mice

Vinegar extract ameliorates alcohol-induced liver damage associated with the modulation of gut microbiota in mice

Food Funct., 2020, 11,2898-2909
DOI: 10.1039/C9FO03015H, Paper
Ting Xia, Bo Zhang, Shaopeng Li, Bin Fang, Wenhui Duan, Jin Zhang, Jia Song, Min Wang
Vinegar extract inhibited alcohol-induced ROS generation and inflammation. Vinegar extract modulated gut microbiota and improved intestinal homeostasis, which could be used as a novel gut microbiota manipulator against alcohol-induced liver damage.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Tilapia head glycolipids reduce inflammation by regulating the gut microbiota in dextran sulphate sodium-induced colitis mice

Food Funct., 2020, 11,3245-3255
DOI: 10.1039/D0FO00116C, Paper
Zhipeng Gu, Yujie Zhu, Shuaiming Jiang, Guanghua Xia, Chuan Li, Xueying Zhang, Jiachao Zhang, Xuanri Shen
Tilapia head glycolipids reduce inflammation by regulating the gut microbiota in dextran sulphate sodium-induced colitis mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Low-dose ethanol intake prevents high-fat diet-induced adverse cardiovascular events in mice

Food Funct., 2020, 11,3549-3562
DOI: 10.1039/C9FO02645B, Paper
Junhui Nie, Linel Darrel Ngokana, Jiayuan Kou, Yuchen Zhao, Jiajie Tu, Heng Ji, Peizhu Tan, Tingting Zhao, Yuwei Cao, Zhaojing Wu, Qi Wang, Shuangfeng Ren, Xiuchen Xuan, Hui Huang, Yanze Li, Huan Liang, Xu Gao, Lingyun Zhou
This study aimed to clarify whether low-dose ethanol intake could prevent high-fat diet-induced adverse effects on cardiomyocytes in mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Ptaquiloside from bracken (Pteridium spp.) promotes oral carcinogenesis initiated by HPV16 in transgenic mice

Food Funct., 2020, 11,3298-3305
DOI: 10.1039/D0FO00207K, Paper
Rui M. Gil da Costa, Tiago Neto, Diogo Estêvão, Magda Moutinho, Ana Félix, Rui Medeiros, Carlos Lopes, Margarida M. S. M. Bastos, Paula A. Oliveira
Bracken (Pteridium spp.) is a common weed that is consumed as food especially in Asia, and is suspected of promoting carcinogenesis induced by papillomaviruses in the digestive and urinary systems.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Proteomic landscape of liver tissue in old male mice that are long-term treated with polysaccharides from Sargassum fusiforme

Food Funct., 2020, 11,3632-3644
DOI: 10.1039/D0FO00187B, Paper
Peichao Chen, Ya Zhang, Man Xu, Hongjun Chen, Huixi Zou, Xu Zhang, Haibin Tong, Cuiping You, Mingjiang Wu
The polysaccharides extracted from Sargassum fusiforme delays the aging process via mitochondria-associated anti-oxidation.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

cis 9, trans 11, but not trans 10, cis 12 CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice through activation of GPR120-[Ca2+]i and the MLCK signaling pathway

Food Funct., 2020, 11,3657-3667
DOI: 10.1039/D0FO00376J, Paper
Han Su, Weijie Zhao, Fenglin Zhang, Min Song, Fangfang Liu, Jisong Zheng, Mingfa Ling, Xiaohua Yang, Qiang Yang, Haiwen He, Lin Chen, Xumin Lai, Xiaotong Zhu, Lina Wang, Ping Gao, Gang Shu, Qingyan Jiang, Songbo Wang
In vitro and in vivo studies show that c9, t11-CLA, but not t10, c12-CLA isomer, impairs intestinal epithelial barrier function in IPEC-J2 cells and mice via activation of GPR120-[Ca2+]i and the MLCK pathway.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Hot-water extract of ripened Pu-erh tea attenuates DSS-induced colitis through modulation of the NF-κB and HIF-1α signaling pathways in mice

Food Funct., 2020, 11,3459-3470
DOI: 10.1039/C9FO02803J, Paper
Yina Huang, Liang Qiu, Xuan Mi, Zhihong Zhang, Di Xu, Xueying Tao, Keyu Xing, Qinglong Wu, Hua Wei
There was lots of information on anti-obesity and reduced risk of cardiovascular disease, to our best knowledge, little was known about the prevention of colitis by RPT. We firstly assessed effects of RPT on phenotypic improvements of DSS-induced colitis in mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Gut microbiota mediate the protective effects on endometritis induced by Staphylococcus aureus in mice

