mice

Cardamonin protects against lipopolysaccharide-induced myocardial contractile dysfunction in mice through Nrf2-regulated mechanism




mice

A novel multidimensional reinforcement task in mice elucidates sex-specific behavioral strategies




mice

Author Correction: <i>Cdkn1a</i> deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation




mice

Tankyrase inhibition ameliorates lipid disorder via suppression of PGC-1α PARylation in <i>db/db</i> mice




mice

Nonnutritive sweetener consumption during pregnancy, adiposity, and adipocyte differentiation in offspring: evidence from humans, mice, and cells




mice

Targeting inflammation in AKI by P2Y14 receptor inhibition in mice




mice

Meet the singing mice of the cloud forests (videos)

When two male Alston's singing mice meet, they sing an operatic duet that researchers say offers clues about our own speech.




mice

Nanoparticle Effectively Vaccinates Mice Against Dengue Fever

New type of nanoparticle developed by scientists effectively vaccinated mice against dengue virus. The findings of the study published in PLOS Neglected Tropical Diseases.




mice

Stem Cells Help Reverse Diabetes in Mice

CRISPR-Cas9, the gene editing tool helps correct a genetic defect that had caused Wolfram syndrome, a rare, genetic form of insulin-dependent diabetes.




mice

Acai Berry Derivatives Treat Malaria in Mice

Acai berry extracts can reduce parasites in the blood and prolong the survival of malarial mice, according to the study published in iACS Omega/i.




mice

Horrified passer-by films mice scuttling across the floor of a Pret a Manger restaurant in London

David Nassim, 51, recorded 'at least five' rodents scurrying around the closed Pret a Manger restaurant in Leicester Square on Halloween night.




mice

Tricks To Get Rid Of Mice And Spider

Most women are scared of mice and spiders and despise the presence of the same in the house. The origin and reason for their fear is indeed debatable. However, their hatred for the presence of mice and spiders in the house




mice

MICE tourism

MICE tourism




mice

Hydrogen-bonded supramolecular micelle-mediated drug delivery enhances the efficacy and safety of cancer chemotherapy

Polym. Chem., 2020, 11,2791-2798
DOI: 10.1039/D0PY00082E, Paper
Chih-Chia Cheng, Ya-Ting Sun, Ai-Wei Lee, Shan-You Huang, Wen-Lu Fan, Yu-Hsuan Chiao, Chih-Wei Chiu, Juin-Yih Lai
Multiple hydrogen-bonded supramolecular polymers tend to form stable spherical micelles with oppositely charged anticancer drugs in biological environments, which improves cellular drug uptake and more effectively induces apoptosis in cancer cells.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

310 nm UV-LED Attenuates Imiquimod-Induced Psoriasis-like Skin Lesions in C57BL/6 Mice and Inhibits IL-22-Induced STAT3 Expression in HaCaT Cells

Photochem. Photobiol. Sci., 2020, Accepted Manuscript
DOI: 10.1039/C9PP00444K, Paper
Tae-Rin Kwon, Sung-Eun Lee, Jong-Hwan Kim, Yu Na Jang, Su-Young Kim, Seok Kyun Mun, Chan Woong Kim, Jungtae Na, Beom Joon Kim
Ultraviolet light-emitting diodes (UV-LEDs) are a novel light source for phototherapy. This study aimed to evaluate the therapeutic effects of UV-LEDs on psoriasis. Importantly, 310 nm UV-LEDs have not been...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Effects of lignin, cellulose, hemicellulose, sucrose and monosaccharide carbohydrates on soybean physical stem strength and yield in intercropping

Photochem. Photobiol. Sci., 2020, 19,462-472
DOI: 10.1039/C9PP00369J, Paper
Sajad Hussain, Ting Liu, Nasir Iqbal, Marian Brestic, Ting Pang, Maryam Mumtaz, Iram Shafiq, Shuxian Li, Li Wang, Yang Gao, Aaqil Khan, Irshan Ahmad, Suleyman I. Allakhverdiev, Weiguo Liu, Wenyu Yang
To the best of our knowledge, for the first time our research examines a role of secondary cell wall components in lodging resistance and their interaction with yield under intercropping.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Development of mucoadhesive cationic polypeptide micelles for sustained cabozantinib release and inhibition of corneal neovascularization

