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FDA considers imports to tackle high U.S. drug prices




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Kolkata witnesses citizens protest carnival alongside Durga puja carnival

The Calcutta High Court had set aside the prohibitory orders imposed by Kolkata Police and pointed out that there was sufficient distance between the two venues where - Droher Carnival at Rani Rashmoni Avenue and Durga Puja immersion carnival at Red Road - were being organised




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Trinamool moves ECI against State BJP president, misuse of Central forces

The Trinamool Congress delegation also expressed dissatisfaction that the Election Commissioners were not available to meet the party delegation at ECI headquarters




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Solid phase peptide synthesis using side-chain unprotected arginine and histidine with Oxyma Pure/TBEC in green solvents

Green Chem., 2024, 26,10929-10939
DOI: 10.1039/D4GC03209H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Tommaso Fantoni, Andrea Orlandin, Ilaria Di Stefano, Marco Macis, Alessandra Tolomelli, Antonio Ricci, Walter Cabri, Lucia Ferrazzano
Oxyma Pure/TBEC coupling protocol in green solid phase peptide synthesis (GSPPS) eliminates protective groups on Arg and His, enhancing atom economy and reducing impurities during cleavage. The technology was extended to side-chain-free Tyr and Trp.
The content of this RSS Feed (c) The Royal Society of Chemistry




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‘I consider myself as an adventurer’: Anurag Basu

Anurag Basu says judging a reality show helped him design “Jagga Jasoos”




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Discover the inside story

The all new Ford Endeavour comes with smart interiors and commands a sturdy presence on the road




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With Pawar saheb by my side, I am 100 per cent confident of winning Baramati seat, says Yugendra as another Pawar vs Pawar battle ensues in family bastion




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Pawar saheb by my side, I’m 100 per cent confident of winning Baramati, says Yugendra




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BJP Pune city chief attacks the party for not being considered for Kasba assembly seat




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Switching of sides by sitting Cong MLA to benefit party: Kolhapur district Cong president




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Ajit Pawar meets Prakash Ambedkar at his residence in city




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‘Concentrating more on meeting voters in all 3 seats, not on holding rallies by top leaders’: Pimpri-Chinchwad NCP unit president Yogesh Behl




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World Chess Championship: India’s top GMs Pravin Thipsay, Abhijit Kunte predict a Gukesh knockout win inside 12 rounds




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'Varun Was Hanging, Upside Down...'

'Varun was so exhilarated with the intense physical action sequences.' 'Samantha is very agile.' 'I don't know how they did it. It's really hard.'




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US presidential election and Iran, Israel’s wait-and-watch strategy




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Four days before he passed away, Bibek Debroy wrote his obituary: ‘There is a world outside that exists. What if I am not there? What indeed?’




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Pratap Bhanu Mehta writes: In government and outside, Bibek Debroy remained his own person




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Inside Track: Frontrunners for BJP president




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Yogendra Yadav writes: Indians, watch the US elections like an outsider




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November 8, 1984, Forty Years Ago: Ronald Reagan re-elected as US President for the second time




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November 12, 1984, Forty Years Ago: CWC President




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The inside track

App-based taxi services have hit the road running in Technopark, save for a few halts along the way




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Over to the dark side

Big-city loneliness, modern angst and black humour garner big votes on television and Netflix, writes ANANDI MISHRA




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Serving Telugu food with a side of innovation

At Krishna’s Kitchen, the wide variety will leave you spoilt for choice




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'Varun Was Hanging, Upside Down...'

'Varun was so exhilarated with the intense physical action sequences.'





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The Brexit debate needs more tolerance on both sides | Michael White

Bad sportsmanship is not confined to either camp. Let’s have more signs of mutual respect across the divide

I’m trying to cure this summer’s unattractive impulse before it turns into a bad habit. Whenever I see someone doing something stupid or self-harming like jumping an orange light on a bike or getting tattooed from neck to ankle, I want to shout: “Brexit voter.”

It’s not nice and it’s not fair. I’m trying to stop. As Theresa May’s divided cabinet meets to decide where to go next, ministers and demoralised Whitehall officials should refrain from recrimination too. The “phoney war” lull before the negotiation storm is about to end.

Continue reading...




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GST On Non-Resident Payments

My firm takes IT projects from an online Service based Marketplace www.guru.com; where Websoft Inc (doing business as Guru.com) is an entity from Pittsburgh, USA and they charge a certain percentage (%) of the total project value as a "Project Fee" and also take a monthly fee as "Subscriptttion




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Music Review: The Dark Side Of Life: Mumbai City

