“Upload” feels like a slight, funny show — until you realize that without the jokes, the story would be unwatchably bleak. The Amazon Prime Video series (created by Greg Daniels of “The Office,” “Parks & Recreation” and the upcoming “Space Force”) takes place in a near future where people can upload digital copies of themselves […]

If you want to look sophisticated and classy, all you need to do is pick up your leather outfit and flaunt it with confidence. A leather garment is something you can always rely on, be it for any event or

Bollywood actress Katrina Kaif has made numerous statements in her western outfits and there is no doubt she has left us absolutely stunned in each outfit of hers. But apart from it, she has also given us some ethnic

Almost everyone is familiar with the beautiful, large and colourful flowers of the hibiscus plant. The hibiscus flowers not only create a natural beauty in your garden, but they also have medicinal uses. You can make teas and liquid extracts from

Literally everyone has turned into cine and series buffs, thanks to the current lockdown due to the pandemic. Be it television or digital streaming platforms, companies have been successful in grabbing more eyeballs, hence earning more profit. Well, Allu Arjun's Ala

Lewis Library - ML3917.U33 K34 2018

Lewis Library - ML410.M595 C53 2018

T20 cricket is no criteria to judge a bowler or his performance, says former Pakistan captain Wasim Akram.

This shy little cotton ball seems to have found herself the perfect hiding place.

Wanderfly is excited to work with People.com to help users discover great travel recommendations in and around London!

Check out the widget now and get ready to cheer your team on at the 2012 Summer Olympics!

Check out travel recommendations at Wanderfly!

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WASHINGTON (April 28, 2020) — Today, the U.S.

NEW YORK – Because levels of contamination in groundwater are falling naturally, the U.S. Environmental Protection Agency (EPA) is proposing to amend part of its previous plan to clean up an area of the Lightman Drum Company Superfund site in Winslow Township, New Jersey.

Environmental News FOR IMMEDIATE RELEASE

Ein Missbrauchsvorwurf gegen Joe Biden stürzt die US-Demokraten ins Dilemma. Seine Kritiker sagen: Würde er an den Standards gemessen, die er selbst aufgestellt hat, müsste er seine Kandidatur zurückziehen.

Ein 25-jähriger Mann hat die Anschläge auf Geschäfte türkischstämmiger Inhaber in Waldkraiburg gestanden. Der Tatverdächtige habe sich dem IS anschließen wollen, gab die Staatsanwaltschaft bekannt.

Investigators are using additional video footage to reconstruct the February afternoon that Ahmaud Arbery was fatally shot in a quiet southern Georgia neighborhood.

Investigators are using additional video footage to reconstruct the February afternoon that Ahmaud Arbery was fatally shot in a quiet southern Georgia neighborhood.

The 26-year-old surfer was pronounced dead at the scene near Manresa State Beach, California parks officials said.

An Amaryllis Azure Butterfly, photographed on Buloke mistletoe, near Stanhope in Victoria.

A Skipper Butterfly, photographed today in my backyard in Bendigo, Victoria.

An Amaryllis Azure Butterfly, photographed today on Buloke mistletoe, near Stanhope in Victoria.

South Dakota Governor Kristi Noem sent letters to two Sioux tribes demanding they remove COVID-19 checkpoints because they interfere with traffic.

Contact between inflammatory cells and endothelial cells (ECs) is a crucial step in vascular inflammation. Recently, we demonstrated that the cell-surface level of endomucin (EMCN), a heavily O-glycosylated single-transmembrane sialomucin, interferes with the interactions between inflammatory cells and ECs. We have also shown that, in response to an inflammatory stimulus, EMCN is cleared from the cell surface by an unknown mechanism. In this study, using adenovirus-mediated overexpression of a tagged EMCN in human umbilical vein ECs, we found that treatment with tumor necrosis factor α (TNF-α) or the strong oxidant pervanadate leads to loss of cell-surface EMCN and increases the levels of the C-terminal fragment of EMCN 3- to 4-fold. Furthermore, treatment with the broad-spectrum matrix metalloproteinase inhibitor batimastat (BB94) or inhibition of ADAM metallopeptidase domain 10 (ADAM10) and ADAM17 with two small-molecule inhibitors, GW280264X and GI254023X, or with siRNA significantly reduced basal and TNFα-induced cell-surface EMCN cleavage. Release of the C-terminal fragment of EMCN by TNF-α treatment was blocked by chemical inhibition of ADAM10 alone or in combination with ADAM17. These results indicate that cell-surface EMCN undergoes constitutive cleavage and that TNF-α treatment dramatically increases this cleavage, which is mediated predominantly by ADAM10 and ADAM17. As endothelial cell-surface EMCN attenuates leukocyte–EC interactions during inflammation, we propose that EMCN is a potential therapeutic target to manage vascular inflammation.