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00874E, Paper
Haijie Han, Qichuan Yin, Xiajing Tang, Xiaoning Yu, Qiang Gao, Yelei Tang, Andrzej Grzybowski, Ke Yao, Jian Ji, Xingchao Shentu
Corneal neovascularization (CNV) is one of the leading risk factors for vision loss. Anti-angiogenic drugs can theoretically be extended to the treatment of CNV. However, the application of these drugs...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Multi-Stimuli Responsive Polymeric Prodrug Micelles for Combined Chemotherapy and Photodynamic Therapy

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00539H, Paper
Cheng Hu, Weihua Zhuang, Tao Yu, Liang Chen, Zhen Liang, Gaocan Li, Yunbing Wang
Nowadays, cancer therapy faces severe challenges on boosting therapeutic efficiency and reducing the side effects of drugs. To overcome these challenges, herein multifunctional polymeric prodrug micelles with combining chemotherapy and...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Transforming micelles into mixed micelles: a promising approach to tune the catalytic performance of imidazolium-based surface active ionic liquids toward degradation of rhodamine B

Phys. Chem. Chem. Phys., 2020, Advance Article
DOI: 10.1039/C9CP07040K, Paper
Fayaz Ahmed Butt, Parvaiz Ahmad Bhat, Sajad Ahmad Bhat, Nusrat Rashid, Mudasir Ahmad Rather, Sarwar Ahmad Pandit, Pravin P. Ingole, Ghulam Mohammad Rather, Mohsin Ahmad Bhat
Incorporating nonionic Brij56 into cationic DDMIMCl (SAIL) micelles significantly enhances catalytic performance of SAIL toward reductive degradation of rhodamine B, a potential carcinogenic dye extensively used in multiple industrial applications.
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Different submicellar solubilization mechanisms revealed by 1H NMR and 2D diffusion ordered spectroscopy (DOSY)

Phys. Chem. Chem. Phys., 2020, Advance Article
DOI: 10.1039/D0CP00429D, Paper
Mengjian Wu, Zhaoxia Wu, Shangwu Ding, Zhong Chen, Xiaohong Cui
Different submicellar solubilization mechanisms of two systems, Triton X-100/tetradecane and sodium dodecyl sulfate (SDS)/butyl methacrylate, are revealed on the molecular scale by 1H NMR spectroscopy and 2D diffusion ordered spectroscopy (DOSY).
To cite this article before page numbers are assigned, use the DOI form of citation above.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Noncovalent structural locking of thermoresponsive polyion complex micelles, nanowires, and vesicles via polymerization-induced electrostatic self-assembly using an arginine-like monomer

Chem. Commun., 2020, 56,4954-4957
DOI: 10.1039/D0CC00427H, Communication
Qingqing Zhao, Qizhou Liu, Chao Li, Lei Cao, Lei Ma, Xiyu Wang, Yuanli Cai
The noncovalent locking of nanostructured thermoresponsive polyion complexes can be achieved via polymerization-induced electrostatic self-assembly (PIESA) using an arginine-like cationic monomer.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Novel phthalocyanine-based micelles/PNIPAM composite hydrogels: spatial/temporal-controlled drug release triggered by NIR laser irradiation

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ01882A, Letter
Tao Jia, Lu Li, Enna Ha, Zheng Qu, Lei Shi, Tiedong Sun, Shengnan Tan, Wancheng Zhao
Near-infrared (NIR) light-responsive hydrogels hold significant potential for biomedical application, especially in remote-controlled release of anticancer drugs. Herein we report a novel NIR light responsive composite hydrogel system that undergoes...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

[ASAP] Systems Toxicology Approaches Reveal the Mechanisms of Hepatotoxicity Induced by Diosbulbin B in Male Mice

