Earlier in the service I read from the first chapter of Romans what is really a very, very shocking portion of Scripture just to remind you that Romans cha

Dakar, Senagal — The CEO and two executives of Australian gold mine Resolute in Mali have been arrested while in Bamako to discuss ongoing disputes with authorities, the company confirmed Sunday. CEO Terence Holohan and his two colleagues "were in Bamako to discuss with mining and tax authorities the company's business practices in Mali generally and to make progress on ongoing claims against Resolute, which continues to claim they are unfounded," Resolute said in a statement posted on its website. "Unexpectedly, the three employees were arrested after the end of these meetings on Friday," she reported. The three executives were taken the same day to the unit specializing in the fight against corruption and economic and financial delinquency — and were placed in police custody in a case of alleged forgery and damage to public property, AFP learned Saturday from a judicial and industrial source. Four employees of the Canadian company Barrick Gold, also in dispute with the Malian authorities, were detained for several days at the end of September, then released. Foreign mining companies are subject to increased pressure from the junta that came to power by force in 2020 and pays particular attention to the juicy revenues of the mining industry. "Resolute is working to reach an agreement with the Malian government that secures the long-term future of the Syama gold mine; at the same time its top priority remains the safety and well-being of its employees," the company said. The executives benefit from the support of the embassies and consulates of the United Kingdom and other countries present in Mali, she said. Resolute holds 80% of the shares in the subsidiary that owns the Syama mine, with the remaining 20% in the hands of the Malian state, according to the company's website. The Malian authorities have made the fight against corruption and the restoration of national sovereignty over natural resources their mantras. Mali, one of the poorest countries in the world, faces jihadis and a multidimensional crisis, and is also one of the leading gold producers in Africa. Gold contributes to a quarter of the national budget and three quarters of export revenues. The increased pressure on foreign companies coincided with the junta's strategic pivot toward Russia.

U.S. President-elect Donald Trump has left little question about the sort of economic policies he will pursue when he is sworn in for a second term as president in January. The once-and-future president has promised to extend existing tax cuts and implement new ones; to pursue a deregulation agenda, particularly when it comes to energy production; to reinstate a strong protectionist trade policy, including substantial tariffs on imports; and to undertake a "mass deportation" program that would remove a large number of the millions of undocumented immigrants currently residing in the United States. While there may be little doubt about the kind of policies Trump will implement, the degree to which he will pursue them is an open question. "The problem that all economists are dealing with is they don't know how much of what Trump said on the campaign trail to take seriously," Steven B. Kamin, a senior fellow at the conservative-leaning American Enterprise Institute, told VOA. "They don't know if he's going to do a lot of these things, or if he is, how far he'll take it." When it comes to tariffs, Trump has promised across-the-board 10%-20% levies on all imports, and charges of up to 60% on goods coming from China, which experts warn would be economically ruinous. His rhetoric about fossil fuel extraction suggests he will drive up oil and gas production, even though the U.S. is currently producing more energy than it ever has. On immigration, he and his advisers have vacillated between suggesting that all undocumented people will be forcibly removed and describing a much more targeted operation. Tax policy One thing that appears certain is that Trump will work with Congress — which seems likely to be fully controlled by the Republican Party — to extend the tax cuts that became law as part of the Tax Cuts and Jobs Act, which he signed into law in 2017. Those tax cuts reduced the income taxes paid by many American workers and reduced taxable income by increasing the standard deduction. They also sharply cut the top business income tax bracket from 39% to 21%. Those provisions are all scheduled to expire over the next several years, some as soon as 2025, and Trump has proposed making them permanent. Trump has also floated the idea of other tax cuts, including further reducing the business income tax to a maximum of 15%, and making income from overtime wages, tips and Social Security payments nontaxable, all of which would reduce government revenues. Kamin said the stimulative impact of Trump's proposed additional tax changes would likely not be great, but the impact on the country's debt might be, because they will virtually guarantee additional government borrowing to finance deficit spending. "The real concern for folks that are concerned about the fiscal balance — and I'm one of them — is that by cementing in place large fiscal deficits as far as the eye can see, even in environments of strong economic activity when we should be running surpluses, that leads to increases in the debt," he said. "That, eventually, should lead to crowding out of private investment, rising interest rates, and more worries about the government's sustainability position," Kamin added. "But when the debt will reach a level that will be worrisome in that respect, nobody knows." Cost-cutting In theory, some of the deficit spending made necessary by large tax cuts could be offset by a reduction in government spending, something Trump has also floated on the campaign trail. In particular, the president-elect has proposed creating a Department of Government Efficiency, to be headed by Elon Musk, the billionaire founder of the electric car company Tesla and the rocket builder SpaceX, and the owner of X, the social network formerly known as Twitter. For his part, Musk has mused that it should be possible to slash federal spending by as much as $2 trillion per year, or about 30%. Reductions of that magnitude would require deep cuts to a vast array of programs, including elements of the social safety net such as Social Security and federal health programs like Medicaid. However, it is unclear how Trump would persuade even a Republican Congress to enact such a wide-ranging reduction in government services. Immigration policy If Trump follows through on a policy of mass deportation of undocumented immigrants, it is virtually certain to have a negative impact on economic sectors where they are present as laborers in significant concentrations, especially agriculture and construction, said Marcus Noland, executive vice president and director of studies at the Peterson Institute for International Economics. "If you take lots of people out of the labor force, you reduce the amount of output, because there's less labor available, and you raise prices," Noland told VOA. "These people are not distributed evenly across the United States economy," he said. "They're concentrated in agriculture and construction, so you would disrupt those sectors the most, especially if you combine it with tariffs." Trade policy Trump's tariff proposals, especially if he follows through with his maximalist proposals from the campaign trail, could be significantly damaging. While theoretically meant to stimulate American manufacturing, Noland warned that they could have the opposite effect. "Some modeling that I worked on suggest that those tariff policies, instead of reviving the industrial sector, will actually reduce industrial activity in the United States," he warned. Blanket tariffs on imports, and especially high levies on Chinese goods, would create severe challenges for U.S. manufacturers. "The reason is that you would increase the price of industrial inputs, and so, the United States would become a high-cost place to produce," he said. "Investment would fall — and investment is intensive in industrial materials — so, ironically, it has the opposite effect of what its proponents say."

