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AML and CFT obligations for digital assets high on the US regulatory bodies' agenda

(The Paypers) Financial institutions (FIs) working in digital assets have been required by US regulatory bodies to pay attention to their anti-money laundering and...




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Report Links Disease to Herbicides - Calls for New Studies of Exposed Vietnam Veterans

Evidence exists linking three cancers and two other health problems with chemicals used in herbicides in the Vietnam War, a committee of the Institute of Medicine (IOM) has concluded.




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Carcinogens and Anticarcinogens in the Human Diet - A Comparison of Naturally Occurring and Synthetic Substances

Cancer-causing chemicals that occur naturally in foods are far more numerous in the human diet than synthetic carcinogens, yet both types are consumed at levels so low that they currently appear to pose little threat to human health, a committee of the National Research Council said in a report released today.




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Allowable Levels of Copper in Drinking Water Should Not Be Increased Until Studies Are Done

The federal government should not increase the maximum level of copper allowed in drinking water, because higher levels could lead to liver poisoning in infants and children with certain genetic disorders.




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Advances in Biotechnology Show Promise For Improving Army Readiness, Soldier Survival

Recent strides in biotechnology offer the promise of new and innovative applications -- from edible vaccines to protein-based electronics components.




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New Dietary Guidelines Issued for Cats and Dogs

One out of every four dogs and cats in the western world is now obese. Like humans, dogs and cats that are obese run a higher risk of developing diabetes, heart disease, or other health problems.




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Report Sets Dietary Intake Levels for Water, Salt, and Potassium To Maintain Health and Reduce Chronic Disease Risk

The vast majority of healthy people adequately meet their daily hydration needs by letting thirst be their guide, says the newest report on nutrient recommendations from the Institute of Medicine of the National Academies.




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Studies Suggest a Possible Link Between Military Service and ALS

A limited body of evidence suggests an association between military service and later development of amyotrophic lateral sclerosis (ALS), a rare but fatal neurodegenerative disorder, says a new report from the Institute of Medicine.




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IOM Report Sets New Dietary Intake Levels for Calcium and Vitamin D To Maintain Health and Avoid Risks Associated With Excess

Most Americans and Canadians up to age 70 need no more than 600 international units (IUs) of vitamin D per day to maintain health, and those 71 and older may need as much as 800 IUs, says a new report from the Institute of Medicine.




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New Report Finds EPA’s Controlled Human Exposure Studies of Air Pollution Are Warranted

The U.S. Environmental Protection Agency (EPA) carries out experiments in which volunteer participants agree to be intentionally exposed by inhalation to specific pollutants at restricted concentrations over short periods to obtain important information about the effects of outdoor air pollution on human health.




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New Report Recommends Methods and Guiding Principles for Developing Dietary Reference Intakes Based on Chronic Disease

A new report from the National Academies of Sciences, Engineering, and Medicine outlines how to examine whether specific levels of nutrients or other food substances (NOFSs) can ameliorate the risk of chronic disease and recommends ways to develop dietary reference intakes (DRI) based on chronic disease outcomes.




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New Report Calls for Comprehensive Redesign of Process for Updating Dietary Guidelines for Americans

Although the process used to develop the Dietary Guidelines for Americans (DGA) has become more evidence-based since its inception more than 30 years ago, it is not currently positioned to effectively adapt to changes such as food diversity and chronic disease prevalence, while also ensuring the integrity of the process, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.




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New Report One of Most Comprehensive Studies on Health Effects of E-Cigarettes - Finds That Using E-Cigarettes May Lead Youth to Start Smoking, Adults to Stop Smoking

A new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine takes a comprehensive look at evidence on the human health effects of e-cigarettes.




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NASA Should Update Policies That Protect Planets and Other Solar System Bodies During Space Exploration Missions, New Report Says

The current process for planetary protection policy development is inadequate to respond to increasingly complex solar system exploration missions, says a new report from the National Academies of Sciences, Engineering, and Medicine.




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Permanent Supportive Housing Holds Potential for Improving Health of People Experiencing Homelessness, but Further Research on Effectiveness Is Needed, Including Studies On ‘Housing Sensitive’ Health Conditions

A new report from the National Academies of Sciences, Engineering, and Medicine examines evidence on whether providing permanent supportive housing (PSH) – a combination of stable housing and supportive services -- to individuals who are experiencing homelessness improves their health.




