Hopson became the interim superintendent in Shelby County, Tenn., in 2013 after the Memphis City School system merged with Shelby County schools. That merger then led six suburban communities to break away from the merged school system to form their own school districts.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

CNA Staff, May 7, 2020 / 11:50 am (CNA).- Bishop Kevin Rhoades of Fort Wayne-South Bend said Thursday that the alleged visions and revelations known as “Our Lady of America” cannot be said to be of supernatural origin, and that public devotion to “Our Lady of America” is not permitted for Catholics.

Sister Mary Ephrem Neuzil of the Congregation of the Sisters of the Most Precious Blood of Jesus began having what seemed like mystical experiences, including inner locutions and visions of the spirit, around 1938. She revealed these to her confessor in 1948, and they became a devotion to Mary as “Our Lady of America” in 1954.

Sr. Neuzil said the Blessed Virgin began appearing to her in 1956 in Rome City, Ind., about 40 miles northwest of Fort Wayne.

The alleged visions and messages from Mary and from St. Joseph continued through 1959, in a number of locations. After 1959, she said Our Lady communicated with her primarily by locutions, until her death in 2000.

Bishop Rhoades agreed in 2017 to conduct an investigation into the alleged apparitions. The bishop issued to other U.S. bishops a statement May 7 on the investigation, which was obtained by CNA, along with a July 2019 decree on the matter.

In the statement, Rhoades said that Sr. Neuzil “was honest, morally upright, psychologically balanced, devoted to religious life and without guile.” He added that she had “signs of imperfection, but no evidence that she was the perpetrator of a hoax or the victim of delusion.”

“What she communicated about her alleged experiences, she believed to be true, and her communication of those experiences are filled with humility and forthrightness,” he added.

The bishop noted there are numerous reports of conversions, spiritual refreshments and consolations, and even some physical healings related to the alleged apparition. He added, though, that “we cannot conclude that any of these events are conclusive enough to warrant certification as miracles. It seems likely that in such personal contexts of faith and prayer, God's graces were received.”

While “much of what is expressed” in the alleged revelations “does not contain any doctrinal error,” Bishop Rhoades wrote that there is a claim of St. Joseph as “'co-redeemer' with Christ for the salvation of the world … which has never been expressed as Catholic doctrine and must be seen as an error.”

He reported that Sr. Neuzil's spiritual director, Archbishop Paul Leibold, wrote in 1970 that he was unable to make a judgement on the supernatural nature of her visions, and that while he had helped her in promoting them as a “private devotion,” he had never acted “to promote her devotion publicly.”

“Looking at the nature and quality of the experiences themselves, we find that they are more to be described as subjective inner religious experiences rather than objective external visions and revelations,” Bishop Rhoades wrote.

“Thus, while it may be said that there is possibly an authenticity to Sister Neuzil's subjective religious experience, we do not find evidence pointing to her experience as being in the category of objective private revelation.”

The bishop and his investigatory commission found that “her experiences were of a type where her own imagination and intellect were involved in the formation of the events. It seems that these were authentically graced moments, even perhaps of a spiritual quality beyond what most people experience, but subjective ones in which her own imagination and intellect were constitutively engaged, putting form to inner spiritual movements. However, we do not find evidence that these were objective visions and revelations of the type seen at Guadalupe, Fatima and Lourdes.”

Bishop Rhoades' judgement was issued in the July 29, 2019 decree, which was signed also by Fr. Mark Gurtner, then-chancellor of the Diocese of Fort Wayne-South Bend.

The five other bishops where the purported visions were said to have occurred – Archbishop Dennis Schnurr of Cincinnati, Archbishop Allen Vigneron of Detroit, Bishop Timothy Doherty of Lafayette in Indiana, Bishop Thomas Olmsted of Phoenix, and Bishop Daneil Thomas of Toledo in Ohio – each concur with Bishop Rhoades' findings and conclusions.

