Various topologies of a quality of service application controller and related techniques to optimize the communications performance an application executing on a device participating in a communications environment are disclosed. The communications environment may include a cellular network, an unlicensed spectrum network, or a combination of the two. The quality of service application controller observes one or more key performance indicators of the communications network, and retrieves a policy from a policy store specific to the application. The quality of service application controller then modifies the execution of the application and/or the configurable aspects of the communications environment to optimize the communications performance of the application. For example, the application's data throughput may be increased, the power draw of the application may be minimized, data requested by the application may be minimized, or the apparent response time of the application's response to a web service may be minimized.

Compounds according to Formula I and Formula II are potent inhibitors of Arginase I and II activity: where R1, R2, R3, R4, R5, R6, R7, R8, R9, D, M, X, and Y are defined as set forth in the specification. The invention also provides pharmaceutical compositions of the compounds and methods of their use for treating or preventing a disease or a condition associated with arginase activity.

The present invention refers to a method for adjusting power levels of channels (15) in an optical link (7) of an optical network comprising at least one optical amplifier (9) wherein the power distribution among the channels (15) of the optical link (7) is achieved in function of: target power levels based on the features of corresponding connections and of link physical features,total available power in said at least one amplifier (9),features of control means allowing the power distribution, and wherein for a channel corresponding to a connection having a higher vulnerability characterizing parameter, the tolerated difference between an actual channel power level and the target power level is lower than for a channel corresponding to a connection having a lower vulnerability characterizing parameter.

A centrifuge to which sample tubes can be introduced while the centrifuge is in motion. The centrifuge comprises a carousel having an upper portion and a lower portion. The upper portion of the carousel has a plurality of positions for sample tubes for a centrifugation operation, a plurality of drive mechanisms attached to the upper portion of the carousel, a movable element mounted upon each drive mechanism, the movable element capable of traversing the length of the drive mechanism when the drive mechanism is actuated, a sample tube-holding assembly comprising a sample tube holder and a bearing attached to each movable element, and at least one balancing element capable of contributing to a force vector that cancels an imbalance vector generated by rotation of the centrifuge.

The present invention includes microfluidic systems having a microfabricated cavity that may be covered with a removable cover, where the removable cover allows at least part of the opening of the microfabricated cavity to be exposed or directly accessed by an operator. The microfluidic systems comprise chambers, flow and control channels formed in elastomeric layers that may comprise PDMS. The removable cover comprises a thermoplastic base film bonded to an elastomer layer by an adhesive layer. When the removable cover is peeled off, the chamber is at least partially open to allow sample extraction from the chamber. The chamber may have macromolecular crystals formed inside or resulting contents from a PCR reaction. The invention also includes a method for making vias in elastomeric layers by using the removable cover. The invention further includes methods and devices for peeling the peelable cover or a removable component such as Integrated Heater Spreader.

An apparatus for sampling and storing biological fluids from a human or animal subject is provided. In one embodiment of the present disclosure, the apparatus includes a main body, lancet carrier or hub, lancet, lancet trigger, capillary tube, and sample compartments for collecting and storing dried blood and other bodily fluids. The lancet hub supports a lancet and provides for moving the lancet longitudinally between a first retracted position and a second extended position. The device includes a capillary tube having an internal diameter sized to draw and retain fluid from a contacted source using capillary action. The main body of the apparatus further includes a sample compartment for holding sampling and storage materials. In at least one embodiment of the present disclosure, the sample compartment can be accessed by lifting sample compartment lid. Also included is a new “fan” or “daisy” shaped collection material format for use in collecting and preserving samples.

The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.

A power supply can provide brown-out protection and overheat protection. The power supply includes a rectifier, a transformer, and a power management device. The rectifier is used for receiving an alternating current voltage. The alternating current voltage has a voltage cycle. The transformer coupled to the rectifier has an inductor coupled to a switch for supplying an output voltage. The power management device is used for controlling the switch to make the inductor save power or release power. The power management device has a multi-functional pin coupled to the rectifier for receiving a detection voltage corresponding to a positive half cycle of the alternating current voltage. The multi-functional pin is also coupled to a thermistor for receiving an overheat protection signal.