Chemical Research in Toxicology
DOI: 10.1021/acs.chemrestox.9b00503




mice

[ASAP] Quantitative Prediction of the Structure and Viscosity of Aqueous Micellar Solutions of Ionic Surfactants: A Combined Approach Based on Coarse-Grained MARTINI Simulations Followed by Reverse-Mapped All-Atom Molecular Dynamics Simulations

Journal of Chemical Theory and Computation
DOI: 10.1021/acs.jctc.0c00229




mice

[ASAP] Direct Observation of Micelle Fragmentation via In Situ Liquid-Phase Transmission Electron Microscopy

ACS Macro Letters
DOI: 10.1021/acsmacrolett.0c00273




mice

[ASAP] A6 Peptide-Tagged Core-Disulfide-Cross-Linked Micelles for Targeted Delivery of Proteasome Inhibitor Carfilzomib to Multiple Myeloma In Vivo

Biomacromolecules
DOI: 10.1021/acs.biomac.9b01790




mice

[ASAP] Self-Assembly of Copolymer Micelles: Higher-Level Assembly for Constructing Hierarchical Structure

Chemical Reviews
DOI: 10.1021/acs.chemrev.9b00774




mice

[ASAP] Flow-Induced Micellar Morphological Transformation in Microfluidic Chips under Nonequilibrium State: From Aggregates to Spherical Micelles

Langmuir
DOI: 10.1021/acs.langmuir.0c00836




mice

Converging clinical and engineering research on neurorehabilitation III: proceedings of the 4th International Conference on NeuroRehabilitation (ICNR2018), October 16-20, 2018, Pisa, Italy / editors, Lorenzo Masia, Silvestro Micera, Metin Akay and Jos

Online Resource




mice

Metal-free carbon monoxide-releasing micelles undergo tandem photochemical reactions for cutaneous wound healing

Chem. Sci., 2020, 11,4499-4507
DOI: 10.1039/D0SC00135J, Edge Article
Open Access
Jian Cheng, Bin Zheng, Sheng Cheng, Guoying Zhang, Jinming Hu
Metal-free carbon monoxide-releasing polymers (CORPs) are synthesized via a direct polymerization approach, exhibiting not only improved stability but also accelerated wound healing performance as compared to CORM-3.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Mice in Space! A special Carolina Science Cafe

Dr. Ted Bateman will be talking about the research project he has aboard the last space shuttle mission and how it applies to cancer studies here on Earth.




mice

Bis(ethylmaltolato)oxidovanadium(IV) inhibited the pathogenesis of Alzheimer's disease in triple transgenic model mice

Metallomics, 2020, 12,474-490
DOI: 10.1039/C9MT00271E, Paper
Zhijun He, Shuangxue Han, Chong Wu, Lina Liu, Huazhang Zhu, Ang Liu, Qiying Lu, Jingqiang Huang, Xiubo Du, Nan Li, Qinguo Xie, Lu Wan, Jiazuan Ni, Lingling Chen, Xiaogai Yang, Qiong Liu
BEOV activates PPARγ to affect JAK2/STAT3/SOCS1 signaling and eventually prevents Aβ generation. Meanwhile, BEOV inactivates PTP1B to affect PI3K/Akt/GSK3β signaling and finally reduces tau hyperphosphorylation.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Correction: Bis(ethylmaltolato)oxidovanadium(IV) inhibited the pathogenesis of Alzheimer's disease in triple transgenic model mice

Metallomics, 2020, 12,631-631
DOI: 10.1039/D0MT90008G, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Zhijun He, Shuangxue Han, Chong Wu, Lina Liu, Huazhang Zhu, Ang Liu, Qiying Lu, Jingqiang Huang, Xiubo Du, Nan Li, Qingguo Xie, Lu Wan, Jiazuan Ni, Lingling Chen, Xiaogai Yang, Qiong Liu
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Podcast: Sizing up a baby dino, jolting dead brains, and dirty mice