The six bishops had in 2017 asked the US bishops' conference to investigate the alleged apparitions, considering that inquiries were being received about the alleged apparition and its purported request for a procession of the nation's bishops and that a statue of Our Lady of America be placed in the Basilica of the National Shrine of the Immaculate Conception.

The Congregation for the Doctrine of the Faith advised that it be conducted by one of the bishops, and Bishop Rhoades agreed to do so.

He received documentation of Sr. Neuzil's correspondence the following year, and he conducted the evaluation with a commission of theological and canonical experts. They also gathered personal interviews with witnesses who knew Sr. Neuzil.

The procedure for the investigation was carried out in accordance with the Congregation for the Doctrine of the Faith's 1978 "Norms regarding the manner of proceeding in the discernment of presumed apparitions or revelations."

Some bishops have permitted the public display of statues of Our Lady of America, and then-Msgr. Liebold had given an imprimatur to a prayer attached to the devotion in 1963.

The six bishops wrote May 7 that “given this history of prayers and religious articles being given approval by competent ecclesiastical authority, the use of such prayers religious articles may continue as a matter of private devotion, but not as a public devotion of the Church.”

“Indeed, such private devotion would be consistent with the history of the United States of America being dedicated to Our Lady,” they added.

However, “such private devotion should in no way imply approval or acceptance of purported revelations, visions, or locutions attributed to Sister Mary Ephrem (Mildred) Neuzil other than as her own subjective inner religious experiences.”

A spokesperson for the Diocese of Fort Wayne-South Bend told CNA that “the conclusion of Bishop Rhoades and the other five bishops pertains to the entire Church. The same would have been true if the decision were in the affirmative.”

 

CNA Staff, Apr 30, 2020 / 05:00 am (CNA).- The bishops of England and Wales have urged parishes to help domestic abuse victims after a surge in requests for aid during the coronavirus crisis. 

Since the lockdown began in the U.K. March 23 there has been a 49% increase in calls and online pleas for assistance related to domestic abuse, the bishops said in a statement April 29. 

Bishop John Sherrington, chairman of the bishops’ domestic abuse group, said: “Catholic parishes can play an important role in fighting the scourge of domestic abuse, especially during the COVID-19 pandemic where we are seeing some shocking statistics from leading domestic abuse organisations.”

Guidance provided by the bishops’ domestic abuse group encourages pastors to raise the issue of domestic violence during livestreamed Masses and in homilies published on parish websites. 

The group also asks parishes to establish local domestic abuse support groups. Teams of volunteers should keep in regular contact with vulnerable parishioners, and collect and deliver donations to those living in refuges and other safe locations, the group advises.

It adds that team leaders ought to be “in a non-vulnerable COVID-19 category, and not living with any vulnerable people.” They should also have been checked by the Disclosure and Barring Service, which informs employers about applicants’ criminal records.

“Every local situation will differ and so our new guidance is designed to be used as an introduction to start a local project,” Bishop Sherrington said. “I hope that Catholics and parishes will be inspired to take this up in their local area.”

“Violence of this kind should never be tolerated or justified. It is an offence against the dignity of the human person.”
 

London, England, May 1, 2020 / 05:00 am (CNA).- The metropolitan archbishops of England and Wales acknowledged the pain of Catholics who cannot receive the sacraments because of the coronavirus lockdown in a message issued Friday. 

In the message, entitled “A People who Hope in Christ”, published May 1, the archbishops said that while livestreamed Masses nourished faith, they were no substitute for public liturgies.

“None of us would want to be in the situation in which we find ourselves,” they wrote. “While the livestreaming of the Mass and other devotions is playing an important part in maintaining the life of faith, there is no substitute for Catholics being able to physically attend and participate in the celebration of the Mass and the other sacraments.”

