Republican state Sen. Victoria Spartz had the biggest personal loan, giving her campaign $750,000 while raising under $10,000.

IndyStar reached out to every candidate to ask questions about topics Hoosiers care about. Here's what the Republicans on the ballot said.

Beth Henderson on the "Good Morning Grant County" radio show said U.S. Rep. Susan Brooks encouraged her to run for Indiana's 5th District.

Republican state Sen. Victoria Spartz had the biggest personal loan, giving her campaign $750,000 while raising under $10,000.

A lawyer who served as legal counsel for Mother Teresa told Republican Chuck Dietzen to stop using Mother Teresa's name and image in ads.

Indiana democratic gubernatorial candidate Woody Myers named Linda Lawson as his running mate in an announcement Friday morning.

According to report from Front Office Sports, former Colts punter Pat McAfee may be a candidate to join the "Monday Night Football" broadcast.

Indiana democratic gubernatorial candidate Woody Myers named Linda Lawson as his running mate in an announcement Friday morning.

It was supposed to be the first day of a new mayoral term but the coronavirus crisis has delayed the election to 2021.

“People who have the most exaggerated features tend to make the worst caricature subjects, and in that sense, I hate drawing Bernie,” says one.

TidalWave Productions is releasing Buttigieg and Bloomberg comic books to sit alongside its Warren biography.

“The transition happens so quickly; it’s like you don’t even get to move your furniture out until the new president takes the oath of office,” Obama told Gayle King in an interview at Essence Festival.

The presidential election is closer than you think, but thus far the celebrities are staying pretty far away.

You know about Beto O'Rourke on the guitar, of course, but what about Bernie Sanders's spoken-word album?

Objective: To develop a novel approach to generate individual maps of white matter (WM) innate immune cell activation using ¹⁸F-DPA-714 translocator protein (TSPO) positron emission tomography (PET), and to explore the relationship between these maps and individual trajectories of disability worsening in patients with multiple sclerosis (MS). Methods: Patients with MS (n = 37), whose trajectories of disability worsening over the 2 years preceding study entry were calculated, and healthy controls (n = 19) underwent magnetic resonance magnetic and ¹⁸F-DPA-714 PET. A threshold of significant activation of ¹⁸F-DPA-714 binding was calculated with a voxel-wise randomized permutation-based comparison between patients and controls, and used to classify each WM voxel in patients as characterized by a significant activation of innate immune cells (DPA+) or not. Individual maps of innate immune cell activation in the WM were employed to calculate the extent of activation in WM regions-of-interests and to classify each WM lesion as "DPA-active", "DPA-inactive" or "unclassified". Results: Compared with the WM of healthy controls, patients with MS had a significantly higher percentage of DPA+ voxels in the normal-appearing WM, (NAWM in patients=24.9±9.7%; WM in controls=14.0±7.8%, p<0.001). In patients with MS, the percentage of DPA+ voxels showed a significant increase from NAWM, to perilesional areas, T2 hyperintense lesions and T1 hypointense lesions (38.1±13.5%, 45.0±17.9%, and 51.9±22.9%, respectively, p<0.001). Among the 1379 T2 lesions identified, 512 were defined as DPA-active and 258 as DPA-inactive. A higher number of lesions classified as DPA-active (OR=1.13, P = 0.009), a higher percentage of DPA+ voxels in the NAWM (OR=1.16, P = 0.009) and in T1-spin-echo lesions (OR=1.06, P = 0.036), were significantly associated with a retrospective more severe clinical trajectory in patients with MS. Conclusion: A more severe trajectory of disability worsening in MS is associated with an innate immune cells activation inside and around WM lesions. ¹⁸F-DPA-714 PET may provide a promising biomarker to identify patients at risk of severe clinical trajectory.

The increasing prevalence of type 2 diabetes poses a major challenge to societies worldwide. Blood-based factors like serum proteins are in contact with every organ in the body to mediate global homeostasis and may thus directly regulate complex processes such as aging and the development of common chronic diseases. We applied a data-driven proteomics approach, measuring serum levels of 4,137 proteins in 5,438 elderly Icelanders and identified 536 proteins associated with prevalent and/or incident type 2 diabetes. We validated a subset of the observed associations in an independent case-control study of type 2 diabetes. These protein associations provide novel biological insights into the molecular mechanisms that are dysregulated prior to and following the onset of type 2 diabetes and can be detected in serum. A bi-directional two-sample Mendelian randomization analysis indicated that serum changes of at least 23 proteins are downstream of the disease or its genetic liability, while 15 proteins were supported as having a causal role in type 2 diabetes.

A year ago, Danny Farquhar was not going to be in the middle of a spring storyline. That's going to change this spring as he tries to win a spot in the Yankees' bullpen

John McCain once called televangelists Pat Robertson and Jerry Falwell "agents of intolerance," but now the Republican senator from Arizona is currying favor with social conservatives. Sen. Hillary Rodham Clinton (D-N.Y.) now opposes the Iraq war, although she used to support it. Sen. Barack Obama...

On the eve of crucial presidential primaries in Indiana and North Carolina, Sen. Barack Obama (D-Ill.) has found himself dogged by questions about his former pastor, the Rev. Jeremiah A. Wright Jr. As the Democratic front-runner's popularity has suffered after public statements by Wright about ra...

Any discussion in politics of the future of education in Ohio inevitably turns to the Electronic Classroom of Tomorrow.

Stuttgart : F. Enke, 1883.

Affinity groups known as caucuses let teacher-candidates at the University of Washington gather with others who share part of their identity, such as race, ethnicity, gender, or sexual orientation.

