Tissue slices and whole organisms offer substantial challenges to fluorescence imaging. Autofluorescence and absorption via intrinsic chromophores, such as flavins, melanin, and hemoglobins, confound and degrade output from all fluorescent tags. An “optical window,” farther red than most autofluorescence sources and in a region of low hemoglobin and water absorbance, lies between 650 and 900 nm. This valley of relative optical clarity is an attractive target for fluorescence-based studies within tissues, intact organs, and living organisms. Novel fluorescent tags were developed herein, based upon a genetically targeted fluorogen activating protein and cognate fluorogenic dye that yields emission with a peak at 733 nm exclusively when complexed as a “fluoromodule”. This tool improves substantially over previously described far-red/NIR fluorescent proteins in terms of brightness, wavelength, and flexibility by leveraging the flexibility of synthetic chemistry to produce novel chromophores.

A thermal dye image receiver element has a substrate comprising a voided compliant layer and metalized layer. Disposed on the metalized layer is an opacifying layer that includes an opacifying agent and a dye receiving layer. This thermal dye image receiver element can be a duplex element with image receiving layers on both sides of the substrate, and it can be used in association with a thermal donor element to provide a thermal image on either or opposing sides of the receiver element. The metalized layer provides increased specular reflectance under resulting thermal dye images.

A method and system uniquely capable of generating thermal bubbles for improved ultrasound imaging and therapy. Several embodiments of the method and system contemplates the use of unfocused, focused, or defocused acoustic energy at variable spatial and/or temporal energy settings, in the range of about 1 kHz-100 MHz, and at variable tissue depths. The unique ability to customize acoustic energy output and target a particular region of interest makes possible highly accurate and precise thermal bubble formation. In an embodiment, the energy is acoustic energy. In other embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents (including monopolar and bipolar radio-frequency current). In an embodiment, the energy is various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling.

The present invention pertains to systems and methods for the capture of information regarding scenes using single or multiple three-dimensional LADAR systems. Where multiple systems are included, those systems can be placed in different positions about the imaged scene such that each LADAR system provides different viewing perspectives and/or angles. In accordance with further embodiments, the single or multiple LADAR systems can include two-dimensional focal plane arrays, in addition to three-dimensional focal plane arrays, and associated light sources for obtaining three-dimensional information about a scene, including information regarding the contours of the objects within the scene. Processing of captured image information can be performed in real time, and processed scene information can include data frames that comprise three-dimensional and two-dimensional image data.

An integrated swept wavelength tunable optical source uses a narrowband filtered broadband signal with an optical amplifier and self-tracking filter. This source comprises a micro optical bench, a source for generating broadband light, a tunable Fabry Perot filter, installed on the bench, for spectrally filtering the broadband light from the broadband source to generate a narrowband tunable signal, an amplifier, installed on the bench, for amplifying the tunable signal. The self-tracking arrangement is used where a single tunable filter both generates the narrowband signal and spectrally filters the amplified signal. In some examples, two-stage amplification is provided. The use of a single bench implementation yields a low cost high performance system. For example, polarization control between components is no longer necessary.

A projection exposure tool for microlithography for imaging mask structures of an image-providing substrate onto a substrate to be structured includes a measuring apparatus configured to determine a relative position of measurement structures disposed on a surface of one of the substrates in relation to one another in at least one lateral direction with respect to the substrate surface and to thereby simultaneously measure a number of measurement structures disposed laterally offset in relation to one another.

The invention relates to compounds and methods for targeting radionuclide-based imaging agents to cells having receptors for a vitamin, or vitamin receptor binding derivative or analog thereof, by using such a vitamin as the targeting ligand for the imaging agent. The vitamin-based compounds can be used to target radionuclides to cells, such as a variety of tumor cell types, for use in diagnostic imaging of the targeted cells.

Chelators of the formulae (I), (II) and (III) and tricarbonyl complexes of radioisotopes of Tc and Re bound to them, for use in myocardial imaging.

