not The Raj & DK Line-Up You Cannot Miss By www.rediff.com Published On :: Sukanya Verma looks at their eclectic career of over two decades as their latest offering Citadel: Honey Bunny, the Indian leg of the Russo Brothers globetrotting spy universe series, drops on Amazon Prime Video on November 7. Full Article
not Azo derivatives of monoterpenes as anti-Helicobacter pylori agents: from synthesis to structure-based target investigation By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00511B, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Francesco Melfi, Marialuigia Fantacuzzi, Simone Carradori, Ilaria D'Agostino, Alessandra Ammazzalorso, Noemi Mencarelli, Marialucia Gallorini, Mattia Spano, Paolo Guglielmi, Mariangela Agamennone, Sazan Haji Ali, Ali Al-Samydai, Francesca SistoMonoterpene-derived azo benzenes showed selective antibacterial activity against Helicobacter pylori with a safe profile. An in silico investigation highlighted the inosine 5'-monophosphate dehydrogenase enzyme as the putative target.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
not Ligand-centred phenotype-driven development of potent kinase inhibitors against oesophageal cancer By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00579A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Cecilia C. Ayala-Aguilera, Yang Ge, Álvaro Lorente-Macías, Benjamin N. Jones, Catherine Adam, Neil O. Carragher, Asier Unciti-BrocetaA ligand-centred strategy combined with phenotypic screening was used to develop novel antiproliferative inhibitors against oesophageal cancer and identified a lead compound that induces potent anticancer activity and inhibits Aurora kinase A.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
not meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00601A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza GainaNew meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
not Changes in train services notified due to demolition of old bridge near Tiruchi junction By www.thehindu.com Published On :: Tue, 05 Nov 2024 17:30:53 +0530 Full Article Tiruchirapalli
not EPS’s dream of AIADMK staging a comeback in 2026 election will not materialise: Law Minister Regupathy By www.thehindu.com Published On :: Fri, 08 Nov 2024 20:25:59 +0530 Full Article Tiruchirapalli
not 631: Dave’s Second Brain Idea, Notion Thoughts, and Google’s LLM in Chrome By shoptalkshow.com Published On :: Mon, 02 Sep 2024 08:01:07 +0000 Dave's got an idea for a second brain app that's customized to his brain, where we're at with Notion and other notes apps, and accessibility on LLM's in browsers. Full Article All Episodes Chrome LLM notion second brain
not Jamiat cautions NDA partners, says ‘crutches’ cannot escape responsibility for Waqf Bill By www.thehindu.com Published On :: Mon, 04 Nov 2024 21:07:19 +0530 The Jamiat Ulama-i-Hind urged NDA partners TDP and JD(U) to heed Muslim sentiments on the contentious issue surrounding the Waqf (Amendment) Bill, 2024 Full Article India
not Cannot change rules of the game once recruitment to public services commences: SC By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:49:04 +0530 The Constitution Bench says laws, rules and procedure governing recruitments to public services must be governed by the overarching principles of fundamental rights of equality and non-discrimination Full Article India
not Delhi HC permits man to buy The Satanic Verses after Centre fails to produce notification banning the book By www.thehindu.com Published On :: Thu, 07 Nov 2024 20:30:42 +0530 India was one of the first countries to ban the book’s import and sale, citing concerns over its content being offensive to the Muslim community Full Article India
not Issue of infiltration in Santhal Pargana was raised, Hemant did not listen: Champai Soren By www.thehindu.com Published On :: Fri, 08 Nov 2024 21:53:12 +0530 The longtime JMM-loyalist, who has now switched to the BJP, adds that decisions he had taken as CM — on tribal language education, PESA implementation, and jump-starting state recruitments — have been put on hold now Full Article Jharkhand Assembly
not Man stabs mother in Delhi’s Badarpur for not ‘allowing him’ to migrate to Canada By www.thehindu.com Published On :: Sun, 10 Nov 2024 00:37:44 +0530 Full Article Delhi
not Why it’s important to do nothing By www.thehindubusinessline.com Published On :: Mon, 22 Jun 2020 07:11:00 +0530 Jenny Odell’s take on avoiding the seduction of the online world is a must-read for Covid times Full Article Books
not Nanoscience is not just a fad By www.thehindubusinessline.com Published On :: Sun, 30 Aug 2020 20:47:53 +0530 In Nanoscale, Pankaj Sekhsaria explores the transformative powers of nanoscience in Indian society Full Article Books
