bi La Situación de Cambio Constante entre EE UU y México: Tendencias y Políticas de Migración, Incluyendo Menores No Acompañados By www.migrationpolicy.org Published On :: Wed, 23 Aug 2017 15:25:50 -0400 Una llamada en español que analiza las dinámicas cambiantes y las cuestiones políticas relacionadas con la migración a través de México a los Estados Unidos. Full Article
bi La Situación de Cambio Constante entre EE UU y México: Tendencias y Políticas de Migración, Incluyendo Menores No Acompañados By www.migrationpolicy.org Published On :: Fri, 01 Sep 2017 12:31:52 -0400 Durante este seminario, ponentes presentaron hallazgos de un reciente informe que utiliza datos de agencias gubernamentales mexicanas, entrevistas con funcionarios clave y relatos de la sociedad civil para examinar el marco legal para la protección de menores no acompañados y su aplicación, al igual que las brechas entre este marco y su aplicación durante los procesos de detención, interrogación y alojamiento. El presidente de MPI, Andrew Selee, también expuso cómo el cambio en la dinámica política en Estados Unidos puede afectar las cuestiones migratorias con México, así como los efectos en la relación bilateral en medio de tensiones sobre el muro fronterizo, la renegociación del acuerdo del TLCAN y una cifra significativa de repatriaciones de migrantes mexicanos. Full Article
bi Intellectual Disability in KATP Channel Neonatal Diabetes By care.diabetesjournals.org Published On :: 2020-02-20T11:55:29-08:00 OBJECTIVE Neonatal diabetes has been shown to be associated with high neuropsychiatric morbidity in a genotype-phenotype–dependent manner. However, the specific impact of different mutations on intellectual functioning is still insufficiently characterized. Specifically, only a small number of subjects with developmental delay have been comprehensively assessed, creating a knowledge gap about patients carrying the heaviest burden. RESEARCH DESIGN AND METHODS We assessed the intellectual functioning and mental health of the complete Norwegian population with KATP channel neonatal diabetes. Eight sulfonylurea-treated children (five with the p.V59M genotype [KCNJ11]) were assessed using age-matched control subjects with type 1 diabetes. The investigations included a physical and motor developmental examination, cerebral MRI, psychometrical examination, and questionnaires assessing intellectual capabilities and psychiatric morbidity. RESULTS A strong genotype-phenotype correlation was found, revealing the p.V59M genotype as highly associated with substantial intellectual disability, with no significant correlation with the time of sulfonylurea initiation. Consistent with previous studies, other genotypes were associated with minor cognitive impairment. Cerebral MRI verified normal brain anatomy in all but one child. CONCLUSIONS We here presented a comprehensive assessment of intellectual functioning in the largest cohort of p.V59M subjects to date. The level of intellectual disability revealed not only changes the interpretation of other psychological measures but downplays a strong protective effect of sulfonylurea. Within the scope of this study, we could not find evidence supporting an early treatment start to be beneficial, although a weaker effect cannot be ruled out. Full Article
bi Glucosamine Use, Inflammation, and Genetic Susceptibility, and Incidence of Type 2 Diabetes: A Prospective Study in UK Biobank By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE Glucosamine is a widely used supplement typically taken for osteoarthritis and joint pain. Emerging evidence suggests potential links of glucosamine with glucose metabolism, inflammation, and cardiometabolic risk. We prospectively analyzed the association of habitual glucosamine use with risk of type 2 diabetes (T2D) and assessed whether genetic susceptibility and inflammation status might modify the association. RESEARCH DESIGN AND METHODS This study analyzed 404,508 participants from the UK Biobank who were free of diabetes, cancer, or cardiovascular disease at baseline and completed the questionnaire on supplement use. Cox proportional hazards models were used to evaluate the association