Writing on behalf of the Catholic bishops of England and Wales, the five archbishops continued: “Our faith is expressed powerfully and beautifully though ‘seeing, touching, and tasting.’ We know that every bishop and every priest recognizes the pain of Catholics who, at present, cannot pray in church or receive the sacraments. This weighs heavily on our hearts.” 

“We are deeply moved by the Eucharistic yearning expressed by so many members of the faithful. We thank you sincerely for your love for the Lord Jesus, present in the sacraments and supremely so in the Holy Sacrifice of the Mass.” 

“The bishops and priests of every diocese are remembering you and your loved ones at Mass each day in our churches as we pray ‘in hope of health and well-being.’ We thank our priests for this faithfulness to their calling.”

Nevertheless, the archbishops said, the Catholic community had to play its part in preserving life and seeking the common good amid the pandemic. Restrictions on public liturgies would therefore have to remain in place until they are lifted by the government.

The U.K. is among the countries worst affected by the pandemic. With a population of 67 million, the U.K has had more than 172,000 documented coronavirus cases and 26,700 deaths as of May 1, according to Johns Hopkins University Coronavirus Resource Center.

The archbishops emphasized that Church officials were in talks with public health agencies and the government about the reopening of churches, which were closed March 24. 

“As the government’s restrictions are relaxed step by step, we look forward to opening our churches and resuming our liturgical, spiritual, catechetical and pastoral life step by step,” they said. 

“This will also be of service to those beyond the Catholic Church who depend on our charitable activity and outreach through which much goodness is shared by so many volunteers from our communities...”

“Together with Catholics across England and Wales, we desire the opening of our churches and access to the sacraments. Until then, we are continuing to pray and prepare.”

The message was signed by Cardinal Vincent Nichols of Westminster, Archbishop Malcolm McMahon of Liverpool, Archbishop Bernard Longley of Birmingham, Archbishop George Stack of Cardiff and Archbishop John Wilson of Southwark.

The archbishops concluded: “May the peace of the risen Lord reign in our hearts and homes as we look forward to the day we can enter church again and gather around the altar to offer together the Sacrifice of Praise.”

CNA Staff, May 5, 2020 / 10:00 am (CNA).- Poland’s bishops have intervened in a debate about whether presidential elections scheduled for May 10 should go ahead despite a nationwide lockdown.

A statement from the permanent council of the Polish bishops’ conference April 27 urged politicians to work together to ensure that the election would be regarded as legitimate by all sides. 

It said: “We appeal to the consciences of those responsible for the common good of our homeland, both those in power and the opposition, to work out a common position on the presidential elections in this extraordinary situation.” 

Poland’s ruling coalition, led by the Law and Justice (PiS) party, has rejected calls to postpone the election, due to take place this Sunday. 

The state began introducing lockdown measures March 10, which it is now starting to lift. Poland, which has a population of almost 38 million, had 14,242 documented coronavirus cases and 700 deaths as of May 5, according to Johns Hopkins University Coronavirus Resource Center.

The Polish Senate began debating legislation May 5 that would allow the election to be held by postal vote, rather than at polling stations, due to the pandemic. 

The Sejm, the lower chamber of the Polish parliament, will have the final say on the legislation. 

The bishops called on lawmakers to resolve the issue while upholding the principles of Poland’s constitution. They emphasized that they were not seeking to engage in “purely political disputes over the form or timing of election, let alone to advocate this or that solution.”

The bishops’ permanent council said: “We encourage dialogue between the parties to seek solutions that would not raise legal doubts and suspicion, not only of a violation of the current constitutional order but also of the principles of free and fair elections adopted in a democratic society.”

“We ask that, guided by the best will, they would seek in their actions the common good, which today is expressed both by the life, health and social existence of Poles, as well as broad social trust in the electoral procedures of a democratic state jointly developed over the years.”

The bishops continued: “In this difficult situation that we are experiencing, we should take care to cultivate a mature democracy, protect the nation of laws, building -- despite differences -- a culture of solidarity, also in the political sphere.”