Food Funct., 2020, 11,3695-3705
DOI: 10.1039/C9FO02963J, Paper
Xiaoyu Hu, Ruiying Mu, Mingyue Xu, Xin Yuan, Peng Jiang, Jian Guo, Yongguo Cao, Naisheng Zhang, Yunhe Fu
Endometritis, the inflammation of the endometrial lining caused by bacterial pathogens, is associated with reproductive failure.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Flavonoids isolated from loquat (Eriobotrya japonica) leaves inhibit oxidative stress and inflammation induced by cigarette smoke in COPD mice: the role of TRPV1 signaling pathways

Food Funct., 2020, 11,3516-3526
DOI: 10.1039/C9FO02921D, Paper
Tunyu Jian, Jian Chen, Xiaoqin Ding, Han Lv, Jiawei Li, Yuexian Wu, Bingru Ren, Bei Tong, Yuanyuan Zuo, Kelei Su, Weilin Li
Total flavonoids isolated from loquat leaves inhibit inflammation and oxidative stress by regulating TRPV1 and the related pathway in cigarette smoke-induced COPD mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice

Food Funct., 2020, 11,2943-2952
DOI: 10.1039/D0FO00206B, Paper
Open Access
Ana Lemus-Conejo, Elena Grao-Cruces, Rocio Toscano, Lourdes M. Varela, Carmen Claro, Justo Pedroche, Francisco Millan, Maria C. Millan-Linares, Sergio Montserrat-de la Paz
A lupine (Lupinus angustifolious L.) peptide prevents non-alcoholic fatty liver disease in high-fat-diet-induced obese mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Tomato seed oil attenuates hyperlipidemia and modulates gut microbiota in C57BL/6J mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00133C, Paper
Wen-Sen He, Lingling Li, Jiaxin Rui, Junjie Li, Yuying Sun, Dandan Cui, Bin Xu
TSO can significantly improve fatty acid metabolism and cholesterol metabolism, thereby inhibiting obesity and hypercholesterolemia. TSO can favorably modulate the gut microbiota.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Effects of a β-type glycosidic polysaccharide from Flammulina velutipes on anti-inflammation and gut microbiota modulation in colitis mice

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO03017D, Paper
Ruiqiu Zhao, Yang Ji, Xin Chen, Anxiang Su, Gaoxing Ma, Guitang Chen, Qiuhui Hu, Liyan Zhao
Using the Flammulina velutipes polysaccharide (FVP) extracted from our previous study, herein, we investigated the improvement of this β-type glycosidic polysaccharide in alleviating dextran sodium sulfate-induced ulcerative colitis (UC) in mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Effects of polysaccharides from wild morels on immune response and gut microbiota composition in non-treated and cyclophosphamide-treated mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00597E, Paper
Wenyan Huo, Zhengping Feng, Suying Hu, Langjun Cui, Ting Qiao, Lu Dai, Peng Qi, Liguang Zhang, Yu Liu, Junzhi Li
Polysaccharides from wild morels alter gut microbiota, increase the production of SCFAs and promote the proliferation of lymphocytes in mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Jiaogulan tea (Gpostemma pentaphyllum) potentiates the antidiabetic effect of white tea via the AMPK and PI3K pathways in C57BL/6 mice

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00395F, Paper
Xiaoyan Xia, Jing Xu, Xude Wang, Hua Wang, Zhenchuan Lin, Keping Shao, LinLin Fang, Chenning Zhang, Yuqing Zhao
The use of plant-based beverages to interfere with the onset of diabetes may be a promising approach towards type 2 diabetes mellitus (T2DM).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Lactobacillus fermentum CECT5716 prevents renal damage in NZBWF1 mice model of systemic lupus erythematosus

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00578A, Paper
Néstor de la Visitación, Iñaki Robles-Vera, Marta Toral, Francisco O’Valle, Javier Moleon, Manuel Gómez-Guzmán, Miguel Romero, Marcos Duarte, Manuel Sanchez, Rosario Jimenez, Juan Duarte
The aim of this work was to evaluate whether the immune-modulatory bacteria Lactobacillus fermentum CECT5716 (LC40) protects kidneys in a female mouse model of lupus with hypertension. Twenty-week-old NZBWF1 (lupus)...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Hypoglycemic effects and modulation of gut microbiota of diabetic mice by saponin from Polygonatum sibiricum

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00428F, Paper
Jiayuan Luo, Yangyang Chai, Min Zhao, Qingqi Guo, Yihong Bao
Polygonatum sibiricum is a medicinal and homologous plant grown in China. The saponin in Polygonatum sibiricum has shown its good hypoglycemic performance, and it can be developed as functional foods and drugs with hypoglycemic effect.
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The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Effects of compound K, a metabolite of ginsenosides, on memory and cognitive dysfunction in db/db mice involve the inhibition of ER stress and the NLRP3 inflammasome pathway