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Sodium and Potassium Dietary Reference Intake Values Updated in New Report

A new report from the National Academies of Sciences, Engineering, and Medicine reviews current evidence and updates intake recommendations known as the Dietary Reference Intakes (DRIs) for sodium and potassium that were established in 2005.




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Frank Press, Former President of the National Academy of Sciences, Dies at Age 95

National Academy of Sciences President Emeritus Frank Press — distinguished geophysicist, science adviser to President Jimmy Carter, and National Medal of Science recipient — died on Wednesday, Jan. 29, at his home in Chapel Hill, North Carolina. He was 95.




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Determining Whether There Is a Link Between Antimalarial Drugs and Persistent Health Effects Requires More Rigorous Studies

Although the immediate side effects of antimalarial drugs are widely recognized, few studies were designed specifically to examine health problems that might occur or persist months or years after people stopped taking them.




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The Golden Oldies




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Tony Award-Winning Actor Brian Dennehy Has Died At The Age Of 81

Brian Dennehy, known for his interpretations of characters created by Eugene O'Neill and Arthur Miller, has died at the age of 81.; Credit: Mike Piscitelli /Dennehy Family

Andrew Limbong | NPR

Brian Dennehy could go from viciously intimidating on film to weak and weary on stage. The actor died yesterday of cardiac arrest. His family says his death was not related to COVID-19. He was 81 years old.

Dennehy had a vast and varied body of work. On screen he was known for his roles in First Blood, Cocoon, and Tommy Boy. In theater, he earned wide acclaim for his depiction of the beleagured Willy Loman in the 1999 Broadway revival of Arthur Miller's Death of a Salesman. That performance earned him one of his two Best Actor Tony Awards. He earned the other in 2003 for his portrayal of family patriarch James Tyrone in Eugene O'Neill's Long Days Journey into Night.

Brian Manion Dennehy was born in Bridgeport, Connecticut, on July 9, 1938, and grew up on Long Island, New York. He was tall and broad-chested and played football in high school, but was also in love with theater. As an Irish Catholic, he didn't see much of a future for himself in acting until he saw Marlon Brando in On the Waterfront. "For the first time when I saw that picture, I realized there were people in the business who looked like me, and who sounded like me. And who came from places I came from" he said in an interview with WHYY's Fresh Air in 1999. "Before that time, acting was like ballet — something I could appreciate but never consider myself a part of."

On stage, Dennehy was a revered actor, particularly in the Chicago theater scene. His two Tony-award winning performances began at the famed Goodman Theatre, where he also performed in Samuel Beckett's Krapp's Last Tape. On Broadway, his credits include Translations, Love Letters, and Inherit the Wind.

Earlier in his career, Dennehy wasn't picky about his roles — and he wasn't shy about it either. "I had kids," he said in the Fresh Air interview. "I had kids who were ready to go to college, and I knew I had the responsibility — which I did not resent — to make sure they had good educations." Dennhey said his wide range of roles on television, where he acted in everything from Dynasty to M*A*S*H to Just Shoot Me, helped him become a more efficient actor. Dennehy worked all throughout his life, most recently appearing in the television series The Blacklist, as well the upcoming independent film Driveways.

Copyright 2020 NPR. To see more, visit https://www.npr.org.

This content is from Southern California Public Radio. View the original story at SCPR.org.





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Will Antibodies After COVID-19 Illness Prevent Reinfection?

Richard Harris | NPR

Most people infected with the novel coronavirus develop antibodies in response.

But scientists don't know whether people who have been exposed to the coronavirus will be immune for life, as is usually the case for the measles, or if the disease will return again and again, like the common cold.

"This to me is one of the big unanswered questions that we have," says Jeffrey Shaman, a professor of environmental health sciences at Columbia University, "because it really says, 'What is the full exit strategy to this and how long are we going to be contending with it?' "

He's one of many scientists on a quest for answers. And the pieces are starting to fall into place.