not Why gas is not just hot air By www.thehindubusinessline.com Published On :: Sun, 30 May 2021 20:38:37 +0530 Full Article Books
not MSP law cannot be brought in a hurry; farmers should come forward for talks with govt: Arjun Munda By www.thehindu.com Published On :: Tue, 13 Feb 2024 17:35:17 +0530 Union Agriculture Minister Arjun Munda cautioned protesting farmers about some elements usurping their protest for political benefits Full Article Agriculture
not SC notice to Centre on plea alleging overuse of pesticides on crops and food items By www.thehindu.com Published On :: Sat, 18 May 2024 16:51:00 +0530 Full Article India
not If it was not for Pandya... By www.rediff.com Published On :: Thu, 03 Dec 2020 14:04:28 +0530 Purnendu Maji and Srinivas Bhogle list the Most Valuable Players during the India-Australia ODI series. Full Article ODI MVPI Steve Smith Hardik Pandya Jasprit Bumrah Glenn Maxwell IMAGE Purnendu Maji Srinivas Bhogle Yuzvendra Chahal Ravindra Jadeja Australia-India Australia Aslam Rediff India-Australia
not BSE sends notice to 509 suspended firms By www.thehindu.com Published On :: Mon, 06 Jun 2016 00:00:00 +0530 Bourse asks companies to either apply for revocation of suspension or opt for delisting Full Article Mumbai Capital
not Rupee opens on flat note, rises 1 paisa to 84.07 against U.S. dollar in early trade By www.thehindu.com Published On :: Thu, 31 Oct 2024 10:20:32 +0530 The rupee rises slightly against dollar amid strong dollar and foreign fund outflows; RBI intervention expected to support local currency Full Article Markets
not Rupee settles on flat note, rises 1 paisa to 84.07 against U.S. dollar By www.thehindu.com Published On :: Thu, 31 Oct 2024 16:24:23 +0530 Meanwhile, the dollar index, which gauges the greenback's strength against a basket of six currencies, was trading 0.08% lower at 103.91 Full Article Markets
not Kamal Haasan tells people, fans to not address him as ‘Ulaganayagan’ By www.thehindu.com Published On :: Mon, 11 Nov 2024 12:02:57 +0530 The star also requested his fans, members of the film fraternity, media, party cadres and ‘fellow Indians’ to refer to him ‘simply as Kamal Haasan or Kamal or KH’ Full Article Movies
not Kanguva cannot be released without depositing ₹20 crore: Madras High Court By www.thehindu.com Published On :: Tue, 12 Nov 2024 19:40:17 +0530 Justices G. Jayachandran and C.V. Karthikeyan pass the order on an application filed by the Official Assignee of the High Court Full Article Tamil Nadu
not Cell shape and orientation control galvanotactic accuracy By pubs.rsc.org Published On :: Soft Matter, 2024, Advance ArticleDOI: 10.1039/D4SM00952E, PaperIfunanya Nwogbaga, Brian A. CamleyWe study the physical factors that control the accuracy with which elongated cells can sense the direction of an electric field, exploring whether cells are more accurate sensors when oriented parallel to the field or perpendicular to it.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
not Retraction: Self-assembled organic nanotubes embedding hydrophobic molecules within solid bilayer membranes By pubs.rsc.org Published On :: Soft Matter, 2024, Advance ArticleDOI: 10.1039/D4SM90171A, Retraction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Naohiro Kameta, Masumi Asakawa, Mitsutoshi Masuda, Toshimi ShimizuTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
not Retraction: Supramolecular organic nanotubes: how to utilize the inner nanospace and the outer space By pubs.rsc.org Published On :: Soft Matter, 2024, Advance ArticleDOI: 10.1039/D4SM90172J, Retraction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Naohiro Kameta, Hiroyuki Minamikawa, Mitsutoshi MasudaTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
not Z’s Still Not Dead Baby, Z’s Still Not Dead By 24ways.org Published On :: Tue, 10 Dec 2019 12:00:00 +0000 Andy Clarke digs deep into snow to find ways flat design can be brought back to life in CSS with the use of techniques to create a sense of depth. Like spring after an everlasting winter, perhaps it’s time to let a different style of design flourish. What a relief. A reaction to overly ornamental designs, flat design has been the dominant aesthetic for almost a decade. As gradients, patterns, shadows, and three-dimensional skeuomorphism fell out of fashion, designers embraced solid colours, square corners, and sharp edges. Anti-skeuomorphism no doubt helped designers focus on feature design and usability without the distraction of what some might still see as flourishes. But, reducing both product and website designs to a bare minimum has had unfortunate repercussions. With