as ketamine, electroconvulsive therapy, and sleep deprivation, share the ability to acutely excite cortical networks, which increases synaptic potentiation, alters patterns of functional connectivity, and ameliorates depressive symptoms. We proceed to examine how the initial effects are short-lived and, as such, require both consolidation during wake and maintenance throughout sleep to remain sustained. Here, we incorporate elements from the synaptic homeostasis hypothesis and theorize that the fundamental mechanisms of synaptic plasticity and sleep, particularly the homeostatic emergence of slow-wave electroencephalogram activity and the renormalization of synaptic strength, are at the center of sustained antidepressant effects. We conclude by discussing the various implications of the ENCORE-D hypothesis and offer several considerations for future experimental and clinical research.

The American Board of Family Medicine routinely surveys its Diplomates in each national graduating cohort 3 years out of training. These data were used to characterize early career family physicians whose services include management of pregnancy and prescribing buprenorphine. A total of 261 (5.1%) respondents both provide maternity care and prescribe buprenorphine. Family physicians who care for pregnant women and also prescribe buprenorphine represented 50.4% of all buprenorphine prescribers. The family physicians in this group were trained in a small number of residency programs, with only 15 programs producing at least 25% of graduates who do this work.

Angels owner Arte Moreno's company could disclose before the end of the month whether it plans to build a new ballpark or renovate Angel Stadium.

A smiling, happy Brydi Saul is on a mission to get to the Paralympics. But rewind three years, and it was a very different story.

First up: monthly depot formulation from Indivior

“I am pleased to welcome Ignacia back to the Department and the Environment and Natural Resources Division,” said Attorney General Holder.

Ignacia S. Moreno, Assistant Attorney General for the Environment and Natural Resources Division, welcomes the members of the division’s senior leadership.

Safeguarding our environment and protecting our natural resources is, and must be, a priority for the Justice Department. To this work, Ignacia will bring excellent judgment, a proven ability to bring people together, and an unwavering devotion to enforcing current law and defending key federal programs.

It is always a pleasure for me to see my long-time friends at the D.C. Bar. I have been a D.C. Bar member since 1991 – that is 20 years – and have served on various Bar committees and participated in pro bono activities sponsored by the Bar.

The construction manager for a renovation project at the Equitable Building in Des Moines, Iowa, pleaded guilty today in federal court to conspiracy to violate the Clean Air Act and for violating the Clean Air Act’s work practice standards related to asbestos removal.

The owner of the Equitable Building in Des Moines, Iowa, pleaded guilty today in federal court in Des Moines to conspiracy to violate the Clean Air Act and to violating the Clean Air Act’s work practice standards related to asbestos removal.

Marking the eighth annual Earth Day Service Celebration today, Deputy Attorney General James Cole and Assistant Attorney General Ignacia S. Moreno commended volunteers from the Justice Department’s Environment and Natural Resources Division as they began work on a future Community Greening Center near Marvin Gaye Park in Northeast Washington, D.C.

"Protecting and defending tribal resources and rights, and vigorously enforcing the nation’s environmental and natural resources laws, are crucial parts of the Justice Department’s efforts to achieve healthier communities and a sustainable future for native people."

Ignacia S. Moreno, Assistant Attorney General for the Justice Department’s Environment and Natural Resources Division, today announced two new members of her senior leadership team.

"The settlement requires Regal Stone Limited and Fleet Management Limited to pay more than $44 million for natural resource damages and penalties, and to reimburse the government entities for response costs incurred as a result of the spill," said Assistant Attorney General Moreno.

The Environment Division’s enforcement efforts over the years have achieved dramatic reductions in emissions and discharges of harmful pollutants to the Nation’s air, land and water.

Ignacia S. Moreno, Assistant Attorney General of the Environment and Natural Resources Division, announced today that she will be leaving the Department of Justice on June 7, 2013.

The Justice Department announced today that the U.S. District Court of Nevada has approved a settlement in which the owners and operators of Rosewood Park Apartments, a 902 unit apartment complex in Reno, Nev., will pay $167,000 to resolve a lawsuit alleging discrimination against persons with disabilities who use assistance animals.

A Reno, Nev. man has been charged with providing material support to terrorism groups in India and Pakistan in order to intimidate the Indian government and to harm persons that were not supporting their cause.

Lowe’s Home Centers, one of the nation’s largest home improvement retailers, has agreed to implement a comprehensive, corporate-wide compliance program at its more than 1,700 stores nationwide to ensure its contractors minimize lead dust from home renovation activities.

Apr 1, 2020

Bruce Schneier discusses current security technology concerns with The Politic's Eric Wallach.

Apr 26, 2020

The secretary of state is preparing an argument that the U.S. remains a participant in the Obama-era nuclear deal, with the goal of extending an arms embargo or destroying the accord.

Apr 1, 2020

Bruce Schneier discusses current security technology concerns with The Politic's Eric Wallach.

Apr 26, 2020

The secretary of state is preparing an argument that the U.S. remains a participant in the Obama-era nuclear deal, with the goal of extending an arms embargo or destroying the accord.

Apr 26, 2020

The secretary of state is preparing an argument that the U.S. remains a participant in the Obama-era nuclear deal, with the goal of extending an arms embargo or destroying the accord.