between habitual use of glucosamine and risk of incident T2D. RESULTS During a median of 8.1 years of follow-up, 7,228 incident cases of T2D were documented. Glucosamine use was associated with a significantly lower risk of T2D (hazard ratio 0.83, 95% CI 0.78–0.89) after adjustment for age, sex, BMI, race, center, Townsend deprivation index, lifestyle factors, history of disease, and other supplement use. This inverse association was more pronounced in participants with a higher blood level of baseline C-reactive protein than in those with a lower level of this inflammation marker (P-interaction = 0.02). A genetic risk score for T2D did not modify this association (P-interaction = 0.99). CONCLUSIONS Our findings indicate that glucosamine use is associated with a lower risk of incident T2D. Full Article
bi Michigan coach Jim Harbaugh proposes major changes to NFL Draft eligibility rules By www.upi.com Published On :: Thu, 07 May 2020 19:41:19 -0400 Michigan coach Jim Harbaugh is urging the NFL and NCAA to amend their rules and provide flexibility to college football players who consider making the jump to the next level. Full Article
bi Opportunities and Challenges for Biosimilars: What's on the Horizon in the Global Insulin Market? By clinical.diabetesjournals.org Published On :: 2012-10-01 Lisa S. RotensteinOct 1, 2012; 30:138-150Features Full Article
bi Clinical Outcomes in Patients With Isolated or Combined Diabetic Ketoacidosis and Hyperosmolar Hyperglycemic State: A Retrospective, Hospital-Based Cohort Study By care.diabetesjournals.org Published On :: 2020-01-20T12:00:30-08:00 OBJECTIVE Many patients with hyperglycemic crises present with combined features of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS). The implications of concomitant acidosis and hyperosmolality are not well known. We investigated hospital outcomes in patients with isolated or combined hyperglycemic crises. RESEARCH DESIGN AND METHODS We analyzed admissions data listing DKA or HHS at two academic hospitals. We determined 1) the frequency distributions of HHS, DKA, and combined DKA-HHS (DKA criteria plus elevated effective osmolality); 2) the relationship of markers of severity of illness and clinical comorbidities with 30-day all-cause mortality; and 3) the relationship of hospital complications associated with insulin therapy (hypoglycemia and hypokalemia) with mortality. RESULTS There were 1,211 patients who had a first admission with confirmed hyperglycemic crises criteria, 465 (38%) who had isolated DKA, 421 (35%) who had isolated HHS, and 325 (27%) who had combined features of DKA-HHS. After adjustment for age, sex, BMI, race, and Charlson Comorbidity Index score, subjects with combined DKA-HHS had higher in-hospital mortality compared with subjects with isolated hyperglycemic crises (adjusted odds ratio [aOR] 2.7; 95% CI 1.4, 4.9; P = 0.0019). In all groups, hypoglycemia (<40 mg/dL) during treatment was associated with a 4.8-fold increase in mortality (aOR 4.8; 95% CI 1.4, 16.8). Hypokalemia ≤3.5 mEq/L was frequent (55%). Severe hypokalemia (≤2.5 mEq/L) was associated with increased inpatient mortality (aOR 4.9; 95% CI 1.3, 18.8; P = 0.02). CONCLUSIONS Combined DKA-HHS is associated with higher mortality compared with isolated DKA or HHS. Severe hypokalemia and severe hypoglycemia are associated with higher hospital mortality in patients with hyperglycemic crises. Full Article
bi Watch: Large flock of migrating birds shows up on Florida weather radar By www.upi.com Published On :: Wed, 06 May 2020 13:36:16 -0400 A Florida TV station's weather radar detected a large mass between the state and Cuba that turned out to be something other than an unseasonable storm -- it was a flock of migrating birds. Full Article
bi Planet already seeing temps beyond human tolerability By www.upi.com Published On :: Sat, 09 May 2020 04:42:06 -0400 Researchers have predicted that if climate change goes unabated, the planet will experience intolerable heat in several decades. But a new study has found that in certain global hot spots, it's already happening. Full Article