Antibodies, which are proteins found in the blood as part of the body's immune response to infection, are a sign that people could be developing immunity. But they are by no means a guarantee they will be protected for life – or even for a year.

Shaman has been studying four other coronaviruses that cause the common cold. "They're very common and so people seem to get them quite often," Shaman says. Ninety percent of people develop antibodies to those viruses, at least in passing, but "our evidence is those antibodies are not conferring protection."

That may simply because colds are relatively mild, so the immune system doesn't mount a full-blown response, suggests Dr. Stanley Perlman, a pediatrician who studies immunology and microbiology at the University of Iowa. "That's why people get colds over and over again," he says. "It doesn't really tickle the immune response that much."

He's studied one of the most severe coronaviruses, the one that causes SARS, and he's found that the degree of immunity depended on the severity of the disease. Sicker people remained immune for much longer, in some cases many years.

For most people exposed to the novel coronavirus, "I think in the short term you're going to get some protection," Perlman says. "It's really the time of the protection that matters."

Perlman notes that for some people the symptoms of COVID-19 are no worse than a cold, while for others they are severe. "That's why it's tricky," he says, to predict the breadth of an immune response.

And it's risky to assume that experiences with other coronaviruses are directly applicable to the new one.

"Unforutunately, we cannot really generalize what kind of immunity is needed to get protection against a virus unless we really learn more about the virus," says Akiko Iwasaki, a Howard Hughes Medical Institute investigator at the Yale University School of Medicine.

An immunobiologist, she is part of a rapidly expanding effort to figure this out. She and her colleagues are already studying the immune response in more than 100 patients in the medical school hospital. She's encouraged that most people who recover from the coronavirus have developed antibodies that neutralize the coronavirus in a petri dish.

"Whether that's happening inside the body we don't really know," she cautions.

Research like hers will answer that question, eventually.

But not all antibodies are protective. Iwasaki says some can actually contribute to the disease process and make the illness worse. These antibodies can contribute to inflammation and lead the body to overreact. That overreaction can even be deadly.

"Which types of antibodies protect the host versus those that enhance the disease? We really need to figure that out," she says.

The studies at Yale will follow patients for at least a year, to find out how slowly or quickly immunity might fade. "I wish there was a shortcut," Iwasaki says, "but we may not need to wait a year to understand what type of antibodies are protective."

That's because she and other immunologists are looking for patterns in the immune response that will identify people who have long-term immunity.

Researchers long ago figured out what biological features in the blood (called biomarkers) correlate with immunity to other diseases, says Dr. Kari Nadeau, a pediatrician and immunologist at the Stanford University School of Medicine. She expects researchers will be able to do the same for the new coronavirus.

Nadeau is working on several studies, including one that seeks to recruit 1,000 people who were previously exposed to the coronavirus. One goal is to identify people who produce especially strong, protective antibody responses. She says the antibody-producing cells from those people can potentially be turned into vaccines.

Another critical question she's zeroing in on is whether people who become immune are still capable of spreading the virus.

"Because you might be immune, you might have protected yourself against the virus," she says, "but it still might be in your body and you're giving it to others."

That would have huge public health implications if it turns out people can still spread the disease after they've recovered. Studies from China and South Korea seemed to suggest this was possible, though further studies have cast doubt on that as a significant feature of the disease.

Nadeau is also trying to figure out what can be said about the antibody blood-tests that are now starting to flood the market. There are two issues with these tests. First, a positive test may be a false-positive result, so it may be necessary to run a confirmatory test to get a credible answer. Second, it's not clear that a true positive test result really indicates a person is immune, and if so for how long.

Companies would like to be able to use these tests to identify people who can return to work without fear of spreading the coronavirus.

"I see a lot of business people wanting to do the best for their employees, and for good reason," Nadeau says. "And we can never say you're fully protected until we get enough [information]. But right now we're working hard to get the numbers we need to be able to see what constitutes protection and what does not."

It could be a matter of life or death to get this right. Answers to these questions are likely to come with the accumulation of information from many different labs. Fortunately, scientists around the world are working simultaneously to find answers.

You can contact NPR Science Correspondent Richard Harris at rharris@npr.org.

Copyright 2020 NPR. To see more, visit https://www.npr.org.