… Seek targeted relief measures to save media, nation’s economy The Nigerian Guild of Editors (NGE), arising from the three-day All Nigeria Editors Conference (ANEC) in Yenagoa, the Bayelsa State Capital, has called on the federal government to urgently mitigate the negative impact of fuel subsidy removal and the exchange rate volatility on the economy. […]

The post Ease impact of fuel subsidy removal, exchange rate volatility, editors urge FG first appeared on Business Hallmark.

On June 25, 2018 I woke up to yet another social media trend – a news story with the bold and quite salacious headline “How Safe Are Customer Deposits At FCMB?” had taken over the digital airwaves. Between the shares and likes and comments, a storm in a cup had brewed to great proportions in […]

The Worrisome Trend of Sensational Social Media “Journalism” and the Impact On Legitimate Business Concerns: Recent Travails of FCMB, GTBank and First Bank

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

La enseñanza bíblica en profundidad de John MacArthur lleva la verdad transformadora de la Palabra de Dios a millones de personas cada día.

JOHANNESBURG — South Africa's four main political parties began the final weekend of campaigning Saturday before a possibly pivotal election that could bring the country's most important change in three decades. Supporters of the long-governing African National Congress, which has been in the government ever since the end of white minority rule in 1994, gathered at a soccer stadium in Johannesburg to hear party leader and South African President Cyril Ramaphosa speak. The ANC is under unprecedented pressure to keep hold of its parliamentary majority in Africa's most advanced country. Having seen its popularity steadily decline over the last two decades, Wednesday's vote could be a landmark moment when the party once led by Nelson Mandela drops below 50% of the vote for the first time. Several polls have the ANC's support at less than 50%, raising the possibility that it will have to form a national coalition. That would also be a first for South Africa's young democracy, which was only established 30 years ago with the first all-race vote that officially ended the apartheid system of racial segregation. As thousands of supporters in the ANC's black, green and gold colors attended its last major rally before the election, Ramaphosa recognized some of the grievances that have contributed to his party losing support, which include high levels of poverty and unemployment that mainly affect the country's Black majority. “We have a plan to get more South Africans to work," Ramaphosa said. “Throughout this campaign, in the homes of our people, in the workplaces, in the streets of our townships and villages, so many of our people told us of their struggles to find work and provide for their families.” The main opposition Democratic Alliance party had a rally in Cape Town, South Africa's second-biggest city and its stronghold. Party leader John Steenhuisen made a speech while supporters in the DA's blue colors held up blue umbrellas. “Democrats, friends, are you ready for change?” Steenhuisen said. The crowd shouted back “Yes!” "Are you ready to rescue South Africa?" Steenhuisen added. While the ANC's support has shrunk in three successive national elections and appears set to continue dropping, no party has emerged to overtake it — or even challenge it — and it is still widely expected to be the largest party by some way in this election. But losing its majority would be the clearest rejection yet of the famous party that led the anti-apartheid movement and is credited with leading South Africans to freedom. Some ANC supporters at the rally in Johannesburg also expressed their frustration with progress, as South Africa battles poverty, desperately high unemployment, some of the worst levels of inequality in the world, and other problems with corruption, violent crime and the failure of basic government services in