A full bridge DC-DC converter to which a current doubler is applicable is provided and includes a transformer and a switching circuit that converts a high direct current voltage into a high alternating current voltage and then outputs the high alternating current voltage to the primary side of the transformer. In addition, an output circuit receives and processes the output of the secondary side of the transformer and supplies the processed output to an electric load. The output circuit includes a first inductor, a first contact resistor, a second inductor, a second contact resistor, a first diode, a third contact resister, a second diode, and a fourth contact resister.

A Low Forward Voltage Rectifier (LFVR) circuit includes a bipolar transistor, a parallel diode, and a capacitive current splitting network. The LFVR circuit, when it is performing a rectifying function, conducts the forward current from a first node to a second node provided that the voltage from the first node to the second node is adequately positive. The capacitive current splitting network causes a portion of the forward current to be a base current of the bipolar transistor, thereby biasing the transistor so that the forward current experiences a low forward voltage drop across the transistor. The LFVR circuit sees use in as a rectifier in many different types of switching power converters, including in flyback, Cuk, SEPIC, boost, buck-boost, PFC, half-bridge resonant, and full-bridge resonant converters. Due to the low forward voltage drop across the LFVR, converter efficiency is improved.

A splint system includes a first base member including at least one connector portion. A second base member including at least one connector portion having a cavity, wherein an interior surface of the cavity includes slidable portions and coupling portions, the first and second base members being aligned to form a longitudinal passage. A shaft member is disposed in the longitudinal passage, and when the coupling portions of the shaft member align with the coupling portions of the second base member, the first and second base members are fixed relative to each other.

A splint for use in stabilizing the nasal septum of a subject following the completion of a septoplasty procedure has a longitudinal axis and is formed of a substantially rigid sheet having a longitudinal length, an anterior end, and a posterior end. The sheet is labeled with a plurality of guide markings that guide a user in shaping the splint prior to implantation of the splint within a nasal passage of the subject.

A film structure having a polymer film and an application system enabling the film structure to be handled in a simple manner. The application system is arranged on a first side of the polymer film and has at least one supporting film to which at least one gripping strip is applied. The polymer film also has at least one first region without a supporting film.

The invention contemplates a copolymer which is a graft or block copolymer useful to change wettability and surface characteristics of biological surfaces. Methods for use of these formulations and coatings to change wettability and sterically stabilize, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to prevent adherence of unwanted proteins, for example in the treatment of contact lens intolerance, are provided.

An endoluminal support structure includes strut members interconnected by pivot joints to form a series of linked scissor mechanisms. The structure can be remotely actuated to compress or expand its shape by adjusting the scissor joints within a range of motion. In particular, the support structure can be repositioned within the body lumen or retrieved from the lumen. The support structure can be employed to introduce and support a prosthetic valve within a body lumen.

The invention discloses a novel method of controlling the open circuit potential (OCP) of a medical implant by coupling it with small amounts of metals having a lower OCP than the implant. Coupling of Mg to less than 1% of the surface area of a titanium implant is shown to induce cathodic polarization of the titanium that inhibits cell proliferation at the surface of the implant. Mg—Ti coupling in medical devices promises to attenuate or eliminate potential complications of surgery such as peri-implantitis and bacterial infections at the site of implantation.

A coupling means (10) provided with a first member (20) suitable for being fastened to a first rotary part (2) and with a second member (30) suitable for being fastened to a second rotary part (3), the first member (20) being provided with a first diaphragm (22) and the second member (30) being provided with a second diaphragm (32) that is secured to the first diaphragm (22). An emergency torque transmission device comprises at least one bayonet system including a protuberance (50) secured to one member (30) and co-operating with an angled groove (60) secured to the other member (20) by being inserted in the angled groove (60) by a thrust-and-rotation movement, in the absence of said breakage said coupling means (10) including both axial clearances in compression (70') and in translation (70″) and also circumferential clearance between each protuberance (50) and walls defining the corresponding angled groove (60).

A flexible shaft coupling demonstrates a high performance in transmitting torque and accommodating positional deviations, and is yet highly durable. A first elastomer member (82) having a relatively high rubber hardness is circumferentially interposed between a first claw (32) of a first shaft coupling member (20) and a second claw (62) of a second shaft coupling member (50), and a second elastomer member (84, 86) having a lower rubber hardness than the first elastomer member is interposed between a surface portion (end surface) (30) of the first shaft coupling member (20) and the second claw (62) and/or between a surface portion (end surface) (60) of the second shaft coupling member (50) and the first claw (32).

