utility

German Utility's Race for Renewables Seen as Too Little, Too Late

RWE AG, the German utility whose coal-fired plants make it Europe’s largest carbon emitter, officially started the company’s largest renewables project on Thursday: a wind farm in Liverpool Bay off Britain’s coast.




utility

MCP2221 Utility (v1.0.2)

MCP2221 Utility (v1.0.2)




utility

First Utility-Scale Energy Storage Project

Approved project 53249-001 in Mongolia.




utility

Diagnostic Utility and Impact on Clinical Decision Making of Focused Assessment With Sonography for HIV-Associated Tuberculosis in Malawi: A Prospective Cohort Study

ABSTRACTBackground:The focused assessment with sonography for HIV-associated tuberculosis (TB) (FASH) ultrasound protocol has been increasingly used to help clinicians diagnose TB. We sought to quantify the diagnostic utility of FASH for TB among individuals with HIV in Malawi.Methods:Between March 2016 and August 2017, 210 adults with HIV who had 2 or more signs and symptoms that were concerning for TB (fever, cough, night sweats, weight loss) were enrolled from a public HIV clinic in Lilongwe, Malawi. The treating clinicians conducted a history, physical exam, FASH protocol, and additional TB evaluation (laboratory diagnostics and chest radiography) on all participants. The clinician made a final treatment decision based on all available information. At the 6-month follow-up visit, we categorized participants based on clinical outcomes and diagnostic tests as having probable/confirmed TB or unlikely TB; association of FASH with probable/confirmed TB was calculated using Fisher's exact tests. The impact of FASH on empiric TB treatment was determined by asking the clinicians prospectively about whether they would start treatment at 2 time points in the baseline visit: (1) after the initial history and physical exam; and (2) after history, physical exam, and FASH protocol.Results:A total of 181 participants underwent final analysis, of whom 56 were categorized as probable/confirmed TB and 125 were categorized as unlikely TB. The FASH protocol was positive in 71% (40/56) of participants with probable/confirmed TB compared to 24% (30/125) of participants with unlikely TB (odds ratio=7.9, 95% confidence interval=3.9,16.1; P<.001). Among those classified as confirmed/probable TB, FASH increased the likelihood of empiric TB treatment before obtaining any other diagnostic studies from 9% (5/56) to 46% (26/56) at the point-of-care. For those classified as unlikely TB, FASH increased the likelihood of empiric treatment from 2% to 4%.Conclusion:In the setting of HIV coinfection in Malawi, FASH can be a helpful tool that augments the clinician's ability to make a timely diagnosis of TB.




utility

Adenosine Signaling Is Prognostic for Cancer Outcome and Has Predictive Utility for Immunotherapeutic Response

Purpose:

There are several agents in early clinical trials targeting components of the adenosine pathway including A2AR and CD73. The identification of cancers with a significant adenosine drive is critical to understand the potential for these molecules. However, it is challenging to measure tumor adenosine levels at scale, thus novel, clinically tractable biomarkers are needed.

Experimental Design:

We generated a gene expression signature for the adenosine signaling using regulatory networks derived from the literature and validated this in patients. We applied the signature to large cohorts of disease from The Cancer Genome Atlas (TCGA) and cohorts of immune checkpoint inhibitor–treated patients.

Results:

The signature captures baseline adenosine levels in vivo (r2 = 0.92, P = 0.018), is reduced after small-molecule inhibition of A2AR in mice (r2 = –0.62, P = 0.001) and humans (reduction in 5 of 7 patients, 70%), and is abrogated after A2AR knockout. Analysis of TCGA confirms a negative association between adenosine and overall survival (OS, HR = 0.6, P < 2.2e–16) as well as progression-free survival (PFS, HR = 0.77, P = 0.0000006). Further, adenosine signaling is associated with reduced OS (HR = 0.47, P < 2.2e–16) and PFS (HR = 0.65, P = 0.0000002) in CD8+ T-cell–infiltrated tumors. Mutation of TGFβ superfamily members is associated with enhanced adenosine signaling and worse OS (HR = 0.43, P < 2.2e–16). Finally, adenosine signaling is associated with reduced efficacy of anti-PD1 therapy in published cohorts (HR = 0.29, P = 0.00012).

Conclusions:

These data support the adenosine pathway as a mediator of a successful antitumor immune response, demonstrate the prognostic potential of the signature for immunotherapy, and inform patient selection strategies for adenosine pathway modulators currently in development.




utility

Lazarus: It's time to regulate internet service like any other utility

Telecom companies will do everything possible to protect shareholder value. That means offsetting losses in TV subscribers by increasing revenue from internet-only customers.




utility

Former General Manager of Texas Business Arrested for Role in Alleged Scheme to Bribe Officials at Mexican State-Owned Electrical Utility

The former general manager of a Sugar Land, Texas-based business was arrested on Nov. 18, 2009, for his alleged role in a conspiracy to bribe Mexican government officials to secure contracts with the Comisión Federal de Electridad (CFE), a Mexican state-owned utility company.



