Pat O'Neil, an Indiana Baseball Hall of Fame inductee, was declared cancer-free Tuesday.

Some families have said that they were denied free internet access, offered in response to the coronavirus, because of old debts.

Colts continue adding players after NFL Draft.

"Every team in this league has holes."

A high schooler launched an idea to deliver groceries and help small businesses.

Long Beach police alerted the CHP to the man, who was walking on the freeway about 1:30 a.m. and wielding a knife.

A bear in Castaic was fatally struck by a car while walking through traffic near the northbound 5 Freeway the early Friday morning hours.

Eventual vaccine developed to fight COVID-19 should be free to everyone, a letter to the editor says.

As the tulips begin to bloom across Ottawa, the National Capital Commission now says you can stop and take a photo of the colourful flowers.

The tome will be written by CNN's East Wing correspondent, Kate Bennett.

How can you get free things on your next cruise, and get much more bang for your cruising bucks? I discuss the 6 main areas of cruise freebies that are available, if you go and ask for them or seek them out. They are not things that cruise brochures and websites usually reveal, or talk about. I tell you the things to focus on and how to get as many free things as you possibly can, including drinks, special food, gifts, spa treatments, better and improved cabins and more.

** Buy my Cruise T-shirts: http://bit.ly/TFTStore
** USA cruisers get great cruise deals CRUISEDIRECT.COM: http://bit.ly/TFTBookCruise
** UK Cruisers get great cruise deals with CRUISE.CO.UK: http://bit.ly/BookCruiseUK

Gary Bembridge's Tips For Travellers aims to help you make more of your precious travel time and money on land and when cruising the oceans or rivers of the world. To help you, in every video I draw on my first-hand tips and advice from travelling every month for over 20 years and 60+ cruises.

Follow Tips For Travellers on:
- Instagram: http://www.instagram.com/garybembridge
- Facebook: http://www.facebook.com/tipsfortravellers
- Twitter: http://www.twitter.com/garybembridge

What are the 8 best things you can do on Norwegian Encore cruise ship for free, as they are included within your cruise fare? Norwegian Encore launched in November 2019 and, like the rest of the Norwegian Cruise Line fleet, has lots of choice and facilities. However, many of these do costs a fee above your cruise fare to use, including some restaurants, activities and facilities. So, I reveal what the very best things you can do on board Norwegian Encore that you do not have to pay extra to do. Some, I hope will surprise and please you!

Note: I travelled as a guest of the cruise line before making this video on a short shakedown cruise before the ship went to fare-paying passenger service

SUPPORT THE CHANNEL BY:
Buying my Cruise T-shirts: http://bit.ly/TFTStore
Booking your next cruise with CRUISEDIRECT.COM: http://bit.ly/TFTBookCruisE

Gary Bembridge's Tips For Travellers aims to help you make more of your precious travel time and money on land and when cruising the oceans or rivers of the world. To help you, in every video I draw on my first-hand tips and advice from travelling every month for over 20 years and 60+ cruises.

Follow Tips For Travellers on:
- Instagram: http://www.instagram.com/garybembridge
- Facebook: http://www.facebook.com/tipsfortravellers
- Twitter: http://www.twitter.com/garybembridge

TVover.net and Echo Communications are giving away 2 free Expo passes to TelcoTV 2012, Ocotber 24-26, 2012 in Las Vegas, NV, USA. The Expo pass gives you access to Exhibit Hall, Keynotes, and Vendor-Hosted Workshops. For mroe information about TelcoTV 2012 and registration, click here.

Enter to win by emailing us at media@tvover.net with subject line 'TelcoTV 2012 raffle', name, email, company, address and phone number by noon CST, October 21, 2012. The winner will be randomly drawn.

They know more than anyone how difficult it is to get funding for colleges.

It’s rather unfortunate that the best some of us can do in a time of a global pandemic is to stay at home in order to help. Quarantines for that matter, are tough challenges for the regular person. However, they don’t have to feel like an unproductive slog, why not treat yourself to some self-improvement […]

The post 12 Free Web Development Courses to Take While in Self-Isolation appeared first on SpyreStudios.

oscon: Watch our free #opensource webcast series coming in June- #python #linux #raspberrypi #go + more http://t.co/ru0LVl20gq #oscon

Join us online for SMX Next, a free virtual event designed to equip you with actionable SEO and SEM tactics that can drive more traffic, leads, and sales.