<strong>EXPECTATIONS</strong> One look at the title <em>The Dark Side of Life - Mumbai City</em> and it seems more apt for a book than a feature film. Nonetheless, that is indeed the case for this film which has a mix of newcomers and experienced actors with Mahesh Bhatt being seen in a crucial part as well. While Azeem Shirazi is the biggest contributor as the lyricist, several composers come together to create half a dozen songs in the film. <img class="aligncenter size-full wp-image-925603" src="https://www.bollywoodhungama.com/wp-content/uploads/2018/11/T4.jpg" alt="" width="620" height="450" /> <strong>MUSIC</strong> The kind of sound that kick-starts <strong><em>'Aawargi'</em></strong> reminds one of the kind of music that Vikram Bhatt time and again brings in his films. Jubin Nautiyal is effective as the singer in this Sabir Khan composition which is put together by Azeem Shirazi. The trouble though is that the song sounds dated by at least a decade. Hence, even though it has a soft feel to it, the overall impact is not the kind that makes you revisit it again on loop. The song that follows next is titled <strong><em>'Tu Mujhse Nikalta Nahi'</em></strong> and has the kind of hook-line which is indeed catchy. In a bigger film with a larger setup, this Prakash Prabhakar composed and heard song may well have found good traction. Again, the song is not exceptional but still has that quintessential Bhatt touch to it which makes it stand out. Moreover, Tanveer Gazi puts together a good spin of words, especially the title. Remember <em>'Manali Trance'</em> from <em>The Shaukeens</em>? The song which follows, <strong><em>'Saanp Seedhi Wala Saanp'</em></strong>, is on the same lines and belongs to the trance genre. As a matter of fact Tripty Sinha sings this one too in the same style as that of Neha Kakkar and does manage to make an impact too. It is a new team of composer Sandeep Batraa and lyricists Azeem Shirazi and Ozil Dalal who pair up for this promotional song which is expected to bring in good entertainment quotient. However, a little impact that had been created so far is diluted to a major extent by Rashid Khan composed <strong><em>'Ae Zindagi'</em></strong> which is as sad as it gets. From the composition, writing (Nisar Akhtar) as well as the singing (Altamash Faridi Brothers) perspective, the song is really depressing and just doesn't make you root for it all. A slow moving number that is all about pathos, separation and the fact that life doesn't have much to offer to the protagonists, this one belongs to the quick-skip variety. Another newcomer, Shaan Asif Raj, is the composer for <strong><em>'Muddaton'</em></strong> which starts with the sound of guitar. Seemingly a concert number, this Azeem Shirazi written song is rendered by Amit Mishra. A soft rock number, <em>'Muddaton'</em> tries to bring in the kind of mood that was created by <em>'Sun Raha Hai'</em> [<em>Aashiqui 2</em>]. Though it does fall short, it still makes for a decent hear after all. Had it carried more punch to it, this one could well have found itself a better audience. <strong><em>'Aawargi Deewangi'</em></strong> is the song that concludes the album and its depressing notes do not really help the cause. On the same lines as <em>'Ae Zindagi'</em>, this one is written by Aslam Sani with music by Ahsan Ahmed. There is just nothing in there which arrests your attention and even though Mohammed Irfan is the singer here, you don't really find much entertainment quotient in there. <strong>OVERALL</strong> The music of <em>The Dark Side of Life - Mumbai City</em> is a mixed bag and though there is no real chartbuster out there, two-three songs at least hold your attention while at play. <strong>OUR PICK(S)</strong> <em>‘Tu Mujhse Nikalta Nahi’</em>, <em>‘Saanp Seedhi Wala Saanp’</em>, <em>‘Muddaton’</em>




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GBTA Industry Forum Series: Interview with Patrick Pacious, President & CEO, Choice Hotels

Scott Solombrino, CEO, GBTA chats with Patrick Pacious, President and CEO of Choice Hotels as part of the GBTA Industry Forum Series. Patrick shares his experience working for a hotel company where 100% hotels are franchised, the challenges facing s...




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U.S. Presidential Elections: Hillary Clinton Leading Donald Trump By Four Points Says, Poll

Democratic presidential nominee Hillary Clinton leads her Republican rival Donald Trump by 4% points, a latest national opinion poll said on Sunday, two days ahead of the crucial US general elections.




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12 Prominent Presidents of United States

As Donald Trump and Hillary Clinton slug it out for the most coveted and powerful seat, the entire world waits with abated breath to see who becomes the next US president on November 9th 2016 and gets their name inked among the pantheon.




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The Cost of Becoming the President of United States

The world is still coming to grips with the sensational victory of Donald Trump over Hillary Clinton in a closely fought election to become the 45th president of the United States.




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Future of U.S. with Donald Trump as its 45th President

Donald Trump hushed all his detractors after winning the US elections to become the 45th president of the United States. He has stunned the whole world with this victory, driving on a wave of populist rage for defeating Hillary Clinton.




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Bobby Jindal Among Probables In U.S. President-Elect Donald Trump's Cabinet

Two-term Louisiana Governor Bobby Jindal, the first ever Indian-American to be elected as a state Governor, is among the shortlisted candidates for Trump's Cabinet, according to a media report.




