Slackliners set world record, balancing at 2,500 metres high between hot air balloons

World record set at extreme Antarctica Ice Ultra race

The problem of sin isn’t fundamentally external. It’s most visible in our actions, but our actions are merely the manifestation of a corruption that comes from within.

The doctrine of man’s depravity, of all the cardinal biblical truths should never need to be defended. The empirical evidence for man’s sinful nature is irrefutable and ubiquitous. It is the inescapable reality of life.

All false religions lie to us about man. While most of them concede that man has not reached perfection, they refuse to acknowledge the bare sinful facts of life and history. They insist on offering a system of human achievement that can please God. Only God’s Word tells us the painful yet loving truth.

When it comes to man’s fallen nature, Scripture is clear about the depth and breadth of its defilement. The apostle Paul delivers a blunt assessment of man’s sinful corruption in his epistle to the Romans.

Until recently, Margaret Natabi would never have dreamed of taking her anti-corruption fight on the streets of Uganda’s capital, Kampala. Natabi, 24, is a University student. She has first-hand experience of how corruption affects marginalized groups, especially women and girls. She was orphaned during childhood. Her mother died while giving birth to one of her […]

Half of the participants in the Taxing Times survey still find compliance with tax obligations difficult

This paper is part of a cross-country study on corporate governance in Asia. A consensus has yet to be reached about exactly what factors were behind the crisis of 1998 and how these factors interacted in bringing about the crisis.

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The U-Tapao International Airport is the core infrastructure of the EEC and its expansion project is to be implemented via Public-Private Partnership modality. Land transport network connecting the U-Tapao International Airport in the Eastern Economic Corridor (EEC) to the rest of the Pattaya City and country cannot adapt to changing needs as a result of the expansion plan of the airport due to the limitations of the existing land transport network to cope with traffic increase.

This report shares insights on economic corridor development (ECD) from the 2023 Regional Cooperation and Integration (RCI) Conference, discussing how ECD can help diversify trade, cut costs, and support regional growth.

The project will build and equip 3 climate-resilient and energy-efficient border crossing points (BCP) between the Kyrgyz Republic and Kazakhstan on the Kyrgyz side of the border and a training center for the Kyrgyz Border Service (the project EA). The project with the total loan and grant financing of $37 Million will help facilitate trade and tourism between the Kyrgyz Republic and Kazakhstan and will contribute to the sustainable economic development along the Almaty-Bishkek Economic Corridor.

Eight Australian sea lions were fitted with cameras and trackers to capture unprecedented insights into their behaviour and the marine habitats where they hunt

Forget videos by gamers or influencers. For a real online thrill, watch the world's biggest flower emerging in a former web designer's greenhouse, says Annalee Newitz

Custom-made wool caps have enabled scientists to record electroencephalograms in awake cats for the first time, which could help assess their pain levels

The Linac Coherent Light Source in California fired an X-ray pulse that lasted only a few hundred billionths of a billionth of a second but carried nearly a terawatt of power

A jiggling robot has revealed the ideal vibrating speed to free jumbled fibres

Light can be directed and steered around bends using a method similar to the way clouds scatter photons, which could lead to advances in medical imaging, cooling systems and even nuclear reactors

Earth’s iron-rich inner core may owe some of its surprising softness to the motion of atoms, suggest experiments with iron at high temperature and pressure coupled to AI simulations

As a 15-kilometre crack formed ahead of the recent eruptions, magma flowed into it at the highest rate observed anywhere in the world

The Kikai-Akahoya eruption of an underwater volcano off the coast of Japan ejected enough material to fill Lake Tahoe twice, three times as much as the eruption of Mount Tambora in 1815

Millions of tonnes of water vapour have been lingering in the atmosphere since the Hunga Tonga-Hunga Ha’apai volcano erupted in 2022– possibly contributing to global warming

A scientific drilling ship has burrowed further into Earth’s mantle than ever before, obtaining new clues about the processes that feed oceanic volcanoes and the possible origins of life

After over a year of record-high global sea temperatures, the equatorial Atlantic is cooling off more quickly than ever recorded, which could impact weather around the world

Light can be directed and steered around bends using a method similar to the way clouds scatter photons, which could lead to advances in medical imaging, cooling systems and even nuclear reactors

An annual accounting of CO2 emissions from burning fossil fuels and land use change finds no sign emissions will peak this year

Title: First Biosynthetic Corneas Implanted
Category: Health News
Created: 8/26/2010 10:54:00 AM
Last Editorial Review: 8/26/2010 10:54:57 AM

Title: Record Heat Requires Exercise Precautions
Category: Health News
Created: 8/26/2010 10:10:00 AM
Last Editorial Review: 8/27/2010 12:00:00 AM

Title: College Football Players Score More Injuries at Exam Time
Category: Health News
Created: 8/21/2015 12:00:00 AM
Last Editorial Review: 8/24/2015 12:00:00 AM

Title: Label Mix-up Spurs Recall of Accord Blood Pressure Meds
Category: Health News
Created: 8/29/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM

Title: Do More to Strengthen Your Core
Category: Health News
Created: 8/26/2019 12:00:00 AM
Last Editorial Review: 8/26/2019 12:00:00 AM

Title: Coronavirus' Weird Trip Inside Cells Might Be Its Undoing, Scientists Say
Category: Health News
Created: 8/24/2020 12:00:00 AM
Last Editorial Review: 8/24/2020 12:00:00 AM

Title: Pop Concert Held to Learn More About Coronavirus Spread
Category: Health News
Created: 8/24/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM

Title: What If Many Americans Say No to a Coronavirus Vaccine?
Category: Health News
Created: 8/25/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM

Title: Confirmed Case of Coronavirus Reinfection Reported
Category: Health News
Created: 8/25/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM

Title: FDA Approves Wider Use of Plasma as Coronavirus Treatment
Category: Health News
Created: 8/24/2020 12:00:00 AM
Last Editorial Review: 8/25/2020 12:00:00 AM

Title: More Evidence That Masks Help Shield You From Coronavirus
Category: Health News
Created: 8/26/2020 12:00:00 AM
Last Editorial Review: 8/26/2020 12:00:00 AM

Title: FDA Approves New Rapid Coronavirus Test
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/27/2020 12:00:00 AM

Title: Flu Virus Can Travel on Dust. Can Coronavirus?
Category: Health News
Created: 8/26/2020 12:00:00 AM
Last Editorial Review: 8/27/2020 12:00:00 AM

Title: Search for Coronavirus Origins at Standstill: WHO Team
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/26/2021 12:00:00 AM

Title: Record High COVID Cases and Deaths Reported in Florida
Category: Health News
Created: 8/26/2021 12:00:00 AM
Last Editorial Review: 8/26/2021 12:00:00 AM

Title: Corneal Ulcer
Category: Diseases and Conditions
Created: 7/7/2010 12:00:00 AM
Last Editorial Review: 7/29/2022 12:00:00 AM

Title: Bioengineered Pig Skin Is Turned Into Corneas, Restoring Patients' Sight
Category: Health News
Created: 8/11/2022 12:00:00 AM
Last Editorial Review: 8/12/2022 12:00:00 AM

Two decades into the era of Electronic Health Records (EHRs), the promise of streamlining clinical care, reducing burden, and improving patient outcomes has yet to be realized. A cross-sectional family physician census conducted by the American Board of Family Medicine in 2022 and 2023 included self-reported physician EHR satisfaction. Of the nearly 10,000 responding family physicians, only one-in-four (26.2%) report being very satisfied and one-in-three (33.8%) were not satisfied. These low levels of satisfaction point to the need for greater transparency in the marketplace and pressure to increase user-centric EHR design.

Introduction:

High-quality primary care can reduce avoidable emergency department visits and emergency hospitalizations. The availability of electronic medical record (EMR) data and capacities for data storage and processing have created opportunities for predictive analytics. This systematic review examines studies which predict emergency department visits, hospitalizations, and mortality using EMR data from primary care.

Introduction

Exacerbation of COPD complicated by respiratory acidaemia is the commonest indication for noninvasive ventilation (NIV). The NIV outcomes (NIVO) score offers the best estimate of survival for those ventilated. Unfortunately, two-thirds of cases of COPD are unrecognised, and patients may present without COPD having been confirmed by spirometry.

Hepatocyte nuclear factor 4 alpha antisense 1 (HNF4A-AS1) is a long noncoding RNA (lncRNA) gene physically located next to the transcription factor HNF4A gene in the human genome. Its transcription products have been reported to inhibit the progression of hepatocellular carcinoma (HCC) and negatively regulate the expression of cytochrome P450s (CYPs), including CYP1A2, 2B6, 2C9, 2C19, 2E1, and 3A4. By altering CYP expression, lncRNA HNF4A-AS1 also contributes to the susceptibility of drug-induced liver injury. Thus, HNF4A-AS1 lncRNA is a promising target for controlling HCC and modulating drug metabolism. However, HNF4A-AS1 has four annotated alternative transcripts in the human genome browsers, and it is unclear which transcripts the small interfering RNAs or small hairpin RNAs used in the previous studies are silenced and which transcripts should be used as the target. In this study, four annotated and two newly identified transcripts were confirmed. These six transcripts showed different expression levels in different liver disease conditions, including metabolic dysfunction-associated steatotic liver disease, alcohol-associated liver disease, and obesity. The expression patterns of all HNF4A-AS1 transcripts were further investigated in liver cell growth from human embryonic stem cells to matured hepatocyte-like cells, HepaRG differentiation, and exposure to rifampicin treatment. Several HNF4A-AS1 transcripts highly displayed correlations with these situations. In addition, some of the HNF4A-AS1 transcripts also showed a strong correlation with CYP3A4 during HepaRG maturation and rifampicin exposure. Our findings provide valuable insights into the specific roles of HNF4A-AS1 transcripts, paving the way for more targeted therapeutic strategies for liver diseases and drug metabolism.