A coupling for connecting a rotating tube cleaning shaft to a tube cleaning machine where high pressure fluid is pumped through the coupling, where the coupling is sealed to contain the high pressure fluid, and where a machine driven rotary flexible shaft passes through the coupling.

A lock-up device for a fluid coupling suppresses vibration caused by coil springs. The lock-up device includes an input rotation member, an output rotation member, a plurality of first elastic members, and a float member. The plurality of first elastic members are compressed in a rotational direction by the relative rotation of the input rotation member and the output rotation member. The float member is rotatable relative to the input rotation member to cause two of the first elastic members to act in series in a circumferential direction.

An in-line coupling device for a motor driven agricultural system utilizes less metal components while optimizing torque transfer. The device comprises a puck having a plurality of outwardly extending arms, a first shaft hub having outwardly extending flanges adapted to seat between a pair of the plurality of outwardly extending arms, and a second shaft hub having outwardly extending flanges adapted to seat between a pair of the outwardly extending arms.

The purpose of the present invention is to provide novel liquid crystalline compounds that are capable of inducing phase transition by a light stimulus and are useful in the display, optoelectronics, and photonics field. The present invention relates to the liquid crystalline compounds represented by general formula (1): wherein R1, R2 and R3 are independently selected from the group consisting of hydrogen, alkyl, alkoxyl, alkoxycarbonyl, alkoxycarbonyloxy, alkanoyl, alkanoyloxy, alkoxyphenyl, and N-alkylaminocarbonyl, and n is an integer.

A video-on-demand (VOD) content delivery system has a VOD Application Server which manages a database of templates ordered in a hierarchy for presentation of video content elements of different selected types categorized in hierarchical order. The templates include those for higher-order displays which have one or more links to lower-order displays of specific content. The VOD Application Server, in response to viewer request, displays a high-order templatized display, and in response to viewer selection of a link, displays the lower-order display of specific content. The hierarchical templatized displays enable viewers to navigate to an end subject of interest while having a unique visual experience of moving through a series of displays to the end subject of interest. For example, the higher-order display may be a product ad and the lower-order display may be an ad for a local retailer of the product. Similarly, a viewer can navigate from national product to local product ad, or classified ad category to specific classified ad, or bulletin board topic category to specific posting. In another embodiment, the VOD content delivery system is used to deliver consumer-generated classified ads on TV. A web-based Content Management System receives consumer-generated content uploaded online in industry-standard file formats with metadata for title and topical area, and automatically converts it into video data format compatible with the VOD content delivery system indexed by title and topical area. A User Interface for the system delivers listings data to the viewer's TV indexed by title and topical area, and displays a requested classified ad in response to viewer selection.

Plant viral vectors have great potential in rapid production of proteins, but no simple. Here a geminivirus-based system for high-yield and rapid production of oligomeric protein complexes, including virus-like particle (VLP) vaccines and monoclonal antibodies (mAbs) is described. In particular, a single vector that contains two non-competing replicons for transient expression in Nicotiana benthamiana leaves is described. The correct assembly of these subunit proteins into functional oligomeric structures (VLPs or full-size mAb) is also described. This system advances plant transient expression technology by eliminating the need for non-competing viruses, and thus, enhances the realistic commercial application of this technology for producing multiple-subunit protein complexes.

A lightweight radio/CD player for vehicular application is virtually “fastenerless” and includes a case and frontal interface formed of polymer based material that is molded to provide details to accept audio devices such as playback mechanisms (if desired) and radio receivers, as well as the circuit boards required for electrical control and display. The case and frontal interface are of composite structure, including an insert molded electrically conductive wire mesh screen that has been pre-formed to contour with the molding operation. The wire mesh provides EMC, RFI, BCI and ESD shielding and grounding of the circuit boards via exposed wire mesh pads and adjacent ground clips. The PCB architecture is bifurcated into a first board carrying common circuit components in a surface mount configuration suitable for high volume production, and a second board carrying application specific circuit components in a wave soldered stick mount configuration. The major components and subassemblies are self-fixturing during the final assembly process, eliminating the need for dedicated tools, fixtures and assembly equipment. The major components and subassemblies self-interconnect by integral guide and connection features effecting “slide lock” and “snap lock” self-interconnection. The radio architecture includes improved push buttons employing 4-bar living hinge linkage and front loaded decorative trim buttons.