Food Funct., 2020, Advance Article
DOI: 10.1039/C9FO02602A, Paper
Chu-Wen Li, Min-Zhen Deng, Zhi-Jie Gao, Yuan-Ye Dang, Guo-Dong Zheng, Xiu-Juan Yang, Ying-Xin Chao, Ye-Feng Cai, Xiao-Li Wu
The metabolite of ginsenosides, compound K improves memory and cognitive dysfunction in diabetes mellitus mice.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder containing 1-deoxynojirimycin in a high-fat diet altered the gene expressions related to lipid metabolism and insulin signaling in mice epididymal white adipose tissue

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00271B, Paper
Isabella Supardi Parida, Soo Takasu, Junya Ito, Ryoichi Ikeda, Kenji Yamagishi, Toshiyuki Kimura, Takahiro Eitsuka, Kiyotaka Nakagawa
Supplementation of Bacillus amyloliquefaciens AS385 culture broth powder in high-fat diet restored adiposity, glucose tolerance and insulin sensitivity in mice.
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The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Polysaccharides from Enteromorpha prolifera protect against carbon tetrachloride-induced acute liver injury in mice via activation of Nrf2/HO-1 signaling, and suppression of oxidative stress, inflammation and apoptosis

Food Funct., 2020, Advance Article
DOI: 10.1039/D0FO00575D, Paper
Fuchuan Guo, Xinyun Zhuang, Mengyuan Han, Wenting Lin
EPP protected against hepatic injury induced by CCl4-derived reactive intermediates through the suppression of hepatic oxidative stress, inflammation, and apoptosis.
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The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Effects of gastrodin against carbon tetrachloride induced kidney inflammation and fibrosis in mice associated with the AMPK/Nrf2/HMGB1 pathway

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/D0FO00711K, Paper
J. Q. Ma, Yun-Zhi Sun, Qing-Lei Ming, Zhi-Kai Tian, Yu-Jia Zhang, Chan-Min Liu
Gastrodin (GAS), the main phenolic glycoside extracted from Gastrodia elata Blume, exhibited potential renoprotective properties. Here we examined the protective effects of GAS against carbon tetrachloride (CCl4)-induced kidney inflammation and...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Unsaturated alginate oligosaccharides attenuated obesity-related metabolic abnormalities by modulating gut microbiota in high-fat-diet mice

Food Funct., 2020, Accepted Manuscript
DOI: 10.1039/C9FO02857A, Paper
Shangyong Li, Linna Wang, Bo Liu, Ningning He
Gut microbiota plays an important role in the high-fat diet (HFD)-induced obesity and related metabolic syndrome (MetS). Our previous study has demonstrated that unsaturated alginate oligosaccharides (UAOS) degraded by alginate...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Tumor-targeting peptide functionalized PEG-PLA micelles for efficient drug delivery

Biomater. Sci., 2020, 8,2274-2282
DOI: 10.1039/C9BM02036E, Paper
Yue Cai, Zhuomin Xu, Qi Shuai, Fangtao Zhu, Jiao Xu, Xin Gao, Xuanrong Sun
PEG-PLA micelles are modified with F3 peptides, thus endowing the micelles with active-targeting ability due to the nucleolin-binding ability of the F3 peptides.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Stabilization of indocyanine green dye in polymeric micelles for NIR-II fluorescence imaging and cancer treatment

Biomater. Sci., 2020, 8,2245-2254
DOI: 10.1039/C9BM02010A, Paper
Gil Yeroslavsky, Masakazu Umezawa, Kyohei Okubo, Karina Nigoghossian, Doan Thi Kim Dung, Keiji Miyata, Masao Kamimura, Kohei Soga
Encapsulation of ICG and IR-1061 in PCL–PEG micelles producing agents with increased stability of ICG and tunable PTT and PDT activity. The micelles are also useful for NIR imaging and NIR nanothermometry.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Trastuzumab targeted micellar delivery of docetaxel using dendron–polymer conjugates

Biomater. Sci., 2020, 8,2600-2610
DOI: 10.1039/C9BM01764J, Paper
Burcu Sumer Bolu, Bianka Golba, Amitav Sanyal, Rana Sanyal
Incorporation of a therapeutic antibody into nanosized drug delivery systems can improve their target specificity.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Dual-responsive click-crosslinked micelles designed for enhanced chemotherapy for solid tumors

Biomater. Sci., 2020, 8,2507-2513
DOI: 10.1039/D0BM00078G, Paper
Rong Jin, Jing Sun, Liefu Zhou, Xuelian Guo, Aoneng Cao
Core-crosslinked dual-responsive micelles can be readily constructed from a pair of clickable copolymers and applied for controlled release of anticancer drugs in cancer therapy.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