bi Feasibility of Outpatient Fully Integrated Closed-Loop Control: First studies of wearable artificial pancreas By care.diabetesjournals.org Published On :: 2013-07-01 Boris P. KovatchevJul 1, 2013; 36:1851-1858Diabetes Care Symposium Full Article
bi Exploring the Potential of the SGLT2 Inhibitor Dapagliflozin in Type 1 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Pilot Study By care.diabetesjournals.org Published On :: 2015-03-01 Robert R. HenryMar 1, 2015; 38:412-419Evolving Tactics With Inhibition of Sodium-Glucose Cotransporters Full Article
bi Efficacy and Safety of Canagliflozin, a Sodium-Glucose Cotransporter 2 Inhibitor, as Add-on to Insulin in Patients With Type 1 Diabetes By care.diabetesjournals.org Published On :: 2015-12-01 Robert R. HenryDec 1, 2015; 38:2258-2265Special Article Collection: Insulin Full Article
bi Lower Risk of Death With SGLT2 Inhibitors in Observational Studies: Real or Bias? By care.diabetesjournals.org Published On :: 2018-01-01 Samy SuissaJan 1, 2018; 41:6-10Perspectives in Care Full Article
bi Sodium-Glucose Cotransporter 2 Inhibition and Glycemic Control in Type 1 Diabetes: Results of an 8-Week Open-Label Proof-of-Concept Trial By care.diabetesjournals.org Published On :: 2014-05-01 Bruce A. PerkinsMay 1, 2014; 37:1480-1483Novel Communications in Diabetes Full Article
bi Northrop Grumman, Raytheon partner for Next Generation Interceptor bid By www.upi.com Published On :: Mon, 04 May 2020 13:19:43 -0400 Northrop Grumman Corp. and Raytheon Missiles and Defense will partner to develop the Defense Department's next missile interceptor, they announced on Monday. Full Article
bi Gestational Diabetes Mellitus and Diet: A Systematic Review and Meta-analysis of Randomized Controlled Trials Examining the Impact of Modified Dietary Interventions on Maternal Glucose Control and Neonatal Birth Weight By care.diabetesjournals.org Published On :: 2018-07-01 Jennifer M. YamamotoJul 1, 2018; 41:1346-1361Reconsidering Pregnancy With Diabetes Full Article
bi Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study By care.diabetesjournals.org Published On :: 2016-10-01 Khalid A. JadoonOct 1, 2016; 39:1777-1786Emerging Technologies and Therapeutics Full Article
bi DPP-4 Inhibitors: Impact on glycemic control and cardiovascular risk factors By care.diabetesjournals.org Published On :: 2011-05-01 Dror DickerMay 1, 2011; 34:S276-S278Diabetes Treatments Full Article
bi SGLT2 Inhibitors and the Diabetic Kidney By care.diabetesjournals.org Published On :: 2016-08-01 Paola FiorettoAug 1, 2016; 39:S165-S171III. SGLT2 Therapy Full Article
bi Long-Acting Glucagon-Like Peptide 1 Receptor Agonists: A review of their efficacy and tolerability By care.diabetesjournals.org Published On :: 2011-05-01 Alan J. GarberMay 1, 2011; 34:S279-S284Diabetes Treatments Full Article
bi Association of Urine Haptoglobin With Risk of All-Cause and Cause-Specific Mortality in Individuals With Type 2 Diabetes: A Transethnic Collaborative Work By care.diabetesjournals.org Published On :: 2020-02-20T11:55:30-08:00 OBJECTIVE Haptoglobin is an acute-phase reactant with pleiotropic functions. We aimed to study whether urine haptoglobin may predict risk of mortality in people with type 2 diabetes. RESEARCH DESIGN AND METHODS We employed a transethnic approach with a cohort of Asian origin (Singapore) (N = 2,061) and a cohort of European origin (France) (N = 1,438) included in the study. We used survival analyses to study the association of urine haptoglobin with risk of all-cause and cause-specific mortality. RESULTS A total of 365 and 525 deaths were registered in the Singapore cohort (median follow-up 7.5 years [interquartile range 3.5–12.8]) and French SURDIAGENE cohort (median follow-up 6.8 years [interquartile range 4.3–10.5], respectively. Singapore participants with urine haptoglobin in quartiles 2 to 4 had higher risk for all-cause mortality compared with quartile 1 (unadjusted hazard ratio [HR] 1.47 [95% CI 1.02–2.11], 2.28 [1.62–3.21], and 4.64 [3.39–6.35], respectively). The association remained significant in quartile 4 after multiple adjustments (1.68 [1.15–2.45]). Similarly, participants in the French cohort with haptoglobin in quartile 4 had significantly higher hazards for all-cause mortality compared with quartile 1 (unadjusted HR 2.67 [2.09–3.42] and adjusted HR 1.49 [1.14–1.96]). In both cohorts, participants in quartile 4 had a higher risk of mortality attributable to cardiovascular disease and infection but not malignant tumor. CONCLUSIONS Urine haptoglobin predicts risk of mortality independent of traditional risk factors, suggesting that it may potentially be a novel biomarker for risk of mortality in patients with type 2 diabetes. Full Article