A lightweight radio/CD player for vehicular application includes a case and frontal interface formed of polymer based material molded to provide details to accept audio devices and radio receivers, as well as the circuit boards required for electrical control and display. The case and frontal interface are of composite structure, including an insert molded electrically conductive wire mesh screen that has been pre-formed to contour with the molding operation. The wire mesh provides shielding and grounding of the circuit boards via exposed wire mesh pads and adjacent ground clips.

A flow distribution system for use with a combine spreader having an inlet opening at the top thereof for receiving crop residue, a pair of counter-rotating spreader paddles disposed generally side by side and forward of a back plate of the spreader, and a discharge opening below the spreader paddles. A flow guide element has an apex portion and a pair of opposed arm portions pivotally connected to the apex portion, the arm portions laterally extending to free end portions. An adjusting mechanism is operably connected to the arm portions to effect rotational movement of the arm portions about the apex portion, ends of spreader paddle members defining the outer swept diameters of the pair of spreader paddles and the crop residue flow surfaces of at least the arm portions defining clearance regions therebetween to controllably distribute crop residue in a desired pattern over a field.

The present invention relates to the application of a force to enhance the performance of an electrochemical cell. The force may comprise, in some instances, an anisotropic force with a component normal to an active surface of the anode of the electrochemical cell. In the embodiments described herein, electrochemical cells (e.g., rechargeable batteries) may undergo a charge/discharge cycle involving deposition of metal (e.g., lithium metal) on a surface of the anode upon charging and reaction of the metal on the anode surface, wherein the metal diffuses from the anode surface, upon discharging. The uniformity with which the metal is deposited on the anode may affect cell performance. For example, when lithium metal is redeposited on an anode, it may, in some cases, deposit unevenly forming a rough surface. The roughened surface may increase the amount of lithium metal available for undesired chemical reactions which may result in decreased cycling lifetime and/or poor cell performance. The application of force to the electrochemical cell has been found, in accordance with the invention, to reduce such behavior and to improve the cycling lifetime and/or performance of the cell.

Methods and system for presenting a plurality of attributes of a plurality of players from a plurality of teams that are part of a league includes obtaining a plurality of attributes of the plurality of players and the plurality of teams. The plurality of attributes of the plurality of the players and of the teams is populated in one or more databases along with any updates to these attributes. The databases are queried to retrieve updated plurality of attributes of the plurality of players and the plurality of teams. A roster grid is generated for the plurality of teams for rendering at a client in substantial real time. The roster grid displays the updated status of the plurality of attributes of the plurality of players and the plurality of teams simultaneously in a clean, concise and effective manner.

A component instance manager of a database system generates an instance of the application function. The component instance manager then generates an executor for the application function, and requests an instance of a component class of the application function from a package manager of the database system. A void pointer associated with the instance of the component class and a wrapper function address associated with the application function are accessed by the component instance manager, where the void pointer and wrapper function address comprise runtime parameters of the application function. The application function is thereafter executed by the executor according to the runtime parameters.

System and methods are provided. In one embodiment, a system includes a master data archiver configured to store a data related to a turbomachine system and a first data collector service system configured to collect the data from the master data archiver. The system also includes a second data collector service system communicatively coupled to the first data collector system and configured to pull or to push the data from the first data collector system and a first data archiver configured to receive at least some of the data from the second data collector system. The system further includes an asset model database storing a plurality of turbomachine tags, wherein the turbomachine tags are configured to categorize the data and a data access system (DAS) configured to provide data access to the first data archiver, the asset model database, or a combination thereof.

Techniques are described for utilizing synchronous APIs which normally block callers until a result is returned. In particular, the techniques described herein enable an application or other programming construct to boost performance by executing synchronous APIs (e.g., long running time APIs) within a proxy container rather than executing the synchronous APIs in the context of the application itself. Since the proxy is a separate process or thread, the caller application is thereby released from waiting for the synchronous API call and may proceed with other processing instead of waiting for the synchronous API to return. The application may then monitor the proxy to determine whether a result has been received, such as by periodically polling the proxy.

