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En este episodio de El Alargue hablamos con Sergio Luis Henao sobre la llegada de Supermán López al Team Medellín y el rumor de un eventual fichaje a la escuadra paisa.

En este episodio de El Alargue analizamos a los equipos que mejor juegan al fútbol en Colombia y dialogamos con Juan Fernando Caicedo, goleador del Deportes Tolima.

Álvaro Montero, portero de Millonarios, habló de su actualidad en el cuadro bogotano, luego de haber sido la figura del equipo en la victoria 1-0 sobre el Boyacá Chicó. El guardameta guajiro aprovechó los micrófonos de El Alargue de Caracol Radio para expresar su satisfacción y deseo de poder continuar en el club por más años.

El experimentado zaguero central viene de poner fin a su etapa con el Independiente Medellín.

El centrocampista habló de los objetivos del equipo, que puede hacer historia si termina invicto la fase del todos contra todos.

En Caracol Radio estuvo el general José Gualdrón, comandante Policía de Bogotá, compartiendo detalles sobre lo último del caso.

En 6AM Hoy por Hoy, Jaime Lombana, el abogado de Álvaro Uribe, destaca la importancia de una defensa rigurosa para garantizar un proceso justo ante la situación júridica del expresidente.

En 6AM Hoy por Hoy, el Dr. Carlos Álvarez, médico infectólogo y epidemiólogo, aborda las preocupaciones sobre la vacuna covid-19 AstraZeneca y sus posibles efectos secundarios.

Además de ser acusada de ir en contra de los derechos humanos y de representar un algo riesgo por poder ser captada por el Clan de Golfo, el senador Ariel Ávila denunció que la propuesta de la vigilancia privada en Sincelejo podría ser resultado de un davor político del alcalde de la ciudad.

En el programa 6AM de Caracol Radio, hablo el nuevo presidente de la Comisión Primera de en que se basara su trabajo, y de lo que piensa sobre el "fast track"

En 6AM Hoy por Hoy de caracol Radio estuvo el entrenador de Ángel Barajas, gimnasta colombiano que ganó medalla de plata en la disciplina de barra fija. Le contamos lo que dijo.

En el programa AM de Caracol Radio, Habló la familia del ganador de plata en los Juegos Olímpicos de París y destacaron el trabajo de Ángel Barajas a lo largo de los años

En el programa 6AM Hoy por Hoy de Caracol Radio, habló la familia del ganador de plata en los Juegos Olímpicos en París y destacaron el trabajo de Ángel Barajas a lo largo de los años  

En el programa 6AM Hoy por Hoy de Caracol Radio habló el familiar del ganador de la plata en los Juegos Olímpicos y destacaron el trabajo de Ángel Barajas a lo largo de los años

En el programa 6AM de Hoy por Hoy de Caracol Radio, el senador Ariel Ávila habló sobre las negociaciones que tiene la administración de turno con este grupo armado. 

En 6AM de Caracol Radio estuvo el senador Ariel Ávila, para hablar sobre qué viene para Colombia tras el cierre del proceso de paz con el ELN.

Néstor Álvarez, presidente de la Asociación de Pacientes de Alto Costo, habló sobre cuál ha sido la respuesta del Gobierno y ministros ante el desabastecimiento de medicamentos 

El senador Ariel Ávila, estuvo en 6AM, para abordar cómo será la transición y en qué consisten los 7 acuerdos que destaparon el camino para la reforma al Sistema General de Participaciones.

Ariel Ávila, senador, habló sobre en qué ámbitos podría la gobernabilidad de Donald Trump afectaría a Colombia

One person was killed and another was injured in a crash on Colorado 93 in Jefferson County near Arvada on Wednesday afternoon.

[Written by Don Burgess] Did you know that one of Bermuda’s first great Olympic hopes is a former world record holder in the International Swimming Hall of Fame? And how he came to represent Bermuda is controversial, and that process will never happen again. Hubert Leonard Spence represented Bermuda at the 1936 Olympic Games in […]

В поколении людей, родившихся в 1930-е годы, были невероятно талантливые ученые, среди которых можно назвать Серафиму Евгеньевну Никитину. С. Е. обладала множеством способностей. Она могла бы стать певицей или актрисой, музыковедом, этнографом, географом, биологом, физиком или химиком (химиками были ее родители, а старший брат — физиком). Но стала филологом, и филологом необыкновенным, многопрофильным.

Сообщение Серафима Евгеньевна Никитина (01.09.1938–02.10.2024) появились сначала на Троицкий вариант — Наука.

