With Mother's Day only a few days away, businesses are coming up with creative ways to help your family celebrate. Everything from brunch in a box to colourful bouquets and home delivered chocolate.

Florian Schneider (date: 5/9/2020 - Rank: 10)

What this country needs is another group with a very long name.

See the Full Flower Moon, last supermoon of 2020, bloom in these stunning photos  Space.comIn Pictures: 'Full-flower supermoon' amid coronavirus lockdowns  Aljazeera.comIn pics | Last supermoon in 2020: Stunning views from around th...

Florist Sam Solis said in 21 years of business, he’s never seen a busier Mother’s Day. He and other florists and bakers are working double time to help fete the mothers of British Columbia.

Ten properties, including homes and businesses, have already been evacuated as the community braces against rising water levels.

Most of the animals at the B.C. Wildlife Park in Kamloops are unfazed by the absence of paying visitors since it closed in March over COVID-19 concerns. But Blue the turkey appears "bummed," staff say.

SOLIDWORKS 2020 continues our mission of delivering powerful Simulation Capabilities with enhancements that provide increased power, more realistic simulations, and more efficient workflows. When running simulation on Weldment Structures, beam elements are typically used since they are fast to setup

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Product complexity places unique challenges on Engineering Teams, making the interaction between Mechanical and Electrical designers more critical than ever. New enhancements in SOLIDWORKS 2020 have taken the ECAD/MCAD collaboration to the next level, by providing an intelligent collaborative environment

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Caitlin, an intern, reflects on the lives touched by God during the OM outreach to Sainte Marie Island off the coast of Madagascar.

Free flowers are an opportunity to share about God's power and love.

The care the head teacher of Chiyembekezo School shows to her pupils even outside the classroom has a ripple effect on the larger community.

OM Ships’ Logos Hope is back in the water after 90-day dry dock marathon but more work is needed to sail again.

An update about the flood damage in Eastern Australia

Compiled by Antigoni Markitani

I’ve been longing to eat Korean food ever since seeing Bong Joon-Ho’s phenomenal Oscar-winning film, Parasite, his interrogation of class and wealth on the plate. The wealthy mother tells her housekeeper to prepare jjapaguri, essentially an everyday dish, commonly made with two sorts of instant noodles. What makes this one exclusive and upper class is its topping of steak, from indigenous, highly prized Hanwoo cattle, which is way more expensive than Waygu beef would be here. Only the Korean

Police have issued more than 140 fixed-penalty notices to people flouting coronavirus lockdown rules in Scotland in the week since new powers came into force.

DRAKE - DARK LANE DEMO TAPES

The Florida Department of Education is in a bitter dispute with a software company it hired to create online resources aligned with the standards for teachers and students.

Industry observers attribute the rise to heightened interest in ed-tech initiatives, decreasing technology costs, and the move to Common Core standards.

Analysts and business officials wonder if the education technology market faces the risk of a crash, similar to what occurred during the dot-com bust in the 1990s.

Gov. Jeb Bush has warned that Florida won't meet class-size limits without taking such steps as expanding private school vouchers, lifting restrictions on the number of charter schools, and moving to year-round schedules.

As lawmakers weigh expansion of the state’s voucher and tax-credit scholarship programs, some renew a push for anti-discrimination protection for lesbian, gay, bisexual, transgender, and queer students.

Adults born at very low birth weight (VLBW) (<1.5 kg) have higher blood pressure and higher fasting insulin levels than their peers born at term. However, they show no signs of endothelial dysfunction in childhood and in adolescence.

Adults born at a VLBW showed no endothelial dysfunction compared with term adults. They had, however, a thicker intima-media layer in relation to lumen size. More rapid growth during their first weeks of life was associated with better endothelial function. (Read the full article)

The pathophysiology of pediatric sports-related concussion (SRC) is largely unknown. Studies of concussed adults have identified neuronal and axonal injury and time-limited metabolic disruptions. An experimental animal model has also demonstrated physiologic perturbations, including reduced cerebral blood flow (CBF).

Using MRI techniques, we found no evidence of neuronal, axonal, or metabolic disruptions in 12 children with SRC. However, when compared with controls, statistically significant alterations in CBF were defined and frequently persisted beyond 30 days after injury. (Read the full article)

Excess tissue oxygenation should be avoided during neonatal resuscitation, especially in premature infants. Delivered oxygen concentrations when using a self-inflating bag (SIB) at oxygen flows <1 L/min remain to be established.