An exemplary method includes a broker-based messaging system detecting a request provided by a software application for the software application to connect to any one of a plurality of brokers included in a cluster of brokers, dynamically identifying, in response to the request and in accordance with a connection distribution heuristic, a broker included in the cluster of brokers and that is available for connection to the software application, and attempting to establish a connection between the software application and the broker. Corresponding methods and systems are also disclosed.

A system, method, and computer readable medium for asynchronous live migration of applications between two or more servers. The computer readable medium includes computer-executable instructions for execution by a processing system. Primary applications runs on primary hosts and one or more replicated instances of each primary application run on one or more backup hosts. Asynchronous live migration is provided through a combination of process replication, logging, barrier synchronization, checkpointing, reliable messaging and message playback. The live migration is transparent to the application and requires no modification to the application, operating system, networking stack or libraries.

An application gateway enables controlled communication between application components within a browser based environment while maintaining a level of isolation of the individual application components. A dispatching API wrapper and a listening API wrapper are registered for each of a plurality of application components. The registered API wrappers are used to send and receive communications from the associated application components. For example, a first application component can dispatch an action to a second application component via the first application component's dispatching API wrapper. The second application component can receive the action via the second application component's listening API wrapper. As another example, a first application component can dispatch an event that broadcasts a state to other application components via the first application component's dispatching API wrapper. A listening API wrapper of at least one other application component receives the state and may perform other functions dependent on the state.

A method and a processing device may be provided for state management of an operating system and applications. A framework may be provided for separating behaviorless state information from code or instructions for executing a method. Applications may have instances of state information derived from, or completely different from, instances of state information of an operating system. Instances of state information for an application may be layered over corresponding instances of state information of the operating system, such that the application and the operating system may have different views of the instances of the state information. At least one policy may be defined, which may include rules for resolving conflicts, information for providing a merged view of data from multiple repositories, default values for instances of data, as well as other information. In various implementations, referential integrity of state information may be guaranteed.

According to one embodiment of the present disclosure, interfacing between a plurality of applications for display on a mobile device includes receiving, by an interface, a request to open a plurality of applications. The plurality of applications are associated with a plurality of business units and comprise one or more native applications and one or more web applications. A processor opens the plurality of applications in a container according to a configuration file. The processor is communicatively coupled to the interface. The container is operable to be displayed on a user interface of the mobile device.

A dispatcher framework to provide non-blocking inter-application communication is disclosed. In various embodiments, a call to a service that is blocking with respect to the service is received from a calling process. The service is called on behalf of the calling process in a manner that does not require the calling process to remain blocked during at least a portion of a time during which the call to the service is performed.

A mobile thermoplastic applicator comprises a kettle, a main gas burner, a heat exchanger plenum, and a screed die box. The kettle has walls which define an interior space for melting thermoplastic. The main gas burner is situated beneath the kettle, and is configured to heat the kettle. The heat exchanger plenum is situated inside the thermoplastic kettle and is configured to subdivide the interior space and circulate heated air from the main gas burner. The screed die box is configured to receive molten thermoplastic from the kettle and deposit that molten thermoplastic on a surface.

A pen dispenser for dispensing flowable and non-flowable material, comprising a pen body and an optional push button applicator for the pen, a universal cartridge, optionally having a disposable cartridge, and capable of accepting a multitude of interchangeable tip applicators.

A heated cosmetic applicator that has a plurality of small, individual heating elements placed within and/or on at least some of the lash grooming elements. A heat-generating applicator head for a heated cosmetic applicator that has a plurality of small, individual heating elements placed within and/or on at least some of the lash grooming elements.

A makeup applicator assembly includes an elongated tube having an interior space, a bottom end and a top end. A bottom opening extends through the bottom end of the tube. A chamber is positioned in the interior space and the chamber is positioned proximate the bottom end of the tube. A makeup material is positioned in the chamber. An elongated applicator is also positioned in the chamber. A button is coupled to and extends from the top end of the tube. A plunger extends between the button and the applicator, and the plunger also extends into the chamber. A dispensing aperture is positioned in the chamber. The applicator is extendable through the dispensing aperture. The dispensing aperture is positioned proximate the bottom end of the tube wherein the applicator is extendable from the bottom end of the tube when the button is manipulated.