Online news editor David Grimm shares stories on a possibledebunking of a popular brain stimulation technique, using “dirty” mice in the lab to simulate the human immune system, and how South American monkeys’ earliest ancestors used rafts to get to Central America.   Kristi Curry Rogers joins host Sarah Crespi to discuss insights into dinosaur growth patterns from the bones of a baby titanosaur found in Madagascar.  Read the research.   [Image: K. Curry Rogers et al./Science]




mice

Podcast: How mice mess up reproducibility, new support for an RNA world, and giving cash away wisely

News stories on a humanmade RNA copier that bolsters ideas about early life on Earth, the downfall of a pre-Columbian empire, and how a bit of cash at the right time can keep you off the streets, with Jessica Boddy.   From the magazine This story combines two things we seem to talk about a lot on the podcast: reproducibility and the microbiome. The big question we’re going to take on is how reproducible are mouse studies when their microbiomes aren’t taken into account? Staff writer Kelly Servick is here to talk about what promises to be a long battle with mouse-dwelling bugs.   [Image: Annedde/iStockphoto; Music: Jeffrey Cook]




mice

Podcast: Explaining menopause in killer whales, triggering killer mice, and the role of chromosome number in cancer immunotherapy

This week, we chat about a surprising reason why killer whales undergo menopause, flipping a kill switch in mice with lasers, and Fukushima residents who measured their own radiation exposure[link tk], with Online News Editor Catherine Matacic. Plus, Science’s Alexa Billow talks to Stephen Elledge about the relationship between chromosomal abnormalities in tumors and immunotherapy for cancer.   Listen to previous podcasts.   [Image: Copyright Kenneth Balcomb Center for Whale Research; Music: Jeffrey Cook]




mice

A possible cause for severe morning sickness, and linking mouse moms’ caretaking to brain changes in baby mice

Researchers are converging on which genes are linked to morning sickness—the nausea and vomiting associated with pregnancy—and the more severe form: hyperemesis gravidarum (HG). And once we know what those genes are—can we help pregnant women feel better? News intern Roni Dengler joins Sarah Crespi to talk about a new study that suggests a protein already flagged for its role in cancer-related nausea may also be behind HG. In a second segment, Tracy Bedrosian of the Neurotechnology Innovations Translator talks about how the amount of time spent being licked by mom might be linked to changes in the genetic code of hippocampal neurons in mice pups. Could these types of genomic changes be a new type of plasticity in the brain? This week’s episode was edited by Podigy. Listen to previous podcasts. [Image: Jacob Bøtter/Flickr; Music: Jeffrey Cook]




mice

Children sue the U.S. government over climate change, and how mice inherit their gut microbes

A group of children is suing the U.S. government—claiming their rights to life, liberty, and property are under threat from climate change thanks to government policies that have encouraged the use and extraction of fossil fuels. Host Meagan Cantwell interviews news writer Julia Rosen on the ins and outs of the suit and what it could mean if the kids win the day.    Also this week, host Sarah Crespi talks with Andrew Moeller of Cornell University about his work tracing the gut microbes inherited through 10 generations of mice. It turns out the fidelity is quite high—you can still tell mice lineages apart by their gut microbes after 10 generations. And horizontally transmitted microbes, those that jump from one mouse line to another through exposure to common spaces or handlers, were more likely than inherited bacteria to be pathogenic and were often linked to illnesses in people. This week’s episode was edited by Podigy. Download a transcript of this episode (PDF) Listen to previous podcasts. About the Science Podcast [Image: Bob Dass/Flickr; Music: Jeffrey Cook] 




mice

How COVID-19 disease models shape shutdowns, and detecting emotions in mice

On this week’s show, Contributing Correspondent Kai Kupferschmidt talks with host Sarah Crespi about modeling coronavirus spread and the role of forecasts in national lockdowns and other pandemic policies. They also talk about the launch of a global trial of promising treatments. See all of our News coverage of the pandemic here. See all of our Research and Editorials here. Also this week, Nadine Gogolla, research group leader at the Max Planck Institute of Neurobiology, talks with Sarah about linking the facial expressions of mice to their emotional states using machine learning. This week’s episode was produced with help from Podigy. Listen to previous podcasts. About the Science Podcast Download a transcript (PDF)




mice

NMR-based plasma metabonomics in hyperlipidemia mice

Anal. Methods, 2020, 12,1995-2001
DOI: 10.1039/D0AY00487A, Paper
Yun Li, Xiu-ju Zhao
Hyperlipidemia dynamics need to be elucidated.
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Impact of wormlike micelles on nano and macroscopic structure of TEMPO-oxidized cellulose nanofibrils hydrogels