some places. “We want to see job opportunities coming and basically general change in every aspect,” ANC supporter Ntombizonke Biyela said. “Since 1994 we have been waiting for ANC, it has been long. We have been voting and voting but we see very little progress as the people, only a special few seem to benefit.” While conceding to some failures, the ANC has maintained that South Africa is a better place than it was during apartheid, when a set of race-based laws oppressed the country's Black majority in favor of a small white minority. The ANC was also widely credited with success in expanding social support and housing and other services for millions of poor South Africans in the decade after apartheid, even if critics say it has lost its way recently. "There are many problems in South Africa, but nobody can deny the changes that have happened since 1994, and that was because of the ANC,” said 42-year-old Eric Phoolo, another supporter of the ruling party. “These other parties don’t have a track record of bringing change to the country." As some voters have turned away from the ANC, it has led to a slow fracturing of South African politics. They have changed allegiances to an array of different opposition parties, some of them new. South Africa has dozens of parties registered to contest next week's election. South Africans vote for parties and not directly for their president in national elections. Parties then get seats in Parliament according to their share of the vote and the lawmakers elect the president — which is why the ANC losing its majority would be so critical to the 71-year-old Ramaphosa's hope of being reelected for a second and final five-year term. If the ANC goes below 50, it would likely need a coalition or agreement with other parties to have the votes in Parliament to keep Ramaphosa, once a protege of Mandela, as president. The far-left Economic Freedom Fighters had their last big pre-election gathering in the northern city of Polokwane, the hometown of fiery leader Julius Malema. The new MK Party of former South African President and former ANC leader Jacob Zuma was also campaigning in a township just outside the east coast city of Durban, although Zuma didn't attend the event. The 82-year-old Zuma rocked South African politics when he announced late last year he was turning his back on the ANC and joining MK, while fiercely criticizing the ANC under Ramaphosa. Zuma has been disqualified from standing as a candidate for Parliament in the election because of a previous criminal conviction.

Israel showcases climate tech at COP29 but misses deeper environmental focus.

Messianic community leaders declared Donald Trump a "trumpet of God."

[Capital FM] Nairobi -- The Politics surrounding the control of the Sh10.5 billion Road Maintenance Levy Fund between MPs and Governors has continued to stall talks to iron out the stalemate over the equitable revenue share to the devolved units.

In the coming decades, the Asia-Pacific region faces a series of challenges that threaten to exacerbate poverty. Among these, climate change, demographic shifts, particularly population ageing and the rise of digital technologies stand out as three interconnected global megatrends. A recent technical paper supporting the Social Outlook for Asia and the Pacific 2024 explores various […]

MANILA, Philippines — The excess campaign funds of then-president Rodrigo Duterte were used for the reward system of police officers during his administration’s brutal war on drugs.  Duterte himself admitted this to Santa Rosa City Rep. Dan Fernandez during the House of Representatives quad committee during its 11th probe on his controversial anti-drug campaign.  “I still remember that you mentioned na yung pera galing sa donation ng inyong campaign funds will be utilized for the reward system, that’s private money,” Fernandez said.  (I still remember you mentioned that the money from the donation for your campaign funds would be utilized […]...