If parliament approves the postal vote, the government could delay the vote to either May 17 or May 23 to allow more preparation time, according to Reuters. 

Opinion polls suggest the incumbent President Andrzej Duda, a PiS ally, would be re-elected by a significant margin if the vote were held soon. 

Bishops’ conference president Archbishop Stanisław Gądecki entrusted Poland to the Most Sacred Heart of Jesus and to Our Lady, Queen of Poland, at Jasna Góra Monastery in Częstochowa May 3.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

An educator's experience teaching math is important, but performance on math-content-certification tests is the best predictor of how well a teacher's students will perform in early algebra, finds a new study by the Regional Educational Laboratory Central at Marzano Research.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

An educator's experience teaching math is important, but performance on math-content-certification tests is the best predictor of how well a teacher's students will perform in early algebra, finds a new study by the Regional Educational Laboratory Central at Marzano Research.

CNA Staff, Mar 31, 2020 / 06:01 pm (CNA).- Local media in Nicaragua are reporting that despite the nation’s bishops’ conference suspending Mass and prohibiting large gatherings, the mayor of Granada is going ahead with an annual pilgrimage that the bishops had canceled.

For more than 150 years, Catholics in Nicaragua have venerated an image of Jesus del Rescate (Jesus of the Rescue) in Popoyuapa, near the city of Rivas. The image represents the crowning of thorns and the flogging of Christ.

Normally there is an annual pilgrimage to the image, which pilgrims make by wagon and on foot, during the "Week of Sorrows" that marks "the final stretch" of the time of Lent, according to ACI Prensa, CNA’s Spanish language news partner.

However, the bishops have said that this year it will not be possible to carry it out in the traditional way, given the coronavirus (COVID-19) pandemic.

Nevertheless, Julia Mena, mayor of Granada, has organized and funded a group of pilgrims to do the pilgrimage, providing them with food and personal hygiene supplies, according to the Nicaraguan news website Confidencial. The priest at the shrine told Confidencial that he has “no plans to receive the pilgrimage.”

The Nicaraguan Episcopal Conference has not commented publicly on the matter.

Nicaragua has five confirmed cases of COVID-19. The government has not yet decreed any kind of alert or emergency regarding the pandemic, nor has it ordered a suspension of classes, Confidencial reports.

The country’s Ministry of Health has maintained that the internal movements of travelers arriving from countries with outbreaks of coronavirus would not be restricted, La Prensa reports.

President Daniel Ortega has been president of Nicaragua since 2007, and oversaw the abolition of presidential term limits in 2014.

The Church had suggested that elections, which are not scheduled until 2021, be held this year, but Ortega has ruled this out.

Ortega was a leader in the Sandinista National Liberation Front, which had ousted the Somoza dictatorship in 1979 and fought US-backed right-wing counterrevolutionaries during the 1980s. Ortega was also leader of Nicaragua from 1979 to 1990.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

CNA Staff, Apr 24, 2020 / 11:31 am (CNA).- The bishops of Togo called for peace and respect for the rights of citizens after the violent arrest of an opposition leader from his home on Tuesday.

“[E]very citizen has the right and duty to express his/her disapproval in the face of manifest injustice and oppression,” the Catholic bishops of Togo said in a statement, according to English Africa Service.

“The physical violence and other inhuman and degrading treatment inflicted on citizens on this occasion is, therefore, a negation of their rights and freedoms…the Conference of Bishops denounces and condemns them, and calls on authorities to exercise restraint.”

In their statement, the bishops said they were dismayed to learn that opposition leader Agbeyome Kodjo had been arrested at his home this week, “in circumstances of brutality and violence perpetrated by the Defence and Security Forces.”

News reports indicated that police had broken into Kodjo’s home to arrest him for failing to appear before the nation’s intelligence police force. The opposition leader previously served as prime minister of the country, but his diplomatic immunity was removed last month by Parliament.