A business form with laser compatible punch-out card and the methods of making the combination. The card is permanently adhered to a perforated backer sheet, the periphery of which extends beyond the card and is coated with adhesive for application to the bottom surface of a form containing a hole such that the card is disposed within the hole. The card and attached portion of the backer sheet can then be removed from the card-in-form combination by breaking the perforations. The card is die cut from card stock laminated to the backer layer and is prepared for application to the form by stripping a waste matrix of card material from the laminate through the use of patterned release material.

A combined multi-lumen central access catheter and an embolic filter, further comprising an imaging modality to facilitate intravascular imaging of the filter.

A combined multi-lumen central access catheter and an embolic filter, further comprising an imaging modality to facilitate intravascular imaging of the filter.

There is provided solid imaging methods and apparatus for making three-dimensional objects from solid imaging material. A tray with a film bottom is provided to hold solid imaging material that is selectively cured into cross-sections of the three-dimensional object being built. A coater bar is moved back and forth over the film to remove any uncured solid imaging material from a previous layer and to apply a new layer of solid imaging material. A sensor is provided to measure the amount of resin in the tray to determine the appropriate amount of solid imaging material to be added, from a cartridge, for the next layer. A shuttle, which covers the tray when the exterior door to the solid imaging apparatus is opened for setting up a build or removing a three-dimensional object, can also be used to move the coater bar and to selectively open one or more valves on the cartridge to dispense the desired amount of solid imaging material.

An image forming apparatus including a control unit configured to cause the light irradiation unit to irradiate the photosensitive member at an image forming portion to which toner particles adhere with light emitted from the light source by a first light emission amount, and cause the light irradiation unit to irradiate the photosensitive member at a non-image forming portion to which no toner particles adhere with light emitted from the light source by a second light emission amount that is smaller than the first light emission amount. The image forming apparatus further includes an adjusting unit configured to adjust the first light emission amount and the second light emission amount, and an acquisition unit configured to acquire information relating to a speed of surface of the photosensitive member. The adjusting unit is configured to change the second light emission amount according to information acquired by the acquisition unit.

A 2-D scanning system uses a fast-rotating raster-polygon as a single scanning component to produce straight scan lines over a 2-D image surface. An approach angle of incident light beams to the raster-polygon is selected to minimize pin-cushion distortion of scan lines introduced by polygon scanning on the image surface, and a tilt angle of the rotational axis of the raster-polygon is selected to position said polygon-scanning distortion symmetrically on the image surface. In addition, scan optics are configured to generate a predetermined amount of barrel distortion of scan lines on the image surface to compensate for pin-cushion distortion introduced by polygon scanning.

An imaging apparatus includes a front lens group including a front lens element and a reflector, a movable frame supporting the front lens element, and a driver driving the movable frame to reduce image shake. The driver includes first and second voice coil motors, each including a coil and a magnet. The magnets are positioned orthogonal to each other in a plane orthogonal to a first optical axis that passes through the front lens element. The first and second voice coil motors are positioned on opposite sides of a first plane, including the first optical axis and a second optical axis that extends from the reflector. Centers of each magnet and coil are on one side of a second plane, including the first optical axis and is orthogonal to the first plane. The magnets are inclined and approach the first plane in a direction away from the second plane.

The present invention relates to a moving member control apparatus that makes sure unerring control of a moving member having an ill-balanced structure and an imaging apparatus that incorporates that control apparatus.

The CPU acquires the output of an angular velocity sensor and performs image shake correction. An angle 1 calculating unit integrates a signal from which an offset component is removed to calculate an angle 1. An angular velocity subtraction amount calculating unit calculates an angular velocity subtraction amount based on a signal obtained by subtracting a first offset from the output of the angular velocity sensor and a signal obtained by subtracting a second offset from the output of the angle 2 calculating unit. An angle 2 calculating unit integrates a signal obtained by subtracting the angular velocity subtraction amount from the output of the angular velocity sensor to calculate an angle 2. The CPU performs image shake correction based on the angle 1 prior to operation of a release SW, whereas the CPU performs image shake correction based on the angle 2 after operation of the release SW.