This content is from Southern California Public Radio. View the original story at SCPR.org.




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New science blooms after star researchers die, study finds




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New science blooms after star researchers die, study finds




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Global groundwater pumping lowers the flow of water bodies and threatens freshwater and estuarine ecosystems

Groundwater is the earth’s largest freshwater resource and is vital for irrigation and global food production. In dry periods farmers pump groundwater to water crops, this is already happening at an unsustainable level in many places — exceeding the rate at which rain and rivers can refill the groundwater stores. This study seeks to identify where groundwater pumping is affecting stream flows and estimates where and when environmentally critical stream flows — required to maintain healthy ecosystems — can no longer be sustained.




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UT study cracks coldest case: How the most famous human ancestor died

Lucy, the most famous fossil of a human ancestor, probably died after falling from a tree, according to a study appearing in Nature led by researchers at The University of Texas at Austin.

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  • Paleontology & Archaeology

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Mediterranean diet associated with lower risk of death in cardiovascular disease patients

28 Aug 2016: The Mediterranean diet is associated with a reduced risk of death in patients with a history of cardiovascular disease, according to results from the observational Moli-sani study presented at ESC Congress 2016 today.1

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  • Health & Medicine

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Prevalence of celiac appears steady but followers of gluten-free diet increase

More people are eating gluten-free, although the prevalence of celiac disease appears to have remained stable in recent years, according to an article published online by JAMA Internal Medicine.

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  • Health & Medicine

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More than one third of soils studied in southwest England are highly degraded

An extensive field investigation discovered that 38% of soils in southwest England show signs of enhanced surface water runoff due to soil degradation. The study also revealed which types of fields and soils are linked to the most or least degradation.




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‘Ecological leftovers’: a route to a sustainable diet?

Producing and consuming food has a significant environmental impact. In the search for a sustainable diet, researchers in Sweden explored a method of food production that does not exceed the level of globally available arable land per capita, and involves raising livestock on pasture or by-products not suitable for humans (the ‘ecological leftovers’ principle). The researchers developed three diets based on this method and evaluated their environmental impact compared with current diets.




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Polar and Atlantic cod share habitat, but not diet

Despite Atlantic cod and haddock extending further into Arctic waters, a new study reveals there is little competition for food between the invaders and native polar cod. However, it is uncertain whether climate change will increase competition between the species as range expansion of the Atlantic species progresses.




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Street studies: keeping the urban environment cool

Trees and other vegetation have an important influence on urban temperatures. To explore these effects, Japanese researchers have built and studied scale models of tree-lined streets. This approach could help designers and planners create urban environments that are cooler during summer months.




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A change in diet and reduction in food waste can help achieve sustainable land use

The land use associated with food imports to Germany outweighs that of exported food, leaving the country with a 'land debt', new research suggests. However, reducing the amount of animal products in the diet and minimising food waste could enable the country to achieve a positive land balance, the researchers conclude.




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Changing the Batteries on SKYCADDIE 2.5




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All 9,000 ITC Infotech employees to get bot buddies by end of the year

A look at what’s going beyond the scenes in one of the largest software bot deployments in the world.




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Diesel cars’ climate impacts not as beneficial as believed, scientists conclude

The promotion of diesel-fuelled cars in Europe may not have had the beneficial environmental effects that were expected, research suggests. It has been assumed that they help reduce greenhouse gas (GHG) emissions from the transport sector, but studies show that their fuel efficiency is lower than previously believed, while their black carbon and nitrogen oxides emissions are higher. The consequent reduction in global warming effects from diesel cars may therefore be negligible, perhaps even negative.




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A vegetarian diet can help reduce water consumption across Europe

Different European regions have very different diets and environmental conditions, meaning their water consumption varies widely. Despite this, switching to vegetarian diets in keeping with regional variation would substantially reduce water consumption in all areas, a new study concludes. Where people choose to eat meat, adopting a healthy diet low in oils and sugar will also reduce water consumption, although to a lesser degree.




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Public subsidies for electric vehicle fleets are important for adoption

Public subsidies are important in encouraging organisations to trial and expand electric vehicle fleets, according to new research. The study, based on interviews and reports from 17 organisations, found that the opportunity to test new technology was the most important factor in deciding to trial electric vehicles. However, some smaller independent companies chose not to expand their fleet because of the expense.




