NEW CASTLE – The Delaware Department of Health and Social Services’ Division of Substance Abuse and Mental Health (DSAMH) announces significant advancement in capabilities for the Delaware Treatment and Referral Network (DTRN) with the launch of DTRN360, a Behavioral Health Coordination platform. DTRN360 is designed to bridge the gaps experienced by providers in caring for […]

WILMINGTON, Del. – Governor John Carney on Tuesday issued a State of Emergency to coordinate response and recovery efforts following the high winds, heavy rainfall, tornadoes, and flooding due to Tropical Storm Isaias. The State of Emergency is effective as of 3:00 p.m. on Tuesday, August 4, 2020, until further notice. “Several communities in Delaware experienced significant […]

The Delaware Heritage Commission and the Delaware Public Archives are pleased to announce the hiring of Ms. Margaret Hughes for the position of The State of Delaware's 250th Anniversary Coordinator.

The post The State of Delaware hires 250th Anniversary Coordinator appeared first on Delaware Public Archives - State of Delaware.

Photo Caption: From left to right: Anna McDermott of the Food Bank of Delaware, State Rep. Ed Osienski, Lt. Governor Bethany Hall-Long, Cathy Kanefsky, Food Bank of Delaware President and CEO, and Megan Zavala of the Food Bank of Delaware pose for a photo in front of the Hurricane Helene donation to impacted areas.  NEWARK, […]

WILMINGTON, Del. – Governor John Carney on Friday issued a statewide drought watch after receiving guidance from the Delaware Water Supply Coordinating Council (WSCC). Delawareans are asked to voluntarily reduce outdoor uses of water during the drought watch. This decision follows an assessment of conditions by the WSCC on October 25. The drought watch will remain in effect until […]

Hello Community,

Is there any simple way how i can get the coordinates of all the shapes in a layout view?

Currently i'm flattening the layout, getting all the lpps from CV and using setof to get all the shapes of a layer and looping through them to get the coordinates.

Is there a way to do it without having to flatten the layout view and shapes merged or any other elegant way to do it if we flatten it?

Also, dbWriteSkill doesn't give output how i desired

Thanks,

Shankar

Manchester United legend, Rio Ferdinand has suggested that new manager, Ruben Amorim may have made a mistake in not keeping former interim manager, Ruud van Nistelrooy at the club. Amorim arrived at Man United on Monday to officially take charge at Old Trafford having been named Erik ten Hag’s permanent replacement a few weeks ago. […]

Man Utd: Rio Ferdinand identifies first mistake Amorim has made

[UNHCR] UNHCR, the UN Refugee Agency has just concluded a three-day event, hosting partners and Governments from the East and Horn of Africa, Great Lakes Region and Yemen, to review strategies for comprehensive solutions to the ongoing displacement crisis in Somalia. The meeting brought together representatives from Uganda, Yemen, Djibouti, Ethiopia and Kenya, as well as the regional body, Intergovernmental Authority on Development (IGAD) and provided a platform for sharing insights and aligning efforts among

  Matthias Schmale is the Assistant Secretary-General, UN Resident and Humanitarian Coordinator in Ukraine. Schmale brings more than 30 years of experience in humanitarian and development work. He previously served as Senior Adviser to the UN Development Coordination Office’s regional team for Africa, as Resident and Humanitarian Coordinator (a.i) in Nigeria, and in several high-level […]

The same genetic tools being used to resurrect the woolly mammoth and dodo could help many other vulnerable species that have yet to die out

In 2022, physicists were excited by hints that something was wrong with our understanding of the universe - but new results have put that in doubt

Why childhood is so protracted has long been mysterious, now a spate of archaeological discoveries suggest an intriguing explanation

Background

Quality of life is impaired in patients with sarcoidosis. The King's Sarcoidosis Questionnaire (KSQ) is a brief questionnaire assessing health-related quality of life in patients with sarcoidosis, comprising subdomains of General Health Status (GHS), Lung, Medication, Skin and Eyes. The aim of this study was to enhance the validation of the KSQ, incorporating longitudinal validation and known-groups validity in a cohort with mild sarcoidosis.