An imaging apparatus for performing wireless communication with an external device. An instruction transmitting unit transmits an operation instruction to the external device. A response signal receiving unit receives a response signal from the external device. A first controlling unit starts a first operation relating to an imaging process in a case that a first time passes from a point of receiving the response signal by the response signal receiving unit. The external device executes a second operation relating to the imaging process in a case that a second time passes from a point of transmitting the response signal from the external device to the imaging apparatus.

A viewfinder 3 includes a finder optical system S2 including first and second lens groups L1, L2; a zoom frame 6 provided with first and second cam grooves 63, 64 configured to rotate about an optical axis A2 to move the first and second lens groups L1, L2 in the optical axis direction in accordance with the shapes of the first and second cam grooves 63, 64; and a diopter adjuster 9 configured to adjust the diopter of the finder optical system S2. The diopter adjuster 9 changes the position of the zoom frame 6 in the optical axis direction to adjust the diopter of the finder optical system S2, and adjusts, during rotation of the zoom frame 6, the position of the zoom frame 6 in the optical axis direction such that the diopter of the finder optical system S2 is maintained.

An ophthalmologic imaging apparatus includes an observation light source configured to generate infrared light for illuminating a subject's eye via an illumination optical system, an imaging unit configured to receive light returned from the subject's eye via an imaging optical system, and an electronic shutter control unit configured to refresh charge generated caused by light received by the imaging unit in response to turning off of the observation light source.

An imaging apparatus includes a shooting lens having a focus lens for adjusting a degree of focus on an imaging plane; an image sensor converting an optical image of a photographic subject to an electric image signal and outputting it; a confirmation image creator creating a focus state confirmation image in which a part, or a whole of an image expressed by the image signal is enlarged; a display displaying the focus state confirmation image; and a focus evaluation value calculator calculating a focus evaluation value based on the image signal; wherein when a state of an inclination of change in a focus evaluation value calculated at a plurality of positions of the focus lens while moving the focus lens is different from a state of an inclination of change in a focus evaluation value calculated immediately before, the focus state confirmation image is displayed on the display.

A method of reducing light damage in a shutterless imaging device includes receiving a signal from a hardware device. The signal from the hardware devices is analyzed. In response to the analysis of the signal from the hardware device, a lens of the shutterless imaging device is adjusted. Adjusting the lens spreads out energy of far-field image light incident on an image sensor of the shutterless imaging device.

A digital camera is provided with a vertically long camera body having an approximately rectangular solid shape. An LCD panel provided in a rear surface of the camera body is arranged such that longitudinal directions of the display screen and the camera body correspond to each other. The digital camera is operated through a touch panel provided in a lower portion of the display screen. In a taking mode, an image is displayed in a small size on an upper portion of the display screen. In reproducing, the camera body is rotated sideways by 90 degree. In a reproducing mode, display posture of the image is also rotated by 90 degree, and the image is displayed in a large size on the entire display screen.

A counter configured to perform counting at both edges of an input clock to output an additional value or a subtraction value for a previous count value and a next count value includes a first latch circuit that latches the input clock, a second latch circuit that latches an output from the first latch circuit, a holding section that holds data of the 0th bit of a count value, and a correction section that performs count correction on data of the first and subsequent bits of the count value on the basis of an output of the second latch circuit.

A ring oscillator circuit causing a pulse signal to circulate around a circle to which an even number of inverting circuits are connected in a ring, wherein one of the inverting circuits is a first starting inverting circuit, which drives a first pulse signal according to a control signal, another of the inverting circuits is a second starting inverting circuit, which drives a second pulse signal based on a leading edge of the first pulse signal, still another is a third starting inverting circuit, which drives a third pulse signal based on the leading edge of the first pulse signal after the second pulse signal is driven, and the first to third starting inverting circuits are arranged within the circle of the inverting circuits in order of the third, second, and first pulse signals in traveling directions of the pulse signals.