Soft Matter, 2020, Accepted Manuscript
DOI: 10.1039/D0SM00135J, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Marcelo A. da Silva, Vincenzo Calabrese, Julien Schmitt, Kazi M. Zakir Hossain, Saffron J Bryant, Najet Mahmoudi, Janet L Scott, Karen J Edler
In this work, we investigated the effect of adding surfactant mixtures on the rheological properties of TEMPO-oxidized cellulose nanofibrils (OCNF) saline dispersions. Three surfactant mixtures were studied: cocamidopropyl betaine (CAPB)/sodium...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Classical and Non-Classical Melatonin Receptor Agonist-Directed Micellization of Bipyridinium-Based Supramolecular Amphiphiles in Water

Soft Matter, 2020, Accepted Manuscript
DOI: 10.1039/D0SM00424C, Paper
Zhimin Sun, Lihui Xi, Kai Zheng, Zhao Zhang, Kim Baldridge, Mark Anthony Olson
The addition of molecular recognition units into structures of amphiphiles is a means by which soft matter capable of undergoing template-directed micellization can be obtained. These supramolecular amphiphiles can bind...
The content of this RSS Feed (c) The Royal Society of Chemistry




mice

Handbook of In Vivo Chemistry in Mice: From Lab to Living System


 
Provides timely, comprehensive coverage of in vivo chemical reactions within live animals

This handbook summarizes the interdisciplinary expertise of both chemists and biologists performing in vivo chemical reactions within live animals. By comparing and contrasting currently available chemical and biological techniques, it serves not just as a collection of the pioneering work done in animal-based studies, but also as a technical guide to help readers

Read More...




mice

[ASAP] 3'-Hydroxypterostilbene Potently Alleviates Obesity Exacerbated Colitis in Mice

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.0c01782




mice

[ASAP] Eicosapentaenoic Acid-Enriched Phosphoethanolamine Plasmalogens Alleviated Atherosclerosis by Remodeling Gut Microbiota to Regulate Bile Acid Metabolism in LDLR<sup>–/–</sup> Mice

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.9b08296




mice

[ASAP] Changes in microRNAs Expression Profile of Mimetic Aging Mice Treated with Melanin from <italic toggle="yes">Sepiella japonica</italic> Ink

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.0c00291




mice

[ASAP] High <sc>l</sc>-Carnitine Ingestion Impairs Liver Function by Disordering Gut Bacteria Composition in Mice

Journal of Agricultural and Food Chemistry
DOI: 10.1021/acs.jafc.9b08313




mice

Bacteria producing checkpoint inhibitors shrink tumors in mice

After being injected into tumors, the bacteria self-destruct to release their therapeutic cargo




mice

[ASAP] Nerve Growth Factor Gene Delivery across the Blood–Brain Barrier to Reduce Beta Amyloid Accumulation in AD Mice

Molecular Pharmaceutics
DOI: 10.1021/acs.molpharmaceut.0c00218




mice

Supplementation of nano-bubble curcumin extract improves gut microbiota composition and exercise performance in mice

Food Funct., 2020, 11,3574-3584
DOI: 10.1039/C9FO02487E, Paper
Yi-Ming Chen, Wan-Chun Chiu, Yen-Shuo Chiu, Tong Li, Hsin-Ching Sung, Chien-Yu Hsiao
NCE supplementation was able to modulate the gut microbiota increased the Lactobacillus genus.
The content of this RSS Feed (c) The Royal Society of Chemistry