Keep on reading: Excess campaign funds used for drug war reward system, Duterte admits

On November 6, the World Health Organization (WHO) announced that the second round of polio vaccinations in the Gaza Strip has been completed. A total of 556,744 children under ten years of age received the mOPV2 vaccine along with a dose of vitamin A to ensure immunization. However, due to rampant hostilities from the Israeli […]

On the 7th of November 2024, the Gauteng MEC for Finance and Economic Development, Lebogang Maile, delivered a keynote address at Bolt South Africa's Global Safety Campaign launch in Johannesburg. The campaign is aimed at improving safety in the e-hailing industry

Scientists warn of vastly higher impacts on billions of people’s livelihood and cost to the global economy by the accelerating losses in the world’s snow and ice regions, aka the cryosphere. Over 50 leading cryosphere scientists released an annual report on the status of the world’s ice stores on Tuesday (November 12) at the UN […]

Construction company Aktor (formerly Intrakat) is now seeking over €35 million in damages through the courts after the public works department terminated the contract with regarding the Paphos-Polis road project, according to its CEO Alexandros Exarchou, who spoke at an online press conference. “We are compelled to pursue our legal rights in Cyprus and, if […]

The Paphos-Polis highway is the fourth public project this government has terminated because of major disputes with the contractor. Last year it pulled the plug on the waste treatment plant in Pentakomo, while earlier this year it ended the contract for the Larnaca port and marina with Kition Ocean Holdings followed by the termination of […]

Uncovering crucial gaps in climate change data systems reveals how these deficiencies hamper our understanding of climate impacts on vulnerable populations in developing Asia. How can we empower national statistical systems in collecting and analyzing data they need to effectively tackle climate change?

Decision makers need to analyze, exchange, and disseminate statistical information effectively in today’s data-driven world. See how Statistical Data and Metadata eXchange (SDMX) standards are helping create robust data links across the globe.

Developing Asia’s outlook remains upbeat, with falling inflation and solid growth driven by strong domestic demand and exports. But risks remain, including geopolitical tensions and rising protectionism. How can the region remain resilient?

This infographic examines how extreme heat disproportionately impacts women in Asia and the Pacific, presenting data on health and economic vulnerabilities shaped by intersecting factors like age, hormonal influences, caregiving roles, and limited cooling access.

The Federal Reserve’s monetary policy has become increasingly data-dependent, with inflation and employment figures driving the nascent easing cycle. What does this mean for Asia’s financial markets?

South Asia study of foreign direct investments impact in India, Pakistan, Bangladesh, Sri Lanka and Nepal on economic growth, domestic investment, and export; special emphasis on the role of infrastructure.

This paper analyses economic and social indicators across provinces in the People's Republic of China.

Colossal, a US firm that is aiming to revive lost species such as the woolly mammoth, says it now has a near-complete genome of the extinct thylacine

There are many scary claims about excess time on digital devices for children and teenagers. Here’s a guide to the real risks - and what to do about them

Most ingredients touted as the key to better health fail to live up to the hype but fibre bucks this trend, with benefits for the whole body, not just the gut

Even though the strange behaviour we observe in the quantum realm isn’t part of our daily lives, simulations suggest it is likely our reality could be one of the many worlds in a quantum multiverse

The Chicxulub impact 66 million years ago filled the sky with fine silicate dust, which blocked out sunlight and lingered for 15 years

The Luna structure, a 1.8-kilometre-wide depression in north-west India, may have been caused by the largest meteorite to strike Earth in the past 50,000 years

Most ingredients touted as the key to better health fail to live up to the hype but fibre bucks this trend, with benefits for the whole body, not just the gut

The infinite monkey theorem states that illiterate primates could write great literature with enough time, but the amount of time needed is much longer than the lifespan of the universe