Millie Small, the first Jamaican vocalist in popular music to make the world stop and look at Jamaica as an emerging musical powerhouse, passed away in London on May 5. She was 72 years old. Speaking to Small by telephone from her home in Shepherd’...

A study at Columbia University Mailman School of Public Health found that black subjects who were exposed to highly segregated neighborhoods in young adulthood exhibited worse performance in cognitive skills in mid-life.

Epithelial cells are held together and connected by several different types of structures that form cell-cell contacts.

Kartik Aaryan has been quite active on social media in raising awareness about the pandemic and at the same time requesting all his fans to stay indoors. Not only that but the talented star has also come out in support of the government and contributed...

God opens doors for an international team to minister in Urfa, Turkey, an ancient city with no Christian church and only a handful of believers.

Maputo, Mozambique :: Logos Hope crewmembers visit local homeless boys in a slum area and were encouraged by their willingness to give.

Transform mission conference one year, outreach team in France the following year, the sisters from Mexico are eager to share the love of Christ, realising the audience was different from what they expected.

A MDT trainee puts what she has learned into practice as she teaches German to an Egyptian immigrant in Switzerland.

A Muslim man sees God answer prayers, receives a New Testament and then searches for more.

Transform mission conference one year, outreach team in France the following year, the sisters from Mexico are eager to share the love of Christ, realising the audience was different from what they expected.

Transform mission conference one year, outreach team in France the following year, the sisters from Mexico are eager to share the love of Christ, realising the audience was different from what they expected.

Transform mission conference one year, outreach team in France the following year, the sisters from Mexico are eager to share the love of Christ, realising the audience was different from what they expected.

He was surfing off Manresa State Beach on the northern end of Monterey Bay.

There is a direct connection between the leader's actions and the students' success or failure.

Transform mission conference one year, outreach team in France the following year, the sisters from Mexico are eager to share the love of Christ, realising the audience was different from what they expected.

Transform mission conference one year, outreach team in France the following year, the sisters from Mexico are eager to share the love of Christ, realising the audience was different from what they expected.

A French surfer has survived a shark attack in Australia with only minor leg injuries by punching it twice, local media reported.

Three modern classic cruisers namely Royal Enfield Classic 350, Jawa and the Benelli Imperiale 400 present for a perfect rivalry. Here's which one of the three packs the most power!

As Land Rover gives the final update to the current generation of the Discovery Sport, before the brand new generation model arrives, we try to find out if these new changes allowed the SUV to hold on to its relevancy in the midst of its newer rivals

Most performance cars are not designed for Indian conditions, but does the GLC 43 AMG strike the perfect balance to be usable every day of the week and satisfy the enthusiast?

The eighth-generation Toyota Camry Hybrid arrived in India in January, while the numbers may seem impressive, in the midst of its like-for-like competitors we find out what it is like to drive one in the real world. 

Now we've got Indian helmet brands launching new products with one of the latest one being Mavox. We had to try out an IS:4151 standard helmet, so folks at Mavox sent us an FX22.D2P full-face helmet.

How well does the on-board creature comforts on the Ford Aspire perform? How practical and user-friendly are the storage spaces on offer? We evaluate this in the second part of our long term review of this sub-compact sedan.

The Volkswagen Vento TSI petrol facelift may not have much differentiation as far as looks are concerned, but it still delivers on the thrills and at the same time, stays frugal at the fuel pumps too.