In this episode we chat about the final of Euro 2024 which saw Spain beat England 2-1. We discuss how this was a game too far for Gareth Southgate's side, pay credit to the Spanish team which has been the best at this tournament, as well as discussing the potential impact another painful defeat might have on the likes of Bukayo Saka and Declan Rice, who have been playing non-stop for 11 months now. There's a transfer round-up, in as much as that's possible with so little transfer news, plus listener questions about online tribalism, the number 10 shirt, who might be in the squad for the US tour, Alvaro Morata, and lots more.

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With the new season ahead I'm joined by four guests to look forward to the 2024-25 campaign. I chat separately to Amy Lawrence, Nick Wright (Sky Sports), Adrian Clarke and Dara O Briain about the things they're excited for, what they'd like to see happen in the transfer market, the players they're keen to see pull on the red and white, proactive goalkeeping, some of the young players who impressed on the US tour, Riccardo Calafiori, Snoop Dogg (sort of), and lots more.

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In this episode of the Arsenal Women Arsecast Tim and Jamie pore over the 2-1 defeat to Chelsea on Saturday and try to dissect how to separate this result and performance from the wider funk that Arsenal seem to be in. Did Arsenal just 'get varianced'? And is it possible to separate that from the wider malaise? Tim and Jamie talk about the defending on the goals conceded and whether a lack of confidence in attack had an impact on the result with more than one proven player low on confidence. In the second half, Tim and Jamie deal with listener questions on Rosa Kafaji and the lack of integration for young players, on Clare Wheatley's role and whether more communication from 'upstairs' is needed at the club and on the delicate balance between rotation and trying and failing to find partnerships that work.

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Google has warned that a security flaw impacting its Android operating system has come under active exploitation in the wild. The vulnerability, tracked as CVE-2024-43093, has been described as a privilege escalation flaw in the Android Framework component that could result in unauthorized access to "Android/data," "Android/obb," and "Android/sandbox" directories, and their respective

Jacques R. Fresco, the emeritus Damon B. Pfeiffer Professor in the Life Sciences and an emeritus professor of molecular biology, died on Dec. 5. He served on Princeton's faculty for 53 years before retiring in July 2013.

In 1993, terrorists detonated a car-bomb in an underground garage of the World Trade Center complex in New York City, killing six, injuring more than a thousand, and causing more than $300 million in damage. In all, ten militant Islamist conspirators were convicted of involvement in the bombing, including Yousef, who also bombed an important Shia shrine in Iran in 1994 and later planned a large-scale terrorist scheme that included killing the pope. What alleged 9-11 mastermind is Yousef's uncle?

Sự cải thiện lớn nhất của Việt Nam vào năm 2024 là ảnh hưởng ngoại giao và ảnh hưởng văn hóa, song thước đo về mạng lưới quốc phòng sụt giảm.

The Central American nation of El Salvador currently holds nearly 5,932 Bitcoin (BTC), and sits on over $93 million of… Continue reading El Salvador’s Bitcoin adoption is paying off: $93M unrealized profit

The post El Salvador’s Bitcoin adoption is paying off: $93M unrealized profit appeared first on ReadWrite.

Mammalian circadian clocks are driven by transcription/translation feedback loops composed of positive transcriptional activators (BMAL1 and CLOCK) and negative repressors (CRYPTOCHROMEs (CRYs) and PERIODs (PERs)). CRYs, in complex with PERs, bind to the BMAL1/CLOCK complex and repress E-box–driven transcription of clock-associated genes. There are two individual CRYs, with CRY1 exhibiting higher affinity to the BMAL1/CLOCK complex than CRY2. It is known that this differential binding is regulated by a dynamic serine-rich loop adjacent to the secondary pocket of both CRYs, but the underlying features controlling loop dynamics are not known. Here we report that allosteric regulation of the serine-rich loop is mediated by Arg-293 of CRY1, identified as a rare CRY1 SNP in the Ensembl and 1000 Genomes databases. The p.Arg293His CRY1 variant caused a shortened circadian period in a Cry1−/−Cry2−/− double knockout mouse embryonic fibroblast cell line. Moreover, the variant displayed reduced repressor activity on BMAL1/CLOCK driven transcription, which is explained by reduced affinity to BMAL1/CLOCK in the absence of PER2 compared with CRY1. Molecular dynamics simulations revealed that the p.Arg293His CRY1 variant altered a communication pathway between Arg-293 and the serine loop by reducing its dynamicity. Collectively, this study provides direct evidence that allosterism in CRY1 is critical for the regulation of circadian rhythm.