Title: Electronic Cigarettes Have Slight Impact on Heart: Study
Category: Health News
Created: 8/27/2012 2:05:00 PM
Last Editorial Review: 8/28/2012 12:00:00 AM

Title: Age Can Impair a Man's Odds for Fatherhood: Study
Category: Health News
Created: 8/23/2021 12:00:00 AM
Last Editorial Review: 8/23/2021 12:00:00 AM

Title: People Underestimate Impact of Random Acts of Kindness
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/25/2022 12:00:00 AM

Background

Immature lung development and respiratory morbidity place preterm-born children at high risk of long-term pulmonary sequelae. This systematic review and meta-analysis aims to quantify lung function in preterm-born children and identify risk factors for a compromised lung function.

High-throughput sequencing (HTS) technologies have been instrumental in investigating biological questions at the bulk and single-cell levels. Comparative analysis of two HTS data sets often relies on testing the statistical significance for the difference of two negative binomial distributions (DOTNB). Although negative binomial distributions are well studied, the theoretical results for DOTNB remain largely unexplored. Here, we derive basic analytical results for DOTNB and examine its asymptotic properties. As a state-of-the-art application of DOTNB, we introduce DEGage, a computational method for detecting differentially expressed genes (DEGs) in scRNA-seq data. DEGage calculates the mean of the sample-wise differences of gene expression levels as the test statistic and determines significant differential expression by computing the P-value with DOTNB. Extensive validation using simulated and real scRNA-seq data sets demonstrates that DEGage outperforms five popular DEG analysis tools: DEGseq2, DEsingle, edgeR, Monocle3, and scDD. DEGage is robust against high dropout levels and exhibits superior sensitivity when applied to balanced and imbalanced data sets, even with small sample sizes. We utilize DEGage to analyze prostate cancer scRNA-seq data sets and identify marker genes for 17 cell types. Furthermore, we apply DEGage to scRNA-seq data sets of mouse neurons with and without fear memory and reveal eight potential memory-related genes overlooked in previous analyses. The theoretical results and supporting software for DOTNB can be widely applied to comparative analyses of dispersed count data in HTS and broad research questions.

The human major histocompatibility complex (MHC) is a ~4 Mb genomic segment on Chromosome 6 that plays a pivotal role in the immune response. Despite its importance in various traits and diseases, its complex nature makes it challenging to accurately characterize on a routine basis. We present a novel approach allowing targeted sequencing and de novo haplotypic assembly of the MHC region in heterozygous samples, using long-read sequencing technologies. Our approach is validated using two reference samples, two family trios, and an African-American sample. We achieved excellent coverage (96.6%–99.9% with at least 30x depth) and high accuracy (99.89%–99.99%) for the different haplotypes. This methodology offers a reliable and cost-effective method for sequencing and fully characterizing the MHC without the need for whole-genome sequencing, facilitating broader studies on this important genomic segment and having significant implications in immunology, genetics, and medicine.

Background:

The COVID-19 pandemic social distancing requirements encouraged patients to avoid public spaces including in-office health care visits. Ambulatory-care-sensitive conditions (ACSCs) represent conditions that can be managed with quality primary care and when access is limited, these conditions can lead to avoidable emergency department (ED) visits.

Without compromising accuracy, point of care testing (POCT) provides immediate results at the time of in person patient consultation. The purpose of this study was to evaluate time until therapeutic intervention with POCT HbA1c versus venipuncture, where venipuncture was considered standard of care.

The primary outcome was time (hours) to implementation of a therapeutic intervention based on POCT HbA1c result, as compared with most recent venipuncture HbA1c before the study and its associated therapeutic intervention. A total of 94 POCT HbA1c tests were included in the primary analysis.

For the POCT HbA1c, the mean time to therapeutic intervention was 1.6 ± 3.14 hours. For the previous venipuncture HbA1c, the mean time to therapeutic intervention was 1376.66 ± 3356.6 hours (P < .001). Overall, this trial showed that POCT HbA1c results in a significantly faster time to therapeutic intervention than venipuncture in a primary care clinic that serves a rural population.