little to differentiate their designs, products and websites have adopted a regrettable uniformity which makes it difficult to distinguish between them. Still, all fashions fade eventually. I’m hopeful that with the styling tools we have today, we’ll move beyond flatness and add an extra dimension. Here are five CSS properties which will bring depth and richness to your designs. To illustrate how you might use them, I’ve made this design for the 1961 Austin Seven 850, the small car which helped define the swinging sixties. The original Mini. Red, (British Racing) green, blue designs. Transparency with alpha values The simplest way to add transparency to a background colour, border, or text element is using alpha values in your colour styles. These values have been available in combination with RGB (red, green, blue) for years. In RGBA, decimal values below 1 make any colour progressively more transparent. 0 is the most transparent, 1 is the most opaque: body { color: rgba(255, 0, 153, .75); } Alpha values allow colour from a background to bleed through. Alpha values also combine with HSL (hue, saturation, lightness) to form HSLA: body { color: hsla(0, 0, 100, .75); } Currently a Working Draft, CSS Color Module Level 4 enables alpha values in RGB and HSL without the additional “A”: body { color: rgb(255, 0, 153, .75); /* color: hsl(0, 0, 100, .75); */ } This new module also introduces hexadecimal colours with alpha values. In this new value, the last two digits represent the transparency level, with FF producing 100% opacity and 00 resulting in 100% transparency. For the 75% opacity in my design, I add BF to my white hexadecimal colour: body { color: #ffffffbf; } Although there’s already wide support for hexadecimal, HSL, and RGB with alpha values in most modern browsers, the current version of Microsoft Edge for Windows has lagged behind. This situation will no doubt change when Microsoft move Edge to Chromium. 2. Use opacity Using the opacity property specifies the amount of opacity of any element (obviously) which allows elements below them in the stacking order to be all or partially visible. A value of 0 is most transparent, whereas 1 is most opaque. Opacity tints images with colour from elements behind them. This property is especially useful for tinting the colour of elements by allowing any colour behind them to bleed through. The British Motor Corporation logo in the footer of my design is solid white, but reducing its opacity allows it to take on the colour of the body element behind: [src*="footer"] { opacity: .75; } You might otherwise choose to use opacity values as part of a CSS filter. 0% opacity is fully transparent, while 100% is fully opaque and appears as if no filter has been applied. Applying a CSS filter is straightforward. First, declare the filter-function and then a value in parentheses: [src*="footer"] { filter: opacity(75%); } 3. Start blending Almost universally, contemporary browsers support the same compositing tools we’ve used in graphic design and photo editing software for years. Blend modes including luminosity, multiply, overlay, and screen can easily and quickly add depth to a design. There are two types of blend-mode. background-blend-mode defines how background layers blend with the background colour behind them, and with each other. My layered design requires three background images applied to the body element: body { padding: 2rem; background-color: #ba0e37; background-image: url(body-1.png), url(body-2.png), url(body-3.png); background-origin: content-box; background-position: 0 0; background-repeat: no-repeat; background-size: contain; } From left: Three background images. Far right: How images combine in a browser. You can apply different background-blend modes for each background image. Specify them in the same order as your background images and separate them with a comma: body { background-blend-mode: multiply, soft-light, hard-light; } Six background-blend-mode variations. When I need to apply an alternative colour palette, there’s no need to export new background assets. I can achieve results simply by changing the background colour and these background-blend modes. Backgrounds blend behind this brilliant little car. Sadly, there’s not yet support for blending modes in Edge, so provide an alternative background image for that browser: @supports not (background-blend-mode: normal) { body { background-image: url(ihatetimvandamme.png); } } mix-blend-mode, on the other hand, defines how an element’s content should blend with its ancestors. From left: Screen, overlay, and soft-light mix-blend-mode. To blend my Mini image with the background colours and images on the body, I add a value of hard-light, plus a filter which converts my full-colour picture to greyscale: [src*="figure"] { filter: grayscale(100%); mix-blend-mode: hard-light; } You can also use mix-blend-mode to add depth to text elements, like this headline and large footer paragraph in a green and yellow version of my design: .theme-green h1, .theme-green footer p:last-of-type { color: #f8Ef1c; mix-blend-mode: difference; } Text elements blend to add interest in my design. 