Kodjo, who heads the Patriotic Movement for Democracy and Development, came in a distant second to incumbent President Faure Gnassingbé Eyadéma in the nation’s February presidential elections.

Kodjo called the results a farce and declared himself the rightful president of the country. He said his calculations showed that he had received some 60% of the nation’s votes, while official tallies put him at about 18%.

Gnassingbé has been president of Togo since 2005 and is entering his fourth term. His father previously ruled the country after a 1967 coup.

Togo has seen political instability and widespread poverty in recent years. Protests in 2017 called for the resignation of Gnassingbé and resulted in harsh crackdowns.

Last month, 90-year-old Archbishop emeritus Philippe Fanoko Kpodzro of Lome was placed under house arrest briefly, after he encouraged protests following the presidential election.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

By Bishop W. Shawn McKnight

The November General Assembly of Bishops in Baltimore was a difficult but perhaps unavoidable experience for us to move forward as a Church. I was very disappointed to learn that the Holy See found it necessary to insist that the USCCB not take action at this time on the proposals presented by our conference leadership. My frustration, shared with many other people, is this: We have known about the scandal of Archbishop McCarrick since the end of June, and our Church must take immediate, decisive and substantive action in light of the deep wound the scandal has caused.

I am not so concerned about the time it is taking to punish the perpetrator. Pope Francis immediately required the Archbishop to resign from the College of Cardinals when Cardinal Dolan announced the New York review board found a credible and substantiated allegation of sexual abuse of a minor against him. I’m okay with the fact that further penalties (which could include McCarrick’s return to the lay state) will take more time for a complete canonical process. McCarrick isn’t going anywhere and he is already living a life of imposed prayer and penance.

But much more is needed than simply meting out a just punishment. How could his rise to such an influential position in the Church have happened? I am concerned how the national conference of bishops and the Holy See answer that question. An internal investigation of the McCarrick scandal without the use of competent and qualified lay investigators will hardly be considered transparent and credible. We need and must utilize the best and brightest people to do a top-notch investigation and study of the problem. Archbishop Charles Scicluna of Malta is the most qualified Catholic clergy to lead such an investigation, but without knowing that his collaborators include competent laity, the public may not perceive his eventual report as independent and complete enough to be believed.

At the time of this writing, there has not been one bishop, archbishop or cardinal in either the Holy See or the United States who has come forward on his own to repent publicly of his sins of omission or commission with regard to Archbishop McCarrick’s series of promotions over decades. Please, be men, not cowards, and come clean on your own! There doesn’t have to be a formal and long, drawn out investigation for a bishop to exercise a little compunction and concern for the well-being of the whole Church. An independent and transparent investigation is all the more necessary when culpable hierarchs exhibit an incapacity to do the right thing on their own.

The laity are the only ones who can keep the hierarchy accountable and get us out of the mess we bishops got ourselves into. My singular focus throughout the Baltimore meeting was to advocate and push for greater public involvement of the laity at all levels of the Church. Why can’t we have well qualified, nationally known and trusted lay experts named to the special task force announced by the president of the USCCB? We are too insular and closed in as a hierarchy, and so are some of our processes at the USCCB. The Second Vatican Council gave us not only the freedom but the obligation to utilize and engage the gifts and talents of the laity in the life and mission of the Church.

Beyond the McCarrick scandal, we have more work cut out for us with regard to putting into place protocols and institutional structures to build credibility in the hierarchy’s handling of sexual abuse cases going forward. History proves that we bishops are not capable of policing ourselves adequately on the issue of clergy sexual abuse. Why not include the laity to assist us with this problem? The document the Missouri Province of Bishops presented to the Committee for the Protection of Children and Young People on Oct. 6 was intended to offer a set of principles for the USCCB to consider as it was developing proposals for the full body of bishops, including the involvement of the laity. We Missouri bishops wanted something valuable to come from our November meeting.