Please visit Search Engine Land for the full article.

velocityconf: Free webcast w/ @jon lives http://t.co/TxL60Oagos 'Michelin Starred Cooking with Chef at Etsy' starting NOW. #velocityconf #devops

velocityconf: Help your dev + ops teams be cross-functional and more successful. http://t.co/1mqGK3zh0U Free webcast 5/22 w/ @lnxchk

velocityconf: Free webcast from our friends at @citrix 5/29 http://t.co/IOeY4U0wUP Learn to consolidate 40 load balancers and ADCs into single platform

"We're writing off too many people," Rep. Mick Mulvaney (R-SC) says in "Immigration Battle," a feature film presentation from FRONTLINE and Independent Lens that airs tonight on PBS.

The internet is a scary enough place as it is, and now with the added misinformation and panic surrounding the coronavirus pandemic, it's even scarier. Thanks to the United Nations and dozens of artists, however, the internet just got a little more beautiful. 

In late March, the UN put a call out to artists to help combat the spread of COVID-19. They sought creatives to create content around six areas of WHO and UN priority actions: personal hygiene, social distancing, knowing the symptoms, spreading kindness, myth-busting, and doing more/donating. Tens of thousands of artists answered the call in two weeks, and now the COVID-19 Response Creative Content Hub is available for browsing.  Read more...

Freeman Dyson died last week at the age of 96 after injuring himself in a fall in the cafeteria at the Institute of Advanced Studies in Princeton, where he had continued to work right up to the end. I can’t resist adding to the outpouring of appreciation and love that has ensued. He has an […]

Decision-making can be tough especially when the best choice isn’t glaringly obvious. We’re faced with this process every minute of the day. When do I wake up? What’s for lunch? Do I want to go out on a date with this person? What do I want to do with my life? Can I stay in […]

The post Stop Losing Sleep: 7 Steps for Stress-free Decision-making appeared first on Dumb Little Man.

The following article, Legal Immigrant in Michigan Sends a Message to MI Gov Whitmer and Media Criticizing Freedom-Loving Protesters, was first published on 100PercentFedUp.com.

The media and even some governors are trying to paint the Americans who are protesting to open businesses up as racists and even Nazis. The Governor of Michigan recently made a derogatory statement about the protesters implying they are racists. Painting a negative picture of the people who want their freedom and businesses demonizes our […]

Continue reading: Legal Immigrant in Michigan Sends a Message to MI Gov Whitmer and Media Criticizing Freedom-Loving Protesters ...

The following article, Texas Gov Abbott Frees Salon Owner Shelley Luther: “Criminals shouldn’t be released to prevent COVID-19 just to put business owners in their place”, was first published on 100PercentFedUp.com.

Texas Governor Greg Abbott just changed the coronavirus order to free Salon A La Mode owner Shelley Luther from jail. Abbott tweeted out a comment about the poor treatment of the business owner: Throwing Texans in jail whose biz’s shut down through no fault of their own is wrong. I am eliminating jail for violating […]

Continue reading: Texas Gov Abbott Frees Salon Owner Shelley Luther: “Criminals shouldn’t be released to prevent COVID-19 just to put business owners in their place” ...

William M. Old
Oct 1, 2005; 4:1487-1502
Research

Jürgen Cox
Sep 1, 2014; 13:2513-2526
Technological Innovation and Resources

Actinobacillus pleuropneumoniae (App) is the etiological agent of acute porcine pneumonia and responsible for severe economic losses worldwide. The capsule polymer of App serotype 1 (App1) consists of [4)-GlcNAc-β(1,6)-Gal-α-1-(PO4-] repeating units that are O-acetylated at O-6 of the GlcNAc. It is a major virulence factor and was used in previous studies in the successful generation of an experimental glycoconjugate vaccine. However, the application of glycoconjugate vaccines in the animal health sector is limited, presumably because of the high costs associated with harvesting the polymer from pathogen culture. Consequently, here we exploited the capsule polymerase Cps1B of App1 as an in vitro synthesis tool and an alternative for capsule polymer provision. Cps1B consists of two catalytic domains, as well as a domain rich in tetratricopeptide repeats (TPRs). We compared the elongation mechanism of Cps1B with that of a ΔTPR truncation (Cps1B-ΔTPR). Interestingly, the product profiles displayed by Cps1B suggested processive elongation of the nascent polymer, whereas Cps1B-ΔTPR appeared to work in a more distributive manner. The dispersity of the synthesized products could be reduced by generating single-action transferases and immobilizing them on individual columns, separating the two catalytic activities. Furthermore, we identified the O-acetyltransferase Cps1D of App1 and used it to modify the polymers produced by Cps1B. Two-dimensional NMR analyses of the products revealed O-acetylation levels identical to those of polymer harvested from App1 culture supernatants. In conclusion, we have established a protocol for the pathogen-free in vitro synthesis of tailored, nature-identical App1 capsule polymers.