Imaging apparatus and methods for bindery systems. An example apparatus disclosed herein includes a platform having a plurality of openings to provide suction through a surface of the platform and a first track that moves across the surface of the platform. The first track has a plurality of apertures to fluidly couple the suction to an upper surface of the first track.

A vehicular imaging and display system includes a rear backup camera at a rear portion of a vehicle, a video processor for processing image data captured by the rear camera, and a video display screen responsive to the video processor to display video images. During a reversing maneuver of the equipped vehicle, the video display screen displays video images captured by the rear camera. During forward travel of the equipped vehicle, the video display screen is operable to display images representative of a portion of the field of view of the rear camera to display images representative of an area sideward of the equipped vehicle responsive to at least one of (a) actuation of a turn signal indicator of the vehicle, (b) detection of a vehicle in a side lane adjacent to the equipped vehicle and (c) a lane departure warning system of the vehicle.

Currency bills are received, transported, and imaged to produce image data from which a visually readable image of each currency bill can be reproduced. Each of the currency bills includes a denomination, a serial number, and a set of secondary identifiers. One of the currency bills is determined to be a suspect bill. The suspect bill serial number is attempted to be extracted from the image data associated with the suspect bill. In response to failing to extract a complete serial number of the suspect bill, a serial number field in a suspect report is populated with a serial number snippet image.

An improved document scanning device and a scanning method for checking the transparency and thickness of an identification document. In a preferred embodiment, any one surface of the document is illuminated by the illumination source facing the said surface and the opposite surface of the document is captured by the camera. The amount of light that passes through the illuminated surface of the document is measured and contrasted with the amount of light that passes through the same surface of a reference or original document. The scanning method is also capable of validating an identification document by detecting and authenticating any laser image imprinted on such document.

An imaging reader reads targets by image capture in both handheld and hands-free modes of operation. Upon detection of the mode of operation, a controller sets the resolution and frame rate of a solid-state imaging sensor to different values in each mode to optimize target reading performance in each mode.

Medical imaging equipment is provided. The medical imaging equipment comprises a support assembly, an arc-shaped member slidably mounted on the support assembly, a radiation source mounted on the arc-shaped member in the vicinity of a first distal end of the arc-shaped member and being oriented to radiate along the direction of an imaging axis, and a detector mounted on the arc-shaped member in the vicinity of the second distal end of the arc-shaped member and being oriented to face the source along the imaging axis, wherein the radiation source and the detector are respectively mounted on one side and the other of the mid plane of the arc-shaped member.

A system and method for nodule boundary visualization superimposed on a scan image, including generating phantom image measurements of at least one synthetic calibration object in relation to a body to calibrate a scanner; acquiring a first image of a nodule on the calibrated scanner; computing and marking a boundary on the image; displaying the first image with the boundary superimposed over the first image; presenting the initial boundary to a user for modification where the user can add one or more modification points to the image to create a modified boundary that is encompassed by the one or more modification points; once the user has marked the one or more modification points on the image, computing an updated boundary that adapts to include the new points.

An X-ray arrangement is suitable to record absorption, phase contrast, and dark field images of an object. The visibility of low absorbing specimens is improved and required radiation dose is reduced. The assembly includes an X-ray source; two or more gratings; a position-sensitive detector with spatially modulated detection sensitivity; a recorder for recording the images; an evaluator for evaluating the intensities for each pixel to identify the characteristic of the object for each individual pixel as an absorption and/or a differential phase contrast and/or an x-ray scattering dominated pixel. Images are collected by rotating from 0 to n or 2n either the sample or the assembly. The gratings are produced with planar geometry. The X-rays pass through the gratings parallel to the substrate. The grating structures extend along the X-ray path which determines the phase shift. The attenuation of the X-rays caused by the grating structures is no longer given by the thickness, but by the length of the grating structures.

A press plate that includes: a plate shaped press portion that is capable of resilient deformation; a first slit that is provided to a first wall portion of a support body with length direction along a first edge portion of the press portion, and that penetrates the first wall portion; second slits that are provided to a second wall portions of the support body with length direction along second edge portions of the press portion, and that penetrate the second wall portions; and a first corner portion slit that is provided straddling a corner portion between the first wall portion and the second wall portion and penetrating the corner portion, that is connected to the first slit, and that is disposed at a separation to the second slit.