And so, I was disappointed that even the mild proposals up for consideration at the Baltimore meeting had to be pulled from a vote. It was a rather harsh reminder to me of what many lay people have been saying throughout our Diocese: We bishops are ineffectual in our attempts to address the problem of abuse of power by the hierarchy. The Charter for the Protection of Children and Young People has had a marked impact on lowering the number of incidents of abuse by clergy since 2003. But with the aggravation of the McCarrick scandal, the laity and clergy are now rightfully asking that we get it all out, once and for all, and respond with an urgency that this crisis deserves. We literally have people dying because of the harm caused by predator clergy, and survivors of abuse are further victimized when we fail to take swift action. Seeing certain retired bishops who were notoriously responsible for covering up clergy sexual abuse at this year’s General Assembly in Baltimore as welcome guests was a slap in the face to all who have been wounded by the clergy. This example of episcopal arrogance and clericalism evidences the fact that we still don’t get the problem.

The whole Church is needed to solve our problem which the whole world knows about. What more do we have to hide? If we are going to move forward, we need to have authentic communion and a genuine synodal process. And this requires transparency and better communication between the clergy and the laity, between the USCCB and its own members, and between the USCCB and the Holy See. We need to become the Church Christ founded us to be.

Some of the most poignant comments I heard during the listening sessions in our Diocese were in response to the question asking for people’s dreams for their children and grandchildren. People spoke of a Church where their children and grandchildren would find the love, mercy and hope of Jesus Christ, a community filled by God’s graces and led by holy priests. Despite our current lethargy, I believe we are witnessing the rebirth and renewal of our Church in our day. And I feel very blessed to be part of that renewal with each of you. We are better together.

 

 

Bishop McKnight's column was first published at Making Connections, his column on the website of the Diocese of Jefferson City.

Jose, an Argentinian worker serving in Southeast Asia, tells of how he entered overseas service and what he has seen God do through his not-so-typical ministry.

DOVER — Delaware homeowners who face foreclosure, have fallen behind on their mortgage payments, or have questions about their mortgage can meet with lenders and housing counselors at two upcoming workshops in Dover on May 15 and Wilmington on May 16. At each free workshop, homeowners can also get information from the Attorney General’s Office […]

DOVER — Delaware homeowners who face foreclosure, have fallen behind on their mortgage payments, or have questions about their mortgage can meet with lenders and housing counselors at two upcoming workshops in Dover on November 13 and Wilmington on November 14. At each free workshop, homeowners can also get information from the Attorney General’s Office […]

The below workshops are being held to provide information regarding the Delaware State Employees’ Pension Plan benefits. There is no cost or pre-registration required to attend these workshops. Participants will learn how to prepare their own estimated benefit using the Pension Office website. You are encouraged to bring your Comprehensive Annual Statement. Please be on […]

A visit to any neighbourhood kirana shop will reveal piles of snacks, bakery goods, groceries, soaps and sanitisers that have been made in the immediate vicinity.

The concern is genuine as new hotspots are emerging in districts like Idukki and Kottayam that were earlier in the green zone and considered safe.

The Madras high court has ordered the Tamil Nadu government to close all liquor shops in the state, saying the social distancing protocol implemented to stem coronavirus growth are being violated. It...

DOVER, Del.– DNREC’s Division of Air Quality and industry partners will host Air Permitting Basics training workshops at 8 a.m., Wednesday, March 18, at DNREC’s Lukens Drive office, 391 Lukens Drive, New Castle, DE 19720, and again at 8 a.m., Thursday, March 26, in the DNREC Auditorium, 89 Kings Highway, Dover, DE 19901. Topics to be covered include an overview of DNREC’s Division of Air Quality and air permitting basics – with examples presented at the workshops for generators and boilers. Certificates for professional development hours will be available for those attending. Seating is limited and pre-registration is required. To register, and for more information, please visit https://dnrec.alpha.delaware.gov/air/permitting-basics/.