bi Respective Contributions of Glycemic Variability and Mean Daily Glucose as Predictors of Hypoglycemia in Type 1 Diabetes: Are They Equivalent? By care.diabetesjournals.org Published On :: 2020-03-20T11:50:34-07:00 OBJECTIVE To evaluate the respective contributions of short-term glycemic variability and mean daily glucose (MDG) concentration to the risk of hypoglycemia in type 1 diabetes. RESEARCH DESIGN AND METHODS People with type 1 diabetes (n = 100) investigated at the University Hospital of Montpellier (France) underwent continuous glucose monitoring (CGM) on two consecutive days, providing a total of 200 24-h glycemic profiles. The following parameters were computed: MDG concentration, within-day glycemic variability (coefficient of variation for glucose [%CV]), and risk of hypoglycemia (presented as the percentage of time spent below three glycemic thresholds: 3.9, 3.45, and 3.0 mmol/L). RESULTS MDG was significantly higher, and %CV significantly lower (both P < 0.001), when comparing the 24-h glycemic profiles according to whether no time or a certain duration of time was spent below the thresholds. Univariate regression analyses showed that MDG and %CV were the two explanatory variables that entered the model with the outcome variable (time spent below the thresholds). The classification and regression tree procedure indicated that the predominant predictor for hypoglycemia was %CV when the threshold was 3.0 mmol/L. In people with mean glucose ≤7.8 mmol/L, the time spent below 3.0 mmol/L was shortest (P < 0.001) when %CV was below 34%. CONCLUSIONS In type 1 diabetes, short-term glycemic variability relative to mean glucose (i.e., %CV) explains more hypoglycemia than does mean glucose alone when the glucose threshold is 3.0 mmol/L. Minimizing the risk of hypoglycemia requires a %CV below 34%. Full Article
bi As the United States Resettles Fewer Refugees, Some Countries and Religions Face Bigger Hits than Others By www.migrationpolicy.org Published On :: Mon, 23 Sep 2019 15:09:56 -0400 Even as refugee admissions have dropped sharply during the Trump administration, some countries and religions have been significantly more affected than others, as this commentary explores. In fiscal year 2019, 79 percent of refugees were Christian and 16 percent Muslim—as compared to 44 percent Christian and 46 percent Muslim in fiscal year 2016, which was the last full year of the Obama administration. Full Article
bi As COVID-19 Slows Human Mobility, Can the Global Compact for Migration Meet the Test for a Changed Era? By www.migrationpolicy.org Published On :: Mon, 27 Apr 2020 16:05:08 -0400 The coronavirus pandemic dramatically reshaped how human mobility is managed just as the Global Compact for Safe, Orderly, and Regular Migration was beginning to move from paper to implementation. As governments face pressing public-health, economic, and other concerns in responding to COVID-19, this MPI Europe commentary explores whether the first comprehensive global agreement on migration can adjust to a changed reality. Full Article
bi Invertir en el Vecindario: Cambios en los Patrones de Migración Entre México y Estados Unidos y Oportunidades para una Cooperación Sostenible By www.migrationpolicy.org Published On :: Fri, 20 Sep 2019 11:31:12 -0400 Presentación del reporte que refleja el contenido de encuentros del grupo de estudio sobre la migración México-Estados Unidos convocado por El Colegio de México y el Migration Policy Institute (MPI). Full Article