A computer-implemented method for gain calibration is provided. The method includes sorting the calibration data of each pixel location from the offset-corrected X-ray image data into a sequence. The method also includes removing part of the calibration data from one end or both ends of the respective sequence for each pixel location. The method further includes averaging the calibration data remaining within each respective sequence to obtain an average pixel value for each pixel location. The method yet further includes generating a gain map based on the average pixel value for each pixel location.

A power converter is configured to include an inverter which converts a DC output into an AC voltage of a predetermined frequency, and a high voltage generator which receives an output from output terminals of the inverter and boosts the output to a desired high DC voltage. The high voltage generator includes a transformer, and the primary windings of the transformer are connected to the output terminals of the inverter in parallel by conductive wires connected to both ends of each primary winding. Further, a current sensor is provided to detect a current flowing through each of the primary windings, and a control unit determines abnormalities of a path of the inverter and the primary windings on the basis of a value of the current sensor.

In a construction having a radiation tube in an envelope filled with an insulating liquid, a radiation generating apparatus which realizes a miniaturization of the apparatus, an improvement of a withstanding voltage between the envelope and the radiation tube, and a decrease in attenuation amount of the radiation and a radiation imaging apparatus using the radiation generating apparatus are provided. The radiation generating apparatus has an envelope 12 having a first window 27 for transmitting the radiation, a radiation tube 14 enclosed in the envelope 12 and having a second window 19 for transmitting the radiation at a position in opposition to the first window 27, and an insulating liquid 13 filled between the envelope 12 and the radiation tube 14. A solid-state insulating member 28 is placed between the first window 27 and its periphery and the second window 19 and its periphery.

An imaging apparatus having a ring-shaped gantry is provided. The gantry has a rotor arrangement rotating therein and a radiation source as well as at least one radiation detector. The gantry has at least one gantry segment which can be detached from the ring shape to allow the gantry to be opened laterally. The gantry is arranged on a supporting structure so as to be movable in space. The supporting structure is a ceiling-mounted stand having at least two degrees of freedom of movement. The gantry has at least two radiation sources disposed offset by an angle on the rotor arrangement and associated with each of which is at least one radiation detector.

A system and a method for acquiring image data of a subject with an imaging system are provided. The system can include a gantry that completely annularly encompasses at least a portion of the subject, and a source positioned within the gantry. The source can be responsive to a signal to output at least one pulse. The system can include a multi-row detector positioned within the gantry. The multi-row detector can be in alignment with the source and sets multi-row detector data based on the detected at least one signal. The system can include a flat panel detector positioned within the gantry. The flat panel detector can in alignment with the source and sets flat panel detector data based on the detected at least one signal. The system can include an image acquisition control module that determines which of the multi-row detector and the flat panel detector to use.

To provide an X-ray imaging apparatus capable of easily adjusting the sensitivity or capable of easily extracting the amount of refraction of X-rays. An X-ray imaging apparatus irradiating an object to be measured with an X-ray beam from an X-ray source that generates X-rays of a first energy and X-rays of a second energy different from the first energy to measure an image of the object to be measured includes an attenuator and a detector. The attenuator attenuates the X-ray beam transmitted through the object to be measured and is configured so as to vary the amount of attenuation of the X-rays depending on a position on which the X-ray beam is incident. The detector detects the X-ray beam transmitted through the attenuator and is configured so as to detect the X-rays of the first energy and the second energy.

A method and apparatus is provided for collecting data and generating synthesized data from the collected data. For example, a request for an image may be received from a requestor and at least one data capture device may be identified as capable of providing at least a portion of the requested image. A request may be sent to identified data capture devices to obtain an image corresponding to the requested image. Multiple images may be received from the data capture devices and may further be connected or stitched together to provide a panoramic, 3-dimensional image of requested subject matter.