4. Overlap with CSS Grid Whereas old-fashioned layout methods reinforced a rigid structure on website designs, CSS Grid opens up the possibility to layer elements without positioning or resorting to margin hacks. The HTML for my design is semantic and simple: <body> <p>You’ve never seen a car like it</p> <h1><em>1961:</em> small car of the year</h1> <figure> <img src="figure.png" alt="Austin Seven 850"> <figcaption> <ul> <li>Austin Super Seven</li> <li>Morris Super Mini-Minor</li> <li>Austin Seven Cooper</li> <li>Morris Mini-Cooper</li> </ul> <figcaption> </figure> <footer> <p>Today’s car is a Mini</p> <p>Austin Seven 850</p> <img src="footer.png" alt="Austin Seven 850"> <footer> </body> I begin by applying a three-column symmetrical grid to the body element: @media screen and (min-width : 48em) { body { display: grid; grid-template-columns: 1fr 1fr 1fr; } } Three-column symmetrical grid with column and row lines over my design. Then, I place my elements onto that grid using line numbers: body > p { grid-column: 1 / -1; } h1 { grid-column: 1 / 3; } figure { grid-column: 1 / -1; } footer { display: contents; } footer div { grid-column: 1 / 3; } [src*="footer"] { grid-column: 3 / -1; align-self: end; } As sub-grid has yet to see wide adoption, I apply a second grid to my figure element, so I may place my image and figcaption: figure { display: grid; grid-template-columns: 1fr 3fr; } figcaption { grid-column: 1; } [src*="figure"] { grid-column: 2; } Left: This conventional alignment lacks energy. Right: Overlapping content adds movement which makes my design more interesting overall. Previewing the result in a browser shows me the energy associated with driving this little car is missing. To add movement to my design, I change the image’s grid-column values so it occupies the same space as my caption: figcaption { grid-column: 1; grid-row: 3; } [src*="figure"] { grid-column: 1 / -1; grid-row: 3; padding-left: 5vw; } 5. Stack with z-index In geometry, the x axis represents horizontal, the y axis represents vertical. In CSS, the z axis represents depth. Z-index values can be either negative or positive and the element with the highest value appears closest to a viewer, regardless of its position in the flow. If you give more than one element the same z-index value, the one which comes last in source order will appear on top. Visualisation of z-index illustrates the depth in this design. It’s important to remember that z-index is only applied to elements which have their position property set to either relative or absolute. Without positioning, there is no stacking. However, z-index can be used on elements placed onto a grid. All techniques combined to form a design which has richness and depth. As the previous figure image and figcaption occupy the same grid columns and row, I apply a higher z-index value to my caption to bring it closer to the viewer, despite it appearing before the picture in the flow of my content: figcaption { grid-column: 1; grid-row: 3; z-index: 2; } [src*="figure"] { grid-column: 1 / -1; grid-row: 3; z-index: 1; } Z’s not dead baby, Z’s not dead While I’m not advocating a return to the worst excesses of skeuomorphism, I hope product and website designers will realise the value of a more vibrant approach to design; one which appreciates how design can distinguish a brand from its competition. I’m incredibly grateful to Drew and his team of volunteers for inviting me to write for this incredible publication every year for the past fifteen years. As I closed my first article here on this day all those years ago, “Have a great holiday season!” Z’s still not dead baby, Z’s still not dead. About the author Andy Clarke is one of the world’s best-known website designers, consultant, speaker, and writer on art direction and design for products and websites. Andy founded Stuff & Nonsense in 1998 and for 20 years has helped companies big and small to improve their website and product designs. Andy’s the author of four web design books including ‘Transcending CSS,’ ‘Hardboiled Web Design’ and ‘Art Direction for the Web’. He really, really loves gorillas. More articles by Andy Full Article Design design
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