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Tree breeding programme to fight ash dieback recommended by study

A recent study confirms that some European ash trees are more genetically-resistant to the devastating ash dieback disease. These individuals could therefore be selected for gene conservation and/or start a breeding programme to save the European ash.




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Reforming subsidies that harm the environment

Subsidies support economic sectors and grant advantages to consumers, but can harm the environment. A new study has tested a number of existing tools for assessing environmentally harmful subsidies (EHS), developed a comprehensive methodology for identifying and analysing EHS and highlighted opportunities for reforming them.




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The significance of embodied carbon and energy in house construction

Although most energy in homes is used for heating and hot water, significant amounts of energy are also used when a house is built. A lifecycle assessment of a low-energy, affordable timber house indicates that large energy and carbon savings can be made when alternatives to traditional methods of construction are used.




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Classifying water bodies for flood risk management

Climate change is expected to increase the intensity and occurrence of regional floods in Europe. A recent study has examined existing natural and constructed retention (or holding) basins that can be adapted to provide flood defences. As part of the study, a classification system for flood defence structures was developed to help Member States design sustainable flood risk management plans.




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Management strategies for EU water bodies should consider sustainability of ecosystem services, Italy

Considering the sustainability of the services provided by an ecosystem could help to overcome management challenges and hit water quality targets defined by the EU, says a new study. By exploring 13 of the ecosystem services (ES) provided by the Venice Lagoon, Italy, the researchers identify factors affecting sustainable and unsustainable patterns of ES provision, and suggest that confined and more open water bodies could benefit from different management strategies.




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More rigorous studies needed to evaluate impact of invasive birds

Conservation researchers have warned against acting on the findings of a previous study that argued for the eradication of several invasive birds, including the Canada goose and sacred ibis, in Europe. They suggest the results are based on anecdotal rather than scientific evidence, and that detailed feasibility studies are needed before such management decisions are made.




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Ash dieback: an overview of this conservation challenge

The common ash tree (Fraxinus excelsior) is threatened by an invasive fungal disease, which is spreading throughout Europe. Scientists have recently reviewed and presented previous research into the disease which could help us understand how to prevent the spread of the fungus and develop forest conservation strategies.




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Ash dieback in the UK: how will it affect the rest of the woodland ecosystem?

Ash dieback in the UK is likely to lead to the extinction or decline of over 50 species which are reliant on or highly associated with this tree, including mosses, lichens and beetles, a new study suggests. The researchers recommend that the ash trees are not felled but left to die naturally and in time replaced with mixtures of species such as beech and sycamore which support similar woodland species.




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Ecotoxicity studies of nanomaterials urgently needed

A new study by Swiss researchers has attempted to predict nanomaterial concentrations in the environment. However, the researchers say more data on environmental toxicity are needed before we can make accurate assessments of potential environmental risks from nanomaterials.




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What are the health impacts of fish diets high in mercury?

To test the possible health impacts of human exposure to methylmercury through fish consumption, researchers fed mice a diet containing fish at levels that corresponded to a typical Western diet for humans. The mice suffered adverse health impacts after two months of being fed this diet, including reduced body growth rates and modified gene expression patterns.




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Case studies from Greenland, Poland and the Ukraine on levels of banned flame retardants

Certain chemicals that were once used as flame retardants are now banned in the EU, but can remain in the environment. A new study adds to our limited knowledge regarding the presence of the chemicals polybrominated diphenyl ethers (PBDEs) and polybrominated biphenyls (PBBs) in humans. The study suggests levels in Polish and Ukrainian men are lower than in those living in the US and Greenland.




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Active pharmaceutical ingredients in wastewater: who are the major contributors?

Active pharmaceutical ingredients (APIs) — responsible for the biological activity of drugs — have been widely found in the environment, yet the precise sources and relative importance of emissions via wastewater are not quite clear. This study assessed emissions from three health institutions in Germany — a hospital, a psychiatric hospital, and a nursing home — and found their contribution was low compared to that from households. However, more research is needed to understand the environmental effects of neurological drugs, emissions of which were in some cases relatively high.