Provided is an A/D converter including an input terminal, a reference signal line for supplying a reference signal which changes temporally, a comparator, a correction capacitor connected to an inverting input terminal of the comparator; and an output circuit which outputs digital data corresponding to an analog signal input to the input terminal. In a first state in which a total voltage of a first analog signal and an offset voltage of the comparator is held in the correction capacitor, a second analog signal input to the input terminal is supplied to a non-inverting input terminal of the comparator, and the second analog signal or the total voltage is changed using the reference signal, thereby outputting, from the output circuit, digital data.

According to one embodiment, a solid state imaging device includes a sensor substrate having a plurality of pixels formed on an upper face, a microlens array substrate having a plurality of microlenses formed and a connection post with one end bonded to a region between the microlenses on the microlens array substrate and with the other end bonded to the upper face.

An organic compound and a photoelectric conversion device containing the organic compound are disclosed. The organic compound and device realize high photoelectric conversion efficiency, low dark current and high-speed responsivity. It has been found that when this organic compound and an n-type semiconductor are used in combination, high-speed responsivity can be realized while maintaining high heat resistance, an aspect of which has not been seen when the connection part between a donor part and an acceptor part is a phenylene group.

A method, consisting of passing a cylindrical carbon fiber through a press so as to produce a flat ribbon. The method further includes weaving multiple strands of the flat ribbon together to create a cylindrical braid.

An input receptacle receives currency bills and checks. A transport mechanism transports the bills and checks along a transport path to an output receptacle. An image scanner, adjacent the transport path, is configured to generate one or more electrical signals from which image data can be derived. The image data is reproducible as a visually readable image of at least a portion of each of the plurality of documents. A controller is configured to determine a denomination of each of the currency bills. In response to the controller not determining a denomination of one of the currency bills, the controller flags the currency bill as a no-call document by causing at least a portion of the image data to be displayed as a visually readable image of the flagged currency bill on the display.

Printers, methods, and apparatus to filter imaging oil are disclosed. An example apparatus to filter imaging oil, includes adjacent electrodes and a switching circuit. The example switching circuit selectively generates an electrostatic field between the adjacent electrodes to cause particles suspended in the imaging oil between the adjacent electrodes to adhere to at least one of the adjacent electrodes, and generates an alternating electric field between the adjacent electrodes to cause the particles to be detached from the adjacent electrodes.

An apparatus and method for positioning and aligning one or more pre-punched printing plates on a cylinder for imaging a plate in a computer-to-plate drum imaging device. The apparatus includes an imaging cylinder and a registration device connectable to the cylinder. The apparatus includes at least one groove and one pair of register pins, with a first register pin in a fixed position, and a second register pin movable in the groove to a second position, and collinear with the first register pin in the axial direction of the cylinder, arranged such that when connected to the cylinder, the registration device allows a plurality of pre-punched printing plates with variable widths to be positioned and aligned on the cylinder with simplicity.

A laser-engraveable flexographic printing precursor or patternable element comprises a laser-engraveable layer having two orthogonal dimensions. This laser-engraveable layer comprises one or more elastomeric resins and non-metallic fibers that are oriented in the laser-engraveable layer predominantly in one of its two orthogonal dimensions. The non-metallic fibers have an average length of at least 0.1 mm and an average diameter of at least 1 μm. The oriented non-metallic fibers reduce curl and shrinkage in the precursor and improve print quality and press life.

A refrigerator includes a sensing system for detecting multiple physical characteristics of ice cubes in an ice cube storage bin. The system includes a digital image capture device coupled to a digital image analyzing system which captures digital images of the ice cube storage bin intermittently and compares the images to detect the presence of ice clumps. In addition, the digital image analyzing system evaluates the edges, ice size and/or image intensity of the ice cubes in the images in order to determine the presence of stale ice. An algorithm is utilized to estimate the volume of ice within the bin based on the number of pixels in an ice bin image, the number of pixels of the ice within the bin, and a known volume of the ice bin. Notifications for clumped ice, stale ice and ice volume within the bin are sent to a user interface.