bi “Cubicle Activism”: Companies Face Growing Demands from Workers to Cut Ties with ICE and Others in Immigration Arena By www.migrationpolicy.org Published On :: Tue, 29 Oct 2019 16:24:30 -0400 From online petitions to organized walkouts, corporate America is facing increasing employee activism over its business involvement with agencies implementing the federal government's immigration policies. This "cubicle activism," seen at companies ranging from Amazon and Google to Bank of America and Wayfair, has garnered mixed success to date, forcing divestiture from private prison contractors but fewer results in other contexts, as this article explores. Full Article
bi Free ADA webinar offers education on how to receive electronic funds transfer payments By www.ada.org Published On :: Tue, 14 Jan 2020 07:29:00 -0600 Dentists who have had a dental plan payment check lost in the mail could consider a way to receive safe and secure payment through electronic funds transfer payments. Full Article
bi ADA standard on treating biofilm in waterlines available for comment By www.ada.org Published On :: Fri, 17 Jan 2020 12:35:00 -0600 The American Dental Association Standards Committee on Dental Products has approved the document for circulation and comment. Full Article
bi Dental sealant webinar to stream Feb. 6 By www.ada.org Published On :: Fri, 17 Jan 2020 13:12:00 -0600 The ADA will present a free webinar Feb. 6 on dental sealants, especially designed to help dental providers in communities that do not yet have sealant programs in place. Full Article
bi 2019 marks big year for Washington office By www.ada.org Published On :: Thu, 23 Jan 2020 11:56:00 -0600 The Association’s Washington office covered a wide range of advocacy issues in 2019 — from vaping to student loan reform to making sure dentistry was exempt from the U.S. Mexico-Tourism Act. Full Article
bi February JADA examines connection between healthy eating habits, untreated caries By www.ada.org Published On :: Mon, 27 Jan 2020 08:00:00 -0600 Greater compliance with dietary guidelines may reduce the chance of untreated caries in adults, according to a study published in the February issue of The Journal of the American Dental Association. Full Article
bi CDC to offer coronavirus guidance during webinar Jan. 31 By www.ada.org Published On :: Wed, 29 Jan 2020 16:04:00 -0600 The Centers for Disease Control and Prevention will provide interim guidance to clinicians regarding the coronavirus outbreak during a webinar at 2 p.m. EST Jan. 31. Full Article
bi PBHS adds mobile chairside patient education system to ADA TV By www.ada.org Published On :: Mon, 10 Feb 2020 09:21:00 -0600 PBHS, Inc. announced in January the launch of Consult Mode, an addition to ADA TV that enables dental providers to demonstrate 3D procedural animations, videos and tutorials chairside via tablets, iPads and other hand-held devices. Full Article
bi Free ADA webinar to help dentists with social media marketing By www.ada.org Published On :: Wed, 12 Feb 2020 14:01:00 -0600 The ADA is hosting a free webinar in March on how to effectively advertise and market services and dental practices on Facebook and Instagram. Full Article
bi ADA comments on surprise billing By www.ada.org Published On :: Thu, 13 Feb 2020 11:36:00 -0600 The American Dental Association is weighing in on two pieces of legislation aimed at streamlining billing procedures for patients. Full Article
bi Narwhal exhibit to start U.S. tour March 28 By www.ada.org Published On :: Thu, 27 Feb 2020 12:22:00 -0600 Dr. Martin Nweeia began researching narwhals in 2000. He came to the conclusion that the prevailing research available about the narwhal’s tooth — such as Charles Darwin’s belief that the narwhal’s tooth was a secondary sexual characteristic like an antler or a horn — was only part of the story. Full Article
bi FDA approves combination ibuprofen-acetaminophen drug for U.S. By www.ada.org Published On :: Mon, 02 Mar 2020 13:59:00 -0600 The Food and Drug Administration has approved the first over-the-counter ibuprofen and acetaminophen combination drug for the U.S. Full Article
bi Vaping bill passes House By www.ada.org Published On :: Mon, 02 Mar 2020 16:37:00 -0600 The U.S. House of Representatives Feb. 28 passed a comprehensive bill designed to address the youth tobacco epidemic. Full Article