Low oxygen concentrations (30%– 40%) can be delivered with a SIB at an oxygen flow <1 L/min. A practical scheme has been developed correlating the oxygen flow rate and the corresponding delivered fraction of oxygen when using a neonatal SIB. (Read the full article)

Heated, humidified high-flow nasal cannula (HHHFNC) is a noninvasive mode of respiratory support that is commonly used in the majority of US NICUs. No large randomized trial has evaluated safety or efficacy of HHHFNC.

This large randomized controlled trial suggests that HHHFNC is as effective as nCPAP for noninvasive respiratory support and can be safely applied to a wide range of neonates. (Read the full article)

Animal studies document dose-dependent and duration-of-therapy-dependent fluoroquinolone cartilage toxicity in weight-bearing joints. Preliminary pediatric data collected after fluoroquinolone treatment and up to 1 year posttreatment in blinded and unblinded studies suggest the possibility of cartilage toxicity in children.

These are the first prospectively collected data on fluoroquinolone musculoskeletal safety collected posttherapy from randomized, comparative studies of respiratory tract infections and analyzed at 5 years. Long-term musculoskeletal adverse events occurred with equal frequency in both levofloxacin and comparator groups. (Read the full article)

Trees, shrubs and woody vines are among the top food sources for honey bees in urban environments, according to an international team of researchers. By using honey bees housed in rooftop apiaries in Philadelphia, the researchers identified the plant species from which the honey bees collected most of their food, and tracked how these food resources changed from spring to fall. The findings may be useful to homeowners, beekeepers and urban land managers who wish to sustain honey bees and other bee and pollinator species.

Florfenicol belongs to a class of phenicol antimicrobials widely used as feed additives and for the treatment of respiratory infections. In recent years, increasing resistance to florfenicol has been reported in Campylobacter spp., the leading foodborne enteric pathogen causing diarrheal diseases worldwide. Here, we reported the identification of fexA, a novel mobile florfenicol resistance gene in Campylobacter. Of the 100 Campylobacter jejuni strains isolated from poultry in Zhejiang, China, nine of them were shown to be fexA positive, and their whole genome sequences were further determined by integration of Illumina short-read and MinION long-read sequencing. The fexA gene was found in the plasmid of one strain and chromosomes of eight strains, and its location was verified by S1 nuclease pulsed-field gel electrophoresis (S1-PFGE) and Southern blotting. Based on comparative analysis, the fexA gene was located within a region with the tet(L)-fexA-catA-tet(O) gene arrangement, demonstrated to be successfully transferrable among C. jejuni strains. Functional cloning indicated that acquisition of the single fexA gene significantly increased resistance to florfenicol, whereas its inactivation resulted in increased susceptibility to florfenicol in Campylobacter. Taken together, these results indicated that the emerging fexA resistance is horizontally transferable, which might greatly facilitate the adaptation of Campylobacter in food producing environments where florfenicols are frequently used.

Treatment of exacerbations of chronic Pseudomonas aeruginosa infections in patients with cystic fibrosis (CF) is highly challenging due to hypermutability, biofilm formation and an increased risk of resistance emergence. We evaluated the impact of ciprofloxacin and meropenem as monotherapy and in combination in the dynamic in vitro CDC biofilm reactor (CBR). Two hypermutable P. aeruginosa strains, PAOmutS (MIC_{ciprofloxacin} 0.25 mg/L, MIC_meropenem 2 mg/L) and CW44 (MIC_{ciprofloxacin} 0.5 mg/L, MIC_meropenem 4 mg/L), were investigated for 120h. Concentration-time profiles achievable in epithelial lining fluid (ELF) following FDA-approved doses were simulated in the CBR. Treatments were ciprofloxacin 0.4g every 8h as 1h-infusions (80% ELF penetration), meropenem 6 g/day as continuous infusion (CI; 30% and 60% ELF penetration) and their combinations. Counts of total and less-susceptible planktonic and biofilm bacteria and MICs were determined. Antibiotic concentrations were quantified by UHPLC-PDA. For both strains, all monotherapies failed with substantial regrowth and resistance of planktonic (≥8log₁₀ CFU/mL) and biofilm (>8log₁₀ CFU/cm²) bacteria at 120h (MIC_{ciprofloxacin} up to 8 mg/L, MIC_meropenem up to 64 mg/L). Both combination treatments demonstrated synergistic bacterial killing of planktonic and biofilm bacteria of both strains from ~48h onwards and suppressed regrowth to ≤4log₁₀ CFU/mL and ≤6log₁₀ CFU/cm² at 120h. Overall, both combination treatments suppressed amplification of resistance of planktonic bacteria for both strains, and biofilm bacteria for CW44. The combination with meropenem at 60% ELF penetration also suppressed amplification of resistance of biofilm bacteria for PAOmutS. Thus, combination treatment demonstrated synergistic bacterial killing and resistance suppression against difficult-to-treat hypermutable P. aeruginosa strains.