A transport system based on a quantum dot-modified nanotracer is genetically and developmentally stable in pregnant mice

Biomater. Sci., 2020, Advance Article
DOI: 10.1039/D0BM00311E, Paper
Open Access
Hye Jin Kim, Ji Sun Park, Se Won Yi, Minyeon Go, Hye-Ryun Kim, Su Jin Lee, Jong Min Park, Dong Hyun Cha, Sung Han Shim, Keun-Hong Park
The use of nanoscale materials (NMs) could cause problems such as cytotoxicity, genomic aberration, but the impacts of NM exposure during pregnancy remain uncharacterized in the context of clinical applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Gynura divaricata ameliorates hepatic insulin resistance by modulating insulin signalling, maintaining glycolipid homeostasis and reducing inflammation in type 2 diabetic mice

Toxicol. Res., 2019, 8,928-938
DOI: 10.1039/C9TX00191C, Paper
Xuan Dong, Shu-Xiang Zhao, Bing-Qing Xu, Yu-Qing Zhang
Oral lyophilized powder of Gynura divaricata, an edible medicinal plant, can alleviate both hyperglycaemia and hepatic insulin resistance in type 2 diabetic mice.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Novel evaluation of sevoflurane anesthetic exposure on the testicular germ cells of neonatal male mice

Toxicol. Res., 2019, 8,988-993
DOI: 10.1039/C9TX00193J, Paper
Ali Raza Ebrahim Soltani, Abdolmohammad Kajbafzadeh, Maryam Ezzati, Zahra Ebrahim Soltani, Navid Hosseinifar, Anahid Maleki, Maryam Nezhad Sistani
Inhalatory anesthetics may impact spermatogenesis and sexual behavior.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Mice with a Sertoli cell-specific knockout of the Ctr1 gene exhibit a reduced sensitivity to cisplatin-induced testicular germ cell apoptosis

Toxicol. Res., 2019, 8,972-978
DOI: 10.1039/C9TX00142E, Paper
Open Access
Rashin Ghaffari, John H. Richburg
Exposure to the chemotherapeutic agent cis-diamminedichloroplatinum(II) (cDDP) is well known to instigate acute and prolonged testicular injury in male patients.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Effects of early acoustic stimulation of prepulse inhibition in mice




mice

The influence of amyloid-beta, a major pathological marker in Alzheimer's disease, on molecular cognitive processes of APP+PS1 transgenic mice




mice

Effects of hyperoxia in alzheimers transgenic mice




mice

Dissecting out the contribution of cognitive, social, and physical activities to environmental enrichment's ability to protect Alzheimer's mice against cognitive impairment




mice

Effects of A-beta immunotherapy and Omega-3 fatty acid administration in Alzheimer's transgenic mice




mice

Foraging decisions of nocturnal mice under direct and indirect cues of predation risk




mice

Blood parasite infection in mice from cloud forest and nearby disturbed habitats




mice

Marriage record of Fernandez, Amiceto and Vasquez, Mercedes




mice

Marriage record of Licata, Micele and Fiorito, Rosalia




mice

Marriage record of Ficcarotta, Giuseppe and Miceli, Giuseppina




mice

Marriage record of Miceli, Vincenzo and Cimina, Carmela




mice

Marriage record of Parlapiano, Giovanni and Miceli, Anna




mice

Marriage record of Miceli, Francesco and Pardo, Giuseppa




mice

Immune dimorphism in wild mice of Monteverde, Costa Rica




mice

Possible effects of long-term weather changes and extreme weather events on mice population abundances in Monteverde, Costa Rica




mice

[ASAP] Supramolecular Depolymerization of Nanowires Self-Assembled from Micelles

Macromolecules
DOI: 10.1021/acs.macromol.0c00146




mice

Handbook of In Vivo Chemistry in Mice: From Lab to Living System


 
Provides timely, comprehensive coverage of in vivo chemical reactions within live animals

This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers

Read More...




mice

Unique silica enclosures form on micelles

Dodecahedral ‘silicages’ could carry drugs or diagnostic agents




mice

Noninvasive chemical approach controls deep region of the brain in mice

In mice, surgery-free technique inhibits region implicated in memory formation




mice

Low-dose aspirin improves memory in mice with Alzheimer’s symptoms

Study suggests activating PPAR receptor leads to increased cellular connections in hippocampus




mice

Injections of botulinum conjugate relieves chronic pain in mice

Modified toxin targets and silences nerves that transmit pain, offering a potential nonaddictive alternative to opioids