bi ADA to stream dental insurance webinar in April By www.ada.org Published On :: Thu, 05 Mar 2020 13:16:00 -0600 Trying to navigate the world of dental benefits can be full of choppy seas, and the ADA is holding a free webinar in April to help dentists and their staff find a safe harbor full of information. Full Article
bi ADA lobbies Congress’ coronavirus legislative package By www.ada.org Published On :: Tue, 17 Mar 2020 15:17:00 -0500 As Congress works on legislation in response to the coronavirus disease outbreak, the ADA is working to ensure that those bills include provisions that are beneficial to dentists — particularly dental practice owners — and their patients. Full Article
bi Free ADA webinar offering answers to pressing COVID-19 questions By www.ada.org Published On :: Tue, 17 Mar 2020 17:43:00 -0500 The ADA is partnering with the Organization for Safety, Asepsis and Prevention in providing a free on-demand webinar on Friday, March 20, with content for the program based on questions the ADA has received from members looking for guidance while navigating the novel coronavirus pandemic. Full Article
bi Infection control webinar from ADA, OSAP available late March 20 By www.ada.org Published On :: Thu, 19 Mar 2020 11:20:00 -0500 On March 20, the ADA will release an on-demand webinar offering answers to frequently asked questions about infection control protocol and procedures related to COVID-19. Full Article
bi ADA begins to address coding, billing procedures during COVID-19 outbreak By www.ada.org Published On :: Thu, 19 Mar 2020 16:52:00 -0500 The ADA is releasing a guide intended to help dental offices navigate issues related to coding and billing for virtual check-ins in the midst of the COVID-19 outbreak. Full Article
bi ADA infection control webinar live By www.ada.org Published On :: Fri, 20 Mar 2020 14:59:00 -0500 The ADA posted an on-demand webinar March 20 offering answers to frequently asked questions about infection control in the midst of the COVID-19 pandemic. Full Article
bi ADA lobbies Congress on CARES Act By www.ada.org Published On :: Fri, 20 Mar 2020 16:22:00 -0500 The ADA on March 20 sent out a Legislative Issues Alert to dentists, assuring them that the Association continues to lobby on their behalf in response to the Coronavirus Aid, Relief and Economic Security Act. Full Article
bi Two March 27 webinars focus on surviving financial storm caused by pandemic By www.ada.org Published On :: Thu, 26 Mar 2020 15:52:00 -0500 The ADA is presenting two free webinars March 27, aiming to help dentists financially weather the economic downturn during the COVID-19 outbreak and illustrate how ADA advocacy has helped turn the tide. Full Article
bi ADA free webinar exploring radiographs, diagnostic imaging By www.ada.org Published On :: Thu, 09 Apr 2020 15:30:00 -0500 In a time when teledentistry is gaining more attention during the COVID-19 pandemic, the ADA will stream a free webinar in May that takes a close look at the different types of images needed for diagnosis, treatment planning and operative procedures. Full Article
bi ADA urges third-party payers to adapt coding, billing procedures to help patients recover By www.ada.org Published On :: Thu, 09 Apr 2020 16:51:00 -0500 The American Dental Association sent a letter to third-party payers urging that administrators of dental benefit plans adjust and adapt reimbursement procedures important to dentists and patients — including coverage for temporary procedures and adjusting fee schedules to account for cost of increasing infection control procedures ¬— in the midst of the “unprecedented and extraordinary circumstances dentists and their patients face” during the pandemic. Full Article
bi Webinar on Small Business Administration loans available online By www.ada.org Published On :: Fri, 10 Apr 2020 10:26:00 -0500 The ADA webinar, Small Business Administration Loans: Understanding the Options for Dentist Owners, is available online. Full Article
bi Free ADA webinar aims to help dentists plan recovery during, after pandemic By www.ada.org Published On :: Fri, 10 Apr 2020 15:00:00 -0500 The ADA is streaming a free webinar April 14 intended to help dentists jump-start their recovery process during and after the COVID-19 pandemic. Full Article