Dihydropyrimidinase (DHP) deficiency is an autosomal recessive metabolic disorder caused by biallelic pathogenic variants of DPYS. Patients with DHP deficiency exhibit a broad spectrum of phenotypes, ranging from severe neurological and gastrointestinal involvement to cases with no apparent symptoms. The biochemical diagnosis of DHP deficiency is based on the detection of a significant amount of dihydropyrimidines in urine, plasma, and cerebrospinal fluid samples. Molecular genetic testing, specifically the identification of biallelic pathogenic variants in DPYS, has proven instrumental in confirming the diagnosis and facilitating family studies. This case study documents the diagnostic journey of an 18-yr-old patient with DHP deficiency, highlighting features at the severe end of the clinical spectrum. Notably, our patient exhibited previously unreported skeletal features that positively responded to bisphosphonate treatment, contributing valuable insights to the clinical characterization of DHP deficiency. Additionally, a novel DPYS variant was identified and confirmed pathogenicity through metabolic testing, further expanding the variant spectrum of the gene. Our case emphasizes the importance of a comprehensive diagnostic approach using genetic sequencing and metabolic testing for accurate diagnosis.

BackgroundDuring the COVID-19 pandemic, global trends of reduced healthcare-seeking behaviour were observed. This raises concerns about the consequences of healthcare avoidance for population health.AimTo determine the association between healthcare avoidance during the early stages of the COVID-19 pandemic and all-cause mortality.Design and settingThis was a 32-month follow-up within the population-based Rotterdam Study, after sending a COVID-19 questionnaire at the onset of the pandemic in April 2020 to all communty dwelling participants (n = 6241/8732, response rate 71.5%).MethodCox proportional hazards models assessed the risk of all-cause mortality among respondents who avoided health care because of the COVID-19 pandemic. Mortality status was collected through municipality registries and medical records.ResultsOf 5656 respondents, one-fifth avoided health care because of the COVID-19 pandemic (n = 1143). Compared with non-avoiders, those who avoided health care more often reported symptoms of depression (n = 357, 31.2% versus n = 554, 12.3%) and anxiety (n = 340, 29.7% versus n = 549, 12.2%), and more often rated their health as poor to fair (n = 336, 29.4% versus n = 457, 10.1%) . Those who avoided health care had an increased adjusted risk of all-cause mortality (hazard ratio [HR] 1.30, 95% confidence interval [CI] = 1.01 to 1.67), which remained nearly identical after adjustment for history of any non-communicable disease (HR 1.20, 95% CI = 0.93 to 1.54). However, this association attenuated after additional adjustment for mental and physical self-perceived health factors (HR 0.93, 95% CI = 0.71 to 1.20).ConclusionThis study found an increased risk of all-cause mortality among individuals who avoided health care during COVID-19. These individuals were characterised by poor mental and physical self-perceived health. Therefore, interventions should be targeted to these vulnerable individuals to safeguard their access to primary and specialist care to limit health disparities, inside and beyond healthcare crises.

The five-film Kannada anthology is a realistic exploration of people on the margins of the film industry

NORTH Melbourne coach Brad Scott’s embarrassing umpire’s scandal just got a whole lot worse for his football club and his own wallet.

The 3.2-million-year-old human ancestor known as Lucy rose to fame through an incredible combination of circumstances

When traveling, the hotel becomes Sword & Plough�s mobile office, and Holiday Inn� hotels have become an integral extension of their team while on the road.

Is a Nonsurgical Facelift a Reality and How Does it Impact Facial Aging?

Cardinal Health, which provides medical products and services to many of America�s most prestigious medical institutions, introduces the Hospital Quality at Home� brand.

Clinton is helping

Highlights: Eggs are a nutrition-packed superfood, containing essential amino acids, vitamins, and minerals

The newly developed NCCCS electronic app aims to enhance the care coordination skills of medlinknurses/medlink responsible for managing critically ill patients on life support.

Berlin ; Boston : De Gruyter, [2023]

Durham : Duke University Press, [2023]

Ciudad de México : Bonilla Artigas Editores ; Universidad Autónoma del Estado de Morelos, 2020.

Mexico, D.F. : Bonilla Artigas editores, S.A. de C.V., 2015.