There are five key values to consider when separating campaign rhetoric from how a candidate would actually govern, writes Robert Feirsen.

Candidate genes involved in thrombophilia, inflammation, and preterm birth have previously been associated with cerebral palsy. Most studies to date have included small cohorts, did not allow for multiple testing, and require replication.

This study of children with cerebral palsy and their mothers did not confirm previously reported candidate gene associations. Prothrombin gene mutation was associated with hemiplegia in children born at term to mothers with a reported infection during pregnancy. (Read the full article)

Central apnea sometimes complicates bronchiolitis. Because apnea tends to occur early in the course of bronchiolitis, there is a danger that infants may be discharged from the emergency department only to subsequently develop apnea at home.

This study prospectively derived clinical decision rules to help emergency physicians admit infants at risk for apnea while discharging those not at risk. (Read the full article)

Drug repositioning is the only feasible option to address the COVID-19 global challenge immediately. We screened a panel of 48 FDA-approved drugs against SARS-CoV-2 which were pre-selected by an assay of SARS-CoV and identified 24 potential antiviral drug candidates against SARS-CoV-2 infection. Some drug candidates showed very low micromolar IC50s and in particular, two FDA-approved drugs - niclosamide and ciclesonide – were notable in some respects.

JooYoung Seo, a doctoral candidate in the College of Education’s Learning, Design, and Technology program, has secured a highly competitive internship with RStudio that will allow him to help people just like himself — those with severe visual impairments.

One out of three reputed firms is having a non-Dane at the steerage as organizations in Denmark are viewing the whole globe as their pool for notable talents. The point when Denmark's biggest organizations require a CEO, they are progressively set outside…

Denmark is taking a gander at sourcing talented candidates from India. The nation has set up a 'Work in Denmark' special center right at Danish Embassy in India in order to expedite work provisions as well as applications from the professionals of…

Quebec held two draws in October and issued 162 invitations to apply to the aspirants in the Quebec Skilled Worker Program. A Gradual ProgressFirstly, On October 23, it invited 89 persons to meet the labor market requirements. Also, the Candidates…

On November 26th British Columbia held a draw and has extended 348 invitations to Skilled Workers as well as International Graduates in its new Provincial Nominee Program. The draw covered five provincial streams. These Skilled workers of the provincial…

The immigration authorities in Ontario held their largest draw on December 11th4wsqor 2019, and issued 667 Notifications of Interest to such candidates who had a profile in Express Entry Pool. This was the first draw in the Skilled Trades stream after…

Nova Scotia held a draw in the Labor Market Priorities stream on December 20 and invited 144 candidates belonging to the Express Entry having the required work experience related to public relations, advertising, or marketing sectors. The category of…

Saskatchewan has invited 595 candidates belonging to Express Entry and Occupations In-Demand categories to seek the provincial nomination for permanent residence in Canada.Making a Fine ProgressOn December 20 a draw was held for The Saskatchewan Immigrant…

On January 9th, Ontario conducted a draw for the first time after May 2019 in the French-Speaking Skilled Worker stream that is linked to Express Entry. The draw in Ontario Immigrant Nominee Program issued 242 Notifications of Interest.The qualifying…

The immigration officials of Saskatchewan issued 308 invitations that target 82 NOC codes in the first skilled worker draw for Expression of Interest draw in the present year on January 9th. This draw was held in Saskatchewan Immigrant Nominee Program…

British Columbia invited 70 candidates in the initial BC PNP Tech Pilot draw for the present year on January 14th.  It issued invitations through four streams of the British Columbia Provincial Nominee Program as mentioned below:SI – Skilled Workers…

Prince Edward Island held the first draw for the year on January 16th and has issued 123 invitations to immigration candidates.Forward looking ProgramThe PEI Provincial Nominee Program invited the candidates in the Labor Impact, and Business Impact class…

Canadian Immigration authorities are beginning the issuing process at a great pace. In an Express Entry draw conducted on January 22, 2020, they issued 3,400 Invitations to Apply. The CRS score had a decline of two points in comparison to the draw held…

150 invitations were issued to Express Entry candidates to apply and seek the Alberta provincial nomination on January 9. The Candidates having a 350 CRS score received these NOIs.Through the Alberta Express Entry Stream the Alberta Immigrant Nominee…

British Columbia conducted an Entrepreneur Immigration draw and issued 25 invitations to candidates belonging to two streams on January 14th.This draw of British Columbia Provincial Nominee Program had 18 invitations in General Entrepreneur stream as…

Kapil Mishra is a former Aam Aadmi Party (AAP) leader-turned BJP candidate for the Delhi election. When he was with the AAP, Mr Mishra was elected from Delhi's Karawalnagar seat in the 2014 Delhi...

Arvinder Singh Lovely is a Congress leader who had walked out of his party in 2017 to join the BJP. He returned to the Congress in February 2018. Mr Lovely, who has been the Delhi Education Minister...

Satyendar Jain is an Aam Aadmi Party (AAP) leader and a minister in Arvind Kejriwal's cabinet. He holds multiple portfolios including the Health Ministry.

Dharampal Lakra of the Aam Aadmi Party (AAP) is the richest candidate in Delhi. He has declared wealth of close to Rs 300 crore.

Krishna Tirath, a union minister in the United Progressive Alliance (UPA) government, is the Congress's candidate from Patel Nagar. The leader had rejoined the Congress last year after being a BJP...

Aam Aadmi Party (AAP) leader Raghav Chadha, party's candidate from central Delhi's Rajinder Nagar, is pitted against BJP veteran RP Singh, a 58-year-old advertising professional from the same...