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Trump’s man in London a far cry from bombastic president

Republican football club owner has reputation for working behind scenes




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Ever Considered Using Natural Hair Products? Here’s Why You Should Make The Big Switch

Some trends are worth the hype and organic hair products is one such trend. Switching to natural and organic products seems like a gamble that we are not too crazy about. Don't you think that it is high time that you




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Chiranjeevi & Sridevi’s Blockbuster Jagadeka Veerudu Athiloka Sundari To Get A Sequel; Deets Inside

K Raghavendra Rao's cult-classic Jagadeka Veerudu Athiloka Sundari starring Chiranjeevi and Sridevi, is all set to complete 30 years on May 9. On the occasion, Vyjayanthi Movies released a set of videos of Nani explaining the story behind the making of




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Viraataparvam First Look Out: Sai Pallavi Looks Intense As She Waits Beside A Memorial In The Forest

Sai Pallavi's first look poster from Viraataparvam is finally out on the occasion of her birthday. The director of the thriller movie, Venu Udugula took to his social media handle to unveil the intriguing first look poster of the actress. {image-exi59ufwoaa4r2s-1589007113.jpg




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'Come up with another option': Pat Cummins on banning saliva and sweat to shine one side of the ball

Australia fast bowler Pat Cummins need an alternative option if using spit and sweat, which is used to help shine the ball is banned in the wake of the COVID-19 pandemic.




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Stock query: HDFC Bank in a short-term sideways trend

To alter the medium-term downtrend, the stock needs to decisively rally above ₹1,100




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India-China face-off in north Sikkim, troops from both sides reportedly injured

News reports suggest that a total of 150 soldiers were involved in the face-off that allegedly took place a few days back.





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My Side of the Mountain

This has never happened to me before: I enjoyed the sequel more than the original! Be assured, though, My Side of the Mountain

is very good. Young Sam Gribley goes off to live in the wilderness quite comfortably in a huge hollow tree. He trains a young falcon he named Frightful:

"Every day I worked to train Frightful. It was a long process, I would put her on her stump with a long leash and step back a few feet with some meat in my hand. Then I would whistle. The whistle was supposed eventually to mean food to her. So I would whistle, show her the meat, and after many false flaps she would finally fly to my hand. I would pet her and feed her. She could fly fairly well, so now I made sure that she never ate unless he flew to my fist.

"One day at breakfast I whistled for Frightful. I had no food, she wasn't even hungry, but she came to me anyway. I was thrilled. She had learned a whistle meant 'come.'

"I looked into her steely eyes that morning and thought I saw a gentle recognition. She puffed up her feathers as she sat on my hand. I call this a 'feather word.' It means she is content."

I also enjoyed this, from near the end of the book: "I returned to my patch on the mountain, talking to myself all the way. I talk to myself a lot, but everyone does. The human being, even in the midst of people, spends nine-tenths of his time alone with the private voices of his own head. Living alone on a mountain is not much different, except that your speaking voice gets rusty, I talked inside my head all the way home, thinking up schemes, holding conversations with Bando and Dad and Matt Spell...
"I cooked supper, and then sat down by my little fire and called a forum. It is very sociable inside my head, and I have perfected the art of getting a lot of people arguing together in silence or in a forum, as I prefer to call it. I can get four people all talking at once, and a fifth can be present, but generally I can't get him to talk. Usually these forums discuss such things as a storm and whether or not it is coming, how to make a spring suit, and how to enlarge my house without destroying the life in the tree. Tonight, however, they discussed what to do about Matt Spell. Dad kept telling me to go right down to the city and make sure he published nothing, not even a made-up story. Bando said, no, it's all right, he still doesn't know where you live, and then Matt walked into the conversation and said that he wanted to spend his spring vacation with me, and that he promised not to do anything untoward. Matt kept using 'untoward' - I don't know where he got that expression, but he liked it and kept using it - that's how I knew Matt was speaking; everything was 'untoward.'"

What I liked there was that it seemed that author Jean Craighead George described how her stories got generated. Characters in her head interacted, and she transcribed what took place onto paper. I could be wrong, but maybe.

The sequel that I liked even more is called On the Far Side of the Mountain. There's a third book, Frightful's Mountain, but I have not read it yet. It's here at my desk, so it won't be long.




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President Eisgruber issues statement on federal immigration executive order

Princeton President Christopher L. Eisgruber issued a statement to the University community Sunday, Jan. 29, 2017, on the federal immigration executive order.




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Eisgruber, other university presidents ask President Trump to 'rectify or rescind' immigration order

Princeton President Christopher L. Eisgruber and 47 other American college and university presidents today sent a letter to President Trump urging him to "rectify or rescind the recent executive order closing our country's borders to immigrants and others from seven majority-Muslim countries and to refugees from throughout the world." "If left in place," the letters says, "the order threatens both American higher education and the defining principles of our country."




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Police investigate death on Indianapolis' near northeast side

Indianapolis Metropolitan Police Department are on the scene in the area of East 32nd Street and Baltimore Avenue.

       




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Police investigate death on Indianapolis' near northeast side

Indianapolis Metropolitan Police Department are on the scene in the area of East 32nd Street and Baltimore Avenue.

       




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Insider: Michael Pittman wanted the Colts and they couldn't pass on him

The road to Indianapolis: Why Colts fell in love with Michael Pittman Jr.

       




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Insider: Michael Pittman wanted the Colts and they couldn't pass on him

The road to Indianapolis: Why Colts fell in love with Michael Pittman Jr.