The Tamil Nadu government has decided to hike prices of liquor by up to Rs 20, as it is readying itself to open liquor outlets on Thursday.

‘Special corona fee’ levied to deter gatherings after police called in to break up crowds

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Officials in India’s capital have imposed a special tax of 70% on retail alcohol purchases to deter large gatherings at stores as authorities ease a six-week lockdown imposed to slow the spread of coronavirus.

Taxes on alcohol are a key contributor to the revenue of many of India’s 36 states and federal territories, most of which are running short of funds because of the lengthy disruption in economic activity caused by the virus.

WordPress ChopSlider plugin version 3 suffers from a remote SQL injection vulnerability.

The Belgian National Security Council, where all governments are represented, has decided to reopen all shops from 11 May onward, prime minister Sophie Wilmès announced at a press conference, adding "only one customer for every 10 square metres is allowed, and this for maximum half an hour". Bars, restaurants, markets and museums will remain closed. People are also allowed to see four extra people, instead of the current one person.

POLICE used batons to beat back thirsty Indians jostling to buy alcohol for the first time in 40 days as the government eased further the world’s biggest novel coronavirus lockdown. The government credits

Delish -- posted by Robbie 22

Greece's organization for medium and small businesses says the country risks product shortages as early as May, as businesses face liquidity problems and foreign suppliers will only accept cash for imports. Ciara Lee reports.

ABSTRACT

Interspecific hybridization can drive evolutionary adaptation to novel environments. The Saccharomycotina clade of budding yeasts includes many hybrid lineages, and hybridization has been proposed as a source for new pathogenic species. Candida orthopsilosis is an emerging opportunistic pathogen for which most clinical isolates are hybrids, each derived from one of at least four independent crosses between the same two parental lineages. To gain insight into the transcriptomic aftermath of hybridization in these pathogens, we analyzed allele-specific gene expression in two independently formed hybrid strains and in a homozygous strain representative of one parental lineage. Our results show that the effect of hybridization on overall gene expression is rather limited, affecting ~4% of the genes studied. However, we identified a larger effect in terms of imbalanced allelic expression, affecting ~9.5% of the heterozygous genes in the hybrids. This effect was larger in the hybrid with more extensive loss of heterozygosity, which may indicate a tendency to avoid loss of heterozygosity in these genes. Consistently, the number of shared genes with allele-specific expression in the two independently formed hybrids was higher than random expectation, suggesting selective retention. Some of the imbalanced genes have functions related to pathogenicity, including zinc transport and superoxide dismutase activities. While it remains unclear whether the observed imbalanced genes play a role in virulence, our results suggest that differences in allele-specific expression may add an additional layer of phenotypic plasticity to traits related to virulence in C. orthopsilosis hybrids.

IMPORTANCE How new pathogens emerge is an important question that remains largely unanswered. Some emerging yeast pathogens are hybrids originated through the crossing of two different species, but how hybridization contributes to higher virulence is unclear. Here, we show that hybrids selectively retain gene regulation plasticity inherited from the two parents and that this plasticity affects genes involved in virulence.

Big Tech is coming for your transaction data.

The Government was today warned that up to a third of independent shops will be unable to reopen when the lockdown lifts after facing "horrible" delays in accessing emergency government loans.

You can donate at virginmoneygiving.com/fund/FoodforLondonNOW

A kangaroo was spotted hopping through the empty streets of Adelaide amid the coronavirus lockdown.

The Scottish Government has recommended wearing face masks in enclosed public spaces like shops and public transport to stop the spread of coronavirus.

The Little Mix star raided her closet ahead of... a trip to the shops

A social media campaign quickly gathers followers as it shines a light on drought-affected towns struggling to maintain their businesses, and encourages people to buy remotely in the lead-up to Christmas.

In mid-March, WW International, also known as Weight Watchers, decided to close its 3,000 physical locations but didn’t want to leave members to fend for themselves in these trying times.