  • OPA Press Releases

utility

Ohio Utility to Settle Clean Air Act Violations

American Municipal Power (AMP), an Ohio non-profit utility, will permanently retire its Richard H. Gorsuch Station coal-fired power plant near Marietta under a settlement to resolve violations of the Clean Air Act.



  • OPA Press Releases

utility

Two Intermediaries Indicted for Their Alleged Participation in Scheme To Bribe Officials at State-owned Electrical Utility in Mexico

Two intermediaries were indicted for their alleged roles in a conspiracy to pay and launder bribes to Mexican government officials at the Comisión Federal de Electricidad (CFE), a state-owned utility company, announced Assistant Attorney General Lanny A. Breuer of the Criminal Division; U.S. Attorney André Birotte for the Central District of California; Steven M. Martinez, Special Agent-in-Charge of the FBI’s Los Angeles Field Office; and Leslie DeMarco, Special Agent-in-Charge of the Internal Revenue Service - Criminal Investigation’s (IRS-CI) Los Angeles Field Office



  • OPA Press Releases

utility

California Company and Two Executives Indicted for Their Alleged Participation in Scheme to Bribe Officials at State-owned Electrical Utility in Mexico

Lindsey Manufacturing Company, an Azusa, Calif., company and two of its executives were indicted today for their alleged roles in a conspiracy to pay bribes to Mexican government officials at the Comisión Federal de Electricidad, a state-owned utility company.



  • OPA Press Releases

utility

Kaua‘i Island Utility Pleads Guilty to Endangered Species Act and Migratory Bird Treaty Act Violation, Agrees to Help Protect Threatened Seabirds

The Kaua‘i Island Utility Cooperative (KIUC) entered a plea agreement today in federal court in Honolulu to resolve violations of the Endangered Species Act and Migratory Bird Treaty Act.



  • OPA Press Releases

utility

California Company, Its Two Executives and Intermediary Convicted by Federal Jury in Los Angeles on All Counts for Their Involvement in Scheme to Bribe Officials at State-Owned Electrical Utility in Mexico

Lindsey Manufacturing Company, an Azusa, Calif., company, two of its executives and a Mexican intermediary today were convicted by a federal jury on all counts for their alleged roles in a scheme to pay bribes to Mexican government officials at the Comisión Federal de Electricidad (CFE), a state-owned utility company.



  • OPA Press Releases

utility

Justice Department Files Lawsuit Against the Twin Cities of Colorado City, Arizona, and Hildale, Utah, and Local Utility Companies Alleging Religious Discrimination

The Justice Department filed a lawsuit today against the town of Colorado City, Ariz.; the city of Hildale, Utah; Twin City Water Authority; and Twin City Power alleging a pattern or practice of police misconduct and violations of federal civil rights laws.



  • OPA Press Releases

utility

US Announces Clean Air Act Settlement with Wisconsin Utility – Dairyland Power Cooperative to Reduce Emissions by More Than 29,000 Tons Annually

The Department of Justice and the U.S. Environmental Protection Agency (EPA) today announced a Clean Air Act settlement with Dairyland Power Cooperative (DPC) that will cover the utility’s three power plants in Alma and Genoa, Wis. DPC has agreed to invest approximately $150 million in pollution control technology that will protect public health and resolve violations of the Clean Air Act.



  • OPA Press Releases

utility

U.S. Announces Clean Air Act Settlement with Wisconsin Utility

The Wisconsin Public Service Corporation (WPS) will invest approximately $300 million in pollution control technology, pay a civil penalty of $1.2 million, and spend $6 million on environmental mitigation projects to resolve violations of the Clean Air Act (CAA), according to the terms of a settlement with the United States.



  • OPA Press Releases

utility

Utility Company Sentenced in Wyoming for Killing Protected Birds at Wind Projects

Duke Energy Renewables Inc., a subsidiary of Duke Energy Corp., based in Charlotte, N.C., pleaded guilty in U.S. District Court in Wyoming today to violating the federal Migratory Bird Treaty Act



  • OPA Press Releases

utility

U.S. Settlement with Minnesota Coal-Fired Utility to Reduce Emissions

In a settlement with the United States, Minnesota Power (MP), an ALLETE company based in Duluth, Minnesota has agreed to install pollution control technology and meet stringent emission rates to reduce harmful air pollution from the company’s three coal-fired power plants located in Cohasset, Hoyt Lakes and Schroeder, Minnesota, the Department of Justice and the U.S. Environmental Protection Agency (EPA) announced today



  • OPA Press Releases

utility

U.S. Settlement with Michigan Utility to Reduce Emissions at Its Coal-Fired Power Plants, Fund Projects to Benefit Environment and Communities

In a settlement with the United States, Consumers Energy, a subsidiary of CMS Energy Corporation, has agreed to install pollution control technology, continue operating existing pollution controls and comply with emission rates to reduce harmful air pollution from the company’s five coal-fired power plants.