8 January 2020 , Volume 96, Number 1

7 May 2020 , Volume 96, Number 3

Invitation Only

Event participants

Leandro Prados de la Escosura, Professor, Economic History, Universidad Carlos III de Madrid 

1 February 2014

Substantial gains in world human development have been achieved since 1870, but research shows that the main improvement actually occurred between the First World War and 1970.

Under 35s Forum

Event participants

Invitation Only Research Event

Event participants

Tunç Aybak, Programme Leader, International Politics and Law, Middlesex University
Thomas de Waal, Senior Associate, Russia and Eurasia Program, Carnegie Endowment for International Peace
Hratch Tchilingirian, Associate Faculty Member, Faculty of Oriental Studies, University of Oxford

Research Event

Event participants

Sherif Elsayed-Ali, Head of Technology and Human Rights, Amnesty International
Professor David Kaye, UN Special Rapporteur on the Promotion and Protection of the Right to Freedom of Opinion and Expression
Chair: Sonya Sceats, Associate Fellow, International Law Programme, Chatham House

Jennifer L. Macdonald
May 1, 2005; 46:1061-1067
Methods

W Gamble
Nov 1, 1978; 19:1068-1070
Articles

7 May 2020 , Volume 96, Number 3

Adipocytes take up long chain FAs through diffusion and protein-mediated transport, whereas FA efflux is considered to occur by diffusion. To identify potential membrane proteins that are involved in regulating FA flux in adipocytes, the expression levels of 55 membrane transporters without known function were screened in subcutaneous adipose samples from obese patients before and after bariatric surgery using branched DNA methodology. Among the 33 solute carrier (SLC) transporter family members screened, the expression of 14 members showed significant changes before and after bariatric surgery. One of them, Slc43a3, increased about 2.5-fold after bariatric surgery. Further investigation demonstrated that Slc43a3 is highly expressed in murine adipose tissue and induced during adipocyte differentiation in primary preadipocytes and in OP9 cells. Knockdown of Slc43a3 with siRNA in differentiated OP9 adipocytes reduced both basal and forskolin-stimulated FA efflux, while also increasing FA uptake and lipid droplet accumulation. In contrast, overexpression of Slc43a3 decreased FA uptake in differentiated OP9 cells and resulted in decreased lipid droplet accumulation. Therefore, Slc43a3 seems to regulate FA flux in adipocytes, functioning as a positive regulator of FA efflux and as a negative regulator of FA uptake.

8 January 2020 , Volume 96, Number 1

Many of today.s most striking buildings are nontraditional freeform shapes. A new field of mathematics, discrete differential geometry, makes it possible to construct these complex shapes that begin as designers. digital creations. Since it.s impossible to fashion a large structure out of a single piece of glass or metal, the design is realized using smaller pieces that best fit the original smooth surface. Triangles would appear to be a natural choice to represent a shape, but it turns out that using quadrilaterals.which would seem to be more difficult.saves material and money and makes the structure easier to build. One of the primary goals of researchers is to create an efficient, streamlined process that integrates design and construction parameters so that early on architects can assess the feasibility of a given idea. Currently, implementing a plan involves extensive (and often expensive) interplay on computers between subdivision.breaking up the entire structure into manageable manufacturable pieces.and optimization.solving nonlinear equations in high-dimensional spaces to get as close as possible to the desired shape. Designers and engineers are seeking new mathematics to improve that process. Thus, in what might be characterized as a spiral with each field enriching the other, their needs will lead to new mathematics, which makes the shapes possible in the first place. For More Information: .Geometric computing for freeform architecture,. J. Wallner and H. Pottmann. Journal of Mathematics in Industry, Vol. 1, No. 4, 2011.