A packaging and applicator device for applying a composition on the eyelashes and/or the eyebrows, that includes a container defining an inside space containing the composition and including a wiper member; and an applicator having a longitudinal axis and having an applicator member with a twisted-core brush carrying bristles, there being 5 to 55 bristles per turn, the diameter of the brush lying in the range 6/100 mm to 40/100 mm along at least a fraction of the applicator member, a plurality of bristles carried by this portion coming to within a distance of less than 1.5 mm from the inside surface of the container under the wiper member in a storage position or while the applicator is being withdrawn along the longitudinal axis of the container.

A cream dispensing applicator assembly allows an individual to easily, evenly, and cleanly apply cream to hard-to-reach areas of the body. The assembly includes an elongated member having a head coupled to a handle. The elongated member has an interior space configured for holding a liquid. A pad is coupled to the head. A channel extends through the head. A plurality of outlet ports is coupled to the pad and to the channel. A plunger, a shaft, a knob, and a switch are coupled to the handle. The shaft is coupled to and extends through the plunger. The knob is operationally coupled to the plunger wherein manipulation of the knob urges the plunger into the shaft. A valve is coupled to the handle and to the channel. The switch is operationally coupled to the valve wherein manipulation of the switch selectively opens and closes the valve.

A container (1) for a stick of a cosmetic or hygienic product, comprising an applicator element (3) in which a stick (2) of said product can move axially relative to a base (32), as well as a tubular storage element (4) comprising a top (41) that contains a mobile sleeve (42) and is suitable for covering the applicator element (3) in a configuration wherein said applicator element is fully inserted into the sleeve and connected to said top by means of an elastically compressible device having two stable axial positions relative to a hilly inserted configuration, said device comprising a resilient element (43) pushing the sleeve (42) towards the outside of the top, and, distributed between the top and the sleeve, a heart-shaped guide track (44) arranged parallel to an axial direction of the top, and a follower (45) carried by a generally axially pivoting arm (46) such as to define stable top and bottom positions allowing the applicator element to be gripped or not. The resilient element (43) is arranged between the outer wall of the sleeve (42) and the inner wall of the top (41), and the guide track and follower are arranged in a lateral space formed by the shape differences of the cross-sections of the top and the sleeve.

An application device for applying a flowable substance includes an outer shell, and inner shell, and a reservoir defined between the inner and outer shells. The outer shell has an outer circumferential wall and an outer bottom. The inner shell has an inner circumferential wall and an inner bottom defining an inner space and is sealingly received in the outer shell for telescopic movement between a closed position and a released position. At least one orifice is formed in the inner bottom of the inner shell. A closure means closes off the at least one orifice in the closed position, wherein at least one pin forming at least part of the closure means extends from the outer shell.

A plurality of multi-applicator tools are provided, including tools which include magnetically attachable and detachable application brushes or the like. Some embodiments include a linear arrangement of brushes in a generally elongate tool configuration. Other embodiments include a central base into which application brushes fit within. Various appearances are likewise provided.

Applicators are described suitable for the application of liquid to patient's skin. An applicator pad (3) is supported on a support flange (23) of an applicator housing (2), which receives a liquid cartridge (5). To moderate the rush of liquid on to the back of the applicator pad a flow distributor plate (6) is positioned on the rear position of the pad (3), restricting flow onto the pad to an annular slit opening around the plate (6). The front surface of the plate (6), opposing the pad (3), may have one or more grooves so that liquid can flow from the edge towards the center. Also disclosed, as an alternative, is the use of a projecting cantilevered tongue structure to distribute liquid across the rear surface of the sponge pad. The pad may have a hooked lobe shape for a front end of the applicator pad.

A unitary hand-held, single-use liquid dispenser and applicator is disclosed. A squeezable handle also serves as a reservoir for liquid. A non-forming thermoplastic film seals liquid within the reservoir. Novel weaknesses in the film can be broken on demand to create an opening for liquid to freely flow onto an absorbent pad. A user can thus dispense and apply the liquid without ever touching the liquid or the surface with his hands.

The present invention relates to an applicator for applying a composition to keratinous fibers, in particular the eyelashes or the eyebrows, the applicator including a stem having a longitudinal axis and including at least one elastically-deformable flexible portion that is suitable for flexing during application and/or wiping; and an applicator element that is fastened to the stem and that includes a twisted wire core and bristles that extend transversally to the longitudinal axis of the stem.