  • OPA Press Releases

utility

Clinical utility of 24-h rapid trio-exome sequencing for critically ill infants




utility

Clinical utility of serial analysis of circulating tumour cells for detection of minimal residual disease of metastatic nasopharyngeal carcinoma




utility

Clinical utility of the exosome based ExoDx Prostate(<i>IntelliScore</i>) EPI test in men presenting for initial Biopsy with a PSA 2–10 ng/mL





utility

California Utility Opens First Sustainable Campus as Model Utility Site

Burbank Water & Power opens a sustainable power plant campus as a model for re-adapting industrial sites from water reclamation to solar




utility

Ask Pablo: Why Would My Electric Utility Want Me To Use Less Electricity?

It seems counterintuitive. Is it just greenwashing? Is it due to government regulation? Let's find out.




utility

British utility allows businesses to buy "local" renewable energy

Should we care where our electrons come from?




utility

A major U.S. utility company just pledged to go carbon-free for the first time in American history

Are the tables finally starting to turn?




utility

California utility offers rebates and incentives for going all-electric

SMUD demonstrate that all-electric living is actually cheaper than gas.




utility

Scottish utility goes 100% renewable, pushes electric vehicles too

One of the UK's "Big Six" energy companies has gone a dark shade of green.




utility

Indiana utility to quit coal and cut CO2 90% within 10 years

This ambitious goal is all the more remarkable because NIPSCO is currently 65% coal dependent.




utility

Major German utility rethinks business model, bets on renewables

The future will look nothing like the past when it comes to energy. Chances are, our utilities will look pretty different too.




utility

AEO2020: Alternative Policies - Varying Residential Solar Photovoltaic Utility Rate Structure




utility

It's gull-winged, all-electric and might even come with a flux capacitor: Tesla unveils a new sports utility vehicle

Charge up your flux capacitors! We're going back to the future with Tesla Motors' unveiling of its gull-winged, all-electric sports utility vehicle.




utility

The futility of hope


When Madubhai first heard that a big dam 150 km away would control the waters of the river he revered, he didn't believe the news. He never knew that its waters would one day drown his little world. Neeta Deshpande reports.




utility

Entertaining futility: despair and hope in the time of climate change / Andrew McMurry

Hayden Library - GE195.M455 2018




utility

Youtility : why smart marketing is about help not hype / Jay Baer

Baer, Jay, 1969-




utility

Happiness and utility: essays presented to Frederick Rosen / edited by Georgios Varouxakis, Mark Philp

Online Resource




utility

Utility, publicity, and law: essays on Bentham's moral and legal philosophy / Gerald J. Postema

Dewey Library - B1574.B34 P67 2019




utility

O-Cyclopropyl hydroxylamines: gram-scale synthesis and utility as precursors for N-heterocycles

Org. Biomol. Chem., 2020, 18,3281-3287
DOI: 10.1039/D0OB00611D, Paper
Kaitlyn Lovato, Urmibhusan Bhakta, Yi Pin Ng, László Kürti
A novel and scalable synthesis of O-cyclopropyl hydroxylamines is reported. These compounds are bench-stable and have been shown to be practical precursors for the synthesis of N-heterocycles via a di-heteroatom [3,3]-sigmatropic rearrangement.
The content of this RSS Feed (c) The Royal Society of Chemistry




utility

Mathematical topics on representations of ordered structures and utility theory: essays in honor of Professor Ghanshyam B. Mehta / Gianni Bosi, María J. Campión, Juan C. Candeal, Esteban Indurain, editors

Online Resource




utility

Technologies and properties of modern utility materials XXI: selected, peer reviewed papers from the XXI Conference on Technologies and Properties of Modern Utility Materials (TPMUM 2013), May 17, 2013, Katowice, Poland / edited by Jacek Medala and Paweł

Hayden Library - TA481.C67 2014




utility

JAMA Cardiology : Utility of 90-Day vs 30-Day Mortality Quality Metrics for Aortic Valve Replacement Outcomes

Interview with Tsuyoshi Kaneko, MD, and Sameer A Hirji, MD, authors of Utility of 90-Day Mortality vs 30-Day Mortality as a Quality Metric for Transcatheter and Surgical Aortic Valve Replacement Outcomes, and Michael J. Mack, MD, author of Ninety-Day Outcome Assessment After Transcatheter and Surgical Aortic Valve Replacement—Is the Juice Worth the Squeeze?




utility

Pentachlorophenol is on its way out as a utility pole preservative. Here's what might take its place

Phaseout is pushing a slow-to-change industry to look at alternatives




utility

The utility of morphological, ITS molecular and combined datasets in estimating the phylogeny of the cortinarioid sequestrate fungi / by Anthony Francis

Francis, Anthony





utility

The Need to Improve the Clinical Utility of Direct-to-Consumer Genetic Tests: Either Too Narrow or Too Broad

This Viewpoint summarizes current shortcomings in direct-to-consumer genetic tests, which often lack clinical utility for consumers, and explains how tests that encompass entire genes and include only genes with well-established risk estimates and medical management guidelines could provide more valuable insight into their disease risk.




utility

Toppled utility poles line a brick road in Ybor City after the hurricane of 1921




utility

Utility of positive peer reporting to improve interactions among children in foster care




utility

An integrated optimal design method for utility power distribution systems




utility

Transportation utility fees




utility

Lake Park utility poles