Already home to a thriving ecosystem of private school choice, the state’s lawmakers want vouchers for thousands of new students.

In India and China, indigenous drug manufacturers market arbitrarily combined parenteral β-lactam and β-lactamase inhibitors (BL-BLIs). In these fixed-dose combinations, sulbactam or tazobactam is indiscriminately combined with parenteral cephalosporins, with BLI doses kept in ratios similar to those for the approved BL-BLIs. Such combinations have been introduced into clinical practice without mandatory drug development studies involving pharmacokinetic/pharmacodynamic, safety, and efficacy assessments being undertaken. Such unorthodox combinations compromise clinical outcomes and also potentially contribute to resistance development.

A tweet from the former president about education's role in addressing inequality and lack of opportunities drew split reactions and a chance to review his record and where K-12 stands in the political sphere.

Severe flooding is affecting families and communities across Bangladesh's districts. Families who are already poor have lost everything and are in desperate need of emergency assistance and hope.

Microsoft realizes you can use the sea as a giant heatsink and save a small fortune in cooling costs.

The Delaware State Housing Authority (DSHA), in partnership with five local housing counseling agencies, is hosting “Keeping Your Home Afloat”, a Statewide Foreclosure Prevention Open House, on Monday, July 22nd from 5:00pm to 7:30pm. Attendees will learn how the Making Home Affordable Program may be able to help them reduce the amount they owe on their mortgage. Homeowners who are “underwater”, or owe more than their homes are worth, are especially encouraged to come get more information about the MHA Program’s Principal Reduction Alternative.

The Flo by Moen is a smart water meter that monitors water usage throughout your home, tests your system for leaks, and protects against water damage with an automatic shutoff feature.

The Flo by Moen Smart Water Detector will let you know when something in your house has sprung a leak, and when used with the Flo Smart Water Shutoff valve, it will prevent further damage by turning off your water supply.

Critical investors are able to determine company’s cash earnings.

Net flows into mutual funds that invest in equity fell 47 per cent to Rs 6,212 crore in April from Rs 11,722 crore in March, AMFI data showed.

Since, baking flours are flying off the shelves of grocery stores, we thought of saving some flour for our kitchen stock, and dug out these desert recipes that can be tried without using any kind of...

This morning, President Trump ordered American flags at all U.S. government buildings and facilities to be flown at half-staff until sunset on February 19, 2018 as a mark of solemn respect for the victims of the senseless act of violence in Florida. In concurrence with the President’s order and as an expression of Delaware’s sympathy […]

Agency: OMB Closing Date: 7/9/2020

Hospitals were not keen earlier and considered using UV lamps in the HVAC systems only because there was a 10-15% savings in the electricity bill and not because it improved air quality and killed microbes, Kulkarni said.

Two Indians, who were among the 363 brought back from Abu Dhabi and Dubai via special Air India flights that landed in Kerala on Thursday, have tested positive for the COVID-19 virus, the state...

DNREC is soliciting letters of interest to enter into projects that will support local resilience planning and adaptation activities in Delaware.

In a single day, there was a double-digit fall of 13.2% in Sensex—unprecedented in the past 16 years.

While debt funds saw sharp outflows, equity funds surprised the industry as it saw net inflows of Rs 11,722.74 crore in March — the highest in the current financial year.

Manchester City’s Kyle Walker has asked the media to end their “harassment” of him and his family for the sake of his mental health after AGAIN being caught flouting UK lockdown rules to collect home-cooked meals.
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